List of works by Fredrik Karpe

A "futile cycle" induced by thiazolidinediones in human adipose tissue?

scientific article published in July 2003

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

scientific article published on 24 March 2017

A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels

article

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

scientific article

A common variant in the FTO locus is associated with waist-hip ratio in Indian adolescents

scientific article published on 28 February 2013

A decrease in cardiovascular risk factors in healthy 40-year-old Swedish men between 1980-1983 and 1991-1992.

scientific article

A functional polymorphism in the promoter region of the microsomal triglyceride transfer protein (MTP -493G/T) influences lipoprotein phenotype in familial hypercholesterolemia

scientific article published on 01 July 2000

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice

scientific article

ADRB2 Arg16Gly polymorphism in the LARGE trial

scientific article published in The Lancet

Absence of birth-weight lowering effect of ADCY5 and near CCNL, but association of impaired glucose-insulin homeostasis with ADCY5 in Asian Indians

scientific article

Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway

scientific article published on 01 January 1996

Activation of coagulation factor VII during alimentary lipemia.

scientific article published in January 1994

Activation of peroxisome proliferator-activated receptor (PPAR)delta promotes reversal of multiple metabolic abnormalities, reduces oxidative stress, and increases fatty acid oxidation in moderately obese men.

scientific article

Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 diabetes.

scientific article published on 23 January 2007

Adipose tissue fatty acid metabolism and cardiovascular disease

scientific article

Adipose tissue fatty acid metabolism in insulin-resistant men

scholarly article by A. S. T. Bickerton et al published 1 August 2008 in Diabetologia

Adipose tissue fatty acid metabolism in insulin-resistant men.

scientific article published on 27 May 2008

Adipose tissue function in the insulin-resistance syndrome

scientific article

Adipose tissue: a key target for diabetes pathophysiology and treatment?

scientific article published on October 2007

Alimentary lipemia enhances the membrane expression of platelet P-selectin without affecting other markers of platelet activation

article published in 1998

Alimentary lipemia, postprandial triglyceride-rich lipoproteins, and common carotid intima-media thickness in healthy, middle-aged men.

scientific article published in August 1999

Alterations of VLDL composition during alimentary lipemia.

scientific article published in February 1997

An atlas of G-protein coupled receptor expression and function in human subcutaneous adipose tissue

scientific article published on 19 September 2014

Analysis of the frequency and spectrum of mutations recognised to cause familial hypercholesterolaemia in routine clinical practice in a UK specialist hospital lipid clinic

scientific article published on 18 April 2013

Angiotensin II: a major regulator of subcutaneous adipose tissue blood flow in humans.

scientific article published on 5 January 2006

Apolipoprotein B-48

scientific article published on 01 January 1996

Apolipoprotein M can discriminate HNF1A-MODY from Type 1 diabetes

scientific article

Assessing association between protein truncating variants and quantitative traits

scientific article published on 16 July 2013

Assessment of high-sensitivity C-reactive protein levels as diagnostic discriminator of maturity-onset diabetes of the young due to HNF1A mutations

scientific article

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

scientific article (publication date: November 2010)

Association of adipose tissue blood flow with fat depot sizes and adipokines in women

scientific article published on 26 July 2011

Association of insulin and insulin propeptides with an atherogenic lipoprotein phenotype

scientific article published on 01 November 1995

Association of variants in the fat mass and obesity associated (FTO) gene with polycystic ovary syndrome

scientific article published on 14 May 2008

Associations of Outdoor Temperature, Bright Sunlight, and Cardiometabolic Traits in Two European Population-Based Cohorts.

scientific article published in July 2019

Associations of Variants inFTOand NearMC4RWith Obesity Traits in South Asian Indians

article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Author Correction: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

article

Biology of upper-body and lower-body adipose tissue--link to whole-body phenotypes.

scientific article

Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers

scientific article

Causal Analyses, Statistical Efficiency And Phenotypic Precision Through Recall-By-Genotype Study Design

Changes in adiponectin receptor expression in muscle and adipose tissue of type 2 diabetic patients during rosiglitazone therapy.

scientific article published in July 2005

Chylomicron production as a feature of atherogenic lipoproteins

article

Chylomicron-Derived Fatty Acid Spillover in Adipose Tissue: A Signature of Metabolic Health?

scientific article published in November 2017

Chylomicron/chylomicron remnant turnover in humans: evidence for margination of chylomicrons and poor conversion of larger to smaller chylomicron remnants

scientific article published on 01 May 1997

Circulating MicroRNAs: What Is Their Relevance?

Circulating fibroblast growth factor 21 is induced by peroxisome proliferator-activated receptor agonists but not ketosis in man.

scientific article

Clearance of lipoprotein remnant particles in adipose tissue and muscle in humans

scientific article published on 01 November 1997

Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes

scientific article

Cohort Profile: The Oxford Biobank

scientific article published on 31 July 2017

Common variants near MC4R are associated with fat mass, weight and risk of obesity

scientific article

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

scientific article

Common variation in the gene for apolipoprotein B modulates postprandial lipoprotein metabolism: a hypothesis generating study

scientific article published on July 1995

Comparative protein profiling of serum and plasma using an antibody suspension bead array approach

scientific article published in February 2010

Comparison of regional fat measurements by dual-energy X-ray absorptiometry and conventional anthropometry and their association with markers of diabetes and cardiovascular disease risk

scientific article published on 20 November 2017

Composition of human low density lipoprotein: effects of postprandial triglyceride-rich lipoproteins, lipoprotein lipase, hepatic lipase and cholesteryl ester transfer protein.

scientific article published in January 1993

Comprehensive human adipose tissue mRNA and microRNA endogenous control selection for quantitative real-time-PCR normalization

scientific article

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

scientific article published on 27 July 2009

Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans

scientific article

Coupling of metabolism and cardiovascular responses

article

DNA methylation of genes in adipose tissue.

scientific article published on 14 December 2010

Determinants of VLDL-triglycerides production

scientific article published on August 2012

Determination of apolipoproteins B-48 and B-100 in triglyceride-rich lipoproteins by analytical SDS-PAGE

scientific article published on 01 July 1994

Development of an arterio-venous difference method to study the metabolic physiology of the femoral adipose tissue depot

scientific article published on 7 January 2010

Dietary fat and insulin sensitivity

scientific article published on 25 February 2010

Dietary fatty acids make a rapid and substantial contribution to VLDL-triacylglycerol in the fed state

scientific article published on 07 November 2006

Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma.

scientific article

Differences in partitioning of meal fatty acids into blood lipid fractions: a comparison of linoleate, oleate, and palmitate.

scientific article published on 21 October 2008

Differences in postprandial concentrations of very-low-density lipoprotein and chylomicron remnants between normotriglyceridemic and hypertriglyceridemic men with and without coronary heart disease.

scientific article published in March 1999

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications

scientific article published on 19 June 2014

Distribution of PCB congeners, DDE, hexachlorobenzene, and methylsulfonyl metabolites of PCB and DDE among various fractions of human blood plasma.

scientific article published in October 1999

Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition?

scientific article

Dyslipoproteinemic changes in borderline hypertension

scientific article published on 01 November 1994

Dysregulation of subcutaneous adipose tissue blood flow in overweight postmenopausal women

scientific article published in March 2010

Effects of Peroxisome Proliferator-Activated Receptor-α and -γ Agonists on 11β-Hydroxysteroid Dehydrogenase Type 1 in Subcutaneous Adipose Tissue in Men

scientific article published on 27 February 2007

Effects of a cardioselective beta-blocker on postprandial triglyceride-rich lipoproteins, low density lipoprotein particle size and glucose-insulin homeostasis in middle-aged men with modestly increased cardiovascular risk

scientific article

Effects of acute administration of doxazosin on fasting and postprandial haemodynamics and lipid metabolism in healthy subjects

scientific article published in September 2002

Effects of atorvastatin on postprandial plasma lipoproteins in postinfarction patients with combined hyperlipidaemia

scientific article

Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X(7) receptor antagonist: a prospective genotyping approach

scientific article published on August 2012

Effects of insulin on adipose tissue blood flow in man.

scientific article published in May 2002

Effects of native, triglyceride-enriched, and oxidatively modified LDL on plasminogen activator inhibitor-1 expression in human endothelial cells

Effects of recombinant apolipoprotein A-I(Milano) on aortic atherosclerosis in apolipoprotein E-deficient mice

scientific article published in March 1998

Elevated levels of factor VII activity in the postprandial state: effect of the factor VII Arg-Gln polymorphism

scientific article published on 01 November 1994

Endogenous triglyceride-rich lipoproteins accumulate in rat plasma when competing with a chylomicron-like triglyceride emulsion for a common lipolytic pathway.

scientific article published in July 1995

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

European Lipoprotein Club: Report of the 27th ELC Annual Conference, Tutzing, 6–9 September 2004

European Lipoprotein Club: Report of the 28th ELC Annual Conference, Tutzing, 12–15 September 2005

European Lipoprotein Club: Report of the 29th ELC Annual Conference, Tutzing, 4-7 September 2006.

scientific article published on 3 January 2007

European Lipoprotein Club: Report of the 30th ELC annual conference, Tutzing, 3-6 September 2007.

scientific article published in March 2008

European Lipoprotein Club: report of the 26th ELC Annual Conference, Tutzing, 8-11 September 2003.

scientific article published in March 2004

Exercise prevents the accumulation of triglyceride-rich lipoproteins and their remnants seen when changing to a high-carbohydrate diet

scientific article

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

FTO genetic variants and risk of obesity and type 2 diabetes: a meta-analysis of 28,394 Indians

scientific article published on 20 September 2013

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

scientific article

Failure to increase postprandial blood flow in subcutaneous adipose tissue is associated with tissue resistance to adrenergic stimulation

scientific article published on 23 August 2011

Familial hypercholesterolaemia

scientific article published in the British Medical Journal

Fasted to fed trafficking of Fatty acids in human adipose tissue reveals a novel regulatory step for enhanced fat storage

scientific article published on 17 February 2009

Fatty acid metabolism in patients with PPARgamma mutations

scientific article

Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation

scientific article published on 25 September 2014

Fatty acid-induced mitochondrial uncoupling in adipocytes is not a promising target for treatment of insulin resistance unless adipocyte oxidative capacity is increased.

scientific article published on 21 December 2007

Fatty acids, obesity, and insulin resistance: time for a reevaluation

scientific article

Femoral adipose tissue may accumulate the fat that has been recycled as VLDL and nonesterified fatty acids

scientific article published on 3 August 2010

Functional characterization of 4 polymorphisms in promoter region of hepatic lipase gene

scientific article published on May 2000

Genetic evidence of assortative mating in humans

article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genomics of Adipose Tissue

Ghrelin levels are suppressed and show a blunted response to oral glucose in women with polycystic ovary syndrome

scientific article

Global adiposity rather than abnormal regional fat distribution characterizes women with polycystic ovary syndrome

scientific article

Gluteofemoral adipose tissue plays a major role in production of the lipokine palmitoleate in humans

scientific article

Gluteofemoral body fat as a determinant of metabolic health.

scientific article published on 12 January 2010

Greater dietary fat oxidation in obese compared with lean men: an adaptive mechanism to prevent liver fat accumulation?

scientific article

HDLs and alimentary lipemia. Studies in men with previous myocardial infarction at a young age.

scientific article published in January 1993

Hepatic de novo lipogenesis is suppressed and fat oxidation is increased by omega-3 fatty acids at the expense of glucose metabolism

scientific article published on 01 March 2020

High-density lipoprotein: Relations to metabolic parameters and severity of coronary artery disease

scientific article published on 01 November 1996

Human adipose tissue blood flow and micromanipulation of human subcutaneous blood flow

scientific article published in January 2008

Human intestinal alkaline phosphatase--release to the blood is linked to lipid absorption, but removal from the blood is not linked to lipoprotein clearance

scientific article

Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma

scientific article published in April 2003

Hyperlipidaemia and cardiovascular disease: nonantilipolytic effects of nicotinic acid in adipose tissue

scientific article published on June 2010

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

scientific article

Impaired postprandial adipose tissue blood flow response is related to aspects of insulin sensitivity

scientific article published in August 2002

In vitro and in vivo lipolysis of plasma triglycerides increases the resistance to oxidative modification of low-density lipoproteins

scientific article

In vivo demonstration in humans that large postprandial triglyceride-rich lipoproteins activate coagulation factor VII through the intrinsic coagulation pathway

scientific article published on November 1996

Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis

scientific article published on 03 October 2011

Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men.

scientific article

Influence of dietary fats on pancreatic phospholipids of chronically ethanol-treated rats

scientific article published on 01 September 1988

Insulin and non-esterified fatty acid relations to alimentary lipaemia and plasma concentrations of postprandial triglyceride-rich lipoproteins in healthy middle-aged men.

scientific article published in February 2000

Insulin resistance by adiponectin deficiency: is the action in skeletal muscle?

scientific article published on March 2013

Insulin sensitisation affects lipoprotein lipase transport in type 2 diabetes: role of adipose tissue and skeletal muscle in response to rosiglitazone

article

Integrative physiology of human adipose tissue

scientific article published on 01 August 2003

Interaction between specific fatty acids, GLP-1 and insulin secretion in humans

scientific article published on 02 October 2002

Interactions amongst insulin, lipoproteins and haemostatic function relevant to coronary heart disease.

scientific article published on January 1994

Is there something special about palmitoleate?

scientific article published on March 2013

LDL particle size distribution is associated with carotid intima-media thickness in healthy 50-year-old men.

scientific article published in October 1999

LRP5 regulates human body fat distribution by modulating adipose progenitor biology in a dose- and depot-specific fashion.

scientific article

Lipoprotein lipase in plasma after an oral fat load: relation to free fatty acids

scientific article published on July 1, 1992

Lipoprotein lipase mass and activity in plasma and their increase after heparin are separate parameters with different relations to plasma lipoproteins

scientific article published on 01 August 1995

Lipoprotein lipase transport in plasma: role of muscle and adipose tissues in regulation of plasma lipoprotein lipase concentrations.

scientific article published in December 1998

Lipoprotein metabolism in hepatic lipase deficiency: studies on the turnover of apolipoprotein B and on the effect of hepatic lipase on high density lipoprotein

scientific article

Low frequency and rare coding variation contributes to multiple sclerosis risk

Lower resting and total energy expenditure in postmenopausal compared with premenopausal women matched for abdominal obesity

scientific article

Magnitude of alimentary lipemia is related to intima-media thickness of the common carotid artery in middle-aged men.

scientific article published in December 1998

Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo

scientific article published on 17 August 2012

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Metabolic signatures of human adipose tissue hypoxia in obesity

scientific article published on 28 December 2012

Metabolism of triglyceride-rich lipoproteins during alimentary lipemia

scientific article published on March 1993

MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven

scientific article (publication date: 2011)

MicroRNAs in adipose tissue: their role in adipogenesis and obesity

scientific article published on 24 April 2012

Microsomal triglyceride transfer protein -493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles

scientific article

Monitoring adipose tissue blood flow in man: a comparison between the (133)xenon washout method and microdialysis

scientific article published on 01 January 2002

More than meets the eye: the ACCORD trial and use of statin-fibrate combination in type 2 diabetes mellitus

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

scientific article published on February 2016

Nitric oxide and beta-adrenergic stimulation are major regulators of preprandial and postprandial subcutaneous adipose tissue blood flow in humans

scientific article published on 8 December 2003

Novel experimental protocol to increase specific plasma nonesterified fatty acids in humans

scientific article published on 17 September 2002

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Obesity--On or Off?

scientific article

Oscillations of fatty acid and glycerol release from human subcutaneous adipose tissue in vivo

scientific article published in May 2005

PPARdelta in humans: genetic and pharmacological evidence for a significant metabolic function

scientific article

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

PTEN mutations as a cause of constitutive insulin sensitivity and obesity.

scientific article

Parallel activation of de novo lipogenesis and stearoyl-CoA desaturase activity after 3 d of high-carbohydrate feeding

scientific article published in April 2008

Perioperative insulin and glucose infusion maintains normal insulin sensitivity after surgery.

scientific article

Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men.

scientific article

Physical activity and exercise in the regulation of human adipose tissue physiology

scientific article published on January 2012

Plasma leptin is influenced by diet composition and exercise

article

Plasma tumour necrosis factor-alpha and early carotid atherosclerosis in healthy middle-aged men.

scientific article published in March 2002

Postprandial enrichment of remnant lipoproteins with apoC-I in healthy normolipidemic men with early asymptomatic atherosclerosis

scientific article published in September 2002

Postprandial lipemia--effect of lipid-lowering drugs

scientific article

Postprandial lipoprotein metabolism and atherosclerosis

scientific article published on 01 June 1995

Postprandial lipoprotein metabolism and atherosclerosis.

scientific article

Postprandial lipoproteins and progression of coronary atherosclerosis

scientific article published on 01 March 1994

Postprandial plasma ApoB-48 levels are influenced by a polymorphism in the promoter of the microsomal triglyceride transfer protein gene

scientific article published in February 2002

Preferential uptake of dietary Fatty acids in adipose tissue and muscle in the postprandial period.

scientific article published in January 2007

Prevalence, incidence and predictors of cardiovascular risk factors: longitudinal data from rural and urban South India and comparison with global data

scientific article published on 01 October 2020

Proneness to formation of tight and rigid fibrin gel structures in men with myocardial infarction at a young age

scientific article published on 01 October 1996

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Proteomic analysis of human adipose tissue after rosiglitazone treatment shows coordinated changes to promote glucose uptake

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article

Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry.

scientific article

Quantification of postprandial triglyceride-rich lipoproteins in healthy men by retinyl ester labeling and simultaneous measurement of apolipoproteins B-48 and B-100.

scientific article published in February 1995

RANTES release by human adipose tissue in vivo and evidence for depot-specific differences

scientific article published on 24 February 2009

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Recycling between cortisol and cortisone in human splanchnic, subcutaneous adipose, and skeletal muscle tissues in vivo

scientific article

Reduced oxidation of dietary fat after a short term high-carbohydrate diet

scientific article published in April 2008

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

scientific article published on 9 April 2018

Regional fat depot masses are influenced by protein-coding gene variants

article

Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity

scientific article published on 19 March 2013

Regulation of human metabolism by hypoxia-inducible factor

scientific article

Regulation of human subcutaneous adipose tissue blood flow

scientific article published on 29 October 2013

Regulation of subcutaneous adipose tissue blood flow is related to measures of vascular and autonomic function

scientific article published on 6 July 2010

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition.

scientific article

Relationship of tissue factor pathway inhibitor activity to plasma lipoproteins and myocardial infarction at a young age.

scientific article published in June 1994

Relationships of low density lipoprotein subfractions to angiographically defined coronary artery disease in young survivors of myocardial infarction

scientific article published on 01 September 1991

Relationships of thrombosis and fibrinolysis to atherosclerosis.

scientific article published on October 1994

Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides

scientific article

Remnant-like lipoprotein particle cholesterol concentration and progression of coronary and vein-graft atherosclerosis in response to gemfibrozil treatment

scientific article

Remodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages

scientific article published on 28 January 2008

Removal of triacylglycerols from chylomicrons and VLDL by capillary beds: the basis of lipoprotein remnant formation.

scientific article published on June 2007

Republished review: Triglycerides and atherogenic dyslipidaemia: extending treatment beyond statins in the high-risk cardiovascular patient

scientific article

Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity

scientific article published on November 2016

Response to Janiszewski et al

Risk of Fatal Stroke in Patients With Treated Familial Hypercholesterolemia

scientific article published on 01 January 2003

Role of developmental transcription factors in white, brown and beige adipose tissues.

scientific article

Rosiglitazone decreases postprandial production of acylation stimulating protein in type 2 diabetics

scientific article published on 9 May 2007

Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma

scientific article published in May 2005

Selective partitioning of dietary fatty acids into the VLDL TG pool in the early postprandial period.

scientific article published on 16 August 2003

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Short-term hypocaloric nutrition but not bed rest decrease insulin sensitivity and IGF-I bioavailability in healthy subjects: the importance of glucagon.

scientific article published in November 1997

Structural and functional properties of deep abdominal subcutaneous adipose tissue explain its association with insulin resistance and cardiovascular risk in men.

scientific article published in November 2013

Studies on the lecithin: cholesterol acyltransferase substrate properties of HDL as determined by its subclass distribution analysed by gradient gel electrophoresis

scientific article published in February 1990

Substantial Metabolic Activity of Human Brown Adipose Tissue during Warm Conditions and Cold-Induced Lipolysis of Local Triglycerides.

scientific article

Substrate utilization by the failing human heart by direct quantification using arterio-venous blood sampling.

scientific article published on 21 October 2009

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

scholarly article published 13 July 2017

The antidiabetogenic effect of GLP-1 is maintained during a 7-day treatment period and improves diabetic dyslipoproteinemia in NIDDM patients

scientific article published on November 1996

The contribution of splanchnic fat to VLDL triglyceride is greater in insulin-resistant than insulin-sensitive men and women: studies in the postprandial state.

scientific article

The effects of APOE on brain activity do not simply reflect the risk of Alzheimer's disease.

scientific article published on 12 January 2011

The effects of APOE on the functional architecture of the resting brain

scientific article published on 7 August 2011

The effects of rosiglitazone on fatty acid and triglyceride metabolism in type 2 diabetes

scientific article published on 24 December 2004

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The in vivo effects of the Pro12Ala PPARgamma2 polymorphism on adipose tissue NEFA metabolism: the first use of the Oxford Biobank

scientific article published on 17 December 2005

The microsomal triglyceride transfer protein gene-493T variant lowers cholesterol but increases the risk of coronary heart disease

scientific article

The minor allele of the missense polymorphism Ser251Pro in perilipin 2 (PLIN2) disrupts an α-helix, affects lipolysis, and is associated with reduced plasma triglyceride concentration in humans

scientific article

The nicotinic acid receptor--a new mechanism for an old drug

scientific article published on June 2004

The power of genetic diversity in genome-wide association studies of lipids

The presence of methylation quantitative trait loci indicates a direct genetic influence on the level of DNA methylation in adipose tissue

scientific article

Tissue-specific stable isotope measurements of postprandial lipid metabolism in familial combined hyperlipidaemia.

scientific article published on 26 April 2007

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Transcriptional control of human adipose tissue blood flow

scientific article published on 22 January 2009

Transient triglyceridemia decreases vascular reactivity in young, healthy men without risk factors for coronary heart disease

scientific article published on 01 November 1997

Transient triglyceridemia in healthy normolipidemic men increases cellular processing of large very low density lipoproteins by fibroblasts in vitro.

scientific article published in February 1998

Treatment effects on serum lipoprotein lipids, apolipoproteins and low density lipoprotein particle size and relationships of lipoprotein variables to progression of coronary artery disease in the Bezafibrate Coronary Atherosclerosis Intervention Tr

scientific article published on November 1998

Triglycerides and atherogenic dyslipidaemia: extending treatment beyond statins in the high-risk cardiovascular patient.

scientific article published on March 2011

Upper and lower body adipose tissue function: a direct comparison of fat mobilization in humans.

scientific article published in January 2004

Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study

scientific article published on 22 February 2013

Using a new socioepidemiological questionnaire to analyse associations between intergenerational upward social mobility and body fat distribution: a pilot study with the Oxford BioBank cohort

scientific article published on 03 September 2020

Variants of the microsomal triglyceride transfer protein gene are associated with plasma cholesterol levels and body mass index

scientific article published in January 2002

Vascular Peptide Endothelin-1 Links Fat Accumulation With Alterations of Visceral Adipocyte Lipolysis

scientific article published on 19 November 2007

Very-low-density lipoprotein response element in the promoter region of the human plasminogen activator inhibitor-1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia

article

Weight Gain and Height Growth during Infancy, Childhood, and Adolescence as Predictors of Adult Cardiovascular Risk

scientific article

Whole exome sequencing of familial hypercholesterolaemia patients negative for LDLR/APOB/PCSK9 mutations

scientific article

Why, when and how should hypertriglyceridemia be treated in the high-risk cardiovascular patient?

scientific article published on August 2011

Young women partition fatty acids towards ketone body production rather than VLDL-TAG synthesis, compared with young men.

scientific article published on 21 January 2011

[Can cholesterol lowering treatment have unwanted effects?]

scientific article published on 01 May 1991

[Low cholesterol level--symptom of a disease?]

scientific article published on 01 December 1988