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List of works by Niels Grarup

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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article
Richness of human gut microbiome correlates with metabolic markers

scientific article (publication date: 29 August 2013)
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

scientific article
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article
The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article
Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

scientific article
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)
Greenlandic Inuit show genetic signatures of diet and climate adaptation

scientific article
Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies

scientific article published on 7 September 2007
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article
Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes

scientific article
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

scientific article
A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

scientific article published on 05 September 2010
Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

scientific article published on 08 October 2018
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

scientific article
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

scientific article published on 19 October 2015
Genome-wide associations for birth weight and correlations with adult disease

scientific article
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article
Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry

scientific article
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

scientific article published on 24 November 2015
PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

scientific article published on 28 November 2016
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016
A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012
Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome.

scientific article
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

scientific journal article
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article
Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes

scientific article
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

scientific article published on February 2016
Common Type 2 Diabetes Risk Gene Variants Associate with Gestational Diabetes

article
Estimation of allele frequency and association mapping using next-generation sequencing data

scientific article
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

scientific article published on 19 November 2012
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017
Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

scientific article published in August 2012
G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans

scientific article published on 26 March 2009
Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond

scientific article published on 24 May 2014
Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged D

article by Niels Grarup et al published September 2008 in Diabetes
Genome-wide population-based association study of extremely overweight young adults--the GOYA study

scientific article (publication date: 2011)
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018
Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

scientific article
Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects

scientific article published on 25 July 2006
Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people

scientific article published on 26 April 2010
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

scientific article
Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017
Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

scientific article published on 28 January 2016
Variants near MC4R are associated with obesity and influence obesity-related quantitative traits in a population of middle-aged people: studies of 14,940 Danes

scientific article published on 10 December 2008

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