Search filters

List of works by Jennifer A. Brody

A Comprehensive Evaluation of the Genetic Architecture of Sudden Cardiac Arrest

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

scientific article

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology

scientific article published on 14 January 2019

A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium

scientific article published on 30 December 2016

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A large-scale exome array analysis of venous thromboembolism

scientific article published on 19 January 2019

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

scientific article

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

scientific article published on 10 April 2019

ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article

Absence of anti-HMG-CoA reductase autoantibodies in severe self-limited statin-related myopathy

scientific article

Analysis commons, a team approach to discovery in a big-data environment for genetic epidemiology

scientific article published in October 2017

Analysis of loss-of-function variants and 20 risk factor phenotypes in 8,554 individuals identifies loci influencing chronic disease

scientific article published on 27 April 2015

Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study.

scientific article published on 20 May 2017

Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals

scientific article published on 01 August 2019

Association of exome sequences with plasma C-reactive protein levels in >9000 participants

scientific article

Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article (publication date: June 2014)

Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks

scientific article

Association of the IGF1 gene with fasting insulin levels

scientific article published on 10 February 2016

Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium

scientific article

Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease

scientific article published on 19 August 2019

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

scientific article

Circulating n-3 fatty acids and trans-fatty acids, PLA2G2A gene variation and sudden cardiac arrest

scientific article published on March 2016

Common Coding Variants in Are Associated With the Nav1.8 Late Current and Cardiac Conduction

scientific article published on 01 May 2018

Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

Common variation in fatty acid metabolic genes and risk of incident sudden cardiac arrest

scientific article published on 10 January 2014

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study

scientific article

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking

scientific article published on 19 September 2019

Correction to: Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study

scientific article published on 01 May 2018

DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

scientific article published on 30 November 2017

DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies

article published in 2018

DNA methylation age is associated with an altered hemostatic profile in a multi-ethnic meta-analysis

article

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

scientific article published on 12 December 2016

Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia

scientific article

Discovery of novel heart rate-associated loci using the Exome Chip

scientific article

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium

scientific article

Effect of Sex and Underlying Disease on the Genetic Association of QT Interval and Sudden Cardiac Death

scientific article published on 21 November 2019

Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals

scientific article published on 01 June 2019

Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies

scientific article published on 10 January 2019

Epigenetic Signatures of Cigarette Smoking

scientific article

Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations

scientific article published on 01 August 2019

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

scientific article published in July 2017

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

article by Jason Flannick et al published 22 May 2019 in Nature

Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

FastSKAT: Sequence kernel association tests for very large sets of markers

scientific article published on 22 June 2018

Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

scientific article

GATM locus does not replicate in rhabdomyolysis study.

scientific article published in September 2014

Genetic Determinants of Electrocardiographic P-wave Duration and Relation to Atrial Fibrillation

scientific article published on 21 August 2020

Genetic association testing using the GENESIS R/Bioconductor package

scientific article published on 01 December 2019

Genetic diversity is a predictor of mortality in humans

scientific article

Genetic insights into biological mechanisms governing human ovarian ageing

scientific article

Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

scientific article published on 13 November 2020

Genome of The Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

scientific article

Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index

scientific article published on 10 March 2015

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

scientific article published on 19 December 2016

Genome-wide association and functional studies identify 46 novel loci for alcohol consumption and suggest common genetic mechanisms with neuropsychiatric disorders

Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits

scientific article published on 24 January 2019

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association study and meta-analysis identify loci associated with ventricular and supraventricular ectopy.

scientific article published on 4 April 2018

Genome-wide meta-analysis of SNP and antihypertensive medication interactions on left ventricular traits in African Americans

scientific article published on 13 August 2019

Genomewide Association Study of Statin-Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink

scientific article published on 31 July 2019

Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism

scientific article published on 01 November 2019

Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program

scientific article published on 26 September 2019

Integrative pathway genomics of lung function and airflow obstruction

scientific article

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

scientific article

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

scientific article published in December 2015

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

scientific article published on 10 April 2017

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

scientific article published on 10 May 2019

Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

scientific article published on 12 September 2016

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

scientific article

Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism

scientific article

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs

scientific article published on 28 September 2020

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

Novel Genetic Loci Associated With Retinal Microvascular Diameter

scientific article published on 13 November 2015

Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese

scientific article published on 30 January 2014

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium

scientific article

Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

scientific article published on 26 June 2019

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

scientific article

Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk

scientific article published on 11 December 2015

Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease

scientific article

Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

scientific article published on 5 December 2016

Sequence kernel association test for survival traits.

scientific article

Sequence variation in TMEM18 in association with body mass index: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article

Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

scientific article published on 6 March 2019

Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

scientific article

Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

scientific article

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study

scientific article (publication date: March 2014)

Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study

scientific article published on 11 September 2016

The Polygenic and Monogenic Basis of Blood Traits and Diseases

scientific article published on 01 September 2020

The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels

scientific article

The impact of the housing status on clinical outcomes and health care utilization among individuals living with HIV

scientific article published on 25 November 2019

The transcriptional landscape of age in human peripheral blood

scientific article

Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations

scientific article published on 01 September 2020

WGSA: an annotation pipeline for human genome sequencing studies.

scientific article published on 22 September 2015

Whole Blood DNA Methylation Signatures of Diet Are Associated with Cardiovascular Disease Risk Factors and All-cause Mortality

scientific article published on 11 June 2020

Whole Exome Sequencing in Atrial Fibrillation

scientific article

Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation

scientific article published on 16 March 2017

Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium

scientific article published on 05 January 2021

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

scientific article

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

article

Paulina is supported by:

About Paulina

Help