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List of works by Jussi Pihlajamäki

A liquid chromatography-tandem mass spectrometry analysis of nine cytochrome P450 probe drugs and their corresponding metabolites in human serum and urine

scientific article published on 12 October 2016

A major gene effect on fasting insulin and insulin sensitivity in familial combined hyperlipidemia

scientific article published in October 2001

A population-based study on the prevalence of NASH using scores validated against liver histology

scientific article published on 12 December 2013

Activated polyamine catabolism leads to low cholesterol levels by enhancing bile acid synthesis

scientific article published on 3 December 2009

Adipose tissue INSR splicing in humans associates with fasting insulin level and is regulated by weight loss

scientific article published on 7 November 2013

Adipose tissue TCF7L2 splicing is regulated by weight loss and associates with glucose and fatty acid metabolism

scientific article

Aldose reductase gene polymorphisms and peripheral nerve function in patients with type 2 diabetes

scientific article

Alterations in fatty acid metabolism in response to obesity surgery combined with dietary counseling

scientific article published on 4 September 2017

Association analysis of peroxisome proliferator-activated receptor gamma polymorphisms and late onset Alzheimer's disease in the Finnish population

scientific article published on 21 September 2006

Association of MBOAT7 gene variant with plasma ALT levels in children: the PANIC study.

scientific article published on 13 July 2016

Association of adiponectin level and variants in the adiponectin gene with glucose metabolism, energy expenditure, and cytokines in offspring of type 2 diabetic patients

scientific article published on 26 April 2005

Association of fatty liver index with the risk of incident cardiovascular disease and acute myocardial infarction

scientific article published on 01 September 2018

Association of indices of liver and adipocyte insulin resistance with 19 confirmed susceptibility loci for type 2 diabetes in 6,733 non-diabetic Finnish men.

scientific article published on 12 December 2010

Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.

scientific article published on 04 April 2013

Association of plasma fatty acid composition with plasma irisin levels in normal weight and overweight/obese children.

scientific article published on 25 August 2015

Associations of I148M variant in PNPLA3 gene with plasma ALT levels during 2-year follow-up in normal weight and overweight children: the PANIC Study.

scientific article published on 11 June 2014

Associations of TM6SF2 167K allele with liver enzymes and lipid profile in children: the PANIC Study.

scientific article

Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals.

scientific article

Brown adipose tissue lipid metabolism in morbid obesity: the effect of bariatric surgery-induced weight loss

scientific article

Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver.

scientific article

Changes in Inflammatory Cytokines Are Related to Impaired Glucose Tolerance in Offspring of Type 2 Diabetic Subjects

scientific article published on 01 December 2006

Changes in cytokine levels during acute hyperinsulinemia in offspring of type 2 diabetic subjects

scientific article published on 2 December 2009

Chapter 12 Regulation of PGC-1 in humans with insulin resistance and type 2 diabetes: Functional implications

Cholesterol absorption decreases after Roux-en-Y gastric bypass but not after gastric banding

scientific article published on 16 December 2009

Cholesterol metabolism and non-cholesterol sterol distribution in lipoproteins of type 1 diabetes: The effect of improved glycemic control

scientific article published on 25 September 2006

Cholesterol synthesis prevails over absorption in metabolic syndrome

scientific article published on 23 May 2007

Circulating CXCR5+PD-1+ICOS+ Follicular T Helper Cells Are Increased Close to the Diagnosis of Type 1 Diabetes in Children With Multiple Autoantibodies

scientific article published on 10 October 2016

Codon 54 polymorphism of the human intestinal fatty acid binding protein 2 gene is associated with dyslipidemias but not with insulin resistance in patients with familial combined hyperlipidemia

scientific article published in June 1997

Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study

scientific article

Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes

scientific article published on 12 May 2006

Comparative nontargeted profiling of metabolic changes in tissues and biofluids in high-fat diet-fed Ossabaw pig.

scientific article

Comparison of Communication Channels for Large-Scale Type 2 Diabetes Risk Screening and Intervention Recruitment: Empirical Study

scientific article published on 09 September 2021

Comprehensive Pharmacogenomic Study Reveals an Important Role of UGT1A3 in Montelukast Pharmacokinetics

scientific article published on 23 September 2017

Conjugated bile acids associate with altered rates of glucose and lipid oxidation after Roux-en-Y gastric bypass

scientific article published on September 2012

Cross-linking of sodium caseinate-structured emulsion with transglutaminase alters postprandial metabolic and appetite responses in healthy young individuals

article

DNA methylation in obesity and type 2 diabetes

scientific article published on 30 April 2014

DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk

scientific article published on 05 May 2016

Decreased plasma serotonin and other metabolite changes in healthy adults after consumption of wholegrain rye: an untargeted metabolomics study

scientific article published on 01 June 2019

Desmosterol in human nonalcoholic steatohepatitis

scientific article published on 29 July 2013

Diabetes medication associates with DNA methylation of metformin transporter genes in the human liver

scientific article published on 21 September 2017

Dietary polyunsaturated fatty acids and the Pro12Ala polymorphisms of PPARG regulate serum lipids through divergent pathways: a randomized crossover clinical trial

scientific article published on 7 October 2015

Different regulation of free fatty acid levels and glucose oxidation by the Trp64Arg polymorphism of the beta3-adrenergic receptor gene and the promoter variant (A-3826G) of the uncoupling protein 1 gene in familial combined hyperlipidemia

scientific article published in November 1998

Differential Mitochondrial Gene Expression in Adipose Tissue Following Weight Loss Induced by Diet or Bariatric Surgery

scientific article published on 01 April 2021

Digitally supported program for type 2 diabetes risk identification and risk reduction in real-world setting: protocol for the StopDia model and randomized controlled trial

Diverse associations of 25-hydroxyvitamin D and 1,25-dihydroxy-vitamin D with dyslipidaemias

scientific article published on 10 September 2010

Downregulation of CPPED1 expression improves glucose metabolism in vitro in adipocytes

scientific article published on 12 August 2013

Effect of Bariatric Surgery on Adipose Tissue Glucose Metabolism in Different Depots in Patients With or Without Type 2 Diabetes

scientific article published on 17 December 2015

Effect of Cold Air on Exercise Capacity in COPD

scientific article published on 01 June 1998

Effect of bariatric surgery on liver glucose metabolism in morbidly obese diabetic and non-diabetic patients

scientific article published on 20 September 2013

Effector T Cell Resistance to Suppression and STAT3 Signaling during the Development of Human Type 1 Diabetes

article

Effects of Genetic Variants on Carboxylesterase 1 Gene Expression, and Clopidogrel Pharmacokinetics and Antiplatelet Effects

scientific article published on 8 October 2017

Endothelial function in hypercholesterolemic subjects: Effects of plant stanol and sterol esters

scientific article published on 28 December 2005

Enhanced Eating Competence Is Associated with Improved Diet Quality and Cardiometabolic Profile in Finnish Adults with Increased Risk of Type 2 Diabetes

scientific article published on 11 November 2021

Epigenetic Alterations in Human Liver From Subjects With Type 2 Diabetes in Parallel With Reduced Folate Levels

scientific article

Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver

scientific article published on 2 December 2016

Epigenetic markers associated with metformin response and intolerance in drug-naïve patients with type 2 diabetes

scientific article published on 01 September 2020

Evaluation of the effect of bariatric surgery-induced weight loss on knee gait and cartilage degeneration

scientific article published on 3 November 2017

Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis

scientific article

FADS2 genotype regulates delta-6 desaturase activity and inflammation in human adipose tissue

scientific article

Fasting serum hippuric acid is elevated after bilberry (Vaccinium myrtillus) consumption and associates with improvement of fasting glucose levels and insulin secretion in persons at high risk of developing type 2 diabetes

scientific article published on 29 May 2017

Fatty acid metabolism is altered in non-alcoholic steatohepatitis independent of obesity

scientific article

Fatty acid uptake and blood flow in adipose tissue compartments of morbidly obese subjects with or without type 2 diabetes: effects of bariatric surgery.

scientific article published on 11 April 2017

Framework of the outreach after a school shooting and the students perceptions of the provided support

scientific article

G-250A substitution in promoter of hepatic lipase gene is associated with dyslipidemia and insulin resistance in healthy control subjects and in members of families with familial combined hyperlipidemia

scientific article

Gene dose effect of the DQB1*0201 allele contributes to severity of coeliac disease.

scientific article

Gene-diet interaction of a commonFADS1variant with marine polyunsaturated fatty acids for fatty acid composition in plasma and erythrocytes among men

article

Genetic influences contributing to LDL particle size in familial combined hyperlipidaemia

scientific article published in September 2002

Genetic risk score does not predict the outcome of obesity surgery.

scientific article published in January 2014

Genetics and phenotypic characteristics of autosomal dominant polycystic kidney disease in Finns

scientific article published on 17 March 2005

Genomewide search and association studies in a Finnish celiac disease population: Identification of a novel locus and replication of the HLA and CTLA4 loci

article

Glomerular filtration rate and parathyroid hormone are associated with 1,25-dihydroxyvitamin D in men without chronic kidney disease

scientific article published on 15 November 2011

HLA genotyping is useful in the evaluation of the risk for coeliac disease in the 1st-degree relatives of patients with coeliac disease

scientific article published on 01 November 2006

Haplotypes of PPARGC1A are associated with glucose tolerance, body mass index and insulin sensitivity in offspring of patients with type 2 diabetes

scientific article published on 24 May 2005

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome

scientific article

Hepatic DPP4 DNA Methylation Associates With Fatty Liver.

scientific article published on 10 October 2016

High circulating levels of RBP4 and mRNA levels of aP2, PGC-1alpha and UCP-2 predict improvement in insulin sensitivity following pioglitazone treatment of drug-naïve type 2 diabetic subjects

scientific article published on April 2008

High perceived stress is associated with unfavorable eating behavior in overweight and obese Finns of working age.

scientific article

High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status

scientific article published on 12 March 2014

Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action

scientific article published on 23 February 2017

Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men

scientific article

INTERLEUKIN-6 PROMOTER POLYMORPHISM AND LATE-ONSET ALZHEIMER's DISEASE IN THE FINNISH POPULATION

scientific article published on 01 July 2005

Identification and characterization of a FOXA2-regulated transcriptional enhancer at a type 2 diabetes intronic locus that controls GCKR expression in liver cells

scientific article

Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes

scientific article published on 02 August 2021

Impact of obesity and associated diseases on outcome after laparoscopic cholecystectomy

scientific article published on December 2012

Impaired free fatty acid suppression during hyperinsulinemia is a characteristic finding in familial combined hyperlipidemia, but insulin resistance is observed only in hypertriglyceridemic patients.

scientific article

Impaired insulin-stimulated glucose oxidation and free fatty acid suppression in patients with familial combined hyperlipidemia: a precursor defect for dyslipidemia?

scientific article published in October 1998

Incidence, comorbidities, and mortality in idiopathic normal pressure hydrocephalus

scientific article published on 25 January 2018

Increased Liver Fatty Acid Uptake Is Partly Reversed and Liver Fat Content Normalized After Bariatric Surgery

scientific article published on 20 November 2017

Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study

scientific article

Inflammatory response to dietary linoleic acid depends on FADS1 genotype

scientific article published on 01 January 2019

Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men.

scientific article

Insulin resistance is related to left ventricular hypertrophy in patients with polycystic kidney disease type 1.

scientific article published in June 2003

Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: lessons from the METSIM Study

scientific article published on May 2010

Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease

scientific article published on 23 February 2021

Internet-Based Lifestyle Intervention to Prevent Type 2 Diabetes Through Healthy Habits: Design and 6-Month Usage Results of Randomized Controlled Trial

scientific article published on 11 August 2020

Interorgan cross talk between fatty acid metabolism, tissue inflammation, and FADS2 genotype in humans with obesity

scientific article

Ketone body production is differentially altered in steatosis and non-alcoholic steatohepatitis in obese humans

scientific article published on 20 January 2015

Link between GIP and osteopontin in adipose tissue and insulin resistance

scientific article published on 24 January 2013

Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23

scientific article

Lipoprotein subclass metabolism in nonalcoholic steatohepatitis

scientific article

Liver DNA methylation of FADS2 associates with FADS2 genotypex

MFAP5 is related to obesity-associated adipose tissue and extracellular matrix remodeling and inflammation

scientific article published on 5 June 2015

Markers of cholesterol metabolism as biomarkers in predicting diabetes in the Finnish Diabetes Prevention Study

scientific article published on 28 March 2015

Markers of endothelial dysfunction and low-grade inflammation are associated in the offspring of type 2 diabetic subjects

scientific article published on 08 June 2007

Molecular evaluation of vitamin D responsiveness of healthy young adults

scientific article published on 6 June 2016

Mucosal-associated invariant T cell alterations during the development of human type 1 diabetes

scientific article published on 03 September 2020

Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome

scientific article published on 13 December 2004

Mutations in the cardiac myosin-binding protein C gene are the predominant cause of familial hypertrophic cardiomyopathy in eastern Finland

article

New variants in the glycogen synthase gene (Gln71His, Met416Val) in patients with NIDDM from eastern Finland.

scientific article

Non-cholesterol sterol levels predict hyperglycemia and conversion to type 2 diabetes in Finnish men

scientific article published in 2013

Obstructive sleep apnea: the effect of bariatric surgery after 12 months. A prospective multicenter trial

scientific article published on 12 January 2017

PCSK9 rs11591147 R46L Loss-of-Function Variant Protects Against Liver Damage in Individuals with NAFLD

scientific article published on 22 October 2020

PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans

scientific article

Persistent organic pollutants and non-alcoholic fatty liver disease in morbidly obese patients: a cohort study

scientific article

Plasma IL-1 receptor antagonist levels correlate with the development of non-alcoholic steatohepatitis

scientific article published on 19 November 2015

Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention

scientific article published on 6 December 2016

Plasma fatty acids as predictors of glycaemia and type 2 diabetes

scientific article published on 16 August 2015

Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity

scientific article

Postprandial glucose metabolism and SCFA after consuming wholegrain rye bread and wheat bread enriched with bioprocessed rye bran in individuals with mild gastrointestinal symptoms

scientific article

Prevalence of Obstructive Sleep Apnoea Among Patients Admitted for Bariatric Surgery. A Prospective Multicentre Trial

scientific article published on 11 November 2015

Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice

scientific article published on 16 February 2016

Progression of kidney disease varies between families with defects in the polycystic kidney disease type 1 gene in eastern Finland

scientific article published in January 2003

Promoter polymorphisms -359T/C and -303A/G of the catalytic subunit p110beta gene of human phosphatidylinositol 3-kinase are not associated with insulin secretion or insulin sensitivity in finnish subjects

scientific article

Promoter polymorphisms of the TNF-alpha (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention Study

scientific article published in July 2003

Protein phosphatase 1 regulatory subunit 3B gene variation protects against hepatic fat accumulation and fibrosis in individuals at high risk of nonalcoholic fatty liver disease.

scientific article

Regulation of alternative splicing in human obesity loci

scientific article

Regulation of alternative splicing in obesity and weight loss

scientific article published on 22 April 2013

Reply to "Statin treatment for non-alcoholic steatohepatitis"

scientific article published on 08 October 2015

Response to Brosch et al

scientific article published on March 2012

SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity

scientific article

Serum Plant Sterols Associate with Gallstone Disease Independent of Weight Loss and Non-Alcoholic Fatty Liver Disease

scientific article published on 3 November 2016

Serum adipokines are associated with cholesterol metabolism in the metabolic syndrome

scientific article published on 18 May 2007

Serum aromatic and branched-chain amino acids associated with NASH demonstrate divergent associations with serum lipids

scientific article published on 20 November 2020

Serum interleukin 1 receptor antagonist as an independent marker of non-alcoholic steatohepatitis in humans.

scientific article

Serum, liver and bile sitosterol and sitostanol in obese patients with and without NAFLD.

scientific article published on 20 April 2018

Sex Differences in the Methylome and Transcriptome of the Human Liver and Circulating HDL-Cholesterol Levels

scientific article published on 01 December 2018

Single nucleotide polymorphisms in the peroxisome proliferator-activated receptor delta gene are associated with skeletal muscle glucose uptake

scientific article published in December 2005

Single nucleotide polymorphisms of the MCHR1 gene do not affect metabolism in humans

scientific article

Single nucleotide polymorphisms of the melanocortin-3 receptor gene are associated with substrate oxidation and first-phase insulin secretion in offspring of type 2 diabetic subjects

scientific article published on 27 December 2006

Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance

scientific article

Sleep of professional athletes: Underexploited potential to improve health and performance

scientific article published on 13 May 2016

Sleep-time physiological recovery is associated with eating habits in distressed working-age Finns with overweight: secondary analysis of a randomised controlled trial

Specific collagen XVIII isoforms promote adipose tissue accrual via mechanisms determining adipocyte number and affect fat deposition

scientific article

Statin use and non-alcoholic steatohepatitis in at risk individuals

scientific article

Sulfonylurea receptor 1 gene variants are associated with gestational diabetes and type 2 diabetes but not with altered secretion of insulin

article

Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease

scientific article published on 11 April 2013

The 148 M allele of the PNPLA3 is associated with plasma irisin levels in a population sample of Caucasian children: The PANIC Study

scientific article published on 28 January 2015

The Ala54Thr Polymorphism of the Fatty Acid Binding Protein 2 Gene Does Not Influence Insulin Sensitivity in Finnish Nondiabetic and NIDDM Subjects

article

The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity

scientific article published in February 2003

The G-250A promoter polymorphism of the hepatic lipase gene predicts the conversion from impaired glucose tolerance to type 2 diabetes mellitus: the Finnish Diabetes Prevention Study

scientific article

The K121Q polymorphism of the PC-1 gene is associated with insulin resistance but not with dyslipidemia

scientific article

The Leu7Pro polymorphism of the neuropeptide Y gene regulates free fatty acid metabolism

scientific article published in May 2003

The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent

scientific article published on 2 February 2016

The Pro12A1a substitution in the peroxisome proliferator activated receptor gamma 2 is associated with an insulin-sensitive phenotype in families with familial combined hyperlipidemia and in nondiabetic elderly subjects with dyslipidemia

scientific article published in August 2000

The Pro12Ala polymorphism of the PPAR gamma 2 gene regulates weight from birth to adulthood

scientific article published in February 2004

The Pro12Ala polymorphism of the PPARgamma2 gene is associated with hepatic glucose uptake during hyperinsulinemia in subjects with type 2 diabetes mellitus

scientific article published in April 2009

The Trp64Arg Polymorphism of the 3-Adrenergic Receptor Gene: Lack of association with NIDDM and features of insulin resistance syndrome

article

The Val103Ile polymorphism of melanocortin-4 receptor regulates energy expenditure and weight gain

scientific article

The cardiac beta-myosin heavy chain gene is not the predominant gene for hypertrophic cardiomyopathy in the Finnish population

scientific article published in November 1998

The effect of the -308A allele of the TNF-alpha gene on insulin action is dependent on obesity

scientific article

The effect of the Ala12 allele of the peroxisome proliferator-activated receptor-gamma2 gene on skeletal muscle glucose uptake depends on obesity: a positron emission tomography study

scientific article published on 26 April 2005

The effectiveness and applicability of different lifestyle interventions for enhancing wellbeing: the study design for a randomized controlled trial for persons with metabolic syndrome risk factors and psychological distress

scientific article

The effects of acceptance and commitment therapy on eating behavior and diet delivered through face-to-face contact and a mobile app: a randomized controlled trial

scientific article published on 27 February 2018

The metabolism of plant sterols is disturbed in postmenopausal women with coronary artery disease

scientific article published in March 2009

Thyroid hormone-related regulation of gene expression in human fatty liver

scientific article published on 23 June 2009

Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease

scientific article published in February 2015

Two polymorphisms in the peroxisome proliferator-activated receptor-gamma gene are associated with severe overweight among obese women

scientific article published on 01 October 1999

Visceral Obesity is Associated with High Levels of Serum Squalene*

scientific article published on 01 July 2006

Visfatin is an adipokine, but it is not regulated by thiazolidinediones

scientific article published on 4 January 2006

[Identification and treatment of malnutrition in a hospital patient]

scholarly article by Helena Orell-Kotikangas et al published 2014 in Duodecim; lääketieteellinen aikakauskirja

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