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List of works by Gerry McLachlan

A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis

scientific article

Aerosol delivery of DNA/liposomes to the lung for cystic fibrosis gene therapy.

scientific article published on 27 May 2014

Age-related differences in the respiratory microbiota of chickens.

scientific article

An epidemiological survey on the prevalence of equine peripheral dental caries in the United Kingdom and possible risk factors for its development

scientific article published on 16 July 2016

An immunocytochemical assay to detect human CFTR expression following gene transfer

scientific article

Analysis of airway epithelial regeneration and repair following endobronchial brush biopsy in sheep

scientific article published on 06 September 2011

BrdU pulse labelling in vivo to characterise cell proliferation during regeneration and repair following injury to the airway wall in sheep

scientific article published on 28 February 2013

Chemokine and cytokine expression in murine intestinal epithelium following Nippostrongylus brasiliensis infection.

scientific article published on February 2002

Comparing microbiotas in the upper aerodigestive and lower respiratory tracts of lambs

scientific article published on 27 October 2017

Electroporation enhances reporter gene expression following delivery of naked plasmid DNA to the lung.

scientific article published in May 2007

Enhanced Lung Gene Expression After Aerosol Delivery of Concentrated pDNA/PEI Complexes

article

Evaluation of nebulised hay dust suspensions (HDS) for the diagnosis and investigation of heaves. 1: Preparation and composition of HDS.

scientific article published in July 2002

Factors affecting the efficiency of aerosolized salbutamol delivery via a metered dose inhaler and equine spacer device

scientific article published on 4 September 2016

Gene expression changes associated with the airway wall response to injury.

scientific article

Grazing livestock are exposed to terrestrial cyanobacteria.

scientific article published on 25 February 2015

Growth inhibition of the MOLT-4 human T-leukemia cell line. A comparison of cyclosporine and FK 506

scientific article published on December 1, 1991

Human-specific cystic fibrosis transmembrane conductance regulator antibodies detect in vivo gene transfer to ovine airways

scientific article published on 23 February 2006

Laboratory and clinical studies in support of cystic fibrosis gene therapy using pCMV-CFTR-DOTAP.

scientific article

Lung Microbiota Changes Associated with Chronic Pseudomonas aeruginosa Lung Infection and the Impact of Intravenous Colistimethate Sodium

scientific article

Lung disease in the cystic fibrosis mouse exposed to bacterial pathogens

scientific article published on 01 April 1995

Microbiota in Exhaled Breath Condensate and the Lung

scientific article published on 7 April 2017

Nebulisation of synthetic lamellar lipids mitigates radiation-induced lung injury in a large animal model

scientific article published in Scientific Reports

Optimizing aerosol gene delivery and expression in the ovine lung

scientific article published on February 2007

Ovine induced pluripotent stem cells are resistant to reprogramming after nuclear transfer

scientific article published on 16 December 2014

Plasmid DNA molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolisation.

scientific article

Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung.

scientific article published on 21 April 2011

Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis.

scientific article

Regulation of pulmonary and systemic bacterial lipopolysaccharide responses in transgenic mice expressing human elafin

scientific article

Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial.

scientific article

Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer.

scientific article published on 15 January 2011

The potential of cyclosporin A as an anti-tumour agent.

scientific article published on January 1990

The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep.

scientific article published on 3 October 2013

Toxicology study assessing efficacy and safety of repeated administration of lipid/DNA complexes to mouse lung

scientific article published on 7 November 2013

Transfection efficiency and toxicity following delivery of naked plasmid DNA and cationic lipid–DNA complexes to ovine lung segments ⬇️

scientific article published on October 1, 2003

Transgenic sheep designed for transplantation studies.

scientific article published in January 2009

Validation of recombinant Sendai virus in a non-natural host model.

scientific article published on 21 October 2010

Variability of the Sheep Lung Microbiota.

scientific article published on 18 March 2016

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