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List of works by Hilkka Soininen

24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial

scientific article published on 30 October 2017

3-year study of donepezil therapy in Alzheimer's disease: effects of early and continuous therapy

scientific article published on 27 February 2006

A 1-year, randomized, placebo-controlled study of donepezil in patients with mild to moderate AD.

scientific article

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

scientific article published on 12 March 2015

A Follow‐Up Study of Age‐Associated Memory Impairment: Neuropsychological Predictors of Dementia ⬇️

scientific article published on September 1, 1995

A Multi-Cohort Study of ApoE ɛ4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease

scientific article published on January 2017

A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer's Disease Diagnosis

scientific article published on 15 October 2015

A blood gene expression biomarker of early Alzheimer's disease

article

A blood gene expression marker of early Alzheimer's disease

scientific article published on January 2013

A comparison between the accuracy of voxel-based morphometry and hippocampal volumetry in Alzheimer's disease

scientific article published in March 2004

A disease state fingerprint for evaluation of Alzheimer's disease

scientific article published in January 2011

A genotype risk score based on Type 2 diabetes risk factors is associated with lower risk for Alzheimer's disease in APOE e4 carriers

scholarly article by Petroula Proitsi et al published July 2011 in Alzheimer's and Dementia

A multi-metabolite analysis of serum by 1H NMR spectroscopy: early systemic signs of Alzheimer's disease

scientific article published on 26 August 2008

A multinational, randomised, 12-week study comparing the effects of donepezil and galantamine in patients with mild to moderate Alzheimer's disease

scientific article

A nutritional approach to ameliorate altered phospholipid metabolism in Alzheimer's disease

scientific article published in January 2014

A post-mortem study of noradrenergic, serotonergic and GABAergic neurons in Alzheimer's disease

scientific article published in March 1988

A voxel based morphometry study on mild cognitive impairment

scientific article

AMP-activated protein kinase: a potential player in Alzheimer's disease

scientific article published on 24 June 2011

APOE and Alzheimer disease: a major gene with semi-dominant inheritance

scientific article

APOE and modulation of Alzheimer's and frontotemporal dementia

scientific article published in February 2004

APOE ε2 allele is associated with larger regional cortical thicknesses and volumes

scientific article published on 15 September 2010

APOE-epsilon4 is associated with less frontal and more medial temporal lobe atrophy in AD.

scientific article published in November 1999

APOE-epsilon4 is associated with weight loss in women with AD: a population-based study

scientific article published in March 2001

APOE4 predicts amyloid-β in cortical brain biopsy but not idiopathic normal pressure hydrocephalus ⬇️

scientific article published on September 6, 2012

Absence of association between an intercellular adhesion molecule 1 gene E469K polymorphism and Alzheimer's disease in Finnish patients

scientific article published in January 2003

AddNeuroMed and ADNI: similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North America

scientific article published in July 2011

Age-related cognitive decline and electroencephalogram slowing in Down's syndrome as a model of Alzheimer's disease

scientific article published in March 1993

Age-related macular degeneration (AMD): Alzheimer's disease in the eye?

scientific article published on January 2011

Aging and spectral analysis of EEG in normal subjects: a link to memory and CSF AChE.

scientific article published in August 1992

Alcohol drinking and cognitive functions: findings from the Cardiovascular Risk Factors Aging and Dementia (CAIDE) Study

scientific article published on 14 December 2006

Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study

scientific article published on 10 August 2004

Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

scientific article published on 24 July 2014

Alpha-synuclein pathology is highly dependent on the case selection

scientific article published in August 2001

Alzheimer pathology of patients carrying apolipoprotein E epsilon 4 allele

scientific article published in July 1995

Alzheimer's Disease and Mild Cognitive Impairment are Associated with Elevated Levels of Isoaspartyl Residues in Blood Plasma Proteins ⬇️

scientific article published on January 1, 2011

Alzheimer's Disease-Related Polymorphisms in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus

scientific article published in January 2017

Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation

article

Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology

scientific article published on 25 April 2014

Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation

scientific article

Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

scientific article published on 21 September 2013

Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation

scientific article

Alzheimer's disease-related plaques in nondemented subjects

scientific article published on 16 April 2014

Alzheimer's disease: a report from the 7th Kuopio Alzheimer symposium

scientific article published on 19 October 2015

Amygdaloid atrophy in frontotemporal dementia and Alzheimer's disease

scientific article published in December 2002

Amyloid beta-protein deposition in skin of patients with dementia

scientific article

Amyloid-β and Tau Dynamics in Human Brain Interstitial Fluid in Patients with Suspected Normal Pressure Hydrocephalus

scientific article

An association between a subset of Finnish late-onset Alzheimer's disease and alpha2-macroglobulin

scientific article

An association study between granulin gene polymorphisms and Alzheimer's disease in Finnish population

scientific article published in July 2009

An association study of 21 potential Alzheimer's disease risk genes in a Finnish population

scientific article published in January 2010

An economic evaluation of donepezil in mild to moderate Alzheimer's disease: results of a 1-year, double-blind, randomized trial

scientific article published in January 2003

Analysis of human tau in cerebrospinal fluid

scientific article published in March 2010

Analysis of regional MRI volumes and thicknesses as predictors of conversion from mild cognitive impairment to Alzheimer's disease

scientific article

Anxiety is related to Alzheimer cerebrospinal fluid markers in subjects with mild cognitive impairment ⬇️

scientific article published on September 7, 2012

Apathy and cortical atrophy in Alzheimer's disease

scientific article published on 27 September 2010

Apolipoprotein E (apoE) levels in brains from Alzheimer disease patients and controls

scientific article published in May 1996

Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease

scientific article (publication date: 6 August 2002)

Apolipoprotein E epsilon4 magnifies lifestyle risks for dementia: a population-based study

scientific article published on 08 February 2008

Apolipoprotein E genotype and amyloid load in Alzheimer disease and control brains

scientific article published in January 1997

Apolipoprotein E genotype and hippocampal asymmetry in Alzheimer's disease: a volumetric MRI study

scientific article published on January 2000

Apolipoprotein E polymorphism and Alzheimer's disease in eastern Finland

scientific article published in February 1995

Apolipoprotein E polymorphism in patients with different neurodegenerative disorders

scientific article published in February 1996

Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort

scientific article

Application of the PredictAD decision support tool to a Danish cohort of patients with Alzheimer's disease and other dementias

scientific article published on 26 October 2013

Application of the PredictAD software tool to predict progression in patients with mild cognitive impairment

scientific article published on 6 December 2012

Aromatase enzyme and Alzheimer's disease.

scientific article

Assessment of beta-amyloid in a frontal cortical brain biopsy specimen and by positron emission tomography with carbon 11-labeled Pittsburgh Compound B.

scientific article published on 11 August 2008

Assessments of the accumulation severities of amyloid beta-protein and hyperphosphorylated tau in the medial temporal cortex of control and Alzheimer's brains

scientific article published on 2 March 2006

Association Between Later Life Lifestyle Factors and Alzheimer's Disease Biomarkers in Non-Demented Individuals: A Longitudinal Descriptive Cohort Study

scientific article

Association analysis of peroxisome proliferator-activated receptor gamma polymorphisms and late onset Alzheimer's disease in the Finnish population

scientific article published on 21 September 2006

Association between Plasma Ceramides and Phosphatidylcholines and Hippocampal Brain Volume in Late Onset Alzheimer's Disease

scientific article

Association between mid- to late life physical fitness and dementia: evidence from the CAIDE study

article

Association between mid-life marital status and cognitive function in later life: population based cohort study

scientific article published on 02 July 2009

Association between white matter hyperintensities and executive decline in mild cognitive impairment is network dependent

scientific article published on 23 August 2010

Association of CYP46 intron 2 polymorphism in Finnish Alzheimer's disease samples and a global scale summary

scientific article published on March 2006

Association of magnetic resonance imaging white matter lesions and cognitive decline in Alzheimer's disease

scholarly article by Margit Mikula et al published July 2013 in Alzheimer's and Dementia

Association of metabolic syndrome with Alzheimer disease: a population-based study

scientific article published in September 2006

Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

scientific article

Associations between serum homocysteine, holotranscobalamin, folate and cognition in the elderly: a longitudinal study

scientific article published on 30 December 2011

Associations of CAIDE Dementia Risk Score with MRI, PIB-PET measures, and cognition

scientific article

Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype

scientific article published on 07 June 2011

Astrogliosis and the ApoE genotype. an immunohistochemical study of postmortem human brain tissue

scientific article

Auditory adaptation is differentially impaired in familial and sporadic Alzheimer's disease

scientific article published in February 2002

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Disease in Two Independent Cohorts

scientific article

Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairment

scientific article

Automatic MRI Quantifying Methods in Behavioral-Variant Frontotemporal Dementia Diagnosis

scientific article published in January 2018

Automatic temporal lobe atrophy assessment in prodromal AD: Data from the DESCRIPA study

scientific article

Baseline Telomere Length and Effects of a Multidomain Lifestyle Intervention on Cognition: The FINGER Randomized Controlled Trial

scientific article published on 29 July 2017

Bepridil decreases Aβ and calcium levels in the thalamus after middle cerebral artery occlusion in rats

scientific article published on November 2012

Beta-amyloid deposition in brains of subjects with diabetes

scientific article

Biomarker validation of a dementia risk prediction score

scientific article published on 01 March 2020

Blood plasma IgG Fc glycans are significantly altered in Alzheimer's disease and progressive mild cognitive impairment

scientific article published on January 2014

Blood-based biomarker discovery using aptamer capture (SOMAscan) platform technology

Both N-methyl-D-aspartate (NMDA) and non-NMDA receptors mediate glutamate-induced cleavage of the cyclin-dependent kinase 5 (cdk5) activator p35 in cultured rat hippocampal neurons

scientific article published in September 2004

Brain amyloid load and its associations with cognition and vascular risk factors in FINGER Study

scientific article

Brain anatomy of persistent violent offenders: more rather than less

scientific article

Brain pathology in three subjects from the same pedigree with presenilin-1 (PSEN1) P264L mutation

scientific article published on 22 October 2009

Brain β-Amyloid and Atrophy in Individuals at Increased Risk of Cognitive Decline

scientific article published on 13 December 2018

Butyrylcholinesterase K variant and apolipoprotein E4 genes do not act in synergy in Finnish late-onset Alzheimer's disease patients ⬇️

scientific article published on June 26, 1998

CALHM1 P86L polymorphism does not alter amyloid-beta or tau in cerebrospinal fluid

scientific article

CERAD Neuropsychological Total Scores Reflect Cortical Thinning in Prodromal Alzheimer's Disease

scientific article published on January 2013

CERAD neuropsychological battery total score in multinational mild cognitive impairment and control populations: the AddNeuroMed study

scientific article published in January 2010

CERAD neuropsychological compound scores are accurate in detecting prodromal alzheimer's disease: a prospective AddNeuroMed study

scientific article published in January 2014

CERAD-neuropsychological battery in screening mild Alzheimer’s disease ⬇️

scientific article published on January 4, 2011

CSF Abeta42 and tau or phosphorylated tau and prediction of progressive mild cognitive impairment

scientific article published in April 2005

CSF Abeta42, Tau and phosphorylated Tau, APOE epsilon4 allele and MCI type in progressive MCI.

scientific article published on 20 March 2006

CSF Abeta42, tau and phosphorylated tau correlate with medial temporal lobe atrophy.

scientific article published in May 2008

CSF beta-endorphin-like immunoreactivity in delirium

scientific article published in April 1989

CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings

scientific article published on 18 April 2012

CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease

scientific article published on 29 September 2006

CSF tau is related to apolipoprotein E genotype in early Alzheimer's disease ⬇️

scientific article published on January 1, 1998

Calbindin-D28K-immunoreactive cells and fibres in the human amygdaloid complex

scientific article published on November 1996

Calretinin-immunoreactive cells and fibers in the human amygdaloid complex

scientific article

Calretinin-immunoreactive terminals make synapses on calbindin D28k-immunoreactive neurons in the lateral nucleus of the human amygdala ⬇️

scientific article published on February 9, 1998

Candidate blood proteome markers of Alzheimer's disease onset and progression: A systematic review and replication study

Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study

scientific article published on January 2014

Cardiorespiratory fitness and brain volumes in men and women in the FINGER study

scientific article published on 6 January 2017

Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants

scientific article published on 6 October 2017

Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus

scientific article

Cerebrospinal fluid concentrations of soluble amyloid beta-protein and apolipoprotein E in patients with Alzheimer's disease: correlations with amyloid load in the brain

scientific article published in February 1996

Cerebrospinal fluid somatostatin correlates with spectral EEG variables and with parietotemporal cognitive dysfunction in Alzheimer patients

scientific article published in February 1988

Cerebrospinal fluid somatostatin in delirium.

scientific article published in August 1989

Cerebrospinal fluid {beta}-amyloid 42 and tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain

scientific article published in March 2009

Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline

scientific article published on 29 December 2017

Changes in absolute power values of EEG spectra in the follow-up of Alzheimer's disease

scientific article published in February 1991

Changes in vascular factors 28 years from midlife and late-life cortical thickness

scientific article published on 15 August 2012

Characterization of a novel transgenic rat carrying human tau with mutation P301L.

scientific article published on 25 January 2010

Cholinergic deficit in Alzheimer's disease: A study based on CSF and autopsy data ⬇️

scientific article published on February 1, 1988

Chronic obstructive pulmonary disease and asthma and the risk of mild cognitive impairment and dementia: a population based CAIDE study

scientific article published in June 2013

Circulating Proteomic Signatures of Chronological Age.

scientific article published on 14 August 2014

Circulating immune complexes in sera from patients with Alzheimer's disease and subjects with age-associated memory impairment

scientific article published in January 1993

Circulating immune complexes in sera from patients with Alzheimer's disease, multi-infarct dementia and Down's syndrome

scientific article published in January 1993

Cleavage of the cyclin-dependent kinase 5 activator p35 to p25 does not induce tau hyperphosphorylation

scientific article published in November 2002

Clinical symptoms and symptom signatures of Alzheimer's disease subgroups

scientific article published in January 2013

Coaccumulation of calcium and beta-amyloid in the thalamus after transient middle cerebral artery occlusion in rats

scientific article

Cognitive Function in an Elderly Population With Persistent Impaired Glucose Tolerance ⬇️

scientific article published on March 1, 1998

Cognitive and Neuropsychiatric Symptom Differences in Early Stages of Alzheimer's Disease: Kuopio ALSOVA Study

scientific article

Cognitive and memory deficits in untreated Parkinson's disease and amyotrophic lateral sclerosis patients: a comparative study

scientific article published in January 1993

Cognitive profile of Alzheimer patients with extrapyramidal signs: a longitudinal study

scientific article published in January 1992

Combination analysis of neuropsychological tests and structural MRI measures in differentiating AD, MCI and control groups--the AddNeuroMed study

scientific article published on 14 August 2009

Combination of biomarkers: PET [18F]flutemetamol imaging and structural MRI in dementia and mild cognitive impairment

scientific article published in February 2012

Combinatorial markers of mild cognitive impairment conversion to Alzheimer's disease--cytokines and MRI measures together predict disease progression

scientific article published in January 2011

Combined risk effects of IDE and NEP gene variants on Alzheimer disease

scientific article published in November 2009

Combining transcranial magnetic stimulation and electroencephalography may contribute to assess the severity of Alzheimer's disease

scientific article published on 15 May 2011

Common genetic variants influence human subcortical brain structures

scientific article

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Comparative MR analysis of the entorhinal cortex and hippocampus in diagnosing Alzheimer disease

scientific article published in January 1999

Comparing predictors of conversion to Alzheimer's disease using the disease state index

scientific article

Computed tomography findings in delirium

scientific article published in April 1989

Computed tomography findings in senile dementia and normal aging

scientific article published on January 1982

Consensus statement on dementia education and training in Europe

scientific article published on February 2010

Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice

scientific article published on June 2012

Coronary heart disease and cortical thickness, gray matter and white matter lesion volumes on MRI

scientific article

Correction to: Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline.

scientific article

Correction: Feelings of Hopelessness in Midlife and Cognitive Health in Later Life: A Prospective Population-Based Cohort Study

scientific article published on 4 November 2015

Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation

scientific article published on 21 October 2019

Cortical brain biopsy in long-term prognostication of 468 patients with possible normal pressure hydrocephalus

scientific article published on 10 February 2012

Cortical thickness analysis to detect progressive mild cognitive impairment: a reference to Alzheimer's disease

scientific article published on 10 November 2009

Cortical thickness in frontotemporal dementia, mild cognitive impairment, and Alzheimer's disease

scientific article published in January 2012

Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking

scientific article

DNA fragmentation, gliosis and histological hallmarks of Alzheimer's disease

scientific article published in December 2000

Data-Driven Differential Diagnosis of Dementia Using Multiclass Disease State Index Classifier.

scientific article

Decline of frontal lobe functions in subjects with age-associated memory impairment

scientific article published on January 1997

Decreased brain creatine levels in elderly apolipoprotein E epsilon 4 carriers

scientific article published in March 2003

Decreased hippocampal volume asymmetry on MRIs in nondemented elderly subjects carrying the apolipoprotein E epsilon 4 allele

scientific article published in February 1995

Decreased plasma C-reactive protein levels in 4 allele carriers

Decreased plasma β-amyloid in the Alzheimer's disease APP A673T variant carriers

scientific article published on 26 May 2017

Decreased somatostatin-like immunoreactivity in cerebral cortex and cerebrospinal fluid in Alzheimer's disease

scientific article published in January 1987

Deep sequencing of the Nicastrin gene in pooled DNA, the identification of genetic variants that affect risk of Alzheimer's disease

scientific article

Delirium among elderly persons admitted to a psychiatric hospital: clinical course during the acute stage and one-year follow-up

scientific article published in June 1989

Delphi definition of the EADC-ADNI Harmonized Protocol for hippocampal segmentation on magnetic resonance

scientific article

Dementia without cholinergic deficit

scientific article published in January 1987

Dementia: Risk prediction models in dementia prevention

scientific article published on 19 May 2015

Designing an Internet-Based Multidomain Intervention for the Prevention of Cardiovascular Disease and Cognitive Impairment in Older Adults: The HATICE Trial

scientific article published in January 2018

Detection of grey matter loss in mild Alzheimer's disease with voxel based morphometry

scientific article published on December 2002

Determinants of costs of care for patients with Alzheimer's disease

scientific article

Development of a Late-Life Dementia Prediction Index with Supervised Machine Learning in the Population-Based CAIDE Study

scientific article published on 14 October 2016

Diabetes mellitus and brain atrophy: a computed tomography study in an elderly population

scientific article published on November 1, 1992

Diagnosis of Alzheimer's disease: MRI of the hippocampus vs delayed recall

scientific article published in January 2000

Diagnostic accuracy of Alzheimer's disease: a neuropathological study

scientific article published in January 1996

Differences in cortical thickness in healthy controls, subjects with mild cognitive impairment, and Alzheimer's disease patients: a longitudinal study

scientific article published in January 2010

Different cholinesterase inhibitor effects on CSF cholinesterases in Alzheimer patients

scientific article

Different error pattern of episodic and semantic memory in Alzheimer's disease and Parkinson's disease with dementia

scientific article published on January 1989

Different multivariate techniques for automated classification of MRI data in Alzheimer's disease and mild cognitive impairment

scientific article

Different patterns of cognitive decline related to normal or deteriorating EEG in a 3-year follow-up study of patients with Alzheimer's disease

scientific article published in April 1991

Differential Associations of IL-4 With Hippocampal Subfields in Mild Cognitive Impairment and Alzheimer's Disease

scholarly article by Virginia Boccardi et al published 2018 in Frontiers in Aging Neuroscience

Differential diagnosis of neurodegenerative diseases using structural MRI data

scientific article

Differential hypometabolism patterns according to mild cognitive impairment subtypes

scientific article published on 6 November 2008

Differential sialylation of serpin A1 in the early diagnosis of Parkinson's disease dementia

scientific article

Diffusion tensor imaging and tract-based spatial statistics in Alzheimer's disease and mild cognitive impairment

scientific article published on 12 November 2009

Discovery and use of efficient biomarkers for objective disease state assessment in Alzheimer's disease

scientific article published on January 1, 2010

Discriminating accuracy of medial temporal lobe volumetry and fMRI in mild cognitive impairment

scientific article published on February 2009

Discrimination of tetrahydroaminoacridine responders by a single dose pharmaco-EEG in patients with Alzheimer's disease

scientific article published in June 1991

Disease State Fingerprint in Frontotemporal Degeneration with Reference to Alzheimer's Disease and Mild Cognitive Impairment ⬇️

scientific article published on January 1, 2013

Distinct and overlapping fMRI activation networks for processing of novel identities and locations of objects

scientific article published in October 2005

Distribution of parvalbumin-, calretinin-, and calbindin-D28k-immunoreactive neurons and fibers in the human entorhinal cortex ⬇️

scientific article published on November 10, 1997

Distribution of parvalbumin-immunoreactive cells and fibers in the human amygdaloid complex

scientific article

Do instrumental activities of daily living predict dementia at 1- and 2-year follow-up? Findings from the Development of Screening guidelines and diagnostic Criteria for Predementia Alzheimer's disease study

scientific article published in December 2011

Does an ACTH derivative (Org 2766) prevent deterioration of EEG in Alzheimer's disease?

scientific article published in June 1986

Dopamine-β-hydroxylase and acetylcholinesterase activities of cerebrospinal fluid in Alzheimer's disease ⬇️

scientific article published on July 1, 1984

Down-Regulation of Ku Autoantigen, DNA-Dependent Protein Kinase, and Poly(ADP-ribose) Polymerase during Cellular Senescence ⬇️

scientific article published on September 29, 1997

Down-regulation of seladin-1 increases BACE1 levels and activity through enhanced GGA3 depletion during apoptosis

scientific article published on 8 October 2009

EEG and computed tomography in the investigation of patients with senile dementia

scientific article

EEG findings in senile dementia and normal aging

scientific article published in January 1982

EEG in diagnostics and follow-up of Alzheimer's disease

scientific article published on January 1, 1992

EEG reactivity correlates with neuropsychological test scores in Down's syndrome

scientific article published in October 1996

Early psychosocial intervention does not delay institutionalization in persons with mild Alzheimer disease and has impact on neither disease progression nor caregivers' well-being: ALSOVA 3-year follow-up

scientific article

Education and dementia: what lies behind the association?

scientific article published in October 2007

Education increases reserve against Alzheimer's disease--evidence from structural MRI analysis

scientific article

Effect of APOE ε4 allele on cortical thicknesses and volumes: the AddNeuroMed study

scientific article published in January 2010

Effect of Cholinergic Stimulation in Early Alzheimers Disease - Functional Imaging During a Recognition Memory Task ⬇️

scientific article published on November 1, 2011

Effect of Six Months of Treatment with V0191 in Patients with Suspected Prodromal Alzheimer's Disease ⬇️

scientific article published on January 1, 2012

Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention: A Subgroup Analysis of a Randomized Clinical Trial

scientific article published on 22 January 2018

Effectiveness of open-label donepezil treatment in patients with Alzheimer's disease discontinuing memantine monotherapy

scientific article published in December 2007

Effects of Alzheimer's Disease-Associated Risk Loci on Amyloid-β Accumulation in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients

scientific article published on 11 October 2016

Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach

scientific article published in January 2015

Effects of NR1H3 genetic variation on the expression of liver X receptor α and the progression of Alzheimer's disease

scientific article

Effects of estradiol on spatial learning, hippocampal cytochrome P450 19, and estrogen alpha and beta mRNA levels in ovariectomized female mice

scientific article published on 2 December 2005

Effects of ubiquilin 1 on the unfolded protein response

scientific article published on 25 October 2008

Electromyographic and nerve conduction findings in a patient with neuromyotonia, normocalcemic tetany and small-cell lung cancer.

scientific article published in April 1980

Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease

scientific article

Emerging role of Alzheimer's disease-associated ubiquilin-1 in protein aggregation

scientific article published on February 2010

Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease

scientific article

Encoding of novel picture pairs activates the perirhinal cortex: an fMRI study

scientific article published in January 2003

Entorhinal cortex thickness predicts cognitive decline in Alzheimer's disease

scientific article published on January 2013

Epilepsy in neuropathologically verified Alzheimer's disease

scientific article published on 16 March 2018

Estradiol and Cognition in the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) Cohort Study

scientific article published on 9 December 2016

Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women

scientific article published in September 2005

Evaluating combinations of diagnostic tests to discriminate different dementia types

scholarly article by Marie Bruun et al published 2018 in Alzheimer's & dementia (Amsterdam, Netherlands)

Evaluation of CSF cystatin C, beta-2-microglobulin, and VGF as diagnostic biomarkers of Alzheimer's disease using SRM

scholarly article by Malcolm A. Ward et al published July 2011 in Alzheimer's and Dementia

Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease.

scientific article published on 13 September 2013

Evidence of the association of BIN1 and PICALM with the AD risk in contrasting European populations

scientific article

Evolution of global and local grey matter atrophy on serial MRI scans during the progression from MCI to AD.

scientific article published in May 2012

Exploring Alzheimer molecular pathology in Down's syndrome cerebrospinal fluid

scientific article published on 27 June 2014

FASTKD2 is associated with memory and hippocampal structure in older adults

scientific article published on 11 November 2014

Familial Aggregation of Alzheimer's Disease and Related Disorders: A Collaborative Re-Analysis of Case-Control Studies ⬇️

scientific article published on January 1, 1991

Familial idiopathic normal pressure hydrocephalus

scientific article published on 25 June 2016

Fast and robust extraction of hippocampus from MR images for diagnostics of Alzheimer's disease

scientific article published on 31 January 2011

Fast and robust multi-atlas segmentation of brain magnetic resonance images

scientific article published on 24 October 2009

Fat intake at midlife and cognitive impairment later in life: a population-based CAIDE study

scientific article published on July 2008

Fat intake at midlife and risk of dementia and Alzheimer's disease: a population-based study

scientific article published on 19 May 2006

Feasibility of radiological markers in idiopathic normal pressure hydrocephalus

scientific article published on 21 July 2015

Feelings of Hopelessness in Midlife and Cognitive Health in Later Life: A Prospective Population-Based Cohort Study

scientific article published on 13 October 2015

Five-class differential diagnostics of neurodegenerative diseases using random undersampling boosting

scientific article

Flanking markers of cystatin c (CST3) gene do not show association with Alzheimer's disease

scientific article published on 17 March 2009

Focal cerebral ischemia in rats alters APP processing and expression of Abeta peptide degrading enzymes in the thalamus.

scientific article published on 5 May 2009

Fragile-X: neuropsychological test performance, CGG triplet repeat lengths, and hippocampal volumes

scientific article published on July 1997

Frontal dysfunction blocks the therapeutic effect of THA on attention in Alzheimer's disease

scientific article published in May 1997

Frontotemporal dementia as a neural system disease

scholarly article by Marina Boccardi et al published January 2005 in Neurobiology of Aging

Future directions in Alzheimer's disease from risk factors to prevention

scientific article (publication date: 15 April 2014)

GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients

scientific article published in January 2013

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Generalizability of the disease state index prediction model for identifying patients progressing from mild cognitive impairment to Alzheimer's disease

scientific article published in January 2015

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals Worldwide

scholarly article published 28 August 2017

Genetic Variation in δ-Opioid Receptor Associates with Increased β- and γ-Secretase Activity in the Late Stages of Alzheimer's Disease

scientific article published in September 2015

Genetic analysis of BDNF and TrkB gene polymorphisms in Alzheimer's disease

scientific article

Genetic analysis of genes involved in amyloid-β degradation and clearance in Alzheimer's disease

scientific article

Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort

scientific article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis

scientific article

Genetic risk factors in Finnish patients with Parkinson's disease

scientific article

Genetic study between SIRT1, PPARD, PGC-1alpha genes and Alzheimer's disease

scientific article published on 30 April 2008

Genetic study evaluating LDLR polymorphisms and Alzheimer's disease

scientific article published on 18 January 2007

Genetic variation in apolipoprotein D and Alzheimer's disease

scientific article published in August 2004

Genetics of brain age suggest an overlap with common brain disorders

article

Genome-wide association analysis identifies common variants associated with measures of disease progression in patients with Alzheimer's disease

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

scientific article (publication date: October 2009)

Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease

scientific article published on 20 March 2012

Genome-wide linkage disequilibrium mapping of late-onset Alzheimer’s disease in Finland ⬇️

scientific article published on November 13, 2001

Glucose intolerance, cognitive impairment and Alzheimer's disease

scientific article published in December 1998

Glutamate-induced changes in the DNA-binding complexes of transcription factor YY1 in cultured hippocampal and cerebellar granule cells

scientific article

Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER)

article

Health-related quality of life in patients with idiopathic normal pressure hydrocephalus

scientific article published on 24 June 2015

Healthy Ageing Through Internet Counselling in the Elderly: the HATICE randomised controlled trial for the prevention of cardiovascular disease and cognitive impairment

scientific article

Healthy Dietary Changes in Midlife Are Associated with Reduced Dementia Risk Later in Life

scientific article published on 03 November 2018

Heart diseases and long-term risk of dementia and Alzheimer's disease: a population-based CAIDE study

scientific article

Heparan sulfate proteoglycan 2 polymorphism in Alzheimer's disease and correlation with neuropathology

scientific article published in December 2003

Heterogeneous patterns of brain atrophy in Alzheimer's disease

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High Risk of Dementia in Ventricular Enlargement with Normal Pressure Hydrocephalus Related Symptoms1.

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High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status

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Hippocampal Plasticity in Alzheimer's Disease ⬇️

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Hippocampal and entorhinal cortex atrophy in frontotemporal dementia and Alzheimer's disease

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Hippocampal atrophy is related to impaired memory, but not frontal functions in non-demented Parkinsonʼs disease patients ⬇️

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Hippocampal atrophy rate using an expectation maximization classifier with a disease-specific prior

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Hippocampal plasticity in Alzheimer's disease: changes in highly polysialylated NCAM immunoreactivity in the hippocampal formation

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Hippocampal volumes in Alzheimer's disease, Parkinson's disease with and without dementia, and in vascular dementia: An MRI study

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Hippocampus in Alzheimer's disease: a 3-year follow-up MRI study

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Homovanillic acid and 5-hydroxyindoleacetic acid levels in cerebrospinal fluid of patients with senile dementia of Alzheimer type

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Hospital admissions, outpatient visits and healthcare costs of community-dwellers with Alzheimer's disease

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Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease

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Hypertension and hypercholesterolaemia as risk factors for Alzheimer's disease: potential for pharmacological intervention

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Hypertension and white matter lesions of the brain

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Identification of a novel 4.6-kb genomic deletion in presenilin-1 gene which results in exclusion of exon 9 in a Finnish early onset Alzheimer's disease family: an Alu core sequence-stimulated recombination?

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Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics

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Imaging diagnostics in early dementia

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Imaging of D2 dopamine receptors of patients with Parkinson's disease using single photon emission computed tomography and iodobenzamide I 123.

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Immuno-PCR-based quantification of multiple phosphorylated tau-epitopes linked to Alzheimer's disease

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Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome

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Impaired mitochondrial energy metabolism in Alzheimer's disease: Impact on pathogenesis via disturbed epigenetic regulation of chromatin landscape

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Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

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Improved classification of Alzheimer's disease data via removal of nuisance variability

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Improved generation of probabilistic atlases for the expectation maximization classification

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Incidence of stroke in people with Alzheimer disease: a national register-based approach

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Incidence, comorbidities, and mortality in idiopathic normal pressure hydrocephalus

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Incident Hip Fractures among Community Dwelling Persons with Alzheimer’s Disease in a Finnish Nationwide Register-Based Cohort ⬇️

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Incident ischaemic heart disease in persons with Alzheimer's disease in a Finnish nationwide exposure-matched cohort

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Increased acetylcholinesterase activity in the CSF of Alzheimer patients carrying apolipoprotein epsilon4 allele.

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Increased aspartate aminotransferase activity in cerebrospinal fluid and Alzheimer's disease ⬇️

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Increased expression of Abeta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology.

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Increased fMRI responses during encoding in mild cognitive impairment

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Increased risk of sensorineural hearing loss and migraine in patients with a rare mitochondrial DNA variant 4336A>G in tRNAGln

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Increased γ-secretase activity in idiopathic normal pressure hydrocephalus patients with β-amyloid pathology

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Inflammatory proteins in plasma are associated with severity of Alzheimer's disease

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Influence of phosphorylation of p35, an activator of cyclin-dependent kinase 5 (cdk5), on the proteolysis of p35.

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Injury markers predict time to dementia in subjects with MCI and amyloid pathology

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Insight, cognition and quality of life in Alzheimer's disease

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Insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population

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Interaction between genetic and environmental risk factors for Alzheimer's disease: a reanalysis of case-control studies

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Interleukin 1 alpha gene polymorphism as a susceptibility factor in Alzheimer's disease and its influence on the extent of histopathological hallmark lesions of Alzheimer's disease

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Interleukin-18 alters protein expressions of neurodegenerative diseases-linked proteins in human SH-SY5Y neuron-like cells

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Interrelationship between the Levels of C9orf72 and Amyloid-β Protein Precursor and Amyloid-β in Human Cells and Brain Samples

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Involvement of ubiquilin-1 transcript variants in protein degradation and accumulation

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Is the presenilin-1 E318G missense mutation a risk factor for Alzheimer's disease?

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Lack of genetic association between PPARG gene polymorphisms and Finnish late-onset Alzheimer's disease

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Late-life cynical distrust, risk of incident dementia, and mortality in a population-based cohort

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Leisure-Time and Occupational Physical Activity in Early and Late Adulthood in Relation to Later Life Physical Functioning

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Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease

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Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia

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Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain

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Linkage disequilibrium in the 13q12 region in Finnish late onset Alzheimer's disease patients

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Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts

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Lipid-lowering treatment is related to decreased risk of dementia: a population-based study (FINRISK).

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Localization of M2 muscarinic receptor protein in parvalbumin and calretinin containing cells of the adult rat entorhinal cortex using two complementary methods

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Long-Term Response to Cholinesterase Inhibitor Treatment Is Related to Functional MRI Response in Alzheimer's Disease

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Longitudinal EEG spectral analysis in early stage of Alzheimer's disease

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Longitudinal Protein Changes in Blood Plasma Associated with the Rate of Cognitive Decline in Alzheimer's Disease

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Longitudinal SPECT study in Alzheimer's disease: relation to apolipoprotein E polymorphism ⬇️

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Longitudinal changes of CSF biomarkers in Alzheimer's disease

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Longitudinal study of cerebrospinal fluid amyloid proteins and apolipoprotein E in patients with probable Alzheimer's disease ⬇️

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Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

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Low prevalence of APP duplications in Swedish and Finnish patients with early-onset Alzheimer's disease

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Lower Counts of Astroglia and Activated Microglia in Patients with Alzheimer's Disease with Regular Use of Non-Steroidal Anti-Inflammatory Drugs

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MPO and APOEepsilon4 polymorphisms interact to increase risk for AD in Finnish males

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MR T2 relaxometry in Alzheimer's disease and age-associated memory impairment

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MR imaging of the hippocampus in normal pressure hydrocephalus: correlations with cortical Alzheimer's disease confirmed by pathologic analysis.

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MR volumetric analysis of the human entorhinal, perirhinal, and temporopolar cortices ⬇️

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MRI measures of Alzheimer's disease and the AddNeuroMed study

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MRI of amygdala fails to diagnose early Alzheimer's disease.

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MRI of hippocampus and entorhinal cortex in mild cognitive impairment: a follow-up study

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MRI of the Hippocampus in Alzheimer’s Disease: Sensitivity, Specificity, and Analysis of the Incorrectly Classified Subjects ⬇️

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MRI volumetry of the hippocampus: the effect of slice thickness on volume formation

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Major decrease in the volume of the entorhinal cortex in patients with Alzheimer's disease carrying the apolipoprotein E epsilon 4 allele ⬇️

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Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairment

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Measuring Global Brain Atrophy with the Brain Volume/Cerebrospinal Fluid Index: Normative Values, Cut-Offs and Clinical Associations

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Metabolome in progression to Alzheimer's disease

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Midlife CAIDE dementia risk score and dementia-related brain changes up to 30 years later on magnetic resonance imaging

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Midlife Work-Related Stress Increases Dementia Risk in Later Life: The CAIDE 30-Year Study

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Midlife and late-life body mass index and late-life dementia: results from a prospective population-based cohort

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Midlife coffee and tea drinking and the risk of late-life dementia: a population-based CAIDE study

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Midlife healthy-diet index and late-life dementia and Alzheimer's disease

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Midlife income, occupation, APOE status, and dementia: a population-based study

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Midlife smoking, apolipoprotein E and risk of dementia and Alzheimer's disease: a population-based cardiovascular risk factors, aging and dementia study

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Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study

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Midlife vascular risk factors and Alzheimer's disease: evidence from epidemiological studies

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Midlife vascular risk factors and late-life mild cognitive impairment: A population-based study

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Midlife work-related stress is associated with late-life cognition

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Mild cognitive impairment associates with concurrent decreases in serum cholesterol and cholesterol-related lipoprotein subclasses

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Mitochondrial DNA polymorphisms as risk factors for Parkinson's disease and Parkinson's disease dementia

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Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood

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Mixed brain pathologies in dementia: the BrainNet Europe consortium experience

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Modifiable lifestyle factors in dementia: a systematic review of longitudinal observational cohort studies

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Modified serpinA1 as risk marker for Parkinson's disease dementia: Analysis of baseline data

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Multi-method analysis of MRI images in early diagnostics of Alzheimer's disease

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Multi-template tensor-based morphometry: application to analysis of Alzheimer's disease

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Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial

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Multimodal analysis to predict shunt surgery outcome of 284 patients with suspected idiopathic normal pressure hydrocephalus

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Neurochemical markers in the cerebrospinal fluid of patients with Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis and normal controls

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Neuroimaging tools to rate regional atrophy, subcortical cerebrovascular disease, and regional cerebral blood flow and metabolism: consensus paper of the EADC.

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Neuropsychiatric symptoms and Quality of Life in patients with very mild and mild Alzheimer's disease ⬇️

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Neurotransmitter changes in Alzheimer's disease: implications to diagnostics and therapy

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New insights into Alzheimer's disease progression: a combined TMS and structural MRI study

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New risk genes for Alzheimer's disease--biomarkers predicting the disease?

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No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease

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No Genetic Overlap Between Circulating Iron Levels and Alzheimer's Disease

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No association between CALHM1 and Alzheimer's disease risk

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No association between high temperature requirement 1 (HTRA1) gene polymorphisms and Alzheimer's disease

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Novel genetic loci associated with hippocampal volume

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Novel genetic loci underlying human intracranial volume identified through genome-wide association

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Nutrient intake and dietary changes during a 2-year multi-domain lifestyle intervention among older adults: secondary analysis of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) randomised controlled t

Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease

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Olfactory identification in non-demented elderly population and in mild cognitive impairment: a comparison of performance in clinical odor identification versus Boston Naming Test

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Oophorectomy, hysterectomy, and risk of Alzheimer's disease: a nationwide case-control study

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Operationalizing protocol differences for EADC-ADNI manual hippocampal segmentation

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Optimizing the diagnosis of early Alzheimer's disease in mild cognitive impairment subjects.

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Overexpression of APP provides neuroprotection in the absence of functional benefit following middle cerebral artery occlusion in rats

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PET amyloid ligand [11C]PIB uptake and cerebrospinal fluid beta-amyloid in mild cognitive impairment

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Parvalbumin-immunoreactive neurons make inhibitory synapses on pyramidal cells in the human amygdala: a light and electron microscopic study

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Patient- and proxy-reported utility in Alzheimer disease using the EuroQoL.

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Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

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Peripheral signatures of the clusterin-DKK neurotoxicity pathway as potential blood-based biomarkers

Phosphorylated eukaryotic translation factor 4E is elevated in Alzheimer brain

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Pitfalls in the quantitative estimation of β-amyloid immunoreactivity in human brain tissue ⬇️

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Plasma based markers of [11C] PiB-PET brain amyloid burden

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Plasma biomarkers of brain atrophy in Alzheimer's disease

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Plasma inflammatory markers correlate with severity in Alzheimer's disease

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Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease.

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Plasma proteins predict conversion to dementia from prodromal disease

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Polymorphisms in neprilysin gene affect the risk of Alzheimer's disease in Finnish patients

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Polymorphisms in the CYP19 gene confer increased risk for Alzheimer disease

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Poor Cognitive Outcome in Shunt-Responsive Idiopathic Normal Pressure Hydrocephalus ⬇️

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Postmenopausal hormone therapy and Alzheimer disease: A prospective cohort study

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Post‐mortem findings in 10 patients with presumed normal‐pressure hydrocephalus and review of the literature ⬇️

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Predicting AD conversion: comparison between prodromal AD guidelines and computer assisted PredictAD tool

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Predicting progression from cognitive impairment to Alzheimer's disease with the Disease State Index

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Predicting progression of Alzheimer's disease using ordinal regression

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Predicting progression to dementia in persons with mild cognitive impairment using cerebrospinal fluid markers

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Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study

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Prediction of Alzheimer disease in subjects with amnestic and nonamnestic MCI.

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Prefrontal volumes in habitually violent subjects with antisocial personality disorder and type 2 alcoholism

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Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aβ

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Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage

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Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study

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Prevalence of ageing-associated cognitive decline in an elderly population

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Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

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Prevalence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group

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Prevalence of mild cognitive impairment: a population-based study in elderly subjects

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Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

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Prevention of Alzheimer's disease: moving backward through the lifespan

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Prognostic polypeptide blood plasma biomarkers of Alzheimer's disease progression

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Progression from mild cognitive impairment to Alzheimer's disease: effects of sex, butyrylcholinesterase genotype, and rivastigmine treatment

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Progression of Alzheimer's disease during a three-year follow-up using the CERAD-NB total score: Kuopio ALSOVA study ⬇️

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Prolonged Latencies of Pattern Reversal Visual Evoked Early Potentials in Alzheimer Disease

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Promoter polymorphism (-491A/T) in the APOE gene of Finnish Alzheimer's disease patients and control individuals

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Protective variant for hippocampal atrophy identified by whole exome sequencing

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Psychopathy and the posterior hippocampus

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Quantitative analysis of occipital EEG in different stages of Alzheimer's disease

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Quantitative evaluation of disease progression in a longitudinal mild cognitive impairment cohort

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Quantitative validation of a visual rating scale for frontal atrophy: associations with clinical status, APOE e4, CSF biomarkers and cognition

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Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness

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Rapidly progressive multifocal leukoencephalopathy with substantial cell-mediated inflammatory response and with cognitive decline of non-Alzheimer type in a 75-year-old female patient

Reactive microglia in aging and dementia: an immunohistochemical study of postmortem human brain tissue

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Recall and recognition memory in patients with Alzheimer's and Parkinson's diseases

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Recent progress in the research of Alzheimer's disease

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Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia

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Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment

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Recruitment and baseline characteristics of participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)-a randomized controlled lifestyle trial

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Reduction of noradrenaline impairs attention and dopamine depletion slows responses in Parkinson's disease ⬇️

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Reelin-immunoreactive Cajal-Retzius cells: the entorhinal cortex in normal aging and Alzheimer's disease

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Reelin-immunoreactivity in the hippocampal formation of 9-month-old wildtype mouse: effects of APP/PS1 genotype and ovariectomy

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Regional cerebral blood flow measured by 99mTc-HMPAO SPECT differs in subgroups of Alzheimer's disease

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Regional distribution of alpha-synuclein pathology in unimpaired aging and Alzheimer disease

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Regulation of key proteins in Alzheimer’s disease molecular pathogenesis by ubiquilin-1

Relation of coronary atherosclerosis and apolipoprotein E genotypes in Alzheimer patients

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Relationship between EEG reactivity and neuropsychological tests in vascular dementia ⬇️

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Relationship between apoE genotype and CSF beta-amyloid (1-42) and tau in patients with probable and definite Alzheimer's disease

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Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models

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Remodeling of neuronal circuitries in human temporal lobe epilepsy: increased expression of highly polysialylated neural cell adhesion molecule in the hippocampus and the entorhinal cortex

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Risk of Alzheimer's disease among users of postmenopausal hormone therapy: A nationwide case-control study

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Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study

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SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.

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SPECT and MRI analysis in Alzheimer's disease: relation to apolipoprotein E epsilon 4 allele

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Safety and tolerability of the γ-secretase inhibitor avagacestat in a phase 2 study of mild to moderate Alzheimer disease

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Seladin-1 transcription is linked to neuronal degeneration in Alzheimer's disease

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Selegiline treatment and the extent of degenerative changes in brain tissue of patients with Alzheimer's disease

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Sensitivity and specificity of medial temporal lobe visual ratings and multivariate regional MRI classification in Alzheimer's disease

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Sensorimotor, Visual, and Auditory Cortical Atrophy in Unverricht-Lundborg Disease Mapped with Cortical Thickness Analysis ⬇️

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Serial EEG in Alzheimer's disease: 3 year follow-up and clinical outcome ⬇️

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Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults

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Serum testosterone levels in males with Alzheimer's disease

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Serum total cholesterol, statins and cognition in non-demented elderly

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Severity of hippocampal atrophy correlates with the prolongation of MRI T2 relaxation time in temporal lobe epilepsy but not in Alzheimer's disease

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Single-domain amnestic mild cognitive impairment identified by cluster analysis predicts Alzheimer's disease in the european prospective DESCRIPA study

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Sleep disturbances and later cognitive status: a multi-centre study

Slow-wave activity in the spectral analysis of the electroencephalogram and volumes of hippocampus in subgroups of Alzheimer's disease patients

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Slow-wave activity in the spectral analysis of the electroencephalogram is associated with cortical dysfunctions in patients with Alzheimer's disease

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Slowing of electroencephalogram and choline acetyltransferase activity in post mortem frontal cortex in definite Alzheimer's disease

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Slowing of the dominant occipital rhythm in electroencephalogram is associated with low concentration of noradrenaline in the thalamus in patients with Alzheimer's disease ⬇️

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Software tool for improved prediction of Alzheimer's disease

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Somatostatin genetic variants modify the risk for Alzheimer's disease among Finnish patients

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Somatostatin-like immunoreactivity in the cerebrospinal fluid of patients with Parkinson's disease and its relation to dementia

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Spectral analysis of EEG in Alzheimer's disease: relation to apolipoprotein E polymorphism

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Stability of graph theoretical measures in structural brain networks in Alzheimer's disease

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Structural MRI in frontotemporal dementia: comparisons between hippocampal volumetry, tensor-based morphometry and voxel-based morphometry

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Structural and functional MRI in mild cognitive impairment

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Structural correlates of early and late onset Alzheimer's disease: voxel based morphometric study

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Structure and function of medial temporal and posteromedial cortices in early Alzheimer’s disease ⬇️

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Study on the association between SOAT1 polymorphisms, Alzheimer's disease risk and the level of CSF biomarkers

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Subfield- and layer-specific changes in parvalbumin, calretinin and calbindin-D28K immunoreactivity in the entorhinal cortex in Alzheimer's disease

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Subgroups of Alzheimer's disease based on cerebrospinal fluid molecular markers

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Subtle Cognitive Impairment and Alzheimer's Disease-Type Pathological Changes in Cerebrospinal Fluid are Common Among Neurologically Healthy Subjects

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Survey of protocols for the manual segmentation of the hippocampus: preparatory steps towards a joint EADC-ADNI harmonized protocol

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Synaptic dysfunction and septin protein family members in neurodegenerative diseases

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Synergistic effect of apolipoprotein E epsilon4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease

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Systems medicine and the integration of bioinformatic tools for the diagnosis of Alzheimer's disease

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THA disrupts mismatch negativity in Alzheimer disease

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Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease

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Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial

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Targeting ubiquilin-1 in Alzheimer's disease

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Tenomodulin variants, APOE and Alzheimer's disease in a Finnish case-control cohort

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Test sequence of CSF and MRI biomarkers for prediction of AD in subjects with MCI.

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Testing for mutations in exon 17 of the beta-amyloid precursor protein gene in Finnish Alzheimer patients and normal subjects

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Tetrahydroaminoacridine improves the recency effect in Alzheimer's disease

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Tetrahydroaminoacridine modulates technetium-99m labelled ethylene dicysteinate retention in Alzheimer's disease measured with single photon emission computed tomography imaging

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The AddNeuroMed framework for multi-centre MRI assessment of Alzheimer's disease: experience from the first 24 months

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The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers

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The CAIDE Dementia Risk Score App: The development of an evidence-based mobile application to predict the risk of dementia

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The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study

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The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: evidence of validity

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The Effect of Age Correction on Multivariate Classification in Alzheimer's Disease, with a Focus on the Characteristics of Incorrectly and Correctly Classified Subjects

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The Effect of a 2-Year Intervention Consisting of Diet, Physical Exercise, Cognitive Training, and Monitoring of Vascular Risk on Chronic Morbidity-the FINGER Randomized Controlled Trial

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The Expression of Transthyretin and Amyloid-β Protein Precursor is Altered in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients

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The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER): study design and progress

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The MRI pattern of frontal and temporal brain atrophy in fronto-temporal dementia

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The Modified Frontal Behavioral Inventory (FBI-mod) for Patients with Frontotemporal Lobar Degeneration, Alzheimer's Disease, and Mild Cognitive Impairment

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The PredictAD project: development of novel biomarkers and analysis software for early diagnosis of the Alzheimer's disease

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The ability of THA treatment to increase cortical alpha waves is related to apolipoprotein E genotype of Alzheimer disease patients

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The association between APOE ε4 and Alzheimer-type dementia among memory clinic patients is confined to those with a higher education. The DESCRIPA Study

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The association study between DHCR24 polymorphisms and Alzheimer's disease

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The cholinergic system and EEG slow waves

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The effect of TOMM40 poly-T repeat lengths on age of onset and cerebrospinal fluid biomarkers in Finnish Alzheimer's disease patients

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The effect of apolipoprotein polymorphism on brain in mild cognitive impairment: a voxel-based morphometric study

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The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume

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The effect of midlife physical activity on structural brain changes in the elderly

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The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

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The genetic architecture of human brainstem structures and their involvement in common brain disorders

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The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology

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The interactive effect of demographic and clinical factors on hippocampal volume: A multicohort study on 1958 cognitively normal individuals

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The interuncal distance in Alzheimer disease and age-associated memory impairment.

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The level of cerebrospinal fluid tau correlates with neurofibrillary tangles in Alzheimerʼs disease ⬇️

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The levels of cdk5 and p35 proteins and tau phosphorylation are reduced during neuronal apoptosis

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The load and distribution of beta-amyloid in brain tissue of patients with Alzheimer's disease

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Three-year follow-up of cerebrospinal fluid tau, beta-amyloid 42 and 40 concentrations in Alzheimer's disease

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Tocopherols and tocotrienols plasma levels are associated with cognitive impairment

Tolerability of ORM-12741 and effects on episodic memory in patients with Alzheimer's disease

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Transcranial magnetic stimulation-evoked EEG/cortical potentials in physiological and pathological aging

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Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models

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Treatment of Alzheimer's disease with a synthetic ACTH 4-9 analog

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Type-2 diabetes and cognitive function in a non-demented population.

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Ubiquilin-1 modulates γ-secretase-mediated ε-site cleavage in neuronal cells

scientific article published on 21 May 2013

Unusual clinical presentation and neuropathology in two subjects with fused‐in sarcoma (FUS) positive inclusions ⬇️

scientific article published on April 26, 2011

Use of amyloid-PET to determine cutpoints for CSF markers: A multicenter study

scientific article published on 14 October 2015

Use of antiepileptic drugs among community-dwelling persons with Alzheimer's disease in Finland

scientific article published in January 2011

Usefulness of repeated presentation of Mini-Mental State Examination as a diagnostic procedure--a population-based study

scientific article published in December 2002

Using the Disease State Fingerprint Tool for Differential Diagnosis of Frontotemporal Dementia and Alzheimer's Disease

scientific article published on May 2016

Validity of dementia and Alzheimer's disease diagnoses in Finnish national registers

scientific article published on 10 July 2013

Verbal fluency activates the left medial temporal lobe: a functional magnetic resonance imaging study

scientific article published in April 2000

Violent persons with schizophrenia and comorbid disorders: a functional magnetic resonance imaging study

scientific article published on 7 February 2007

Visual assessment of medial temporal atrophy on MR films in Alzheimer's disease: comparison with volumetry

scientific article published in February 2005

Visual presentation of novel objects and new spatial arrangements of objects differentially activates the medial temporal lobe subareas in humans

scientific article published in April 2004

Volumes of hippocampus, amygdala and frontal lobe in Alzheimer patients with different apolipoprotein E genotypes

scientific article published in July 1995

Volumes of hippocampus, amygdala and frontal lobes in the MRI-based diagnosis of early Alzheimer's disease: Correlation with memory functions ⬇️

scientific article published on January 1, 1995

Volumes of the Entorhinal and Perirhinal Cortices in Alzheimer’s Disease ⬇️

scientific article published on January 1, 1998

Web-Based Interventions Targeting Cardiovascular Risk Factors in Middle-Aged and Older People: A Systematic Review and Meta-Analysis

scientific article

White matter hyperintensities and medial temporal lobe atrophy in clinical subtypes of mild cognitive impairment: the DESCRIPA study

scientific article published on 18 June 2009

Whole brain atrophy rate predicts progression from MCI to Alzheimer's disease

scientific article published in October 2008

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

article

Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment

scientific article published on 23 April 2013

Wide third ventricle correlates with low choline acetyltransferase activity of the neocortex in Alzheimer patients.

scientific article published in January 1993

Work-related physical activity and the risk of dementia and Alzheimer's disease

scientific article published in September 2007

World Wide Fingers will advance dementia prevention

scientific article published on 16 December 2017

[Genetics of Alzheimer's disease].

scientific article

beta-Amyloid protein immunoreactivity in skin is not a reliable marker of Alzheimer's disease. An autopsy-controlled study

scientific article published in August 1994

cNEUPRO: Novel Biomarkers for Neurodegenerative Diseases

scientific article

iTRAQ and multiple reaction monitoring as proteomic tools for biomarker search in cerebrospinal fluid of patients with Parkinson's disease dementia.

scientific article published in February 2012

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