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List of works by E. Shyong Tai

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

scientific article published on 27 April 2018

A Healthy Asian A Posteriori Dietary Pattern Correlates with A Priori Dietary Patterns and Is Associated with Cardiovascular Disease Risk Factors in a Multiethnic Asian Population

scientific article published on 01 April 2018

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

scientific article published on 24 March 2017

A Randomized Controlled Trial to Evaluate the Effects of a Smartphone Application-Based Lifestyle Coaching Program on Gestational Weight Gain, Glycemic Control, Maternal, and Neonatal Outcomes in Women With Gestational Diabetes Mellitus: The SMART-G

scientific article published on 12 November 2020

A Smartphone App to Restore Optimal Weight (SPAROW) in Women With Recent Gestational Diabetes Mellitus: Randomized Controlled Trial

scientific article

A Smartphone App to Restore Optimal Weight (SPAROW) in Women With Recent Gestational Diabetes Mellitus: Randomized Controlled Trial (Preprint)

scientific article

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A common variant near TGFBR3 is associated with primary open angle glaucoma.

scientific article published on 10 April 2015

A community-based validation study of the short-form 36 version 2 Philippines (Tagalog) in two cities in the Philippines.

scientific article

A deep learning algorithm to detect chronic kidney disease from retinal photographs in community-based populations

scientific article published on 12 May 2020

A family history of type 2 diabetes is associated with glucose intolerance and obesity-related traits with evidence of excess maternal transmission for obesity-related traits in a South East Asian population

scientific article

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

scientific article published on 05 September 2010

A genome-wide association study of n-3 and n-6 plasma fatty acids in a Singaporean Chinese population

scientific article

A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci

scientific journal article

A high carbohydrate, but not fat or protein meal attenuates postprandial ghrelin, PYY and GLP-1 responses in Chinese men.

scientific article published on 31 January 2018

A meta-analysis of genome-wide association studies for adiponectin levels in East Asians identifies a novel locus near WDR11-FGFR2.

scientific article published on 08 October 2013

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A natural polymorphism in peroxisome proliferator-activated receptor-alpha hinge region attenuates transcription due to defective release of nuclear receptor corepressor from chromatin.

scientific article

A novel splice-site mutation in ALS2 establishes the diagnosis of juvenile amyotrophic lateral sclerosis in a family with early onset anarthria and generalized dystonias.

scientific article

A study assessing the association of glycated hemoglobin A1C (HbA1C) associated variants with HbA1C, chronic kidney disease and diabetic retinopathy in populations of Asian ancestry

scientific article

APOE polymorphism and lipid profile in three ethnic groups in the Singapore population

scientific article published in October 2003

ATP binding cassette G5 C1950G polymorphism may affect blood cholesterol concentrations in humans.

scientific article published in September 2002

Adverse Associations between Visceral Adiposity, Brain Structure, and Cognitive Performance in Healthy Elderly

scientific article

Aggregate Effects of Intraocular Pressure and Cup-to-Disc Ratio Genetic Variants on Glaucoma in a Multiethnic Asian Population

scientific article published on 4 March 2015

Allele frequencies of variants in ultra conserved elements identify selective pressure on transcription factor binding

scientific article

Alterations in branched-chain amino acid kinetics in nonobese but insulin-resistant Asian men

article

Altered Motor and Motor Perceptual Cognitive Imagery Task-Related Activation in Diabetic Peripheral Neuropathy: Insights From Functional MRI

scientific article published on 01 October 2019

An Ethics Framework for Big Data in Health and Research

scholarly article by Vicki Xafis et al published September 2019 in Asian Bioethics Review

An Infertile Patient with Abnormal Thyroid-Stimulating Hormone

article

An atlas of genetic scores to predict multi-omic traits

scientific article published on 29 March 2023

An update on cardiovascular disease epidemiology in South East Asia. Rationale and design of the LIFE course study in CARdiovascular disease Epidemiology (LIFECARE)

article

Analysis of non-synonymous-coding variants of Parkinson's disease-related pathogenic and susceptibility genes in East Asian populations

scientific article published on 23 February 2014

Anthropometrics indices of obesity, and all-cause and cardiovascular disease-related mortality, in an Asian cohort with type 2 diabetes mellitus.

scientific article published on 6 January 2015

Association between body mass index and chronic kidney disease in men and women: population-based study of Malay adults in Singapore

scientific article published on 21 December 2007

Association between the PPARA L162V polymorphism and plasma lipid levels: the Framingham Offspring Study

scientific article

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study

scientific article published on 04 September 2019

Association of Diabetic Retinopathy and Diabetic Kidney Disease With All-Cause and Cardiovascular Mortality in a Multiethnic Asian Population

article

Association of Television Viewing Time with Body Composition and Calcified Subclinical Atherosclerosis in Singapore Chinese

scientific article published on July 2015

Association of anthropometric measures with SF-36v2 PCS and MCS in a multi-ethnic Asian population

scientific article published on 21 May 2012

Association of body mass index with Short-Form 36 physical and mental component summary scores in a multiethnic Asian population.

scientific article published on 9 February 2010

Association of diabetes treatment with long-term glycemic patterns in patients with type 2 diabetes mellitus: A prospective cohort study

scientific article published on 10 January 2019

Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore

scientific article published on 10 June 2011

Associations Between Ethnicity, Body Composition, and Bone Mineral Density in a Southeast Asian Population

article

Associations between complications and health-related quality of life in individuals with diabetes.

scientific article published on 25 March 2013

Associations between disease awareness and health-related quality of life in a multi-ethnic Asian population.

scientific article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Associations of diabetes mellitus and ethnicity with mortality in a multiethnic Asian population: data from the 1992 Singapore National Health Survey

scientific article

Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis

scientific article published on 13 March 2014

Associations of physical activity and television viewing time with retinal vascular caliber in a multiethnic Asian population

scientific article

Associations with metabolites in Chinese suggest new metabolic roles in Alzheimer's and Parkinson's diseases

scientific article published on 01 January 2020

Automated segmentation of visceral and subcutaneous (deep and superficial) adipose tissues in normal and overweight men.

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Body fat partitioning does not explain the interethnic variation in insulin sensitivity among Asian ethnicity: the Singapore adults metabolism study

scientific article

Branched-Chain Amino Acid Oxidation Is Elevated in Adults with Morbid Obesity and Decreases Significantly after Sleeve Gastrectomy

scientific article published on 23 October 2020

C-reactive protein and age-related macular degeneration and cataract: the singapore malay eye study

scientific article published on 20 November 2009

C-reactive protein and microalbuminuria in a multi-ethnic Asian population

article

C-reactive protein and retinal microvascular caliber in a multiethnic asian population

scientific article published on 11 December 2009

C-reactive protein and serum creatinine, but not haemoglobin A1c, are independent predictors of coronary heart disease risk in non-diabetic Chinese

scientific article

C-reactive protein, body mass index, and diabetic retinopathy

scientific article published on September 2010

CMPK1 and RBP3 are associated with corneal curvature in Asian populations.

scientific article

CYP2C19 and PON1 polymorphisms regulating clopidogrel bioactivation in Chinese, Malay and Indian subjects

scientific article published in April 2012

Can body fat distribution, adiponectin levels and inflammation explain differences in insulin resistance between ethnic Chinese, Malays and Asian Indians?

scientific article

Can we apply the National Cholesterol Education Program Adult Treatment Panel definition of the metabolic syndrome to Asians?

scientific article published in May 2004

Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe).

scientific article

Cardiac events occurred commonly among apparently healthy Filipinos with the Brugada ECG pattern in the LIFECARE cohort.

scientific article

Cardio-metabolic risk factors and prehypertension in persons without diabetes, hypertension, and cardiovascular disease

scientific article

Cardiovascular risk factors, inflammation, and corneal arcus: the singapore malay eye study

scientific article published on 13 July 2010

Cholesterol-raising diterpenes in types of coffee commonly consumed in Singapore, Indonesia and India and associations with blood lipids: a survey and cross sectional study ⬇️

scientific article (publication date: 15 May 2011)

Chronic kidney disease and intraocular pressure: the Singapore Malay Eye Study

scientific article published on 6 December 2009

Chronic kidney disease, cardiovascular disease and mortality: A prospective cohort study in a multi-ethnic Asian population

article

Clinical significance of apolipoprotein A5

scientific article

Coffee and tea consumption in relation to inflammation and basal glucose metabolism in a multi-ethnic Asian population: a cross-sectional study

scientific article

Coffee, Black Tea, and Green Tea Consumption in Relation to Plasma Metabolites in an Asian Population

scientific article published on 29 October 2020

Cohort Profile: LIFE course study in CARdiovascular disease Epidemiology (LIFECARE)

Cohort Profile: The Singapore Multi-Ethnic Cohort (MEC) study

scientific article published on 13 February 2018

Cohort profile: the Singapore diabetic cohort study

scientific article published on 30 May 2020

Common missense variant in the glucokinase regulatory protein gene is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations

scientific article

Common susceptibility variants are shared between schizophrenia and psoriasis in the Han Chinese population

scientific article published on 18 April 2016

Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies

scientific article published on 12 February 2013

Comprehensive assessment of insulin resistance in non-obese Asian Indian and Chinese men.

scientific article published on 27 March 2018

Consumption of Red Meat, but Not Cooking Oils High in Polyunsaturated Fat, Is Associated with Higher Arachidonic Acid Status in Singapore Chinese Adults

scientific article published on 31 January 2017

Corneal Arcus is a Sign of Cardiovascular Disease, Even in Low-Risk Persons ⬇️

scientific article published on July 13, 2011

Correction: Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation In Vivo.

scientific article

Corrigendum: New loci and coding variants confer risk for age-related macular degeneration in East Asians

scientific article published on 30 March 2015

Cost-effectiveness of a National Telemedicine Diabetic Retinopathy Screening Program in Singapore

scientific article published on 7 October 2016

Cystatin C, chronic kidney disease and retinopathy in adults without diabetes

scientific article published on 29 February 2016

Delivering a Practical Framework for Ethical Decision-Making Involving Big Data in Health and Research

scholarly article by Graeme Laurie & E. Shyong Tai published September 2019 in Asian Bioethics Review

Determinants of Health-Related Quality of Life (HRQoL) in the Multiethnic Singapore Population - A National Cohort Study

scientific article

Determinants of individuals' participation in integrated chronic disease screening in Singapore

scientific article published on 10 June 2016

Diagnosis of diabetes mellitus using HbA1c in Asians: relationship between HbA1c and retinopathy in a multiethnic Asian population

scientific article published on 6 November 2014

Dietary Fat and Protein Intake in Relation to Plasma Sphingolipids as Determined by a Large-Scale Lipidomic Analysis

scientific article published in 2021

Differential association of retinal arteriolar and venular caliber with diabetes and retinopathy

scientific article published on 23 August 2011

Differential effects of the C1431T and Pro12Ala PPARgamma gene variants on plasma lipids and diabetes risk in an Asian population

scientific article published on 16 January 2004

Distribution of ankle—brachial index and the risk factors of peripheral artery disease in a multi-ethnic Asian population ⬇️

scientific article published on March 29, 2011

Does diabetes have an impact on health-state utility? a study of Asians in Singapore

scientific article published in January 2014

Dynamic responses in retinal vessel caliber with flicker light stimulation in eyes with diabetic retinopathy

scientific article published on 15 July 2014

Early retinal arteriolar changes and peripheral neuropathy in diabetes

scientific article published on 28 February 2012

Education influences the association between genetic variants and refractive error: a meta-analysis of five Singapore studies

scientific article published on 06 September 2013

Effect of blood pressure on the retinal vasculature in a multi-ethnic Asian population

scientific article

Elevated serum leptin, adiponectin and leptin to adiponectin ratio is associated with chronic kidney disease in Asian adults

scientific article

Epigenome-wide association of DNA methylation markers in peripheral blood from Indian Asians and Europeans with incident type 2 diabetes: a nested case-control study

scientific article

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

scientific article published on 21 December 2016

Erratum: Corrigendum: Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

scholarly article published in Nature Genetics

Erratum: Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

article

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Establishing the thematic framework for a diabetes-specific health-related quality of life item bank for use in an english-speaking asian population

scientific article

Estimating the number of true discoveries in genome-wide association studies

scientific article published on 11 October 2011

Ethnic Differences in the Role of Adipocytokines Linking Abdominal Adiposity and Insulin Sensitivity Among Asians.

scientific article published on 26 August 2015

Ethnic differences in insulin sensitivity and beta-cell function among Asian men

scientific article published on 20 July 2015

Ethnic differences in the association between blood pressure components and chronic kidney disease in middle aged and older Asian adults

scientific article

Ethnic disparities in prevalence and impact of risk factors of chronic kidney disease

scientific article published on 25 February 2010

Ethnic variation in the impact of metabolic syndrome components and chronic kidney disease

scientific article published on 8 February 2013

Ethnicity modifies the relationships of insulin resistance, inflammation, and adiponectin with obesity in a multiethnic Asian population ⬇️

scientific article

Evaluation of dietary effects on hepatic lipids in high fat and placebo diet fed rats by in vivo MRS and LC-MS techniques.

scientific article

Evaluation of transethnic fine mapping with population-specific and cosmopolitan imputation reference panels in diverse Asian populations

scientific article published on July 2015

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exploring Factors Underlying Ethnic Difference in Age-related Macular Degeneration Prevalence

scientific article published on 08 June 2020

FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals.

scientific article

Factors associated with psychological distress, behavioral impact and health-related quality of life among patients with type 2 diabetes mellitus.

scientific article published on 24 January 2015

Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese

scientific article published on 20 January 2014

Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo

scientific article published in October 2010

Fractal analysis of the retinal vasculature and chronic kidney disease

scientific article published in February 2010

Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia

scientific article

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Genes, diet and serum lipid concentrations: lessons from ethnically diverse populations and their relevance to coronary heart disease in Asia

scientific article published on February 2004

Genetic associations of type 2 diabetes with islet amyloid polypeptide processing and degrading pathways in asian populations

scientific article

Genetic loci for retinal arteriolar microcirculation

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genetic variation in CDH13 is associated with lower plasma adiponectin levels but greater adiponectin sensitivity in East Asian populations

scientific article published on 05 September 2013

Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore

scientific article published on 27 February 2009

Genetic variation in the peroxisome proliferator-activated receptor (PPAR) and peroxisome proliferator-activated receptor gamma co-activator 1 (PGC1) gene families and type 2 diabetes

scientific article published on January 2014

Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

scientific article

Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

scientific article published on 06 January 2013

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

scientific article published on 30 January 2017

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association meta-analysis identifies novel variants associated with fasting plasma glucose in East Asians

scientific article

Genome-wide association studies for blood lipids. A great start but a long way to go

Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference

scientific article published on 20 January 2016

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

scientific article published on 28 January 2016

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

scientific article

Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia

scientific article

Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India

scientific article

Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma

scientific article

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

scientific article

Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci

scientific article published on 03 September 2013

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Glycemic and blood pressure control in an asian malay population with diabetes and diabetic retinopathy

scientific article published on 12 July 2010

Health status of older adults with Type 2 diabetes mellitus after aerobic or resistance training: a randomised trial.

scientific article

Hepatic expression of PPARα, a molecular target of fibrates, is regulated during inflammation in a gender-specific manner

scientific article published on 01 July 2003

Hepatocyte growth factor and retinal arteriolar diameter in Singapore Chinese

scientific article published in February 2010

High-sensitivity troponin T and long-term adverse cardiac events among patients presenting with suspected acute coronary syndrome in Singapore

scientific article published on 18 February 2019

Homeostasis model assessment in a population with mixed ethnicity: the 1992 Singapore National Health Survey

scientific article published in August 2000

Hypertension, Hypertension Control, and Chronic Kidney Disease in a Malay Population in Singapore

scientific article published on 10 May 2010

Hypertension, concurrent cardiovascular risk factors and mortality: the Singapore Cardiovascular Cohort Study

scientific article published on 13 March 2008

Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia

scientific article

Identification of new genetic risk variants for type 2 diabetes

scientific article

Identification of new susceptibility loci for IgA nephropathy in Han Chinese.

scientific article published on June 2015

Identifying candidate causal variants via trans-population fine-mapping.

scientific article

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

Impact of diabetic retinopathy on vision-specific function

scientific article published in February 2010

Impact of sex, metabolic syndrome, and diabetes mellitus on cardiovascular events

scientific article published on 30 May 2007

Increased Burden of Vision Impairment and Eye Diseases in Persons with Chronic Kidney Disease - A Population-Based Study

scientific article published on 19 January 2016

Influence of pre-hypertension on all-cause and cardiovascular mortality: The Singapore Cardiovascular Cohort Study

scientific article published on 26 June 2008

Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis

scientific article

Interaction Between Peroxisome Proliferator Activated Receptor δ and Epithelial Membrane Protein 2 Polymorphisms Influences HDL-C Levels in the Chinese Population.

scientific article published on September 2016

Interethnic analyses of blood pressure loci in populations of East Asian and European descent

scientific article published in Nature Communications

Intragenic linkage disequilibrium structure of the human perilipin gene (PLIN) and haplotype association with increased obesity risk in a multiethnic Asian population

scientific article (publication date: June 2005)

Is chronic kidney disease associated with diabetic retinopathy in Asian adults? 在亚洲成年人中慢性肾病与糖尿病视网膜病变相关吗？

article

Is there a clear threshold for fasting plasma glucose that differentiates between those with and without neuropathy and chronic kidney disease?: the Singapore Prospective Study Program.

scientific article published on 30 April 2009

Isolated low HDL cholesterol: an insulin-resistant state only in the presence of fasting hypertriglyceridemia

scientific article published in May 1999

Joint Effect of Early Microvascular Damage in the Eye &Kidney on Risk of Cardiovascular Events

scientific article published on 08 June 2016

Joint effects of known type 2 diabetes susceptibility loci in genome-wide association study of Singapore Chinese: the Singapore Chinese health study

scientific article

KCNQ1 SNPS and susceptibility to diabetic nephropathy in East Asians with type 2 diabetes

scientific article published on 14 June 2012

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

scientific article

Large-scale lipidomics identifies associations between plasma sphingolipids and T2DM incidence

scientific article published on 04 June 2019

Linking a genome-wide association study signal to a LRRK2 coding variant in Parkinson's disease

scientific article published on 21 December 2015

Longitudinal study of the socio-demographic determinants of changes in body weight and waist circumference in a multi-ethnic Asian population.

scientific article published on 8 September 2009

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

scientific article

Low copy number of the salivary amylase gene predisposes to obesity.

scientific article published on 30 March 2014

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

Lowering the criterion for impaired fasting glucose: impact on disease prevalence and associated risk of diabetes and ischemic heart disease

scientific article

MEDPED comes to Singapore

scientific article published on 01 January 2001

Macro-thyrotropin: a case report and review of literature

scientific article published on 30 March 2012

Meal rich in carbohydrate, but not protein or fat, reveals adverse immunometabolic responses associated with obesity

scientific article published on December 2016

Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease

scientific article published on 18 January 2019

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood

scientific article published on 07 May 2020

Meta-analysis identifies common variants associated with body mass index in east Asians

scientific article published on 19 February 2012

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations

scientific article published on 15 July 2012

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology

scientific article published on 28 January 2015

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

scientific article published on 29 March 2016

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians

scientific article

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

scientific article

Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process

scientific article

Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

scientific article

Meta-analysis of genome-wide association studies in multiethnic Asians identifies two loci for age-related nuclear cataract

article

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci

scientific article

Metabolic gene expression profile in circulating mononuclear cells reflects obesity-associated metabolic inflexibility

scientific article published on 27 October 2016

Metabolic syndrome and mortality in the elderly: a time-dependent association

scientific article published on 30 November 2012

Metabolic syndrome and risk of age-related cataract over time: an analysis of interval-censored data using a random-effects model

scientific article

Metabolic syndrome and risk of age-related macular degeneration

scientific article published in March 2015

Metabolic syndrome components and age-related cataract: the Singapore Malay eye study

scientific article

Methodology of the Singapore Indian Chinese Cohort (SICC) eye study: quantifying ethnic variations in the epidemiology of eye diseases in Asians

scientific article

Minimal difference between aerobic and progressive resistance exercise on metabolic profile and fitness in older adults with diabetes mellitus: a randomised trial

scientific article published on January 2010

Ministry of Health Clinical Practice Guidelines: Diabetes Mellitus.

scientific article

Modification of the NCEP ATP III definitions of the metabolic syndrome for use in Asians identifies individuals at risk of ischemic heart disease

article

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

scientific article published in Nature Communications

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

Multifactorial e- and mHealth interventions for cardiovascular disease primary prevention: Protocol for a systematic review and meta-analysis of randomised controlled trials

scientific article published on 01 January 2019

Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians

scientific article

Navigating conflicts of justice in the use of race and ethnicity in precision medicine

scientific article published on 19 May 2020

New insights into human beta cell biology using human pluripotent stem cells

scientific article published on 19 November 2019

New loci and coding variants confer risk for age-related macular degeneration in East Asians

scientific article

New measure of insulin sensitivity predicts cardiovascular disease better than HOMA estimated insulin resistance

scientific article (publication date: 2013)

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

scientific article

Non-communicable diseases in southeast Asia – Authors' reply

scientific article published in The Lancet

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Nutrigenetics and nutrigenomics: viewpoints on the current status and applications in nutrition research and practice

scientific article

Obesity and the microvasculature: a systematic review and meta-analysis

scientific article

On the usage of HWE for identifying genotyping errors

scientific article published on 27 March 2007

Onset and progression of kidney disease in type 2 diabetes among multi-ethnic Asian population

scientific article published on 24 May 2016

Pathways-driven sparse regression identifies pathways and genes associated with high-density lipoprotein cholesterol in two Asian cohorts

scientific article

Patterns of physical activity in different domains and implications for intervention in a multi-ethnic Asian population: a cross-sectional study

scientific article

Perceived barriers to and ideas for weight control interventions in Malay homemakers: results from focus groups

scientific article published on 12 March 2013

Perilipin Gene Variation Determines Higher Susceptibility to Insulin Resistance in Asian Women When Consuming a High-Saturated Fat, Low-Carbohydrate Diet

article

Peripheral artery disease and glaucoma: the singapore malay eye study.

scientific article published in July 2009

Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children

scientific article

Plasma Metabonomic Profiling of Diabetic Retinopathy

scientific article published on 28 January 2016

Plasma Sphingolipids and Subclinical Atherosclerosis – Novel Associations Uncovered by a Large-scale Lipidomic Analysis (P18-129-19)

Plasma lipoprotein subfraction concentrations are associated with lipid metabolism and age-related macular degeneration

scientific article published on 11 July 2017

Plasma sphingolipids and risk of cardiovascular diseases: a large-scale lipidomic analysis

scientific article published on 20 August 2020

Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population

scientific article

Polymorphisms at the SRBI locus are associated with lipoprotein levels in subjects with heterozygous familial hypercholesterolemia

scientific article

Polymorphisms identified through genome-wide association studies and their associations with type 2 diabetes in Chinese, Malays, and Asian-Indians in Singapore

scientific article published on 5 November 2009

Population differences in associations of serotonin transporter promoter polymorphism (5HTTLPR) di- and triallelic genotypes with blood pressure and hypertension prevalence

scientific article

Precision Medicine and Big Data: The Application of an Ethics Framework for Big Data in Health and Research

scholarly article by G Owen Schaefer et al published September 2019 in Asian Bioethics Review

Predicting preference-based SF-6D index scores from the SF-8 health survey.

scientific article published on 10 October 2012

Prevalence and causes of low vision and blindness in an urban malay population: the Singapore Malay Eye Study

scientific article published on August 2008

Prevalence and risk factors for diabetic retinopathy: the Singapore Malay Eye Study

scientific article published on 26 June 2008

Prevalence and risk factors for peripheral artery disease in an Asian population with diabetes mellitus

scientific article published in April 2009

Prevalence and risk factors for retinopathy in persons without diabetes: the Singapore Indian Eye Study

scientific article published on 3 June 2014

Prevalence of and Risk Factors for Age-Related Macular Degeneration in a Multiethnic Asian Cohort

article

Prevalence of diabetes mellitus, glycemic control, and associated factors in a Malay population in Singapore

scientific article published on 5 August 2009

Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide-field optical coherence tomography in Singapore adults with high myopia

scientific article published on 29 June 2020

Protective Function of Mitogen-Activated Protein Kinase Phosphatase 5 in Aging- and Diet-Induced Hepatic Steatosis and Steatohepatitis

scientific article published on 01 March 2019

Psychometric Properties of the Problem Areas in Diabetes (PAID) Instrument in Singapore

scientific article published on 3 September 2015

Psychometric analysis of an eating behaviour questionnaire for an overweight and obese Chinese population in Singapore.

scientific article published on 2 March 2016

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 01 July 2019

Quantitative retinal vascular calibre changes in diabetes and retinopathy: the Singapore Malay eye study.

scientific article

Racial differences in the prevalence of diabetes but not diabetic retinopathy in a multi-ethnic Asian population

scientific article

Rationale and methodology for a population-based study of eye diseases in Malay people: The Singapore Malay eye study (SiMES).

scientific article published on January 2007

Recalibration of the Global Registry of Acute Coronary Events risk score in a multiethnic Asian population

scientific article

Relation of age-related cataract with obesity and obesity genes in an Asian population

scientific article published on 27 March 2009

Relationship between glycated haemoglobin and microvascular complications: is there a natural cut-off point for the diagnosis of diabetes?

scientific article published on 22 April 2009

Relationship between measured average glucose by continuous glucose monitor and HbA1c measured by three different routine laboratory methods

scientific article published in March 2015

Relationship of Smoking and Cardiovascular Risk Factors with Polypoidal Choroidal Vasculopathy and Age-related Macular Degeneration in Chinese Persons ⬇️

scientific article published on December 13, 2010

Relationship of systemic endothelial function and peripheral arterial stiffness with diabetic retinopathy

Relationships between cholesterol efflux and high-density lipoprotein particles in patients with type 2 diabetes mellitus ⬇️

scientific article published on June 28, 2011

Reliability and validity of the English (Singapore) and Chinese (Singapore) versions of the Short-Form 36 version 2 in a multi-ethnic Urban Asian population in Singapore ⬇️

scientific article published on March 9, 2013

Replication of 13 obesity loci among Singaporean Chinese, Malay and Asian-Indian populations.

scientific article

Reply to: 'Browning capabilities of human primary adipose-derived stromal cells compared to SGBS cells'

scientific article published on 15 June 2020

Retinal arteriolar narrowing increases the likelihood of chronic kidney disease in hypertension.

scientific article published in November 2009

Retinal microvascular abnormalities and risk of renal failure in Asian populations

scientific article

Retinal microvascular caliber and chronic kidney disease in an Asian population

scientific article

Retinal vascular caliber and diabetes in a multiethnic Asian population

scientific article

Retinal vascular caliber, blood pressure, and cardiovascular risk factors in an Asian population: the Singapore Malay Eye Study

scientific article

Retinal vascular fractal and blood pressure in a multiethnic population.

scientific article

Retinal vessel caliber and peripheral neuropathy in diabetic participants

scientific article published on May 2010

Rice and noodle consumption is associated with insulin resistance and hyperglycaemia in an Asian population

scientific article published on 14 November 2013

Risk factors associated with hypertension awareness, treatment, and control in a multi-ethnic Asian population

scientific article published in January 2009

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

article

Screening for diabetes mellitus--a two-step approach in individuals with impaired fasting glucose improves detection of those at risk of complications

scientific article published in November 2000

Screening for diabetes with HbA1c: Test performance of HbA1c compared to fasting plasma glucose among Chinese, Malay and Indian community residents in Singapore

scientific article published in Scientific Reports

Sensitivity of three widely used questionnaires for measuring psychological distress among patients with type 2 diabetes mellitus.

scientific article

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Serum C-reactive protein level and prediabetes in two Asian populations

scientific article published on 26 January 2011

Serum C-reactive protein level and prehypertension in two Asian populations

scientific article published on 15 March 2012

Serum Cystatin C, Markers of Chronic Kidney Disease, and Retinopathy in Persons with Diabetes

scientific article

SgD-CNV, a database for common and rare copy number variants in three Asian populations

scientific article published on 30 September 2011

Sharing precision medicine data with private industry: Outcomes of a citizens’ jury in Singapore

scientific article published in 2022

Short-term strength and balance training does not improve quality of life but improves functional status in individuals with diabetic peripheral neuropathy: a randomised controlled trial ⬇️

scientific article published on 29 August 2019

Should Central Obesity Be an Optional or Essential Component of the Metabolic Syndrome?: Ischemic heart disease risk in the Singapore Cardiovascular Cohort Study

scientific article published on 01 February 2007

Singapore Malay Eye Study: rationale and methodology of 6‐year follow‐up study (SiMES‐2) ⬇️

scientific article published on March 27, 2012

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

scientific article

Smaller size of high metabolic rate organs explains lower resting energy expenditure in Asian-Indian Than Chinese men.

scientific article published on 16 November 2015

Smart Phone APP to Restore Optimal Weight (SPAROW): protocol for a randomised controlled trial for women with recent gestational diabetes

scientific article published on 15 October 2019

Socioeconomic status and microalbuminuria in an Asian population

scientific article published on 6 August 2008

Structural changes in the retinal microvasculature and renal function

scientific article

Television screen time, but not computer use and reading time, is associated with cardio-metabolic biomarkers in a multiethnic Asian population: a cross-sectional study

scientific article published on 30 May 2013

The APOA5 locus is a strong determinant of plasma triglyceride concentrations across ethnic groups in Singapore

scientific article (publication date: December 2003)

The ARIC predictive model reliably predicted risk of type II diabetes in Asian populations

scientific article

The EQ-5D-5L is More Discriminative Than the EQ-5D-3L in Patients with Diabetes in Singapore

scientific article published on 19 January 2016

The Great Masquerador: A Young Female with Multiple Endocrine Neoplasia Type 2A and Bilateral Pheochromocytomas

scientific article published on 17 May 2019

The Impact of Central Obesity as a Prerequisite for the Diagnosis of Metabolic Syndrome*

scientific article published on 01 January 2007

The L162V polymorphism at the peroxisome proliferator activated receptor alpha locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: the Veterans Affairs HDL Intervention Trial (VA-HIT).

scientific article published on 10 October 2005

The Patient Activation through Community Empowerment/Engagement for Diabetes Management (PACE-D) protocol: a non-randomised controlled trial of personalised care and support planning for persons living with diabetes

scientific article published on 19 June 2020

The Prevalence of Gestational Diabetes Mellitus Among Asian Females is Lower Using the New 2013 World Health Organization Diagnostic Criteria

scientific article published in October 2014

The Short Form 36 English and Chinese versions were equivalent in a multiethnic Asian population.

scientific article published on 27 March 2013

The Singapore impaired glucose tolerance follow-up study: does the ticking clock go backward as well as forward?

scientific article published on November 2003

The TaqIB and -629C>A polymorphisms at the cholesteryl ester transfer protein locus: associations with lipid levels in a multiethnic population. The 1998 Singapore National Health Survey

scientific article

The V227A polymorphism at the PPARA locus is associated with serum lipid concentrations and modulates the association between dietary polyunsaturated fatty acid intake and serum high density lipoprotein concentrations in Chinese women

scientific article

The association between socioeconomic status and overweight/obesity in a Malay population in Singapore

scientific article

The babel of the ABCs: novel transporters involved in the regulation of sterol absorption and excretion

scientific article

The case for strategic international alliances to harness nutritional genomics for public and personal health

scientific article published in November 2005

The contribution of recently identified adult BMI risk loci to paediatric obesity in a Singaporean Chinese childhood dataset

scientific article published on 25 October 2016

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The lipoprotein lipase S447X polymorphism and plasma lipids: interactions with APOE polymorphisms, smoking, and alcohol consumption

scientific article published in April 2004

The metabolic syndrome and mortality: the Singapore Cardiovascular Cohort Study

scientific article published on 15 January 2008

The metabolic syndrome in Chinese, Malays and Asian Indians. Factor analysis of data from the 1998 Singapore National Health Survey

scientific article

The prognostic role of body mass index on mortality amongst the middle-aged and elderly: a competing risk analysis

scientific article published on 12 December 2013

The rise of chronic non-communicable diseases in southeast Asia: time for action ⬇️

scientific article published on January 25, 2011

The role of perilipin in human obesity and insulin resistance

scientific article

Toll-like receptor 3 polymorphism rs3775291 is not associated with choroidal neovascularization or polypoidal choroidal vasculopathy in Chinese subjects

scientific article published on 16 November 2010

Towards longitudinal analysis of a population's electronic health records using factor graphs

article

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms

scientific article published on 23 February 2016

Two-Hour Postprandial Lipoprotein Particle Concentration Differs Between Lean and Obese Individuals

scientific article published on 16 July 2019

Understanding diet-gene interactions: lessons from studying nutrigenomics and cardiovascular disease

scientific article published on 5 May 2007

Using marginal standardisation to estimate relative risk without dichotomising continuous outcomes

scientific article published on 29 July 2019

Utilizing distributional analytics and electronic records to assess timeliness of inpatient blood glucose monitoring in non-critical care wards

scientific article

Validity of the International Physical Activity Questionnaire and the Singapore Prospective Study Program physical activity questionnaire in a multiethnic urban Asian population

scientific article

Validity of the Thai EQ-5D in an occupational population in Thailand.

scientific article published on 25 August 2012

Visceral adipose tissue, but not waist circumference is a better measure of metabolic risk in Singaporean Chinese and Indian men ⬇️

scientific article published on August 6, 2012

Why study gene-environment interactions?

scientific article published on April 2008

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

scholarly article

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