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List of works by Fermin I Milagro

A beta3-adrenergic agonist increases muscle GLUT1/GLUT4 ratio, and regulates liver glucose utilization in diabetic rats

scientific article published on 01 March 1999

A combination of borage seed oil and quercetin reduces fat accumulation and improves insulin sensitivity in obese rats

scientific article published on 11 May 2020

A dual epigenomic approach for the search of obesity biomarkers: DNA methylation in relation to diet-induced weight loss.

scientific article

A genetic risk tool for obesity predisposition assessment and personalized nutrition implementation based on macronutrient intake.

scientific article

Adherence to Mediterranean diet is associated with methylation changes in inflammation-related genes in peripheral blood cells.

scientific article

Adiposity dependent apelin gene expression: relationships with oxidative and inflammation markers

article

Adiposoft: automated software for the analysis of white adipose tissue cellularity in histological sections.

scientific article

An integrated transcriptomic and epigenomic analysis identifies CD44 gene as a potential biomarker for weight loss within an energy-restricted program

article

Antidiabetic effects of natural plant extracts via inhibition of carbohydrate hydrolysis enzymes with emphasis on pancreatic alpha amylase ⬇️

scientific article published on February 24, 2012

Ascorbic acid oral treatment modifies lipolytic response and behavioural activity but not glucocorticoid metabolism in cafeteria diet-fed rats.

scientific article published on 25 November 2008

Association between Sleep Disturbances and Liver Status in Obese Subjects with Nonalcoholic Fatty Liver Disease: A Comparison with Healthy Controls

scientific article published on 02 February 2019

Association of Methylation Signatures at Hepatocellular Carcinoma Pathway Genes with Adiposity and Insulin Resistance Phenotypes

scientific article published on 20 November 2018

Association of low dietary folate intake with lower CAMKK2 gene methylation, adiposity, and insulin resistance in obese subjects

scientific article

Association of the Gly482Ser PPARGC1A gene variant with different cholesterol outcomes in response to two energy-restricted diets in subjects with excessive weight

scientific article published on 4 January 2018

Association of the SH2B1 rs7359397 Gene Polymorphism with Steatosis Severity in Subjects with Obesity and Non-Alcoholic Fatty Liver Disease

scientific article published on 29 April 2020

Association of weight regain with specific methylation levels in the NPY and POMC promoters in leukocytes of obese men: a translational study

scientific article published on 5 July 2013

Associations between olfactory pathway gene methylation marks, obesity features and dietary intakes

article

Biochemical profile, eating habits, and telomere length among Brazilian children and adolescents

scientific article published on 09 November 2019

CLOCK, PER2 and BMAL1 DNA methylation: association with obesity and metabolic syndrome characteristics and monounsaturated fat intake.

scientific article

Changes in Anxiety and Depression Traits Induced by Energy Restriction: Predictive Value of the Baseline Status

scientific article published on 28 May 2019

Chronic benzylamine administration in the drinking water improves glucose tolerance, reduces body weight gain and circulating cholesterol in high-fat diet-fed mice

scientific article published on 4 January 2010

Circadian expression of adiponectin and its receptors in human adipose tissue

scientific article

Circadian gene methylation profiles are associated with obesity, metabolic disturbances and carbohydrate intake.

scientific article published on 26 March 2018

Circulating adiposity-related microRNAs as predictors of the response to a low-fat diet in subjects with obesity

scientific article published on 22 January 2020

Common variants in genes related to lipid and energy metabolism are associated with weight loss after an intervention in overweight/obese adolescents

scientific article published in July 2014

Comparative effects of energy restriction and resveratrol intake on glycemic control improvement.

scientific article published on 20 February 2017

Comprehensive Analysis Reveals Novel Interactions between Circulating MicroRNAs and Gut Microbiota Composition in Human Obesity

scientific article published on 14 December 2020

Crosstalk between circulating microRNAs and chronotypical features in subjects with metabolic syndrome

scientific article published on 07 July 2020

Crosstalk between microRNAs, the putative target genes and the lncRNA network in metabolic diseases

scientific article published on 21 August 2019

DNA Methylation and Hydroxymethylation Levels in Relation to Two Weight Loss Strategies: Energy-Restricted Diet or Bariatric Surgery.

scientific article published on 22 July 2015

DNA methylation in genes of longevity-regulating pathways: association with obesity and metabolic complications

article

DNA methylation in promoter regions of genes involved in the reproductive and metabolic function of children born to women with PCOS

scientific article published on 14 April 2020

DNA methylation map in circulating leukocytes mirrors subcutaneous adipose tissue methylation pattern: a genome-wide analysis from non-obese and obese patients.

scientific article published on 17 February 2017

DNA methylation markers in obesity, metabolic syndrome, and weight loss

scientific article published on 27 March 2019

DNA methylation of miRNA coding sequences putatively associated with childhood obesity

scientific article published on 19 January 2016

DNA methylation pattern in overweight women under an energy-restricted diet supplemented with fish oil.

scientific article published on 22 January 2014

DNA methylation patterns at sweet taste transducing genes are associated with BMI and carbohydrate intake in an adult population.

scientific article published on 6 September 2017

DNA methylation signatures at endoplasmic reticulum stress genes are associated with adiposity and insulin resistance

scientific article published on 28 November 2017

Diet, Gut Microbiota, and Obesity: Links with Host Genetics and Epigenetics and Potential Applications

scientific article published on 01 January 2019

Dietary factors, epigenetic modifications and obesity outcomes: progresses and perspectives.

scientific article published on 04 July 2012

Dietary supplementation with methyl donor groups could prevent nonalcoholic fatty liver

scientific article published on 29 April 2011

Dietary supplementation with methyl donors reduces fatty liver and modifies the fatty acid synthase DNA methylation profile in rats fed an obesogenic diet.

scientific article published on 31 May 2012

Differential DNA Methylation in Relation to Age and Health Risks of Obesity

scientific article

Differential Expression of Oxidative Stress and Inflammation Related Genes in Peripheral Blood Mononuclear Cells in Response to a Low-Calorie Diet: A Nutrigenomics Study

article

Differential expression of aquaporin 7 in adipose tissue of lean and obese high fat consumers.

scientific article

Differential lipid metabolism outcomes associated with ADRB2 gene polymorphisms in response to two dietary interventions in overweight/obese subjects.

scientific article published on 5 December 2017

Differentially methylated regions (DMRs) in PON3 gene between responders and non-responders to a weight loss dietary intervention: a new tool for precision management of obesity

scientific article published on 25 January 2021

Do the Effects of Resveratrol on Thermogenic and Oxidative Capacities in IBAT and Skeletal Muscle Depend on Feeding Conditions?

scientific article published on 06 October 2018

Dopamine gene methylation patterns are associated with obesity markers and carbohydrate intake

article

Effect of DHEA-sulfate on adiponectin gene expression in adipose tissue from different fat depots in morbidly obese humans.

scientific article published in October 2006

Effect of TNF-Alpha on Caveolin-1 Expression and Insulin Signaling During Adipocyte Differentiation and in Mature Adipocytes

scientific article published on 6 July 2015

Effect of hypoxia on caveolae-related protein expression and insulin signaling in adipocytes.

scientific article published on 30 January 2018

Effect of the interaction between diet composition and the PPM1K genetic variant on insulin resistance and β cell function markers during weight loss: results from the Nutrient Gene Interactions in Human Obesity: implications for dietary guidelines

article

Effects of exosomes from LPS-activated macrophages on adipocyte gene expression, differentiation, and insulin-dependent glucose uptake

scientific article published on 20 March 2018

Effects of perinatal diet and prenatal stress on the behavioural profile of aged male and female rats

scientific article published in January 2017

Effects of the oral administration of a beta3-adrenergic agonist on lipid metabolism in alloxan-diabetic rats

scientific article published on 01 July 2000

Effects of trecadrine, a beta 3-adrenergic agonist, on intestinal absorption of D-galactose and disaccharidase activities in three physiopathological models

scientific article published on 01 September 1997

Endoplasmic reticulum stress epigenetics is related to adiposity, dyslipidemia, and insulin resistance

journal article; published in Adipocyte in 2018

Epigenetic Changes in the Methylation Patterns of KCNQ1 and WT1 after a Weight Loss Intervention Program in Obese Stroke Patients.

scientific article published on 31 July 2015

Epigenetic Modifications as Outcomes of Exercise Interventions Related to Specific Metabolic Alterations: A Systematic Review

scientific article published on 23 September 2019

Epigenetic patterns of two gene promoters (TNF-α and PON) in stroke considering obesity condition and dietary intake.

scientific article published on 7 February 2014

Epigenetic signatures underlying inflammation: an interplay of nutrition, physical activity, metabolic diseases, and environmental factors for personalized nutrition

scientific article published on 24 November 2020

Epigenetics and obesity.

scientific article published on January 2010

Epigenetics in adipose tissue, obesity, weight loss, and diabetes

scientific article published on January 2014

Epigenetics of obesity and weight loss.

scientific article published in January 2013

Epigenome-wide association study in peripheral white blood cells involving insulin resistance

scientific article published on 21 February 2019

Expression of Caveolin 1 is enhanced by DNA demethylation during adipocyte differentiation. status of insulin signaling

scientific article

Expression of cortisol metabolism-related genes shows circadian rhythmic patterns in human adipose tissue.

scientific article published on 10 February 2009

Expression of inflammation-related miRNAs in white blood cells from subjects with metabolic syndrome after 8 wk of following a Mediterranean diet-based weight loss program.

scientific article published on 17 July 2015

Extrusion decreases the negative effects of kidney bean on enzyme and transport activities of the rat small intestine

scientific article published on 26 November 2010

Fat intake leads to differential response of rat adipocytes to glucose, insulin and ascorbic acid

scientific article published on 27 March 2012

Fat-to-glucose interconversion by hydrodynamic transfer of two glyoxylate cycle enzyme genes

scientific article published on 10 December 2008

Fatty acids, epigenetic mechanisms and chronic diseases: a systematic review

scientific article published on 15 October 2019

Folic Acid Improves the Inflammatory Response in LPS-Activated THP-1 Macrophages

scientific article published on 04 July 2018

Freeze-dried strawberry and blueberry attenuates diet-induced obesity and insulin resistance in rats by inhibiting adipogenesis and lipogenesis.

scientific article published on 12 October 2017

Future Perspectives of Personalized Weight Loss Interventions Based on Nutrigenetic, Epigenetic, and Metagenomic Data

scientific article

Future challenges and present ethical considerations in the use of personalized nutrition based on genetic advice.

scientific article

Gene expression changes in rat white adipose tissue after a high-fat diet determined by differential display

scientific journal article

Gene methylation parallelisms between peripheral blood cells and oral mucosa samples in relation to overweight

scientific article

Gene-Gene Interplay and Gene-Diet Interactions Involving the MTNR1B rs10830963 Variant with Body Weight Loss

scientific article

Genetic and nongenetic factors explaining metabolically healthy and unhealthy phenotypes in participants with excessive adiposity: relevance for personalized nutrition

scientific article published on 18 September 2019

Guide and Position of the International Society of Nutrigenetics/Nutrigenomics on Personalised Nutrition: Part 1 - Fields of Precision Nutrition

scientific article published on 12 May 2016

Guide for Current Nutrigenetic, Nutrigenomic, and Nutriepigenetic Approaches for Precision Nutrition Involving the Prevention and Management of Chronic Diseases Associated with Obesity

scientific article published on 8 July 2017

Healthy properties of proanthocyanidins.

scientific article published on May 2010

Helichrysum and Grapefruit Extracts Boost Weight Loss in Overweight Rats Reducing Inflammation.

scientific article published on 19 January 2015

Helichrysum and grapefruit extracts inhibit carbohydrate digestion and absorption, improving postprandial glucose levels and hyperinsulinemia in rats.

scientific article published on 27 November 2013

High fat diet-induced obesity modifies the methylation pattern of leptin promoter in rats

scientific article published on 01 March 2009

High-fat diet feeding alters metabolic response to fasting/non fasting conditions. Effect on caveolin expression and insulin signalling.

scientific article

High-fat feeding period affects gene expression in rat white adipose tissue

scientific journal article

High-throughput sequencing of microRNAs in peripheral blood mononuclear cells: identification of potential weight loss biomarkers.

scientific article

Higher Fruit Intake Is Related to TNF-α Hypomethylation and Better Glucose Tolerance in Healthy Subjects.

scientific article published on 29 July 2016

Hypolipidemic properties of a diphenyl-methylen-ethylamine derivative with affinity for β3-adrenoceptors in a model of hypercholesterolemia

scientific article published on 01 October 1999

Immunoneutralization and anti-idiotype production: two-sided applications of leptin

article

Impact of Consuming Extra-Virgin Olive Oil or Nuts within a Mediterranean Diet on DNA Methylation in Peripheral White Blood Cells within the PREDIMED-Navarra Randomized Controlled Trial: A Role for Dietary Lipids

scientific article published on 23 December 2017

Impact of polyphenols and polyphenol-rich dietary sources on gut microbiota composition

scientific article

Implication of Trimethylamine N-Oxide (TMAO) in Disease: Potential Biomarker or New Therapeutic Target

scientific article published on 01 October 2018

Implication of miR-612 and miR-1976 in the regulation of TP53 and CD40 and their relationship in the response to specific weight-loss diets

scientific article published in PLoS ONE

Individuality and epigenetics in obesity.

scientific article

Inflammation and gut-brain axis link obesity to cognitive dysfunction: plausible pharmacological interventions.

scientific article published on 3 November 2017

Influence of dietary macronutrient composition on adiposity and cellularity of different fat depots in Wistar rats.

scientific article published in December 2009

Influence of fat intake and BMI on the association of rs1799983 NOS3 polymorphism with blood pressure levels in an Iberian population

scientific article published on 19 March 2016

Inhibition of serum cholesterol oxidation by dietary vitamin C and selenium intake in high fat fed rats.

scientific article published on 12 March 2008

Insulin Sensitivity Is Associated with Lipoprotein Lipase (LPL) and Catenin Delta 2 (CTNND2) DNA Methylation in Peripheral White Blood Cells in Non-Diabetic Young Women

scientific article published on 15 June 2019

Interaction Among Sex, Aging, and Epigenetic Processes Concerning Visceral Fat, Insulin Resistance, and Dyslipidaemia

scientific article published on 17 July 2019

Interaction between an ADCY3 Genetic Variant and Two Weight-Lowering Diets Affecting Body Fatness and Body Composition Outcomes Depending on Macronutrient Distribution: A Randomized Trial.

scientific article published on 19 June 2018

Interleukin-6 is a better metabolic biomarker than interleukin-18 in young healthy adults

scientific article published on 27 February 2015

Interplay of an Obesity-Based Genetic Risk Score with Dietary and Endocrine Factors on Insulin Resistance

scientific article published on 21 December 2019

Involvement of autophagy in the beneficial effects of resveratrol in hepatic steatosis treatment. A comparison with energy restriction

scientific article published on 01 August 2018

Involvement of miR-539-5p in the inhibition of de novo lipogenesis induced by resveratrol in white adipose tissue.

scientific article published on 8 March 2016

LINE-1 and inflammatory gene methylation levels are early biomarkers of metabolic changes: association with adiposity

scientific article published on 21 April 2016

LINE-1 methylation is positively associated with healthier lifestyle but inversely related to body fat mass in healthy young individuals.

scientific article published on 19 January 2016

LINE-1 methylation levels, a biomarker of weight loss in obese subjects, are influenced by dietary antioxidant capacity.

scientific article published on 21 July 2015

Leptin and TNF-alpha promoter methylation levels measured by MSP could predict the response to a low-calorie diet.

scientific article published on 5 April 2011

Liver Proteome Changes Induced by a Short-Term High-Fat Sucrose Diet in Wistar Rats

scientific article published on 01 January 2011

Low doses of cocoa extract supplementation ameliorate diet-induced obesity and insulin resistance in rats

scientific article published on 18 July 2019

Maternal methyl donors supplementation during lactation prevents the hyperhomocysteinemia induced by a high-fat-sucrose intake by dams

scientific article published on 16 December 2013

Mechanisms involved in BACE upregulation associated to stress.

scientific article published on September 2012

Metabolic faecal fingerprinting of trans-resveratrol and quercetin following a high-fat sucrose dietary model using liquid chromatography coupled to high-resolution mass spectrometry

scientific article

Methyl donor supplementation in rats reverses the deleterious effect of maternal separation on depression-like behaviour

scientific article published on 25 November 2015

Methylation changes and pathways affected in preterm birth: a role for SLC6A3 in neurodevelopment

scientific article published on 27 November 2017

Methylation on the Circadian Gene BMAL1 Is Associated with the Effects of a Weight Loss Intervention on Serum Lipid Levels.

scientific article published on 11 February 2016

Methylome-Wide Association Study in Peripheral White Blood Cells Focusing on Central Obesity and Inflammation

scientific article published on 11 June 2019

MicroRNAs and other non-coding RNAs in adipose tissue and obesity: emerging roles as biomarkers and therapeutic targets

scientific article published on 03 January 2019

Modeling of an integrative prototype based on genetic, phenotypic, and environmental information for personalized prescription of energy-restricted diets in overweight/obese subjects

scientific article published on 01 February 2020

Models Integrating Genetic and Lifestyle Interactions on Two Adiposity Phenotypes for Personalized Prescription of Energy-Restricted Diets With Different Macronutrient Distribution

scientific article published on 30 July 2019

Modulation of hyperglycemia and TNFα-mediated inflammation by helichrysum and grapefruit extracts in diabetic db/db mice.

scientific article published in September 2014

Natural inhibitors of pancreatic lipase as new players in obesity treatment.

scientific article

Noncoding RNAs, cytokines, and inflammation-related diseases

scientific article published on 11 June 2015

Obesity and ischemic stroke modulate the methylation levels of KCNQ1 in white blood cells.

scientific article published on 4 November 2014

Obesity induced by a pair-fed high fat sucrose diet: methylation and expression pattern of genes related to energy homeostasis.

scientific article

Oral Phenelzine Treatment Mitigates Metabolic Disturbances in Mice Fed a High-Fat Diet

scientific article published on 03 July 2019

PPARGC1A Gene Promoter Methylation as a Biomarker of Insulin Secretion and Sensitivity in Response to Glucose Challenges

scientific article published on 11 September 2020

PTPRS and PER3 methylation levels are associated with childhood obesity: results from a genome-wide methylation analysis

scientific article published on 14 June 2017

Pediococcus acidilactici CECT9879 (pA1c) Counteracts the Effect of a High-Glucose Exposure in C. elegans by Affecting the Insulin Signaling Pathway (IIS)

scientific article published in 2022

Perinatal maternal feeding with an energy dense diet and/or micronutrient mixture drives offspring fat distribution depending on the sex and growth stage.

scientific article published on 18 December 2014

Peripheral blood mononuclear cell gene expression profile in obese boys who followed a moderate energy-restricted diet: differences between high and low responders at baseline and after the intervention

scientific article published on 4 December 2014

Phenolic Compounds Inhibit 3T3-L1 Adipogenesis Depending on the Stage of Differentiation and Their Binding Affinity to PPARγ

scientific article published on 16 March 2019

Phenolic Compounds Reduce the Fat Content in Caenorhabditis elegans by Affecting Lipogenesis, Lipolysis, and Different Stress Responses

scientific article published on 30 October 2020

Phenotype and genotype predictors of BMI variability among European adults.

scientific article published on 24 May 2018

Plasma lactate and leukocyte mitochondrial DNA copy number as biomarkers of insulin sensitivity in non-diabetic women

scientific article published on 13 March 2019

Precision Obesity Treatments Including Pharmacogenetic and Nutrigenetic Approaches.

scientific article published on 25 May 2016

Prediction of Blood Lipid Phenotypes Using Obesity-Related Genetic Polymorphisms and Lifestyle Data in Subjects with Excessive Body Weight

scientific article published on 19 November 2018

Prevention of diet-induced obesity by apple polyphenols in Wistar rats through regulation of adipocyte gene expression and DNA methylation patterns.

scientific article published on 25 March 2013

Proposed guidelines to evaluate scientific validity and evidence for genotype-based dietary advice

scientific article published on 15 December 2017

Pterostilbene-induced changes in gut microbiota composition in relation to obesity.

scientific article published on 5 July 2016

Regulation by chronic-mild stress of glucocorticoids, monocyte chemoattractant protein-1 and adiposity in rats fed on a high-fat diet

scientific article published on 22 January 2011

Regulatory roles of miR-155 and let-7b on the expression of inflammation-related genes in THP-1 cells: effects of fatty acids

scientific article published on 22 May 2018

Reshaping faecal gut microbiota composition by the intake of trans-resveratrol and quercetin in high-fat sucrose diet-fed rats.

scientific article published on 26 February 2015

Resveratrol attenuates steatosis in obese Zucker rats by decreasing fatty acid availability and reducing oxidative stress.

scientific article published on 28 June 2011

SH2B1 CpG-SNP is associated with body weight reduction in obese subjects following a dietary restriction program.

scientific article published on 2 December 2014

Screening of polyphenolic plant extracts for anti-obesity properties in Wistar rats

article

Sex-Specific Associations between Gut Prevotellaceae and Host Genetics on Adiposity

scientific article published on 22 June 2020

Shifting to a control diet after a high-fat, high-sucrose diet intake induces epigenetic changes in retroperitoneal adipocytes of Wistar rats.

scientific article

Shifts in microbiota species and fermentation products in a dietary model enriched in fat and sucrose.

scientific article

Single-nucleotide polymorphisms and DNA methylation markers associated with central obesity and regulation of body weight.

scientific article

Some cyclin-dependent kinase inhibitors-related genes are regulated by vitamin C in a model of diet-induced obesity.

scientific article published in August 2009

Supplementation with methyl donors during lactation to high-fat-sucrose-fed dams protects offspring against liver fat accumulation when consuming an obesogenic diet

scientific article published in August 2014

TNF-alpha promoter methylation in peripheral white blood cells: relationship with circulating TNFα, truncal fat and n-6 PUFA intake in young women.

scientific article published on 21 June 2013

Techniques of DNA methylation analysis with nutritional applications.

scientific article published on 08 May 2013

The effect of trans-10,cis-12 conjugated linoleic acid on lipogenesis is tissue dependent in hamsters

scientific article published on October 2007

The regulation of inflammation-related genes after palmitic acid and DHA treatments is not mediated by DNA methylation

scientific article published on 19 August 2019

The rs7204609 polymorphism in the fat mass and obesity-associated gene is positively associated with central obesity and microalbuminuria in patients with type 2 diabetes from Southern Brazil.

scientific article published on 13 July 2011

Therapeutic perspectives of epigenetically active nutrients.

scientific article published on 15 December 2014

Time-dependent regulation of muscle caveolin activation and insulin signalling in response to high-fat diet.

scientific article

Transcriptomic and epigenetic changes in early liver steatosis associated to obesity: effect of dietary methyl donor supplementation.

scientific article published on 17 September 2013

Transcriptomic and epigenetic changes in the hypothalamus are involved in an increased susceptibility to a high-fat-sucrose diet in prenatally stressed female rats.

scientific article published on 19 September 2012

Vitamin C modulates the interaction between adipocytes and macrophages.

scientific article published on 28 July 2011

Vitamin C supplementation influences body fat mass and steroidogenesis-related genes when fed a high-fat diet.

scientific article

miR-1185-1 and miR-548q Are Biomarkers of Response to Weight Loss and Regulate the Expression of GSK3B

scientific article published on 30 November 2019

miRNAs and Novel Food Compounds Related to the Browning Process

scientific article published on 28 November 2019

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