List of works by Rainer Rauramaa

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

scientific article published on 12 March 2015

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A central role for GRB10 in regulation of islet function in man.

scientific article published on 3 April 2014

A common haplotype and the Pro582Ser polymorphism of the hypoxia-inducible factor-1alpha (HIF1A) gene in elite endurance athletes

scientific article published on 18 March 2010

A gene-centric study of common carotid artery remodelling

scientific article published on 23 November 2012

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A priori-defined Mediterranean-like dietary pattern predicts cardiovascular events better in north Europe than in Mediterranean countries

A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima–media thickness)

article

Age, marital status and changes in dietary habits in later life: a 21-year follow-up among Finnish women

scientific article published on 2 April 2012

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

scientific article published in August 2012

Association between a β2-adrenergic receptor polymorphism and elite endurance performance

Asymptomatic ST-segment depression during exercise testing and the risk of sudden cardiac death in middle-aged men: a population-based follow-up study

scientific article published on 23 January 2009

BDNF is a novel marker of cognitive function in ageing women: the DR's EXTRA Study.

scientific article published on 6 September 2008

Bone mineral density, body height, and vitamin D receptor gene polymorphism in middle-aged men.

scientific article published in January 2005

Cardiorespiratory fitness and atrial fibrillation: A population-based follow-up study

scientific article

Cardiorespiratory fitness and brain volumes in men and women in the FINGER study

scientific article published on 6 January 2017

Cardiorespiratory fitness and exercise-induced ST segment depression in assessing the risk of sudden cardiac death in men.

scientific article published on 7 September 2016

Cardiorespiratory fitness and lung cancer risk: A prospective population-based cohort study

scientific article published on 10 March 2015

Cardiorespiratory fitness and metabolic syndrome in older men and women: the dose responses to Exercise Training (DR's EXTRA) study

scientific article

Cardiorespiratory fitness and nonfatalcardiovascular events: A population-based follow-up study.

scientific article published on 2 November 2016

Cardiorespiratory fitness and risk of heart failure: a population-based follow-up study

scientific article

Cardiorespiratory fitness and the risk for stroke in men.

scientific article published on July 2003

Cardiorespiratory fitness and vigorous leisure-time physical activity modify the association of small size at birth with the metabolic syndrome

scientific article published in July 2003

Cardiorespiratory fitness as a feature of metabolic syndrome in older men and women: the Dose-Responses to Exercise Training study (DR's EXTRA).

scientific article published on 10 March 2008

Cardiorespiratory fitness, C-reactive protein and lung cancer risk: A prospective population-based cohort study

scientific article published on 22 May 2015

Cardiorespiratory fitness, lifestyle factors and cancer risk and mortality in Finnish men.

scientific article published on 13 August 2009

Carotid plaque-thickness and common carotid IMT show additive value in cardiovascular risk prediction and reclassification

scientific article published on 19 May 2017

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Cross-sectional analysis of baseline data to identify the major determinants of carotid intima-media thickness in a European population: the IMPROVE study

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Determinants of cardiorespiratory fitness in men aged 42 to 60 years with and without cardiovascular disease.

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Effect of weight loss on cytokine messenger RNA expression in peripheral blood mononuclear cells of obese subjects with the metabolic syndrome

scientific article

Effects of aerobic physical exercise on inflammation and atherosclerosis in men: the DNASCO Study: a six-year randomized, controlled trial

scientific article

Elevated systolic blood pressure during recovery from exercise and the risk of sudden cardiac death

scientific article published in March 2014

Endothelial function in hypercholesterolemic subjects: Effects of plant stanol and sterol esters

scientific article published on 28 December 2005

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Evaluation of informed consent in health research: a questionnaire survey

scientific article

Exercise workload, coronary risk evaluation and the risk of cardiovascular and all-cause death in middle-aged men.

scientific article published in June 2008

Expression of ghrelin gene in peripheral blood mononuclear cells and plasma ghrelin concentrations in patients with metabolic syndrome

scientific article

Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability

scientific article

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications

Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci

scientific article published on 05 May 2020

Genetic evidence of assortative mating in humans

article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

scientific article

Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation

scientific article published on 28 September 2017

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk

scientific article

Increased levels of circulating fatty acids are associated with protective effects against future cardiovascular events in non-diabetics

scientific article published on 13 December 2017

Is informed consent related to success in exercise and diet intervention as evaluated at 12 months? DR's EXTRA study

scientific article

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Leisure-Time and Occupational Physical Activity in Early and Late Adulthood in Relation to Later Life Physical Functioning

scientific article published on 2 June 2016

Leisure-time physical activity, cardiorespiratory fitness and feelings of hopelessness in men

scientific article

Long-Term Change in Cardiorespiratory Fitness in Relation to Atrial Fibrillation and Heart Failure (from the Kuopio Ischemic Heart Disease Risk Factor Study).

scientific article published on 2 February 2018

Long-term Change in Cardiorespiratory Fitness and All-Cause Mortality: A Population-Based Follow-up Study

scientific article published on 18 July 2016

Long-term repeatability of measures of early insulin secretion derived from an intravenous glucose tolerance test and conversion from impaired glucose tolerance to diabetes

scientific article published on January 2008

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

scientific article

Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men

Low levels of leisure-time physical activity and cardiorespiratory fitness predict development of the metabolic syndrome

scientific article published in September 2002

Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease

scientific article

Measurements of Carotid Intima-Media Thickness and of Interadventitia Common Carotid Diameter Improve Prediction of Cardiovascular Events

scholarly article by Damiano Baldassarre et al published October 2012 in Journal of the American College of Cardiology

Metabolic syndrome and the progression of carotid intima-media thickness in elderly women

scientific article published in February 2006

Methods, units and quality requirements for the analysis of haemoglobin A1c in diabetes mellitus

scientific article

Moderators of Maintained Increase in Aerobic Exercise Among Aging Men and Women in a 4-Year Randomized Controlled Trial: The DR's EXTRA Study

scientific article published on 19 January 2015

Multi-Ancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

scientific article published in Nature Communications

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

No Evidence of a Common DNA Variant Profile Specific to World Class Endurance Athletes

scientific article published on 29 January 2016

Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.

scientific article published on 18 June 2018

Oxygen uptake at aerobic threshold is inversely associated with fatal cardiovascular and all-cause mortality events.

scientific article published on 14 August 2017

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Physical workload and risk of early retirement: prospective population-based study among middle-aged men.

scientific article published in October 2002

Plasma IL-5 concentration and subclinical carotid atherosclerosis

scientific article

Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis

scientific article

Plasma lecithin:cholesterol acyltransferase and carotid intima-media thickness in European individuals at high cardiovascular risk

scientific article

Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity

scientific article

Progression of carotid intima-media thickness as predictor of vascular events: results from the IMPROVE study

scientific article published on 3 July 2013

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Recruitment and baseline characteristics of participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)-a randomized controlled lifestyle trial

scientific article

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

scientific article published on 9 April 2018

Sedentary lifestyle and emergence of hopelessness in middle-aged men.

scientific article published in October 2010

Sedentary lifestyle, poor cardiorespiratory fitness, and the metabolic syndrome

scientific article published in August 2003

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Serum 25-Hydroxyvitamin D Concentration in Subclinical Carotid Atherosclerosis

article

Sex hormones, inflammation and the metabolic syndrome: a population-based study

scientific article

Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease

scientific article

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Soluble CD93 Is Involved in Metabolic Dysregulation but Does Not Influence Carotid Intima-Media Thickness

scientific article published on October 2016

Systolic blood pressure during exercise testing and the risk of sudden cardiac death

scientific article published on 4 May 2013

Systolic blood pressure during recovery from exercise and the risk of acute myocardial infarction in middle-aged men.

scientific article published on 8 November 2004

Systolic blood pressure response to exercise testing is related to the risk of acute myocardial infarction in middle-aged men.

scientific article published in June 2006

The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER): study design and progress

scientific article published on 17 January 2013

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The Nordic diet and cognition--The DR's EXTRA Study

scientific article published on 24 June 2015

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The human gene map for performance and health-related fitness phenotypes: the 2001 update

scientific article

The human gene map for performance and health-related fitness phenotypes: the 2002 update

scientific article

The human gene map for performance and health-related fitness phenotypes: the 2003 update

scientific article published in September 2004

The human gene map for performance and health-related fitness phenotypes: the 2004 update

scientific article

The impact of time cost of physical exercise on health outcomes by older adults: the DR's EXTRA Study

scientific article published on 25 April 2012

The predictive value of cardiorespiratory fitness for cardiovascular events in men with various risk profiles: a prospective population-based cohort study

scientific article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained

scientific article

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