List of works - Marisa Freitas

2,3-diarylxanthones as strong scavengers of reactive oxygen and nitrogen species: a structure-activity relationship study.

scientific article published on 25 July 2010

A comprehensive review on xanthone derivatives as α-glucosidase inhibitors

A study towards drug discovery for the management of type 2 diabetes mellitus through inhibition of the carbohydrate-hydrolyzing enzymes α-amylase and α-glucosidase by chalcone derivatives

scientific article published on 15 August 2019

Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils

scientific article published on 18 March 2013

Analysis of the use of microcystin-contaminated water in the growth and nutritional quality of the root-vegetable, Daucus carota

scientific article

Anti-inflammatory Effects of Persimmon (Diospyros kaki L.) in Experimental Rodent Rheumatoid Arthritis

scientific article published on 30 July 2019

Anti-inflammatory effect of rosmarinic acid and an extract of Rosmarinus officinalis in rat models of local and systemic inflammation

scientific article published on 6 November 2014

Antioxidant activity of unexplored indole derivatives: Synthesis and screening ⬇️

scientific article published on August 6, 2010

Antioxidant and pro-oxidant activities of carotenoids and their oxidation products

scientific article published on 02 August 2018

Application of real-time PCR in the assessment of the toxic cyanobacterium Cylindrospermopsis raciborskii abundance and toxicological potential.

scientific article

Bioaccessibility and changes on cylindrospermopsin concentration in edible mussels with storage and processing time

Bioactive compounds and scavenging capacity of extracts from different parts of Vismia cauliflora against reactive oxygen and nitrogen species.

scientific article

Biodistribution of polyacrylic acid-coated iron oxide nanoparticles is associated with proinflammatory activation and liver toxicity

scientific article

Biological activities of 2-styrylchromones.

scientific article published on January 2010

Calcium Pathways in Human Neutrophils-The Extended Effects of Thapsigargin and ML-9

scientific article published on 09 November 2018

Carotenoids are Effective Inhibitors ofin vitroHemolysis of Human Erythrocytes, as Determined by a Practical and Optimized Cellular Antioxidant Assay

scientific article published on 20 August 2014

Carotenoids inhibit lipid peroxidation and hemoglobin oxidation, but not the depletion of glutathione induced by ROS in human erythrocytes

scientific article published on 28 January 2014

Chalcones as Modulators of Neutrophil Oxidative Burst under Physiological and High Glucose Conditions

scientific article published on 02 October 2020

Chemical characterization and protective effect of the Bactris setosa Mart. fruit against oxidative/nitrosative stress

scientific article published on 30 September 2016

Chemical characterization of a red raspberry fruit extract and evaluation of its pharmacological effects in experimental models of acute inflammation and collagen-induced arthritis.

scientific article published in December 2014

Chlorinated Flavonoids Modulate the Inflammatory Process in Human Blood

scientific article

Colour score as a guide for estimating the protein value of corn gluten feed

article

Combined dual effect of modulation of human neutrophils' oxidative burst and inhibition of colon cancer cells proliferation by hydroxycinnamic acid derivatives

scientific article published on 30 May 2016

Effects of Chrysosporum (Aphanizomenon) ovalisporum extracts containing cylindrospermopsin on growth, photosynthetic capacity, and mineral content of carrots (Daucus carota)

scholarly article by Remedios Guzmán-Guillén et al published 21 October 2016 in Ecotoxicology

Effects of microcystin-LR and cylindrospermopsin on plant-soil systems: A review of their relevance for agricultural plant quality and public health

scientific article

Effects of microcystin-LR, cylindrospermopsin and a microcystin-LR/cylindrospermopsin mixture on growth, oxidative stress and mineral content in lettuce plants ( Lactuca sativa L.)

article

Effects of storage, processing and proteolytic digestion on microcystin-LR concentration in edible clams

scholarly article by Marisa Freitas et al published April 2014 in Food and Chemical Toxicology

Erythropoietin reduces acute lung injury and multiple organ failure/dysfunction associated to a scald-burn inflammatory injury in the rat.

scientific article published in February 2015

Evaluation of a flavonoids library for inhibition of pancreatic α-amylase towards a structure-activity relationship

scientific article published on 01 December 2019

Evaluation of the noise exposure of symphonic orchestra musicians

scientific article

Exposure of Lycopersicon esculentum to microcystin-LR: effects in the leaf proteome and toxin translocation from water to leaves and fruits

scientific article

Flavonoids Inhibit COX-1 and COX-2 Enzymes and Cytokine/Chemokine Production in Human Whole Blood

article

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study

scientific article published on 27 September 2019

Immunomodulatory effects of flavonoids in the prophylaxis and treatment of inflammatory bowel diseases: a comprehensive review

scientific article published on 14 February 2018

Indole based cyclooxygenase inhibitors: synthesis, biological evaluation, docking and NMR screening

scientific article

Infusion, decoction and hydroalcoholic extracts of leaves from artichoke ( Cynara cardunculus L. subsp. cardunculus ) are effective scavengers of physiologically relevant ROS and RNS

scientific article published on 17 June 2014

Inhibition of LOX by flavonoids: a structure-activity relationship study

scientific article

Inhibition of glycogen synthase kinase-3β attenuates organ injury and dysfunction associated with liver ischemia-reperfusion and thermal injury in the rat.

scientific article published in April 2015

Inhibition of protein tyrosine phosphatase 1B by flavonoids: A structure - activity relationship study

scientific article published on 21 November 2017

Interaction of polyacrylic acid coated and non-coated iron oxide nanoparticles with human neutrophils.

scientific article published on 26 November 2013

Isolation and activation of human neutrophils in vitro. The importance of the anticoagulant used during blood collection

scientific article published on 11 January 2008

Lettuce (Lactuca sativa L.) leaf-proteome profiles after exposure to cylindrospermopsin and a microcystin-LR/cylindrospermopsin mixture: a concentration-dependent response.

scientific article

Modulation of human neutrophils' oxidative burst by flavonoids

scientific article published on 21 June 2013

New polyhydroxylated flavon-3-ols and 3-hydroxy-2-styrylchromones: synthesis and ROS/RNS scavenging activities

scientific article published on 25 April 2016

Nickel induces apoptosis in human neutrophils.

scientific article published on 25 October 2012

Nickel induces oxidative burst, NF-κB activation and interleukin-8 production in human neutrophils

scientific article published on 15 July 2010

Novel chromone and xanthone derivatives: Synthesis and ROS/RNS scavenging activities

scientific article published on 21 March 2016

Ochratoxin A activates neutrophils and kills these cells through necrosis, an effect eliminated through its conversion into ochratoxin α.

scientific article published on 2 September 2016

Optical probes for detection and quantification of neutrophils' oxidative burst. A review.

scientific article published on 04 July 2009

Optimization of Experimental Settings for the Assessment of Reactive Oxygen Species Production by Human Blood

scientific article published on 10 January 2019

Optimization of experimental settings for the analysis of human neutrophils oxidative burst in vitro

scientific article

Proinflammatory Pathways: The Modulation by Flavonoids.

scientific article published on 30 April 2015

Protective effects of a blueberry extract in acute inflammation and collagen-induced arthritis in the rat.

scientific article

Protective effects of hydroxytyrosol-supplemented refined olive oil in animal models of acute inflammation and rheumatoid arthritis

article

Psidium cattleianum fruit extracts are efficient in vitro scavengers of physiologically relevant reactive oxygen and nitrogen species.

scientific article published on 22 May 2014

Quantitative histochemistry for macrophage biodistribution on mice liver and spleen after the administration of a pharmacological-relevant dose of polyacrylic acid-coated iron oxide nanoparticles

scientific article published on 6 February 2017

Scavenging of reactive oxygen and nitrogen species by the prodrug sulfasalazine and its metabolites 5-aminosalicylic acid and sulfapyridine.

scientific article published on January 2010

Seasonal dynamics of Microcystis spp. and their toxigenicity as assessed by qPCR in a temperate reservoir

scientific article published on 29 September 2011

Size-dependent cytotoxicity of silver nanoparticles in human neutrophils assessed by multiple analytical approaches

scientific article published on 29 December 2015

Stem bark and flower extracts of Vismia cauliflora are highly effective antioxidants to human blood cells by preventing oxidative burst in neutrophils and oxidative damage in erythrocytes.

scientific article

Synthesis and antioxidant properties of new chromone derivatives.

scientific article published on 3 September 2009

Synthesis of chlorinated flavonoids with anti-inflammatory and pro-apoptotic activities in human neutrophils

scientific article

Systematic review on anti-diabetic properties of chalcones

article

The dipeptidyl peptidase-4 inhibitory effect of flavonoids is hindered in protein rich environments

scientific article published on 23 August 2019

The effect of chalcones on the main sources of reactive species production: possible therapeutic implications in diabetes mellitus

scientific article published on 24 May 2020

The potential of extracts of Caryocar villosum pulp to scavenge reactive oxygen and nitrogen species ⬇️

scientific article published on June 28, 2012

Trihydroxyflavones with antioxidant and anti-inflammatory efficacy

scientific article

Uncovering novel 3-hydroxy-4-pyridinone metal ion complexes with potential anti-inflammatory properties.

scientific article published on 11 November 2015

Valuable Polyphenolic Antioxidants from Wine Vinasses

article by Beatriz Díaz et al published 12 April 2011 in Food and Bioprocess Technology

Zinc activates neutrophils' oxidative burst.

scientific article published on 17 September 2009

Zinc, cadmium and nickel increase the activation of NF-κB and the release of cytokines from THP-1 monocytic cells ⬇️

scientific article published on August 15, 2011

α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study.

scientific article published in December 2017

List of works by Marisa Freitas

2,3-diarylxanthones as strong scavengers of reactive oxygen and nitrogen species: a structure-activity relationship study.

A comprehensive review on xanthone derivatives as α-glucosidase inhibitors

A study towards drug discovery for the management of type 2 diabetes mellitus through inhibition of the carbohydrate-hydrolyzing enzymes α-amylase and α-glucosidase by chalcone derivatives

Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils

Analysis of the use of microcystin-contaminated water in the growth and nutritional quality of the root-vegetable, Daucus carota

Anti-inflammatory Effects of Persimmon (Diospyros kaki L.) in Experimental Rodent Rheumatoid Arthritis

Anti-inflammatory effect of rosmarinic acid and an extract of Rosmarinus officinalis in rat models of local and systemic inflammation

Antioxidant activity of unexplored indole derivatives: Synthesis and screening ⬇️

Antioxidant and pro-oxidant activities of carotenoids and their oxidation products

Application of real-time PCR in the assessment of the toxic cyanobacterium Cylindrospermopsis raciborskii abundance and toxicological potential.

Bioaccessibility and changes on cylindrospermopsin concentration in edible mussels with storage and processing time

Bioactive compounds and scavenging capacity of extracts from different parts of Vismia cauliflora against reactive oxygen and nitrogen species.

Biodistribution of polyacrylic acid-coated iron oxide nanoparticles is associated with proinflammatory activation and liver toxicity

Biological activities of 2-styrylchromones.

Calcium Pathways in Human Neutrophils-The Extended Effects of Thapsigargin and ML-9

Carotenoids are Effective Inhibitors ofin vitroHemolysis of Human Erythrocytes, as Determined by a Practical and Optimized Cellular Antioxidant Assay

Carotenoids inhibit lipid peroxidation and hemoglobin oxidation, but not the depletion of glutathione induced by ROS in human erythrocytes

Chalcones as Modulators of Neutrophil Oxidative Burst under Physiological and High Glucose Conditions

Chemical characterization and protective effect of the Bactris setosa Mart. fruit against oxidative/nitrosative stress

Chemical characterization of a red raspberry fruit extract and evaluation of its pharmacological effects in experimental models of acute inflammation and collagen-induced arthritis.

Chlorinated Flavonoids Modulate the Inflammatory Process in Human Blood

Colour score as a guide for estimating the protein value of corn gluten feed

Combined dual effect of modulation of human neutrophils' oxidative burst and inhibition of colon cancer cells proliferation by hydroxycinnamic acid derivatives

Effects of Chrysosporum (Aphanizomenon) ovalisporum extracts containing cylindrospermopsin on growth, photosynthetic capacity, and mineral content of carrots (Daucus carota)

Effects of microcystin-LR and cylindrospermopsin on plant-soil systems: A review of their relevance for agricultural plant quality and public health

Effects of microcystin-LR, cylindrospermopsin and a microcystin-LR/cylindrospermopsin mixture on growth, oxidative stress and mineral content in lettuce plants ( Lactuca sativa L.)

Effects of storage, processing and proteolytic digestion on microcystin-LR concentration in edible clams

Erythropoietin reduces acute lung injury and multiple organ failure/dysfunction associated to a scald-burn inflammatory injury in the rat.

Evaluation of a flavonoids library for inhibition of pancreatic α-amylase towards a structure-activity relationship

Evaluation of the noise exposure of symphonic orchestra musicians

Exposure of Lycopersicon esculentum to microcystin-LR: effects in the leaf proteome and toxin translocation from water to leaves and fruits

Flavonoids Inhibit COX-1 and COX-2 Enzymes and Cytokine/Chemokine Production in Human Whole Blood

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study

Immunomodulatory effects of flavonoids in the prophylaxis and treatment of inflammatory bowel diseases: a comprehensive review

Indole based cyclooxygenase inhibitors: synthesis, biological evaluation, docking and NMR screening

Infusion, decoction and hydroalcoholic extracts of leaves from artichoke ( Cynara cardunculus L. subsp. cardunculus ) are effective scavengers of physiologically relevant ROS and RNS

Inhibition of LOX by flavonoids: a structure-activity relationship study

Inhibition of glycogen synthase kinase-3β attenuates organ injury and dysfunction associated with liver ischemia-reperfusion and thermal injury in the rat.

Inhibition of protein tyrosine phosphatase 1B by flavonoids: A structure - activity relationship study

Interaction of polyacrylic acid coated and non-coated iron oxide nanoparticles with human neutrophils.

Isolation and activation of human neutrophils in vitro. The importance of the anticoagulant used during blood collection

Lettuce (Lactuca sativa L.) leaf-proteome profiles after exposure to cylindrospermopsin and a microcystin-LR/cylindrospermopsin mixture: a concentration-dependent response.

Modulation of human neutrophils' oxidative burst by flavonoids

New polyhydroxylated flavon-3-ols and 3-hydroxy-2-styrylchromones: synthesis and ROS/RNS scavenging activities

Nickel induces apoptosis in human neutrophils.

Nickel induces oxidative burst, NF-κB activation and interleukin-8 production in human neutrophils

Novel chromone and xanthone derivatives: Synthesis and ROS/RNS scavenging activities

Ochratoxin A activates neutrophils and kills these cells through necrosis, an effect eliminated through its conversion into ochratoxin α.

Optical probes for detection and quantification of neutrophils' oxidative burst. A review.

Optimization of Experimental Settings for the Assessment of Reactive Oxygen Species Production by Human Blood

Optimization of experimental settings for the analysis of human neutrophils oxidative burst in vitro

Proinflammatory Pathways: The Modulation by Flavonoids.

Protective effects of a blueberry extract in acute inflammation and collagen-induced arthritis in the rat.

Protective effects of hydroxytyrosol-supplemented refined olive oil in animal models of acute inflammation and rheumatoid arthritis

Psidium cattleianum fruit extracts are efficient in vitro scavengers of physiologically relevant reactive oxygen and nitrogen species.

Quantitative histochemistry for macrophage biodistribution on mice liver and spleen after the administration of a pharmacological-relevant dose of polyacrylic acid-coated iron oxide nanoparticles

Scavenging of reactive oxygen and nitrogen species by the prodrug sulfasalazine and its metabolites 5-aminosalicylic acid and sulfapyridine.

Seasonal dynamics of Microcystis spp. and their toxigenicity as assessed by qPCR in a temperate reservoir

Size-dependent cytotoxicity of silver nanoparticles in human neutrophils assessed by multiple analytical approaches

Stem bark and flower extracts of Vismia cauliflora are highly effective antioxidants to human blood cells by preventing oxidative burst in neutrophils and oxidative damage in erythrocytes.

Synthesis and antioxidant properties of new chromone derivatives.

Synthesis of chlorinated flavonoids with anti-inflammatory and pro-apoptotic activities in human neutrophils

Systematic review on anti-diabetic properties of chalcones

The dipeptidyl peptidase-4 inhibitory effect of flavonoids is hindered in protein rich environments

The effect of chalcones on the main sources of reactive species production: possible therapeutic implications in diabetes mellitus

The potential of extracts of Caryocar villosum pulp to scavenge reactive oxygen and nitrogen species ⬇️

Trihydroxyflavones with antioxidant and anti-inflammatory efficacy

Uncovering novel 3-hydroxy-4-pyridinone metal ion complexes with potential anti-inflammatory properties.

Valuable Polyphenolic Antioxidants from Wine Vinasses

Zinc activates neutrophils' oxidative burst.

Zinc, cadmium and nickel increase the activation of NF-κB and the release of cytokines from THP-1 monocytic cells ⬇️

α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study.