List of works by Giulio Maria Pasinetti

A comprehensive database and analysis framework to incorporate multiscale data types and enable integrated analysis of bioactive polyphenols

scientific article

A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis

scientific article

Amyloid precursor protein mRNA encoding the Kunitz protease inhibitor domain is increased by kainic acid-induced seizures in rat hippocampus

scientific article (publication date: December 1992)

An Efficient Synthesis of Deoxyrhapontigenin-3-O-β-D-glucuronide, a Brain-targeted Derivative of Dietary Resveratrol, and its Precursor 4'-O-Me-Resveratrol

scientific article published on 07 May 2019

An Extract of Artemisia dracunculus L. Promotes Psychological Resilience in a Mouse Model of Depression.

scientific article published on 13 May 2018

Anti-aggregation Effects of Phenolic Compounds on α-synuclein

scientific article published on 24 May 2020

Association Between Preoperative Malnutrition and Postoperative Delirium After Hip Fracture Surgery in Older Adults.

scientific article published on 6 March 2017

Autonomic Nervous System Dysfunctions as a Basis for a Predictive Model of Risk of Neurological Disorders in Subjects with Prior History of Traumatic Brain Injury: Implications in Alzheimer's Disease.

scientific article published in December 2016

Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: implications for treatment in Alzheimer's disease

scientific article published on January 2009

Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

scientific article

Carvedilol as a potential novel agent for the treatment of Alzheimer's disease

scientific article

Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics

scientific article

Chemical investigation of commercial grape seed derived products to assess quality and detect adulteration

scientific article published on 26 August 2014

Childhood and adolescent obesity and long-term cognitive consequences during aging.

scientific article published on 26 December 2014

Clusterin (apoJ) Alters the Aggregation of Amyloid β-Peptide (Aβ1-42) and Forms Slowly Sedimenting Aβ Complexes That Cause Oxidative Stress ⬇️

scientific article published on November 1, 1995

Complement C1qB and C4 mRNAs responses to lesioning in rat brain

scientific article published on November 1, 1992

Complement mRNA in the mammalian brain: responses to Alzheimer's disease and experimental brain lesioning

scientific article published on November 1, 1992

Cyclooxygenase (COX)-2 and COX-1 Potentiate β-Amyloid Peptide Generation through Mechanisms That Involve γ-Secretase Activity ⬇️

scientific article published on September 24, 2003

Decortication and striatal mRNA: increases of mRNA for fibronectin, but not of NCAM or alpha-1 tubulin

scientific article published on October 1, 1992

Development and validation of an ultra-high performance liquid chromatography/triple quadrupole mass spectrometry method for analyzing microbial-derived grape polyphenol metabolites

scientific article published on 12 September 2018

Dietary composition modulates brain mass and solubilizable Abeta levels in a mouse model of aggressive Alzheimer's amyloid pathology

scientific article published on 21 October 2009

Dietary polyphenols enhance optogenetic recall of fear memory in hippocampal dentate gyrus granule neuron subpopulations

scholarly article published 2018

Dietary polyphenols promote resilience against sleep deprivation-induced cognitive impairment by activating protein translation.

scientific article published on 27 April 2018

Dietary supplementation with decaffeinated green coffee improves diet-induced insulin resistance and brain energy metabolism in mice

scientific article

Diffuse Disconnectivity in tBi: a resting state fMri anD Dti stuDy ⬇️

scientific article published on March 2012

Disappearance of GAD-mRNA and tyrosine hydroxylase in substantia nigra following striatal ibotenic acid lesions: Evidence for transneuronal regression ⬇️

scientific article published on May 1, 1991

Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity

scientific article

Efficient Chemical Synthesis of (Epi)catechin Glucuronides: Brain-Targeted Metabolites for Treatment of Alzheimer's Disease and Other Neurological Disorders

scientific article published on 12 November 2020

Enzymatic synthesis of substituted epicatechins for bioactivity studies in neurological disorders

scientific article

Epigenetic mechanisms linking diabetes and synaptic impairments

scientific article

Epigenetic modifications by polyphenolic compounds alter gene expression in the hippocampus

article

Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice

scientific article

Erratum. The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure

scientific article published on June 2015

Expression profile of genes associated with antimetastatic gene: nm23-mediated metastasis inhibition in breast carcinoma cells

scientific article published on March 2004

Flavonoids and isoflavonoids: from plant biology to agriculture and neuroscience

scientific article

Glucuronidated Flavonoids in Neurological Protection: Structural Analysis and Approaches for Chemical and Biological Synthesis

scientific article

Glucuronidation of Methylated Quercetin Derivatives: Chemical and Biochemical Approaches

scientific article published on 08 December 2020

Grape Derived Polyphenols Attenuate Tau Neuropathology in a Mouse Model of Alzheimer's Disease ⬇️

scientific article published on January 1, 2010

Grape seed polyphenolic extract specifically decreases aβ*56 in the brains of Tg2576 mice

scientific article

Grape-Derived Polyphenols Ameliorate Stress-Induced Depression by Regulating Synaptic Plasticity

scientific article published on 26 September 2019

Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease

scientific article

Grape-seed polyphenolic extract improves the eye phenotype in a Drosophila model of tauopathy

scientific article

IVIG immunotherapy protects against synaptic dysfunction in Alzheimer's disease through complement anaphylatoxin C5a-mediated AMPA-CREB-C/EBP signaling pathway

scientific article published in August 2013

Identification of G-protein coupled receptor kinase 2 in paired helical filaments and neurofibrillary tangles

scientific article published in December 2006

Identification of antihypertensive drugs which inhibit amyloid-beta protein oligomerization

scientific article published in January 2009

Increased neuronal injury in transgenic mice with neuronal overexpression of human cyclooxygenase-2 is reversed by hypothermia and rofecoxib treatment

scientific article published in November 2007

Influence of diabetes on plasma pharmacokinetics and brain bioavailability of grape polyphenols and their phase II metabolites in the Zucker diabetic fatty rat.

scientific article published in June 2017

Inhibiting amyloid β-protein assembly: Size-activity relationships among grape seed-derived polyphenols

scientific article published on 30 July 2015

Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction

scientific article published on 11 April 2006

Investigation of nebivolol as a novel therapeutic agent for the treatment of Alzheimer's disease

scientific article published in January 2013

Is there a future for cyclo-oxygenase inhibitors in Alzheimer's disease?

scientific article

Molecular and Morphological Correlates Following Neuronal Deafferentation: A Cortico-Striatal Model ⬇️

scientific article published on January 1, 1991

Molecular topology as novel strategy for discovery of drugs with aβ lowering and anti-aggregation dual activities for Alzheimer's disease

scientific article published in 2014

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

scientific article

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

scientific article published on 9 January 2013

Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice

scientific article

PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia

scientific article

POTENTIAL APPLICATION OF GRAPE DERIVED POLYPHENOLS IN HUNTINGTON'S DISEASE

scientific article

Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes

scientific article

Peroxisome Proliferator Activator Receptor Gamma Coactivator-1α Overexpression in Amyotrophic Lateral Sclerosis: A Tale of Two Transgenics

scientific article published on 13 May 2020

Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

scientific article

Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease

scientific article

Principles of inflammasome priming and inhibition: Implications for psychiatric disorders

scientific article published on 11 June 2018

Prophylactic effect of flavanol rich preparation metabolites in promoting resilience to a mouse model of social stress

scientific article published on 09 June 2020

Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer's disease-type beta-amyloid neuropathological mechanisms

scientific article published on 2 November 2017

Recommendations for Development of Botanical Polyphenols as "Natural Drugs" for Promotion of Resilience Against Stress-Induced Depression and Cognitive Impairment

scientific article

Recommendations for Development of New Standardized Forms of Cocoa Breeds and Cocoa Extract Processing for the Prevention of Alzheimer's Disease: Role of Cocoa in Promotion of Cognitive Resilience and Healthy Brain Aging

scientific article

Role of complement systems in IVIG mediated attenuation of cognitive deterioration in Alzheimer's disease

scientific article published on January 2014

Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization.

scientific article

Role of standardized grape polyphenol preparation as a novel treatment to improve synaptic plasticity through attenuation of features of metabolic syndrome in a mouse model

scientific article

S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10

scientific article

SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer's disease amyloidosis and improves synaptic function

scientific article published on 29 October 2010

Select non-coding RNA in blood components provide novel clinically accessible biological surrogates for improved identification of traumatic brain injury in OEF/OIF Veterans.

scientific article

Selective brain penetrable Nurr1 transactivator for treating Parkinson's disease

scientific article published on 04 February 2016

Simultaneous bilateral femoral neck fracture and end-stage renal disease in a 76-year-old woman: a case report

scientific article

Striatal responses to decortication. I. Dopaminergic and astrocytic activities ⬇️

scientific article published on December 20, 1991

Suppression of Presymptomatic Oxidative Stress and Inflammation in Neurodegeneration by Grape-Derived Polyphenols

scholarly article by Francis Herman et al published 2018 in Frontiers in Pharmacology

Synthesis and quantitative analysis of plasma-targeted metabolites of catechin and epicatechin

scientific article published on 20 February 2015

Systems biology in the study of neurological disorders: focus on Alzheimer's disease

scientific article published on January 2008

Targeted analysis of microbial-generated phenolic acid metabolites derived from grape flavanols by gas chromatography-triple quadrupole mass spectrometry

scientific article published on 20 June 2018

Targeting multiple pathogenic mechanisms with polyphenols for the treatment of Alzheimer's disease-experimental approach and therapeutic implications

scientific article

The NLRP3 Inflammasome as a Critical Actor in the Inflammaging Process

scientific article published on 26 June 2020

The Use of Antimicrobial and Antiviral Drugs in Alzheimer's Disease

scientific article published on 12 July 2020

The Viral Hypothesis in Alzheimer's Disease: Novel Insights and Pathogen-Based Biomarkers

scientific article published on 29 July 2020

The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans

scientific article published on 27 June 2017

The gut microbiota composition affects dietary polyphenols-mediated cognitive resilience in mice by modulating the bioavailability of phenolic acids

article

Transgenic neuronal expression of proopiomelanocortin attenuates hyperphagic response to fasting and reverses metabolic impairments in leptin-deficient obese mice

scientific article published in November 2003

Unintended effects of cardiovascular drugs on the pathogenesis of Alzheimer's disease

scientific article

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