Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Author/s

author: Georgia Chenevix-Trench, Kamila Czene, Angela Cox, Hiltrud Brauch, Barbara Burwinkel, Ute Hamann, Jenny Chang-Claude, Najaf Amin, Ozren Polašek, Caroline Hayward, Eric Boerwinkle, Luigi Ferrucci, Immaculata De Vivo, Gonneke Willemsen, Unnur Þorsteinsdóttir, Jouke-Jan Hottenga, Fernando Rivadeneira, Claudia Langenberg, Martina Müller-Nurasyid, Daniela Toniolo, Marina Ciullo, Vilmundur Gudnason, Hermann Brenner, André Uitterlinden, Andres Metspalu, Tõnu Esko, Alexander Teumer, Reedik Mägi, Massimo Mangino, Sandosh Padmanabhan, Tatijana Zemunik, Heli Nevanlinna, Patrick Sulem, Anna González-Neira, Antonietta Robino, Christian Gieger, Albert Hofman, Kári Stefánsson, Bruce M. Psaty, Serena Sanna, Laufey Tryggvadottir, Diether Lambrechts, Henry Völzke, Georg Homuth, Charles Kooperberg, David Schlessinger, Cornelia M. van Duijn, Hoda Anton-Culver, Laura Crisponi, Veli-Matti Kosma, Arto Mannermaa, Pascal Guénel, Kyriaki Michailidou, Dieter Flesch-Janys, Katri Pylkäs, Thérèse Truong, Montserrat García-Closas, Anne-Lise Børresen-Dale, Drakoulis Yannoukakos, Robert Winqvist, Thilo Dörk, Vessela Kristensen, Peter Devilee, Paolo Peterlongo, Igor Rudan, Eleonora Porcu, Børge G. Nordestgaard, Dragana Vuckovic, Ailith Pirie, Thibaud S Boutin, Jonathan Marten, Ilaria Gandin, Daniela Ruggiero, Diego Vozzi, Giorgia Girotto, Teresa Nutile, Jessica D. Faul, Felix R. Day, Anna Murray, Lili Milani, Lynne J Hocking, Minouk J Schoemaker, Ivana Kolcic, Isabel dos Santos Silva, David Karasik, Alanna Morrison, Jennifer A Smith, Jingmei Li, Kathryn L. Lunetta, Marjanka K Schmidt, Lude Franke, Paolo Radice, Albert V. Smith, Alison Dunning, Grant W. Montgomery, Melissa C. Southey, Anna Jakubowska, Jerome I Rotter, Ellen W Demerath, Frank B. Hu, Leslie Bernstein, Anthony Swerdlow, Stephen Chanock, Paul D P Pharoah, Samuel E Jones, Jan Lubiński, Tamara B. Harris, Julian Peto, Graham Giles, Per Hall, Alfons Meindl, Rita Schmutzler, Douglas F. Easton, Fergus J. Couch, Peter A. Fasching, John Hopper, Roger L. Milne, Keith Humphreys, Jacques Simard, Irene L Andrulis, Nicholas J. Wareham, David J. Porteous, Sven Bergmann, Dorret I. Boomsma, Yongmei Liu, Wei Zheng, Jonine Figueroa, Sara Margolin, Matthias W. Beckmann, Stig Egil Bojesen, Joe Dennis, Volker Arndt, Anja Rudolph, Javier Benitez, Amanda Ewart Toland, Caroline Seynaeve, Christopher A. Haiman, Carl Blomqvist, Brian E. Henderson, Daníel F. Guðbjartsson, Ian Tomlinson, Maartje J. Hooning, David J. Hunter, Natalia V. Bogdanova, Elinor J. Sawyer, Konstantin Strauch, Julia A. Knight, Janet E. Olson, Thomas Brüning, Julie E. Buring, Sharon L R Kardia, Antonis C Antoniou, Paul Ridker, Nora Franceschini, Daniel I Chasman, Evelin Mihailov, Lynda M Rose, Kent D Taylor, Mark O Goodarzi, Patrick Neven, James F. Wilson, Ulrike Peters, Anne B. Newman, Harry Campbell, Laura M Yerges-Armstrong, Tim Spector, Toshiko Tanaka, Jennifer A. Brody, Rosalind Eeles, Ken K Ong, Benjamin M. Neale, Yen-Chu Chen, Mark P Goldberg, Hilary K Finucane, Alkes Price, Nick Martin, Bruce H Wolffenbuttel, Behrooz Z. Alizadeh, Jenny A Visser, Joanne M Murabito, Deborah Thompson, Hatef Darabi, Manjeet K Bolla, Alicia Beeghly-Fadiel, Maria Kabisch, Archie I Campbell, Natalia Pervyakova, Lisette Stolk, Brendan Bulik-Sullivan, Cathy E Elks, Elisabeth Altmaier, Jennifer E Huffman, Margaux F Keller, Patrick McArdle, Ursula M Schick, Michela Traglia, Tanguy Corre, Caterina M Barbieri, Suzette J Bielinski, Ross Chapman, Andrea D Coviello, Xiuqing Guo, Jinyan Huang, Jennifer Kriebel, Judith Manz, Corrado Masciullo, Astrid Petersmann, Nicola Pirastu, Giorgio Pistis, Leslie J Raffel, Sala Cinzia Felicita, Rossella Sorice, Doris Stöckl, Barbara McKnight, Katherine S Ruth, Gonçalo Abecasis, Robert A Scott, Michael G. Marmot, Melissa N Garcia, David Weir, Eva Albrecht, Peter Kraft, Sara Lindstroem, Alice M. Arnold, Andrew D. Johnson, John R. B. Perry

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