List of works - Jan Potempa

Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-α and interleukin-1β but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gi

scientific article

Gingival fibromatosis: clinical, molecular and therapeutic issues

scientific article

Epigenetic regulation in bacterial infections: targeting histone deacetylases

scientific article published on 3 October 2017

The Clostridium ramosum IgA proteinase represents a novel type of metalloendopeptidase

scientific article published on 28 January 2002

Development of loop-mediated isothermal amplification assay for detection of human coronavirus-NL63

article

Prostaphopain B structure: a comparison of proregion-mediated and staphostatin-mediated protease inhibition

scientific article published on November 2004

Proteolytic inactivation of alpha-1-anti-chymotrypsin. Sites of cleavage and generation of chemotactic activity

scientific article published on November 15, 1991

A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement System

scientific article

Concentration of antibodies against Porphyromonas gingivalis is increased before the onset of symptoms of rheumatoid arthritis

scientific article published on 07 September 2016

Mirolase, a novel subtilisin-like serine protease from the periodontopathogen Tannerella forsythia

scientific article

Prevalence of genes encoding extracellular proteases in Staphylococcus aureus - important targets triggering immune response in vivo.

scientific article

Noncanonical activation of β-catenin by Porphyromonas gingivalis

scientific article published in June 2015

Citrullination as a plausible link to periodontitis, rheumatoid arthritis, atherosclerosis and Alzheimer’s disease.

scientific article

Inhibition of distant caspase homologues by natural caspase inhibitors

scientific article

Ribonucleotide reductase class III, an essential enzyme for the anaerobic growth of Staphylococcus aureus, is a virulence determinant in septic arthritis

scientific article published on 25 May 2007

Thrombin-activable fibrinolysis inhibitor (TAFI) zymogen is an active carboxypeptidase

scientific article published on 30 November 2006

Serpin alpha 1proteinase inhibitor probed by intrinsic tryptophan fluorescence spectroscopy

scientific article

Staphylococcus aureus proteases degrade lung surfactant protein A potentially impairing innate immunity of the lung

scientific article published on 11 December 2012

Mechanisms mediating Porphyromonas gingivalis gingipain RgpA-induced oral mucosa inflammation in vivo

scientific article

Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln

scientific article

Coordinate expression of the Porphyromonas gingivalis lysine-specific gingipain proteinase, Kgp, arginine-specific gingipain proteinase, RgpA, and the heme/hemoglobin receptor, HmuR.

scientific article published in November 2004

A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus

scientific article

Detection of Porphyromonas gingivalis in gingival exudate by a dipeptide-enhanced trypsin-like activity

scientific article published on January 1994

Cleavage of IgG1 in gingival crevicular fluid is associated with the presence of Porphyromonas gingivalis

scientific article published on November 2012

Comparative properties of three functionally different but structurally related serpin variants from horse plasma

scientific article published on March 1991

Friendly fire against neutrophils: proteolytic enzymes confuse the recognition of apoptotic cells by macrophages

scientific article published on 22 September 2007

Inhibition of GSK3 abolishes bacterial-induced periodontal bone loss in mice.

scientific article

Host andPorphyromonas gingivalis proteinases in periodontitis: A biochemical model of infection and tissue destruction

article

Genome Sequence of Porphyromonas gingivalis Strain HG66 (DSM 28984).

scientific article

Bacterial proteases in disease - role in intracellular survival, evasion of coagulation/ fibrinolysis innate defenses, toxicoses and viral infections

scientific article published on January 2013

Transposition of the endogenous insertion sequence element IS1126 modulates gingipain expression in Porphyromonas gingivalis

scientific article

Gingipain aminopeptidase activities in Porphyromonas gingivalis

scientific article published on December 1, 2012

Characterization of the specificity of arginine-specific gingipains from Porphyromonas gingivalis reveals active site differences between different forms of the enzymes

scientific article published in October 2003

Inactivation of α1-Proteinase Inhibitor as a Broad Screen for Detecting Proteolytic Activities in Unknown Samples

scientific article published on July 1, 1998

Functional Analysis of Porphyromonas gingivalis W83 CRISPR-Cas Systems.

scientific article published on 26 May 2015

Dentipain, a Streptococcus pyogenes IdeS protease homolog, is a novel virulence factor of Treponema denticola

scientific article

Neutrophil proteinases. Caution signs in designing inhibitors against enzymes with possible multiple functions

scientific article published on January 1991

Regulation of alpha 1-antichymotrypsin synthesis in cells of epithelial origin

scientific article published on 01 February 1995

Comparative properties of human alpha-1-proteinase inhibitor glycosylation variants

scientific article published on October 1990

The Janus face of α-toxin: a potent mediator of cytoprotection in staphylococci-infected macrophages

scientific article

Inhibition of Porphyromonas gingivalis proteinases (gingipains) by chlorhexidine: synergistic effect of Zn(II)

scientific article published on 01 August 2006

The role of bacterial and host proteinases in periodontal disease

scientific article

A comparison of staphostatin B with standard mechanism serine protease inhibitors

scientific article published on 11 January 2005

Peptidylarginine deiminase from Porphyromonas gingivalis contributes to infection of gingival fibroblasts and induction of prostaglandin E2 -signaling pathway.

scientific article

The role of Mcl-1 in S. aureus-induced cytoprotection of infected macrophages

scientific article published on 28 January 2013

Genetic characterization of staphopain genes in Staphylococcus aureus

scientific article published in November 2004

Inhibition of Staphylococcus aureus cysteine proteases by human serpin potentially limits staphylococcal virulence

scientific article published on May 2011

In vivo sortase A and clumping factor A mRNA expression during Staphylococcus aureus infection

scientific article published on 21 August 2007

Modification of cystatin C activity by bacterial proteinases and neutrophil elastase in periodontitis

scientific article published on December 1, 1997

The nucleocapsid protein of human coronavirus NL63

scientific article

List of works by Jan Potempa

Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-α and interleukin-1β but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gi

Gingival fibromatosis: clinical, molecular and therapeutic issues

Epigenetic regulation in bacterial infections: targeting histone deacetylases

The Clostridium ramosum IgA proteinase represents a novel type of metalloendopeptidase

Development of loop-mediated isothermal amplification assay for detection of human coronavirus-NL63

Prostaphopain B structure: a comparison of proregion-mediated and staphostatin-mediated protease inhibition

Proteolytic inactivation of alpha-1-anti-chymotrypsin. Sites of cleavage and generation of chemotactic activity

A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement System

Concentration of antibodies against Porphyromonas gingivalis is increased before the onset of symptoms of rheumatoid arthritis

Mirolase, a novel subtilisin-like serine protease from the periodontopathogen Tannerella forsythia

Prevalence of genes encoding extracellular proteases in Staphylococcus aureus - important targets triggering immune response in vivo.

Noncanonical activation of β-catenin by Porphyromonas gingivalis

Citrullination as a plausible link to periodontitis, rheumatoid arthritis, atherosclerosis and Alzheimer’s disease.

Inhibition of distant caspase homologues by natural caspase inhibitors

Ribonucleotide reductase class III, an essential enzyme for the anaerobic growth of Staphylococcus aureus, is a virulence determinant in septic arthritis

Thrombin-activable fibrinolysis inhibitor (TAFI) zymogen is an active carboxypeptidase

Serpin alpha 1proteinase inhibitor probed by intrinsic tryptophan fluorescence spectroscopy

Staphylococcus aureus proteases degrade lung surfactant protein A potentially impairing innate immunity of the lung

Mechanisms mediating Porphyromonas gingivalis gingipain RgpA-induced oral mucosa inflammation in vivo

Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln

Coordinate expression of the Porphyromonas gingivalis lysine-specific gingipain proteinase, Kgp, arginine-specific gingipain proteinase, RgpA, and the heme/hemoglobin receptor, HmuR.

A novel class of cysteine protease inhibitors: solution structure of staphostatin A from Staphylococcus aureus

Detection of Porphyromonas gingivalis in gingival exudate by a dipeptide-enhanced trypsin-like activity

Cleavage of IgG1 in gingival crevicular fluid is associated with the presence of Porphyromonas gingivalis

Comparative properties of three functionally different but structurally related serpin variants from horse plasma

Friendly fire against neutrophils: proteolytic enzymes confuse the recognition of apoptotic cells by macrophages

Inhibition of GSK3 abolishes bacterial-induced periodontal bone loss in mice.

Host andPorphyromonas gingivalis proteinases in periodontitis: A biochemical model of infection and tissue destruction

Genome Sequence of Porphyromonas gingivalis Strain HG66 (DSM 28984).

Bacterial proteases in disease - role in intracellular survival, evasion of coagulation/ fibrinolysis innate defenses, toxicoses and viral infections

Transposition of the endogenous insertion sequence element IS1126 modulates gingipain expression in Porphyromonas gingivalis

Gingipain aminopeptidase activities in Porphyromonas gingivalis

Characterization of the specificity of arginine-specific gingipains from Porphyromonas gingivalis reveals active site differences between different forms of the enzymes

Inactivation of α1-Proteinase Inhibitor as a Broad Screen for Detecting Proteolytic Activities in Unknown Samples

Functional Analysis of Porphyromonas gingivalis W83 CRISPR-Cas Systems.

Dentipain, a Streptococcus pyogenes IdeS protease homolog, is a novel virulence factor of Treponema denticola

Neutrophil proteinases. Caution signs in designing inhibitors against enzymes with possible multiple functions

Regulation of alpha 1-antichymotrypsin synthesis in cells of epithelial origin

Comparative properties of human alpha-1-proteinase inhibitor glycosylation variants

The Janus face of α-toxin: a potent mediator of cytoprotection in staphylococci-infected macrophages

Inhibition of Porphyromonas gingivalis proteinases (gingipains) by chlorhexidine: synergistic effect of Zn(II)

The role of bacterial and host proteinases in periodontal disease

A comparison of staphostatin B with standard mechanism serine protease inhibitors

Peptidylarginine deiminase from Porphyromonas gingivalis contributes to infection of gingival fibroblasts and induction of prostaglandin E2 -signaling pathway.

The role of Mcl-1 in S. aureus-induced cytoprotection of infected macrophages

Genetic characterization of staphopain genes in Staphylococcus aureus

Inhibition of Staphylococcus aureus cysteine proteases by human serpin potentially limits staphylococcal virulence

In vivo sortase A and clumping factor A mRNA expression during Staphylococcus aureus infection

Modification of cystatin C activity by bacterial proteinases and neutrophil elastase in periodontitis

The nucleocapsid protein of human coronavirus NL63