Search filters

List of works by Torben Hansen

1H-MRS Measured Ectopic Fat in Liver and Muscle in Danish Lean and Obese Children and Adolescents

scientific article

1H-MRS measured ectopic fat in liver and muscle is associated with the metabolic syndrome in Danish girls but not in boys with overweight and obesity.

scientific article published on 14 September 2016

35th Annual Meeting of the European Association for the Study of Diabetes

article

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999

article

A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects.

scientific article

A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites.

scientific article published in October 2005

A Functional Amino Acid Substitution in the Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR) Gene Is Associated With Lower Bone Mineral Density and Increased Fracture Risk

article

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

scientific article published on 27 April 2018

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

scientific article published on 10 May 2017

A Genome-Wide Scan in Families With Maturity-Onset Diabetes of the Young: Evidence for Further Genetic Heterogeneity

article

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

scientific article published on 24 March 2017

A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease

scientific article published on September 2015

A combined analysis of 48 type 2 diabetes genetic risk variants shows no discriminative value to predict time to first prescription of a glucose lowering drug in Danish patients with screen detected type 2 diabetes

scientific article

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

scientific article

A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis

scientific article

A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects

scientific article

A computational framework to integrate high-throughput ‘-omics’ datasets for the identification of potential mechanistic links

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents

scientific article

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

scientific article published on June 2016

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

scientific article published on 25 September 2011

A glycogene mutation map for discovery of diseases of glycosylation

scientific article

A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes.

scientific article

A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults

scientific article published in Nature Communications

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

scientific article

A metagenome-wide association study of gut microbiota in type 2 diabetes

scientific article (publication date: 4 October 2012)

A novel -192c/g mutation in the proximal P2 promoter of the hepatocyte nuclear factor-4 alpha gene (HNF4A) associates with late-onset diabetes

scientific article published in June 2006

A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

article

A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene

scientific article

A possible association between a dysfunctional skin barrier (filaggrin null-mutation status) and diabetes: a cross-sectional study

scientific article

A prevalent amino acid polymorphism at codon 98 (Ala98Val) of the hepatocyte nuclear factor-1alpha is associated with maturity-onset diabetes of the young and younger age at onset of type 2 diabetes in Asian Indians.

scientific article published in October 2005

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A role for coding functional variants in HNF4A in type 2 diabetes susceptibility

scientific article (publication date: 2011)

A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes

scientific article

A study of associations between early DHA status and fatty acid desaturase (FADS) SNP and developmental outcomes in children of obese mothers

scientific article published on 6 February 2017

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

scientific article published on 01 October 2019

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

scientific article (publication date: June 2007)

A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

scientific article

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

scientific article

ADAMTS9 Regulates Skeletal Muscle Insulin Sensitivity Through Extracellular Matrix Alterations

scientific article published on 09 January 2019

Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis

scientific article published on 01 November 2019

Aberrant intestinal microbiota in individuals with prediabetes.

scientific article published on 29 January 2018

Abstracts from the 53rd European Society of Human Genetics (ESHG) Conference: Interactive e-Posters

scientific article published on 01 December 2020

Activated T lymphocytes disappear from circulation during endotoxemia in humans

scientific article published on May 2002

Adults with pathogenic MC4R mutations have increased final height and thereby increased bone mass

scientific article published on 30 August 2019

Alcohol consumption and its interaction with adiposity-associated genetic variants in relation to subsequent changes in waist circumference and body weight

scientific article

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

scientific article published in October 1993

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

An Improved Method for High Quality Metagenomics DNA Extraction from Human and Environmental Samples

scientific article

An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese

scholarly article by Anne-Sofie Graae et al published August 2018 in Diabetologia

An integrated catalog of reference genes in the human gut microbiome

scientific article

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

scientific article published in August 2012

Archaic Adaptive Introgression in TBX15/WARS2.

scientific article

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion

scientific article published on 20 January 2015

Association between Neuromedin U Gene Variants and Overweight and Obesity

article

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

scientific article published on 04 September 2019

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

scientific article published on 30 October 2018

Association of genetic variants previously implicated in coronary artery disease with age at onset of coronary artery disease requiring revascularizations

scientific article published in 2019

Association of the beta3-adrenergic receptor Trp64Arg polymorphism with common metabolic traits: studies of 7605 middle-aged white people

scientific article

Association of the calpain-10 gene with type 2 diabetes in Europeans: Results of pooled and meta-analyses

article

Association studies of genetic scores of serum vitamin B12 and folate levels with symptoms of depression and anxiety in two danish population studies

scientific article

Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals

scientific article published on 28 September 2011

Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged D

article by Niels Grarup et al published September 2008 in Diabetes

Associations between thyroid-stimulating hormone, blood pressure and adiponectin are attenuated in children and adolescents with overweight or obesity

scientific article published on 01 December 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis.

scientific article

Atorvastatin for prevention of disease progression and hospitalisation in liver cirrhosis: protocol for a randomised, double-blind, placebo-controlled trial

scientific article published on 23 January 2020

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

scientific article published on 01 September 2018

Author Correction: Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

scientific article published on 21 December 2020

Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease ⬇️

scientific article

Birth weight variants are associated with variable fetal intrauterine growth from 20 weeks of gestation.

scientific article published on 30 May 2018

Blood pressure levels in male carriers of Arg82Cys in CD300LG

scientific article

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

scientific article

Bone turnover, calcium homeostasis, and vitamin D status in Danish vegans

scientific article

Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

scholarly article by Elahu G. Sustarsic published in July 2018

Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study

scientific article

Cardiovascular outcomes and systemic anti-inflammatory drugs in patients with severe psoriasis: 5-year follow-up of a Danish nationwide cohort

scientific article published on 10 October 2014

Cardiovascular risk in patients with sleep apnoea with or without continuous positive airway pressure therapy: follow-up of 4.5 million Danish adults

scientific article published on 17 September 2014

Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone

scientific article (publication date: 14 September 2016)

Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test

scientific article published on 19 October 2010

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

scientific article

Changes in gastrointestinal hormone responses, insulin sensitivity, and beta-cell function within 2 weeks after gastric bypass in non-diabetic subjects

scientific article published in July 2012

Changes in short- and long-term cardiovascular risk of incident diabetes and incident myocardial infarction—a nationwide study

scholarly article by M. L. Norgaard et al published 9 May 2010 in Diabetologia

Characterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alpha

scientific article

Childhood obesity treatment; Effects on BMI SDS, body composition, and fasting plasma lipid concentrations

scientific article published on 14 February 2018

Clinical consequences of hospital variation in use of oral anticoagulant therapy after first-time admission for atrial fibrillation

scientific article published in March 2009

Clinical profiles of post-load glucose subgroups and their association with glycaemic traits over time: an IMI-DIRECT study

scientific article published on 17 October 2020

Clopidogrel discontinuation after myocardial infarction and risk of thrombosis: a nationwide cohort study

scholarly article by M. Charlot et al published 12 July 2012 in European Heart Journal

Cognitive Function in Adult Offspring of Women with Gestational Diabetes–The Role of Glucose and Other Factors ⬇️

scientific article published on June 28, 2013

Cohort Profile: The Health2006 cohort, Research Centre for Prevention and Health

article

Cohort description: The Danish study of Functional Disorders

scientific article published on 23 February 2017

Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut.

scientific article published on 27 June 2016

Combined analyses of 20 common obesity susceptibility variants ⬇️

scientific article

Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene–gene interaction

article

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common nonsynonymous variants in PCSK1 confer risk of obesity

article

Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study

scientific article published on 11 November 2015

Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses

scientific article published on 16 March 2018

Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites

scientific article published in March 2007

Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes

article

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

scientific article

Comparison of accuracy of diabetes risk score and components of the metabolic syndrome in assessing risk of incident type 2 diabetes in Inter99 cohort

scientific article (publication date: 2011)

Copy number variations of chromosome 16p13.1 region associated with schizophrenia

scientific article published on 29 September 2009

Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

scientific article published in Nature

DNA methylation and gene expression of HIF3A: cross-tissue validation and associations with BMI and insulin resistance

scientific article published on 02 September 2016

Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study

scientific article

Describing the fecal metabolome in cryogenically collected samples from healthy participants

scientific article published on 21 January 2020

Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study

scientific article

Design of association studies with pooled or un-pooled next-generation sequencing data

scientific article

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Diabetic cats have decreased gut microbial diversity and a lack of butyrate producing bacteria

scientific article published on 18 March 2019

Diagnosis and treatment of maturity onset diabetes of the young type 3 ⬇️

scientific article published in February 2018

Dietary ascorbic acid and subsequent change in body weight and waist circumference: associations may depend on genetic predisposition to obesity--a prospective study of three independent cohorts.

scientific article

Dietary modulation of the gut microbiota--a randomised controlled trial in obese postmenopausal women

scientific article

Differing prognostic value of pulse pressure in patients with heart failure with reduced or preserved ejection fraction: results from the MAGGIC individual patient meta-analysis

scientific article

Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium

scientific article

Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes

scientific article published on 19 January 2015

Discovery of novel heart rate-associated loci using the Exome Chip

scientific article

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

scientific article published on 2 December 2015

Distance distributions in proteins: a six-parameter representation

scientific article published on 01 September 1996

Disturbed eating behaviours do not impact treatment response in a paediatric obesity chronic care treatment programme

scientific article published on 06 November 2019

Does DNA methylation of PPARGC1A influence insulin action in first degree relatives of patients with type 2 diabetes?

scientific article

Dyslipidemia and reference values for fasting plasma lipid concentrations in Danish/North-European White children and adolescents

scientific article

EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families

scientific article

Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis

scientific article published on 11 December 2018

Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism

scientific article published on 12 November 2015

Effect of chenodeoxycholic acid and the bile acid sequestrant colesevelam on glucagon-like peptide-1 secretion

scientific article

Effect of the interaction between diet composition and the PPM1K genetic variant on insulin resistance and β cell function markers during weight loss: results from the Nutrient Gene Interactions in Human Obesity: implications for dietary guidelines

article

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

scientific article published on 01 June 2019

Effects of RYGB on energy expenditure, appetite and glycaemic control: a randomized controlled clinical trial.

scientific article published on 25 August 2015

Effects of a Family-Based Childhood Obesity Treatment Program on Parental Weight Status

scientific article

Efficacy and Safety of Glimepiride With or Without Linagliptin Treatment in Patients With HNF1A Diabetes (Maturity-Onset Diabetes of the Young Type 3): A Randomized, Double-Blinded, Placebo-Controlled, Crossover Trial (GLIMLINA)

scientific article published on 13 July 2020

Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon.

scientific article

Enterotypes of the human gut microbiome

scientific article

Enterotypes of the human gut microbiome

scientific article published in Nature

Environmental spread of microbes impacts the development of metabolic phenotypes in mice transplanted with microbial communities from humans

scientific article published on 18 November 2016

Erratum to: 'Intake of Macro- and Micronutrients in Danish Vegans'

scientific article published on 9 February 2016

Erratum: Addendum: Enterotypes of the human gut microbiome

scientific article published in Nature

Erratum: Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia

scholarly article by Johan Rung et al published October 2009 in Nature Genetics

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Estimates of insulin sensitivity and β-cell function in children and adolescents with and without components of the metabolic syndrome

scientific article published in January 2017

Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization

scientific article

Estimation of allele frequency and association mapping using next-generation sequencing data

scientific article

Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model

scientific article published on 29 January 2014

Evidence for shared genetics between physical activity, sedentary behaviour and adiposity-related traits

scientific article published on 22 December 2020

Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

scientific article published on 5 January 2018

Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes.

scientific article published in July 2005

Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene

scientific article

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

scientific article published on 19 November 2012

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 06 June 2019

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Expanding the range of ZNF804A variants conferring risk of psychosis

scientific article published on 5 January 2010

Extracellular Vesicle Encapsulated MicroRNAs in Patients with Type 2 Diabetes Are Affected by Metformin Treatment

scientific article published on 07 May 2019

FADS and PPARG2 Single Nucleotide Polymorphisms are Associated with Plasma Lipids in 9-Mo-Old Infants

scientific article published on 01 May 2019

FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans

scientific article

FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness

scientific article

FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.

scientific article

FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials

scientific article

FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

scientific article

Familial mild hyperglycemia associated with a novel ABCC8-V84I mutation within three generations

scientific article published on 9 January 2011

Fast pouch emptying, delayed small intestinal transit, and exaggerated gut hormone responses after Roux-en-Y gastric bypass

article

Fasting serum levels of ferritin are associated with impaired pancreatic beta cell function and decreased insulin sensitivity: a population-based study

scientific article published on 14 December 2014

Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men

scientific article

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

scientific article published on 08 October 2018

First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes

scientific article published on 25 September 2018

Functional SOCS1 polymorphisms are associated with variation in obesity in whites.

scientific article published in March 2009

Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population

scientific article published on 11 April 2016

Functional screening identifies miRNAs influencing apoptosis and proliferation in colorectal cancer

scientific article

Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY).

scientific article

GLP-1 Receptor Agonist Treatment Increases Bone Formation and Prevents Bone Loss in Weight-Reduced Obese Women

scientific article published on 4 June 2015

GLP-1 Receptor Agonist Treatment in Morbid Obesity and Type 2 Diabetes Due to Pathogenic Homozygous Melanocortin-4 Receptor Mutation: A Case Report

scientific article published on 21 April 2020

GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study

article

GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia

scientific article

GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal

scientific article published on 30 October 2023

Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry

scientific article

Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study

scientific article

Genetic Susceptibility for Childhood BMI has no Impact on Weight Loss Following Lifestyle Intervention in Danish Children

scientific article published on 01 December 2018

Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function

scientific article published on 16 December 2016

Genetic analysis of the estrogen-related receptor α and studies of association with obesity and type 2 diabetes

article

Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data

scientific article

Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets

scientific article

Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study

scientific article

Genetic association analysis of LARS2 with type 2 diabetes

scientific article (publication date: 2010)

Genetic determinants of blood pressure traits are associated with carotid arterial thickening and plaque formation in patients with type 2 diabetes

scientific article published on 01 January 2019

Genetic determinants of both ethanol and acetaldehyde metabolism influence alcohol hypersensitivity and drinking behaviour among Scandinavians

scientific article

Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population

scientific article published on 26 February 2018

Genetic determinants of serum vitamin B12 and their relation to body mass index

scientific article published on 19 December 2016

Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4alpha, GCK and HNF-1alpha

article

Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels

scientific article published on 10 February 2017

Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function

scientific article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genetic insights into fetal growth and measures of glycaemic regulation and adiposity in adulthood: a family-based study ⬇️

Genetic investigations of sudden unexpected deaths in infancy using next-generation sequencing of 100 genes associated with cardiac diseases

scientific article published on 9 September 2015

Genetic predisposition to adiposity is associated with increased objectively assessed sedentary time in young children.

scientific article published on 26 September 2017

Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents

scientific article published on 22 July 2019

Genetic risk score of 46 type 2 diabetes risk variants associates with changes in plasma glucose and estimates of pancreatic β-cell function over 5 years of follow-up

scientific article published on 08 July 2013

Genetic risk scores for body fat distribution attenuate weight loss in women during dietary intervention

scientific article published on 16 November 2017

Genetic risk scores link body fat distribution with specific cardiometabolic profiles

scientific article published on 17 June 2016

Genetic variant SLC2A2 [corrected] Is associated with risk of cardiovascular disease – assessing the individual and cumulative effect of 46 type 2 diabetes related genetic variants

scientific article

Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes

scientific article published on February 2013

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on 18 April 2016

Genetic variants in promoters and coding regions of the muscle glycogen synthase and the insulin-responsive GLUT4 genes in NIDDM.

scientific article published in August 1994

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetics of Latent Autoimmune Diabetes in Adults

article

Genetics of Type 2 Diabetes: the Power of Isolated Populations

scientific article

Genetics of metabolic traits in Greenlanders: lessons from an isolated population

article

Genome wide association study identifies KCNMA1 contributing to human obesity

scientific article

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

scientific article published on 14 July 2016

Genome-Wide Interactions with Dairy Intake for Body Mass Index in Adults of European Descent

scientific article published on 21 September 2017

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

scientific article published in Nature Communications

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

scientific article published on 7 September 2022

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

scientific article published on 24 November 2015

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis

scholarly article by Johannes Waage et al published August 2018 in Nature Genetics

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

scientific article published on 24 January 2019

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

scientific article published on 28 January 2016

Genome-wide association studies of human adiposity: Zooming in on synapses

scientific article published on 28 September 2015

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

scientific journal article

Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test

scientific article published on 06 January 2021

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium

scientific article published on 09 July 2018

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

scientific article

Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype.

scientific article published on 20 June 2008

Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum.

scientific article

Glimepiride monotherapy versus combination of glimepiride and linagliptin therapy in patients with HNF1A-diabetes: a protocol for a randomised, double-blinded, placebo-controlled trial

scientific article published on 03 October 2018

Glucagon-Like Peptide-1 Is Associated With Systemic Inflammation in Pediatric Patients Treated With Hematopoietic Stem Cell Transplantation

scientific article published on 08 December 2021

Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon.

scientific article

Glucokinase diabetes in 103 families from a country-based study in the Czech Republic: geographically restricted distribution of two prevalent GCK mutations.

scientific article published in December 2010

Glucose ingestion causes cardiac repolarization disturbances in type 1 long QT syndrome patients and healthy subjects.

scientific article published on 8 April 2017

Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B.

scientific article published on 14 January 2011

Glucose-Dependent Insulinotropic Polypeptide Is Associated With Lower Low-Density Lipoprotein But Unhealthy Fat Distribution, Independent of Insulin: The ADDITION-PRO Study

scientific article published on 27 October 2015

Glucose-lowering effects and low risk of hypoglycemia in patients with maturity-onset diabetes of the young when treated with a GLP-1 receptor agonist: a double-blind, randomized, crossover trial

scientific article published in July 2014

Glyburide increases risk in patients with diabetes mellitus after emergent percutaneous intervention for myocardial infarction--a nationwide study

scientific article published on 24 August 2010

Greater glucagon-like peptide-1 responses to oral glucose are associated with lower central and peripheral blood pressures

scientific article published on 05 October 2019

Grey-box modelling of pharmacokinetic/pharmacodynamic systems.

scientific article published in October 2004

Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass.

scientific article published on 19 February 2013

Gut microbiota may have influence on glucose and lipid metabolism

scientific article

Gut microbiota may influence childhood and adolescent onset obesity ⬇️

scientific article

Habitual physical activity is associated with lower fasting and greater glucose-induced GLP-1 response in men

scientific article published on 01 December 2019

Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

scientific article

Heterogeneity in glucose response curves during an oral glucose tolerance test and associated cardiometabolic risk

scientific article

Heterozygous deletion at the RLN1 locus in a family with testicular germ cell cancer identified by integrating copy number variation data with phenome and interactome information

scientific article published on 22 June 2011

High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus

scientific article published on 27 April 2017

High heritability and genetic correlation of intravenous glucose- and tolbutamide-induced insulin secretion among non-diabetic family members of type 2 diabetic patients

scientific article published on 7 March 2014

Higher intake of fish and fat is associated with lower plasma s-adenosylhomocysteine: a cross-sectional study

scientific article published on 2 October 2017

Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1.

scientific article published on 7 August 2011

Homozygous carriers of the TCF7L2 rs7903146 T-allele show altered postprandial response in triglycerides and triglyceride-rich lipoproteins

scientific article published on 21 February 2017

Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression

scientific article

Human gut microbes impact host serum metabolome and insulin sensitivity

scientific article

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

scientific article published on 28 June 2019

Hypertension genetic risk score is associated with burden of coronary heart disease among patients referred for coronary angiography

scientific article published in PLoS ONE

IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies

scientific article

IRS1, KCNJ11, PPARgamma2 and HNF-1alpha: do amino acid polymorphisms in these candidate genes support a shared aetiology between type 1 and type 2 diabetes?

scientific article published on January 2006

Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

scientific article published on 6 July 2014

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

scientific article

Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus

scientific article

Identification of Mislabeled Samples and Sample Mix-ups in Genotype Data Using Barcode Genotypes

scientific article published in 2014

Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders

scientific article published on 24 June 2016

Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity

scientific article published on 01 March 1995

Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes

scientific article

Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity

scholarly article by Robina Khan Niazi et al published 15 November 2018 in BMC Medical Genetics

Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

scientific article published on 18 November 2020

Impact of IDDM2 on disease pathogenesis and progression in children with newly diagnosed type 1 diabetes: reduced insulin antibody titres and preserved beta cell function

scientific article published on 23 November 2005

Impact of PTBP1 rs11085226 on glucose-stimulated insulin release in adult Danes

scientific article published on 20 March 2015

Impact of a vegan diet on the human salivary microbiota.

scientific article

Impact of age, BMI and HbA1c levels on the genome-wide DNA methylation and mRNA expression patterns in human adipose tissue and identification of epigenetic biomarkers in blood

article published in 2015

Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

scientific article published on 21 June 2008

Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle

scientific article

Impact of size at birth and prematurity on adult anthropometry in 4744 middle-aged Danes - The Inter99 study

scientific article published in October 2010

Impact of the peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) Ala203Pro polymorphism on in vivo metabolism, PGC-1beta expression and fibre type composition in human skeletal muscle

scientific article published on 20 June 2007

Impact of two common polymorphisms in the PPARgamma gene on glucose tolerance and plasma insulin profiles in monozygotic and dizygotic twins: thrifty genotype, thrifty phenotype, or both?

scientific article published in January 2003

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article

Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study

scientific article published on 29 July 2008

Impaired fasting glucose and the metabolic profile in Danish children and adolescents with normal weight, overweight, or obesity.

scientific article published on 28 November 2017

Impaired meal stimulated glucagon-like peptide 2 response in ileal resected short bowel patients with intestinal failure.

scientific article

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism

Implications of central obesity-related variants in LYPLAL1, NRXN3, MSRA, and TFAP2B on quantitative metabolic traits in adult Danes

scientific article

Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes

scientific article published in PLoS ONE

Increased glucose-stimulated FGF21 response to oral glucose in obese nondiabetic subjects after Roux-en-Y gastric bypass.

scientific article published on 21 September 2016

Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes

scientific article published on 18 March 2011

Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years

scientific article published on 24 October 2016

Incretin and glucagon levels in adult offspring exposed to maternal diabetes in pregnancy

scientific article published on 17 March 2015

Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele

scientific article

Incretin effect and glucagon responses to oral and intravenous glucose in patients with maturity-onset diabetes of the young--type 2 and type 3.

scientific article

Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

scientific article

Insulin Resistance Is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation

scientific article published on 8 August 2016

Insulin analogues and severe hypoglycaemia in type 1 diabetes

scholarly article by P.L. Kristensen et al published April 2012 in Diabetes Research and Clinical Practice

Insulin analogues and severe hypoglycaemia in type 1 diabetes

scientific article published on 01 December 2011

Insulin resistance and impaired pancreatic β-cell function in adult offspring of women with diabetes in pregnancy

scientific article published on 24 June 2013

Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study

scientific article

Intake of macro- and micronutrients in Danish vegans

scientific article

Interaction between genetic predisposition to adiposity and dietary protein in relation to subsequent change in body weight and waist circumference

scientific article

Interaction between genetic predisposition to obesity and dietary calcium in relation to subsequent change in body weight and waist circumference

scientific article published on 5 February 2014

Interactions between genetic variants associated with adiposity traits and soft drinks in relation to longitudinal changes in body weight and waist circumference

scientific article published on 27 July 2016

Interactions of Lipid Genetic Risk Scores With Estimates of Metabolic Health in a Danish Population

scientific article published on 24 February 2015

Intrafamilial Variability of Early-Onset Diabetes due to an INS Mutation

scientific article

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

scientific article

KCNQ1 long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia

scientific article

LMNA rs4641 and the muscle lamin A and C isoforms in twins--metabolic implications and transcriptional regulation

scientific article published on 25 May 2010

Lack of association between PKLR rs3020781 and NOS1AP rs7538490 and type 2 diabetes, overweight, obesity and related metabolic phenotypes in a Danish large-scale study: case-control studies and analyses of quantitative traits

scientific article

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

scientific article published on 12 July 2017

Large-scale study of the ?232C�>�G polymorphism of PCK1 in Type�2 diabetes

Lens fluorescence in relation to glucose tolerance and genetic predisposition to type 2 diabetes mellitus in a population-based study

scientific article published in September 2006

Lessons from whole-exome sequencing in MODYX families

scholarly article by Petra Dusatkova et al published June 2014 in Diabetes Research and Clinical Practice

Levels of the inflammation marker YKL-40 in young adults exposed to intrauterine hyperglycemia

scientific article

Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic

scientific article published on 20 April 2022

Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining

scientific article published on 10 December 2019

Long-term high-physiological-dose growth hormone reduces intra-abdominal fat in HIV-infected patients with a neutral effect on glucose metabolism.

scientific article published on 8 December 2009

Long-term prevention of diabetic nephropathy: an audit

scientific article published on 03 April 2008

Long-term use of proton pump inhibitors, dose-response relationship and associated risk of ischemic stroke and myocardial infarction.

scientific article published on 12 October 2017

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

scientific article

Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

scientific article

Low birthweight and premature birth are both associated with type 2 diabetes in a random sample of middle-aged Danes.

scientific article published on 22 September 2010

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

Low-grade inflammation in young adults exposed to intrauterine hyperglycemia ⬇️

scientific article published on May 21, 2012

MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification

scientific article published on 24 January 2014

MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

scientific article

Major rapid weight loss induces changes in cardiac repolarization

scientific article published on 10 February 2016

Many sequence variants affecting diversity of adult human height

scientific article published in May 2008

Maternal and fetal genetic contribution to gestational weight gain.

scientific article published on 9 October 2017

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Maturity-Onset Diabetes of the Young Identified Among Algerian Probands with Early-Onset Diabetes

scientific article published on 08 December 2020

Maturity-onset diabetes of the young with end-stage nephropathy: a new indication for simultaneous pancreas and kidney transplantation?

scientific article published in April 2004

Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test

scientific article published on 16 September 2011

Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass

scientific article published on 27 April 2012

Melanocortin 4 receptor mutations in obese Czech children: studies of prevalence, phenotype development, weight reduction response, and functional analysis

scientific article published on 19 June 2007

Mendelian randomisation study of the associations of vitamin B12 and folate genetic risk scores with blood pressure and fasting serum lipid levels in three Danish population-based studies.

scientific article published on 24 February 2016

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

scientific article published on 07 May 2020

Mendelian randomization studies do not support a causal role for reduced circulating adiponectin levels in insulin resistance and type 2 diabetes

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis of exome array data identifies six novel genetic loci for lung function

scientific article published on 12 January 2018

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

scientific article

Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes

scientific article

Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits.

scientific article

Metformin treatment is associated with a low risk of mortality in diabetic patients with heart failure: a retrospective nationwide cohort study

scientific article published on 14 September 2010

Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration

scientific article published on 19 October 2011

Microbiome and metabolome features of the cardiometabolic disease spectrum

scientific article published on 17 February 2022

Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle

scientific article published on 30 December 2015

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

scientific article published in Nature Communications

Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity

article

Mutation analysis of the preproghrelin gene: no association with obesity and type 2 diabetes

scientific article published in May 2005

Mutations in HNF1A result in marked alterations of plasma glycan profile

scientific article published on 28 December 2012

N-terminally and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor

scientific article published on 17 November 2015

Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance: the Inter99 study

scientific article published on 03 December 2008

Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome.

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

scientific article published on 2 December 2012

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

No detectable effect of a type 2 diabetes-associated TCF7L2 genotype on the incretin effect

scientific article published on 01 November 2020

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

scientific article published on 13 March 2012

Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes

scientific article

Noninvasive proteomic biomarkers for alcohol-related liver disease

scientific article published in 2022

Novel Variants in the Putative Peroxisome Proliferator-activated Receptor γ Promoter and Relationships with Obesity in Men

scholarly article by Thomas M Larsen et al published June 2005 in Obesity

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

scientific article published on 12 October 2020

Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios ⬇️

scientific article

Numerous Brugada syndrome-associated genetic variants have no effect on J-point elevation, syncope susceptibility, malignant cardiac arrhythmia, and all-cause mortality

scientific article published on 6 October 2016

Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans.

scientific article published on 6 December 2015

Obesity is associated with vitamin D deficiency in Danish children and adolescents

scientific article published on 4 December 2017

Obesity treatment effect in Danish children and adolescents carrying Melanocortin-4 Receptor mutations

scientific article published on 13 September 2020

Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial

scientific article published on 12 January 2017

One-carbon metabolism markers are associated with cardiometabolic risk factors.

scientific article published on 31 January 2018

Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes.

scientific article published on September 2010

P1356A nationwide study: Differences in use of neurological prognostication procedures in out-of-hospital cardiac arrest patients in intensive care units from 2004-2013

P2740Use of dialysis in out-of-hospital cardiac arrest patients in Danish intensive care units from 2004-2013 and implications for outcome

scholarly article by M. Winther-Jensen et al published 1 August 2017 in European Heart Journal

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016

PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites

scientific article published on 28 February 2005

PPARG Pro12Ala Ala carriers exhibit greater improvements in peripheral insulin sensitivity in response to 12 weeks of aerobic exercise training

scientific article published on 10 May 2019

Patients With Long-QT Syndrome Caused by Impaired hERG-Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated With Reactive Hypoglycemia

scientific article

Pharmacogenetics and individual responses to treatment of hyperglycemia in type 2 diabetes

scientific article published on 14 July 2015

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

scientific article

Physiologic characterization of type 2 diabetes-related loci

scientific article

Plasma Alkylresorcinols Reflect Gluten Intake and Distinguish between Gluten-Rich and Gluten-Poor Diets in a Population at Risk of Metabolic Syndrome

scientific article published on 14 September 2016

Plasma follistatin is elevated in patients with type 2 diabetes: relationship to hyperglycemia, hyperinsulinemia, and systemic low-grade inflammation

scientific article published in September 2013

Pleiotropic genes for metabolic syndrome and inflammation

scientific article

Polygenic predisposition to breast cancer and the risk of coronary artery disease

scientific article published on 24 May 2019

Polymorphisms in AHI1 are not associated with type 2 diabetes or related phenotypes in Danes: non-replication of a genome-wide association result

article by J. Holmkvist et al published 29 January 2008 in Diabetologia

Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy

scientific article published on 02 August 2007

Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes

scientific article

Ponderal index at birth associates with later risk of gestational diabetes mellitus.

scientific article published on 17 June 2017

Population-based studies of relationships between dietary acidity load, insulin resistance and incident diabetes in Danes

scientific article published on 06 October 2018

Post-load glucose subgroups and associated metabolic traits in individuals with type 2 diabetes: An IMI-DIRECT study

scientific article published on 30 November 2020

Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young

scientific article published on 7 May 2015

Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts

scientific article published on 19 June 2020

Predictors of weight loss after bariatric surgery-a cross-disciplinary approach combining physiological, social, and psychological measures

scientific article published on 23 April 2020

Pregnancy-associated plasma protein A in a large cohort of Type 1 diabetic patients with and without diabetic nephropathy—a prospective follow-up study

scientific article published on 29 October 2007

Processes Underlying Glycemic Deterioration in Type 2 Diabetes: An IMI DIRECT Study

scientific article published on 15 December 2020

Prognostic impact of carboxylesterase 1 gene variants in patients with congestive heart failure treated with angiotensin-converting enzyme inhibitors

scientific article published on 12 January 2016

Prospective studies exploring the possible impact of an ID3 polymorphism on changes in obesity measures

scientific article published on 14 February 2018

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.

scientific article published on 30 May 2018

Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

scientific article published on 25 July 2019

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rare genetic variants previously associated with congenital forms of long QT syndrome have little or no effect on the QT interval

scientific article

Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes

scientific article

Reappraisal of variants previously linked with sudden infant death syndrome: results from three population-based cohorts

scientific article published on 01 May 2019

Reassessment of the putative role of BLK-p.A71T loss-of-function mutation in MODY and type 2 diabetes.

scientific article published on 6 December 2012

Recessive Genome-Wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes

scientific article published on 01 March 2022

Recovery of gut microbiota of healthy adults following antibiotic exposure

scientific article published on 22 October 2018

Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes

scientific article

Reference intervals for C-peptide and insulin derived from a general adult Danish population

scientific article published on 15 December 2016

Reference values for fasting serum concentrations of thyroid-stimulating hormone and thyroid hormones in healthy Danish/North-European white children and adolescents

scientific article published on 01 February 2019

Reference values for fasting serum resistin in healthy children and adolescents.

scientific article published on 6 April 2017

Reference values for leptin/adiponectin ratio in healthy children and adolescents

scientific article published on 06 March 2019

Reference values for serum leptin in healthy non-obese children and adolescents

scientific article published on 9 August 2016

Reference values for serum total adiponectin in healthy non-obese children and adolescents

scientific article published on 10 July 2015

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution

article

Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people

scientific article published on 28 November 2006

Renoprotective effects of angiotensin II receptor blockade in type 1 diabetic patients with diabetic nephropathy

scientific article published on 01 February 2000

Replication and meta-analysis of common variants identifies a genome-wide significant locus in migraine.

scientific article published on 7 January 2013

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

Response to Comment on Færch et al. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study. Diabetes 2015;64:2513–2525

Richness of human gut microbiome correlates with metabolic markers

scientific article (publication date: 29 August 2013)

Risk of myocardial infarction and death associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) among healthy individuals: a nationwide cohort study

scientific article published on 5 November 2008

Risk of thromboembolism and fatal stroke in patients with psoriasis and nonvalvular atrial fibrillation: a Danish nationwide cohort study

scientific article published on 13 June 2014

Role of fasting duration and weekday in incretin and glucose regulation

scientific article published on 01 March 2020

Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function

scientific article

Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota

scientific article

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

article

Scanning the available Dictyostelium discoideum proteome for O-linked GlcNAc glycosylation sites using neural networks.

scientific article published in October 1999

Screening of 31 genes involved in monogenic forms of obesity in 23 Pakistani probands with early-onset childhood obesity: a case report

scientific article published on 05 September 2019

Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity.

scientific article

Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes

scientific article

Self-Reported Versus Accelerometer-Assessed Daily Physical Activity in Childhood Obesity Treatment.

scientific article published on January 2017

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Sequencing and de novo assembly of 150 genomes from Denmark as a population reference

scientific article published in Nature

Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants

scientific article published on 15 August 2019

Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility.

scientific article

Short-term Administration of Glucagon-like Peptide-2. Effects on Bone Mineral Density and Markers of Bone Turnover in Short-Bowel Patients with No Colon

scientific article published on 01 April 2002

Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

scientific article published on 01 June 2020

Solute carrier family 2 member 1 is involved in the development of nonalcoholic fatty liver disease

scientific article

Spatial QRS-T angle variants for prediction of all-cause mortality

scientific article published on 22 May 2018

Species-specific action of (Pro3)GIP - a full agonist at human GIP receptors, but a partial agonist and competitive antagonist at rat and mouse GIP receptors

scientific article published on 11 September 2015

Specific gut microbiota features and metabolic markers in postmenopausal women with obesity

scientific article published on 15 June 2015

Statin therapy is associated with lower prevalence of gut microbiota dysbiosis

scientific article published on 06 May 2020

Studies of CTNNBL1 and FDFT1 variants and measures of obesity: analyses of quantitative traits and case-control studies in 18,014 Danes

scientific article

Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes

scientific article

Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes

scientific article published on 31 March 2010

Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes

scientific article

Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites

scientific article published on 2 August 2007

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies

scientific article published on 7 September 2007

Studies of associations between the Arg389Gly polymorphism of the beta1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects.

scientific article

Studies of metabolic phenotypic correlates of 15 obesity associated gene variants

scientific article

Studies of the association of Arg72Pro of tumor suppressor protein p53 with type 2 diabetes in a combined analysis of 55,521 Europeans

scientific article

Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes.

scientific article

Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects.

scientific article published on 13 January 2007

Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

scientific article published on 31 October 2006

Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects

scientific article published on 25 July 2006

Studies of variations of the cyclin-dependent kinase inhibitor 1C and the cyclin-dependent kinase 4 genes in relation to type 2 diabetes mellitus and related quantitative traits

scientific article published on 9 April 2005

Subclinical Hypothyroidism in Danish Lean and Obese Children and Adolescents.

scientific article published on 09 September 2016

TFAP2B influences the effect of dietary fat on weight loss under energy restriction

scientific article

The Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene contributes to the interindividual variation in serum C-peptide response during an oral glucose tolerance test: evidence from studies of 231 glucose-tolerant first degree relativ

article

The BIGTT test: a novel test for simultaneous measurement of pancreatic beta-cell function, insulin sensitivity, and glucose tolerance

scientific article published in February 2007

The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

scientific article published on 14 May 2013

The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit

scientific article published on 30 November 2016

The FOXO3A rs2802292 G-allele associates with improved peripheral and hepatic insulin sensitivity and increased skeletal muscle-FOXO3A mRNA expression in twins

scientific article published on 29 September 2010

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

scientific article

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study

scientific article published in November 2006

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation

scientific article (publication date: 2012)

The PPARγ2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy

The Polygenic and Monogenic Basis of Blood Traits and Diseases

scientific article published on 01 September 2020

The Role of the Gut Microbiota in Childhood Obesity

scientific article published on 8 April 2016

The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.

scientific article published on 14 March 2009

The antidepressant-like effect of probiotics and their faecal abundance may be modulated by the cohabiting gut microbiota in rats

scientific article published on 02 November 2018

The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample

scientific article

The association of alcohol and alcohol metabolizing gene variants with diabetes and coronary heart disease risk factors in a white population

scientific article

The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge

scientific article (publication date: 2011)

The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study

scientific article published on 7 March 2008

The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders

scientific article published on 24 January 2020

The effect of FOXA2 rs1209523 on glucose-related phenotypes and risk of type 2 diabetes in Danish individuals

scientific article

The effect of GWAS identified BMI loci on changes in body weight among middle-aged Danes during a five-year period.

scientific article published on 19 August 2013

The effect of PCSK1 variants on waist, waist-hip ratio and glucose metabolism is modified by sex and glucose tolerance status

scientific article (publication date: 2011)

The effect of diabetes and the common diabetogenic TBC1D4 p.Arg684Ter variant on cardiovascular risk in Inuit in Greenland

scientific article published on 16 December 2020

The effect of diaries written by relatives for intensive care patients on posttraumatic stress (DRIP study): protocol for a randomized controlled trial and mixed methods study

scientific article published on 16 August 2018

The effect of drinking water pH on the human gut microbiota and glucose regulation: results of a randomized controlled cross-over intervention

scientific article published in Scientific Reports

The effect of impaired glucose metabolism on weight loss in multidisciplinary childhood obesity treatment.

scientific article published on 20 November 2017

The effect of smoking on the urinary excretion of 8-oxodG and 8-oxoGuo in patients with type 2 diabetes

The effect of strength and endurance training on insulin sensitivity and fat distribution in human immunodeficiency virus-infected patients with lipodystrophy

scientific article published on 15 July 2008

The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1alpha gene on estimates of the pancreatic beta-cell function in Caucasian glucose-tolerant first-degree relatives of type 2 diabetic patients

article

The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity

scientific article published on 02 October 2019

The frequent UCP2 -866G>A polymorphism protects against insulin resistance and is associated with obesity: a study of obesity and related metabolic traits among 17 636 Danes.

scientific article published on 21 February 2012

The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites

article

The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes

scientific article published on 22 February 2005

The genetic abnormality in the beta cell determines the response to an oral glucose load

scientific article published in March 2002

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The gut microbiome in cardio-metabolic health.

scientific article

The iPSYCH2012 case-cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders.

scientific article

The influence of parental history of diabetes and offspring birthweight on offspring glucose metabolism in adulthood

The influence of transmitted and non-transmitted parental BMI-associated alleles on the risk of overweight in childhood

scientific article published on 16 March 2020

The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load

scientific article

The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype

scientific article published in October 2003

The prevalence of metabolic syndrome in Danish patients with HIV infection: the effect of antiretroviral therapy

scientific article

The prevalence of the metabolic syndrome in a danish population of women with previous gestational diabetes mellitus is three-fold higher than in the general population

scientific article

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

article

The type 2 diabetes risk allele of TMEM154-rs6813195 associates with decreased beta cell function in a study of 6,486 Danes

scientific article

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

scientific article published on 01 September 2020

Transcriptional interactions suggest niche segregation among microorganisms in the human gut.

scientific article

Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss.

scientific article

Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB.

scientific article published on 21 November 2017

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article

Two variants on chromosome 17 confer prostate cancer risk and the one in TCF2 protects against type 2 diabetes

article

Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.

scientific article

Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort

scientific article published in March 2013

Ultraviolet Radiation Exposure and Risk of Malignant Lymphomas

Uncovering the genetic history of the present-day Greenlandic population. ⬇️

scientific article

Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts

scientific article

Urinary nucleic acid oxidation product levels show differential associations with pharmacological treatment in patients with type 2 diabetes

scientific article published on 04 June 2019

Validation of a multi-marker model for the prediction of incident type 2 diabetes mellitus: combined results of the Inter99 and Botnia studies

scientific article published on 4 November 2011

Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies

scientific article

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

scientific article

Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

scientific article published on 26 April 2010

Variants in the 5′ region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects

article

Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population

scientific article published on 22 January 2014

Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: Studies in 6018 whites

article

Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes

article

Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites.

scientific article published in December 2004

Variation in the peroxisome proliferator-activated receptor delta gene in relation to common metabolic traits in 7,495 middle-aged white people

scientific article published on 13 April 2007

Variation of the McKusick-Kaufman Gene and Studies of Relationships with Common Forms of Obesity

article

Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes.

scientific article published on 11 January 2005

Vejle Diabetes Biobank - a resource for studies of the etiologies of diabetes and its comorbidities

scientific article published on 21 October 2016

Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels

What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications?

scientific article

Whole blood co-expression modules associate with metabolic traits and type 2 diabetes: an IMI-DIRECT study

scientific article published on 01 December 2020

Whole-Exome Sequencing of 2,000 Danish Individuals and the Role of Rare Coding Variants in Type 2 Diabetes

Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes

scientific article

[Maturity-onset diabetes of the young--MODY. Molecular-genetic, pathophysiological and clinical characteristics]

scientific article published on 01 April 2002

[Successful treatment of KCNJ11 neonatal diabetes without insulin] ⬇️

scientific article published on 01 November 2018

[The genome and diabetes] ⬇️

scientific article published on 01 November 2014

Paulina is supported by:

About Paulina

Help