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List of works by Konstantin Strauch

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article

52 Genetic Loci Influencing Myocardial Mass

scientific article

A European study on the genetics of mite sensitization

article

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

scientific article published on 24 March 2017

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A comparison of different linkage statistics in small to moderate sized pedigrees with complex diseases ⬇️

scientific article published on August 6, 2012

A genome-wide association meta-analysis on apolipoprotein A-IV concentrations

scientific article published on 12 July 2016

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms

scientific article published on 16 May 2017

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A new susceptibility locus for bipolar affective disorder in PAR1 on Xp22.3/Yp11.3

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A regulatory variant in CCR6 is associated with susceptibility to antitopoisomerase-positive systemic sclerosis

scientific article published on December 2013

A systematic evaluation of short tandem repeats in lipid candidate genes: riding on the SNP-wave

scientific article

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

scientific article published on 23 February 2015

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

Analysis with the exome array identifies multiple new independent variants in lipid loci

scientific article published on 27 July 2016

Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium

scientific article

Anxiety Associated Increased CpG Methylation In The Promoter of Asb1: A Translational Approach Evidenced By Epidemiological And Clinical Studies And A Murine Model

scientific article published on 25 May 2017

Assessing absolute changes in breast cancer risk due to modifiable risk factors

scientific article published on 27 May 2015

Association study of mitochondrial genetic polymorphisms in asthmatic children

scientific article

Breast cancer risk assessment across the risk continuum: genetic and nongenetic risk factors contributing to differential model performance

scientific article

Burden analysis of rare microdeletions suggests a strong impact of neurodevelopmental genes in genetic generalised epilepsies

scientific article

Cell Specific eQTL Analysis without Sorting Cells

scientific article published on 8 May 2015

Cell specific eQTL analysis without sorting cells

Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies

scholarly article published 11 February 2018

Chronic low back pain patient groups in primary care--a cross sectional cluster analysis

scientific article

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

scientific article published on 2 March 2016

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Connecting genetic risk to disease end points through the human blood plasma proteome

scientific article published on 27 February 2017

Connecting genetic risk to disease endpoints through the human blood plasma proteome

Correction: Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study

scientific article published on 14 September 2017

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

scientific article published on 26 May 2017

Corrigendum: Rare coding variants and X-linked loci associated with age at menarche

scientific article published on 17 December 2015

Deciphering the 8q24.21 association for glioma

scientific article published on 11 February 2013

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Development and application of genomic control methods for genome-wide association studies using non-additive models

scientific article

Differences between patients with chronic widespread pain and local chronic low back pain in primary care--a comparative cross-sectional analysis

scientific article

Differential associations between diet and prediabetes or diabetes in the KORA FF4 study

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study

scientific article

Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes

scientific article published on 5 August 2015

Efficient two-trait-locus linkage analysis through program optimization and parallelization: application to hypercholesterolemia

scientific article

Epigenetic Signatures at AQP3 and SOCS3 Engage in Low-Grade Inflammation across Different Tissues

scientific article

Epigenetics meets metabolomics: an epigenome-wide association study with blood serum metabolic traits

scientific article published on 06 September 2013

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

scientific article published on 21 December 2016

Erratum: Connecting genetic risk to disease end points through the human blood plasma proteome

scientific article published on 11 April 2017

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk

scientific article published on 2 August 2017

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Estimation of Trait-Model Parameters in a MOD Score Linkage Analysis

scientific article

Even Worse - Risk Factors and Protective Factors for Transition from Chronic Localized Low Back Pain to Chronic Widespread Pain in General Practice: A Cohort Study

scientific article

Evidence for the involvement of genetic variation in the oxytocin receptor gene (OXTR) in the etiology of autistic disorders on high-functioning level

scientific article

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 06 June 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling

scientific article

Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy

scientific article

Explorative two-locus linkage analysis suggests a multiplicative interaction between the 7q32 and 16p13 myoclonic seizures-related photosensitivity loci

article

Expression of the nuclear oncogene Ski in patients with acute myeloid leukemia treated with all-trans retinoic acid

scientific article published on 27 May 2008

Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts

scientific article published on 15 October 2015

Fast linkage analysis with MOD scores using algebraic calculation

scientific article published in January 2014

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Genetic Factors Explain a Major Fraction of the 50% Lower Lipoprotein(a) Concentrations in Finns

scientific article published on 22 March 2018

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

scientific article published on 11 September 2020

Genetic analysis of phenotypes derived from longitudinal data: Presentation Group 1 of Genetic Analysis Workshop 13.

scientific article

Genetic dissection of photosensitivity and its relation to idiopathic generalized epilepsy

scientific article

Genetic evidence for PLASMINOGEN as a shared genetic risk factor of coronary artery disease and periodontitis

scientific article published on 2 December 2014

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genetic insights into biological mechanisms governing human ovarian ageing

scientific article

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes

scientific article

Genetic variants of lipase activity in chronic pancreatitis

scientific article

Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms

scientific article

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

scientific article published in PLoS ONE

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-Wide Analysis of DNA Methylation and Fine Particulate Matter Air Pollution in Three Study Populations: KORA F3, KORA F4, and the Normative Aging Study

scientific article published on 05 January 2016

Genome-Wide Association Study on Immunoglobulin G Glycosylation Patterns

scientific article published on 26 February 2018

Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality

scientific article published on 9 September 2015

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci

scientific article published on 04 April 2017

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis

scientific article

Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels

scientific article

Genome-wide association study in essential tremor identifies three new loci

scientific article published on 20 October 2016

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

scientific article

Genome-wide linkage analysis of congenital heart defects using MOD score analysis identifies two novel loci ⬇️

scientific article published on May 24, 2013

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide methylation data mirror ancestry information

scientific article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genomewide scan and fine-mapping linkage studies in four European samples with bipolar affective disorder suggest a new susceptibility locus on chromosome 1p35-p36 and provides further evidence of loci on chromosome 4q31 and 6q24.

scientific article

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

scientific article published on 23 September 2016

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

scientific article published on 24 April 2017

Haplotype analysis of the engrailed-2 gene in young-onset Parkinson's disease

scientific article published on 6 March 2009

High-frequency jet ventilation for complete target immobilization and reduction of planning target volume in stereotactic high single-dose irradiation of stage I non-small cell lung cancer and lung metastases

scientific article published on 10 November 2009

How to model a complex trait. 1. General considerations and suggestions

scientific article published on January 2003

Identification of Immune-Relevant Factors Conferring Sarcoidosis Genetic Risk

scientific article

Identification of probable genotyping errors by consideration of haplotypes

article

Immunochip analysis identifies association of the RAD50/IL13 region with human longevity

scientific article published on 22 March 2016

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

Implementation of a guideline for low back pain management in primary care: a cost-effectiveness analysis

scientific article

Inferential testing for linkage with GENEHUNTER-MODSCORE: The impact of the pedigree structure on the null distribution of multipoint MOD scores

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

scientific article

Investigation of parent-of-origin effect in comitant strabismus using MOD score analysis

scientific article published on 09 June 2009

LCN2 and TIMP1 as Potential Serum Markers for the Early Detection of Familial Pancreatic Cancer

scientific article

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

scientific article published in December 2015

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Linkage analysis of alcohol dependence using MOD scores

scientific article published on 30 December 2005

Lipoprotein (a) concentrations, apolipoprotein (a) phenotypes, and peripheral arterial disease in three independent cohorts

scientific article

Low back pain in primary care: costs of care and prediction of future health care utilization

scientific article

Low back pain patient subgroups in primary care: pain characteristics, psychosocial determinants, and health care utilization

scientific article

Mapping the genetic architecture of gene regulation in whole blood

scientific article

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

scientific article published on 10 May 2019

Meta-Analysis of Genome-Wide Association Studies and Network Analysis-Based Integration with Gene Expression Data Identify New Suggestive Loci and Unravel a Wnt-Centric Network Associated with Dupuytren's Disease

scientific article

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

scientific article published on 30 October 2020

Metabolite profiling reveals new insights into the regulation of serum urate in humans

scientific article published on 20 July 2013

Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues

scientific article published on 12 September 2016

MicroRNA-196a and -196b as Potential Biomarkers for the Early Detection of Familial Pancreatic Cancer

scientific article published on 21 June 2014

Mitochondrial GWA Analysis of Lipid Profile Identifies Genetic Variants to Be Associated with HDL Cholesterol and Triglyceride Levels

scientific article published on 6 May 2015

Mitochondrial genetic variants identified to be associated with BMI in adults

scientific article published in 2014

Modulation of genetic associations with serum urate levels by body-mass-index in humans

scientific article

Molecular Characterization of the NLRC4 Expression in Relation to Interleukin-18 Levels

scientific article

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

scientific article published in Nature Communications

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

Multilocus haplotype analyses reveal association between 5 novel IL-15 polymorphisms and asthma

scientific article published in May 2004

Multi‐phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations

scientific article published in 2022

Mutation in the ARH gene and a chromosome 13q locus influence cholesterol levels in a new form of digenic-recessive familial hypercholesterolemia

scientific article (publication date: 17 May 2002)

NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality

scientific article published on 30 March 2017

Network based conditional genome wide association analysis of human metabolomics

Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway

scientific article published on 14 November 2017

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

No association between the ALDH2 promoter polymorphism rs886205, alcohol dependence, and risky alcohol consumption in a German population

scientific article published in February 2015

No evidence for involvement of genetic variants in the X-linked neuroligin genes NLGN3 and NLGN4X in probands with autism spectrum disorder on high functioning level

scientific article

Nonadditive Effects of Genes in Human Metabolomics

scientific article published on 14 May 2015

Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index

scientific article

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Novel genetic associations with serum level metabolites identified by phenotype set enrichment analyses

scientific article

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation

scientific article published on 17 June 2016

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Parameter estimation and quantitative parametric linkage analysis with GENEHUNTER-QMOD.

scientific article published on 19 August 2012

Parent-of-origin, imprinting, mitochondrial, and X-linked effects in traits related to alcohol dependence: presentation Group 18 of Genetic Analysis Workshop 14.

scientific article published in January 2005

Practical problems with clinical guidelines for breast cancer prevention based on remaining lifetime risk

scientific article

Projections of cancer incidence and cancer-related deaths in Germany by 2020 and 2030.

scientific article published on 29 June 2016

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Psychological risk and protective factors for disability in chronic low back pain - a longitudinal analysis in primary care

scientific article

Publisher Correction: Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway

scientific article published on 13 February 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Quantitative trait linkage analysis of longitudinal change in body weight

scientific article published on 31 December 2003

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

scientific article

Rare coding variants and X-linked loci associated with age at menarche

scientific article

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Risk factors of neonatal respiratory distress following vaginal delivery and caesarean section in the German population

scientific article published in January 2009

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

scientific article published on 5 December 2016

Safety and Efficacy of Botulinum Toxin to Preserve Gland Function after Radiotherapy in Patients with Head and Neck Cancer: A Prospective, Randomized, Placebo-Controlled, Double-Blinded Phase I Clinical Trial

scientific article

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

scientific article published on 30 October 2017

Stereotactic, high single-dose irradiation of stage I non-small cell lung cancer (NSCLC) using four-dimensional CT scans for treatment planning

scientific article published on 28 November 2007

Study protocol: Transition from localized low back pain to chronic widespread pain in general practice: identification of risk factors, preventive factors and key elements for treatment--a cohort study

scientific article

Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array

scientific article published on 26 October 2015

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease ⬇️

scientific article published on February 2017

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

Telomere length in circulating leukocytes is associated with lung function and disease.

scientific article published on 5 December 2013

The Combination of MiRNA-196b, LCN2, and TIMP1 is a Potential Set of Circulating Biomarkers for Screening Individuals at Risk for Familial Pancreatic Cancer

article published in 2018

The Human Blood Metabolome-Transcriptome Interface

scientific article published on 18 June 2015

The Pharmacogenetic Footprint of ACE Inhibition: A Population-Based Metabolomics Study

scientific article

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus

Tobacco smoking leads to extensive genome-wide changes in DNA methylation

scientific article

pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms

scientific article published on 29 September 2017

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