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List of works by Niels Grarup

A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure

scientific article published in April 2018

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes

scientific article published on 27 April 2018

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

scientific article published on 10 May 2017

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

scientific article published on 24 March 2017

A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease

scientific article published on September 2015

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

scientific article

A functional IFN-λ4-generating DNA polymorphism could protect older asthmatic women from aeroallergen sensitization and associate with clinical features of asthma

scientific article

A genetic risk score of 45 coronary artery disease risk variants associates with increased risk of myocardial infarction in 6041 Danish individuals.

scientific article published on 16 March 2015

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

scientific article published on 05 September 2010

A genome-wide association study of thyroid stimulating hormone and free thyroxine in Danish children and adolescents

scientific article

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

scientific article published on June 2016

A glycogene mutation map for discovery of diseases of glycosylation

scientific article

A novel rare CUBN variant and three additional genes identified in Europeans with and without diabetes: results from an exome-wide association study of albuminuria

article

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

scientific article published on 01 October 2019

A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads

scientific article

ADAMTS9 Regulates Skeletal Muscle Insulin Sensitivity Through Extracellular Matrix Alterations

scientific article published on 09 January 2019

Abdominal adiposity and cardiometabolic risk factors in children and adolescents: a Mendelian randomization analysis

scientific article published on 01 November 2019

An adult-based insulin resistance genetic risk score associates with insulin resistance, metabolic traits and altered fat distribution in Danish children and adolescents who are overweight or obese

scholarly article by Anne-Sofie Graae et al published August 2018 in Diabetologia

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

scientific article published in August 2012

Association of alcohol consumption with allergic disease and asthma: a multi-centre Mendelian randomization analysis

scientific article published on 30 October 2018

Association of genetic variants previously implicated in coronary artery disease with age at onset of coronary artery disease requiring revascularizations

scientific article published in 2019

Association studies of genetic scores of serum vitamin B12 and folate levels with symptoms of depression and anxiety in two danish population studies

scientific article

Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals

scientific article published on 28 September 2011

Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged D

article by Niels Grarup et al published September 2008 in Diabetes

Associations between birth weight and glucose intolerance in adulthood among Greenlandic Inuit

scientific article published on 06 March 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Associations of genetic determinants of serum vitamin B12 and folate concentrations with hay fever and asthma: a Mendelian randomization meta-analysis.

scientific article

Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease ⬇️

scientific article

Blood pressure levels in male carriers of Arg82Cys in CD300LG

scientific article

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

scholarly article by Elahu G. Sustarsic published in July 2018

Carriers of a VEGFA enhancer polymorphism selectively binding CHOP/DDIT3 are predisposed to increased circulating levels of thyroid-stimulating hormone

scientific article (publication date: 14 September 2016)

Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test

scientific article published on 19 October 2010

Causal relationship between obesity and serum testosterone status in men: A bi-directional mendelian randomization analysis

scientific article

Combined analyses of 20 common obesity susceptibility variants ⬇️

scientific article

Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene–gene interaction

article

Common Type 2 Diabetes Risk Gene Variants Associate with Gestational Diabetes

article

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common variants in LEPR, IL6, AMD1, and NAMPT do not associate with risk of juvenile and childhood obesity in Danes: a case-control study

scientific article published on 11 November 2015

Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses

scientific article published on 16 March 2018

Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites

scientific article published in March 2007

Common variation in oxidative phosphorylation genes is not a major cause of insulin resistance or type 2 diabetes

article

Comparative Analyses of QTLs Influencing Obesity and Metabolic Phenotypes in Pigs and Humans

scientific article (publication date: 2015)

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Diabetic microvascular complications are not associated with two polymorphisms in the GLUT-1 and PC-1 genes regulating glucose metabolism in Caucasian type 1 diabetic patients

scientific article published in August 2001

Discovery of coding genetic variants influencing diabetes-related serum biomarkers and their impact on risk of type 2 diabetes

scientific article published on 19 January 2015

Discovery of novel heart rate-associated loci using the Exome Chip

scientific article

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Do gene variants influencing adult adiposity affect birth weight? A population-based study of 24 loci in 4,744 Danish individuals

scientific article

Dysregulation of a long noncoding RNA reduces leptin leading to a leptin-responsive form of obesity

scientific article published on 06 March 2019

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

scientific article published on 01 June 2019

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization

scientific article

Estimation of allele frequency and association mapping using next-generation sequencing data

scientific article

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

scientific article published on 19 November 2012

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 06 June 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

Exome-wide association study on Albuminuria identifies a novel rare variant in CUBN and additional genes, in 33,985 Europeans with and without diabetes

article

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans

scientific article

FUT2-ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

scientific article

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

scientific article published on 08 October 2018

First Genome-Wide Association Study of Latent Autoimmune Diabetes in Adults Reveals Novel Insights Linking Immune and Metabolic Diabetes

scientific article published on 25 September 2018

Functional and genetic epidemiological characterisation of the FFAR4 (GPR120) p.R270H variant in the Danish population

scientific article published on 11 April 2016

G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans

scientific article published on 26 March 2009

GLP-1 Receptor Agonist Treatment in Morbid Obesity and Type 2 Diabetes Due to Pathogenic Homozygous Melanocortin-4 Receptor Mutation: A Case Report

scientific article published on 21 April 2020

GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal

scientific article published on 30 October 2023

Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry

scientific article

Gene-environment interactions in the pathogenesis of type 2 diabetes and metabolism

scientific article published on July 2007

Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology

scientific article

Genetic Determinants of Weight Loss After Bariatric Surgery

scientific article published on 01 August 2019

Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity

scientific article published on 11 September 2020

Genetic Susceptibility for Childhood BMI has no Impact on Weight Loss Following Lifestyle Intervention in Danish Children

scientific article published on 01 December 2018

Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function

scientific article published on 16 December 2016

Genetic analysis of the estrogen-related receptor α and studies of association with obesity and type 2 diabetes

article

Genetic and phenotypic correlations between surrogate measures of insulin release obtained from OGTT data

scientific article

Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets

scientific article

Genetic determinants of blood pressure traits are associated with carotid arterial thickening and plaque formation in patients with type 2 diabetes

scientific article published on 01 January 2019

Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population

scientific article published on 26 February 2018

Genetic determinants of serum vitamin B12 and their relation to body mass index

scientific article published on 19 December 2016

Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels

scientific article published on 10 February 2017

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genetic investigations of sudden unexpected deaths in infancy using next-generation sequencing of 100 genes associated with cardiac diseases

scientific article published on 9 September 2015

Genetic predisposition to higher body fat yet lower cardiometabolic risk in children and adolescents

scientific article published on 22 July 2019

Genetic risk scores for body fat distribution attenuate weight loss in women during dietary intervention

scientific article published on 16 November 2017

Genetic risk scores link body fat distribution with specific cardiometabolic profiles

scientific article published on 17 June 2016

Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond

scientific article published on 24 May 2014

Genetic variability of the SUR1 promoter in relation to beta-cell function and Type II diabetes mellitus

scientific article published in October 2001

Genetic variant SLC2A2 [corrected] Is associated with risk of cardiovascular disease – assessing the individual and cumulative effect of 46 type 2 diabetes related genetic variants

scientific article

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetics of Type 2 Diabetes: the Power of Isolated Populations

scientific article

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

scientific article published in Nature Communications

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

scientific article published on 7 September 2022

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

scientific article published on 24 November 2015

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

scientific article published on 24 January 2019

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

scientific article published on 28 January 2016

Genome-wide association studies of human adiposity: Zooming in on synapses

scientific article published on 28 September 2015

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

scientific journal article

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide population-based association study of extremely overweight young adults--the GOYA study

scientific article (publication date: 2011)

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

scientific article published on 21 June 2016

Glucose tolerance, insulin sensitivity and insulin release in European non-diabetic carriers of a polymorphism upstream of CDKN2A and CDKN2B.

scientific article published on 14 January 2011

Greenlandic Inuit show genetic signatures of diet and climate adaptation

scientific article

Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

scientific article

Haploinsufficiency of ARHGAP42 is associated with hypertension

scientific article published on 21 March 2019

High Prevalence of Diabetes-Predisposing Variants in MODY Genes Among Danish Women With Gestational Diabetes Mellitus

scientific article published on 27 April 2017

Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1.

scientific article published on 7 August 2011

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes

scientific article published on 28 June 2019

Hypertension genetic risk score is associated with burden of coronary heart disease among patients referred for coronary angiography

scientific article published in PLoS ONE

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

scientific article

Identification of KCNJ15 as a susceptibility gene in Asian patients with type 2 diabetes mellitus

scientific article

Identification of Mislabeled Samples and Sample Mix-ups in Genotype Data Using Barcode Genotypes

scientific article published in 2014

Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders

scientific article published on 24 June 2016

Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes

scientific article

Identification of novel LEPR mutations in Pakistani families with morbid childhood obesity

scholarly article by Robina Khan Niazi et al published 15 November 2018 in BMC Medical Genetics

Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population

Impact of rs361072 in the phosphoinositide 3-kinase p110beta gene on whole-body glucose metabolism and subunit protein expression in skeletal muscle

scientific article

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article

Increased frequency of rare missense PPP1R3B variants among Danish patients with type 2 diabetes

scientific article published in PLoS ONE

Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years

scientific article published on 24 October 2016

Interactions of Lipid Genetic Risk Scores With Estimates of Metabolic Health in a Danish Population

scientific article published on 24 February 2015

Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium

scientific article

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

scientific article published on 12 July 2017

Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining

scientific article published on 10 December 2019

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

scientific article

Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

scientific article

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

MTHFR C677T genotype and cardiovascular risk in a general population without mandatory folic acid fortification

scientific article published on 24 January 2014

MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

scientific article

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Mendelian randomisation study of the associations of vitamin B12 and folate genetic risk scores with blood pressure and fasting serum lipid levels in three Danish population-based studies.

scientific article published on 24 February 2016

Meta-analysis of exome array data identifies six novel genetic loci for lung function

scientific article published on 12 January 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

scientific article

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

scientific article published on 19 October 2015

Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome.

scientific article

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

scientific article published on 13 March 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits

scientific article published on 12 October 2020

Numerous Brugada syndrome-associated genetic variants have no effect on J-point elevation, syncope susceptibility, malignant cardiac arrhythmia, and all-cause mortality

scientific article published on 6 October 2016

PC-1 amino acid variant (K121Q) has no impact on progression of diabetic nephropathy in type 1 diabetic patients

scientific article (publication date: August 2002)

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9

scientific article published on 29 October 2019

Physiologic characterization of type 2 diabetes-related loci

scientific article

Polygenic predisposition to breast cancer and the risk of coronary artery disease

scientific article published on 24 May 2019

Prospective studies exploring the possible impact of an ID3 polymorphism on changes in obesity measures

scientific article published on 14 February 2018

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.

scientific article published on 30 May 2018

Quality of dietary fat and genetic risk of type 2 diabetes: individual participant data meta-analysis

scientific article published on 25 July 2019

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Rare genetic variants previously associated with congenital forms of long QT syndrome have little or no effect on the QT interval

scientific article

Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes

scientific article

Recessive Genome-Wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes

scientific article published on 01 March 2022

Reduced CD300LG mRNA tissue expression, increased intramyocellular lipid content and impaired glucose metabolism in healthy male carriers of Arg82Cys in CD300LG: a novel genometabolic cross-link between CD300LG and common metabolic phenotypes

scientific article

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Replication and meta-analysis of common variants identifies a genome-wide significant locus in migraine.

scientific article published on 7 January 2013

Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

Richness of human gut microbiome correlates with metabolic markers

scientific article (publication date: 29 August 2013)

Screening of 31 genes involved in monogenic forms of obesity in 23 Pakistani probands with early-onset childhood obesity: a case report

scientific article published on 05 September 2019

Selection in Europeans on Fatty Acid Desaturases Associated with Dietary Changes

scientific article

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Sequencing reveals protective and pathogenic effects on development of diabetes of rare GLIS3 variants

scientific article published on 15 August 2019

Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility

scientific article

Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism

scientific article published on 01 June 2020

Studies of association of AGPAT6 variants with type 2 diabetes and related metabolic phenotypes in 12,068 Danes

scientific article

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies

scientific article published on 7 September 2007

Studies of the association of Arg72Pro of tumor suppressor protein p53 with type 2 diabetes in a combined analysis of 55,521 Europeans

scientific article

Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects

scientific article published on 31 October 2006

Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects

scientific article published on 25 July 2006

Studies of the variability of the hepatocyte nuclear factor-1beta (HNF-1beta / TCF2) and the dimerization cofactor of HNF-1 (DcoH / PCBD) genes in relation to type 2 diabetes mellitus and beta-cell function

scientific article

The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects.

scientific article published on 25 March 2008

The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit

scientific article published on 30 November 2016

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes

scientific article

The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation

scientific article (publication date: 2012)

The Polygenic and Monogenic Basis of Blood Traits and Diseases

scientific article published on 01 September 2020

The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample

scientific article

The birth weight lowering C-allele of rs900400 near LEKR1 and CCNL1 associates with elevated insulin release following an oral glucose challenge

scientific article (publication date: 2011)

The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders

scientific article published on 24 January 2020

The diabetogenic VPS13C/C2CD4A/C2CD4B rs7172432 variant impairs glucose-stimulated insulin response in 5,722 non-diabetic Danish individuals

scientific article published on 20 January 2011

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

The power of genetic diversity in genome-wide association studies of lipids

The type 2 diabetes risk allele of TMEM154-rs6813195 associates with decreased beta cell function in a study of 6,486 Danes

scientific article

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

scientific article published on 01 September 2020

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article

Type 2 diabetes risk allele near CENTD2 is associated with decreased glucose-stimulated insulin release

scientific article published on 26 January 2011

Type 2 diabetes risk alleles near ADCY5, CDKAL1 and HHEX-IDE are associated with reduced birthweight.

scientific article

Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort

scientific article published in March 2013

Uncovering the genetic history of the present-day Greenlandic population. ⬇️

scientific article

Underlying genetic models of inheritance in established type 2 diabetes associations

scientific article published on 14 July 2009

Urinary metabolomics reveals glycemic and coffee associated signatures of thyroid function in two population-based cohorts

scientific article

Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease

scientific article

Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study

scientific article

Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

scientific article published on 26 April 2010

Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes

scientific article published on 10 December 2008

Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population

scientific article published on 22 January 2014

Variation in the peroxisome proliferator-activated receptor delta gene in relation to common metabolic traits in 7,495 middle-aged white people

scientific article published on 13 April 2007

What is the contribution of two genetic variants regulating VEGF levels to type 2 diabetes risk and to microvascular complications?

scientific article

Whole-Exome Sequencing of 2,000 Danish Individuals and the Role of Rare Coding Variants in Type 2 Diabetes

Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes

scientific article

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