List of works by Dawn Waterworth

A Systematic Review of Biomarkers and Risk of Incident Type 2 Diabetes: An Overview of Epidemiological, Prediction and Aetiological Research Literature

scientific article

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study of neuroticism in a population-based sample

scientific article (publication date: 9 July 2010)

A genome-wide association study reveals variants in ARL15 that influence adiponectin levels

scientific article

A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

scientific article

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

scientific article published on June 2016

A low-frequency variant in MAPK14 provides mechanistic evidence of a link with myeloperoxidase: a prognostic cardiovascular risk marker

scientific article

A phenome-wide association study of a lipoprotein-associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults

scientific article published on 14 June 2016

An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank

scientific article published on 12 April 2019

Association of ABCB1 genetic variants with renal function in Africans and in Caucasians

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Body Mass Index and Risk of Nonalcoholic Fatty Liver Disease: Two Electronic Health Record Prospective Studies

scientific article published on 16 December 2015

CUBN is a gene locus for albuminuria

scientific article

Cardiovascular and Lifestyle Risk Factors and Cognitive Function in Patients With Stable Coronary Heart Disease

Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males

scientific article (publication date: 5 April 2011)

Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals

scientific article

Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

scientific article

Common variants near MC4R are associated with fat mass, weight and risk of obesity

scientific article

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

scientific article published on 27 July 2009

Corrigendum: Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

scholarly article published in Nature Genetics

Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation

scientific article published on 8 March 2012

Definitions of Metabolic Health and Risk of Future Type 2 Diabetes in BMI Categories: A Systematic Review and Network Meta-analysis

scientific article

Disentangling the genetics of lean mass

article

Erratum to: The epigenetic signature of systemic insulin resistance in obese women.

scientific article published in December 2016

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

FGF21 signalling pathway and metabolic traits - genetic association analysis

scientific article

Factors influencing longitudinal changes of circulating liver enzyme concentrations in subjects randomized to placebo in four clinical trials

scientific article published on 29 November 2018

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease

scientific article

Genetic and phenotypic architecture of metabolic syndrome-associated components in dyslipidemic and normolipidemic subjects: The GEMS Study

article

Genetic architecture of ambulatory blood pressure in the general population: insights from cardiovascular gene-centric array

scientific article

Genetic loci influencing kidney function and chronic kidney disease

scientific article

Genetic polymorphisms of the main transcription factors for adiponectin gene promoter in regulation of adiponectin levels: association analysis in three European cohorts

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants influencing circulating lipid levels and risk of coronary artery disease

scientific article published on 23 September 2010

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation in LIN28B is associated with the timing of puberty

scientific article

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

scientific article published on 09 January 2020

Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption

scientific journal article

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

scientific article

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009

Genome-wide association studies using an adaptive two-stage analysis for a case-control design

scientific article

Genome-wide association study identifies 48 common genetic variants associated with handedness

scientific article published on 28 September 2020

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

scientific article published on 16 October 2011

Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy

scientific article published on 15 August 2010

Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links

scientific article (publication date: February 2014)

Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study

scientific article

Genome-wide meta-analysis for serum calcium identifies significantly associated SNPs near the calcium-sensing receptor (CASR) gene

scientific article

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Identification and validation of copy number variants using SNP genotyping arrays from a large clinical cohort

scientific article

Integrated Functional Genomic Analysis Enables Annotation of Kidney Genome-Wide Association Study Loci.

scientific article published on 13 February 2019

Interaction between insulin (VNTR) and hepatic lipase (LIPC-514C>T) variants on the response to an oral glucose tolerance test in the EARSII group of young healthy men.

scientific article published in June 2005

Interleukin-18 as a drug repositioning opportunity for inflammatory bowel disease: A Mendelian randomization study

scientific article published on 28 June 2019

LDL-cholesterol concentrations: a genome-wide association study

scientific article

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

scientific article

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

scientific article

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

scientific article published on 12 July 2017

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Lipoprotein-Associated Phospholipase A2 Loss-of-Function Variant and Risk of Vascular Diseases in 90,000 Chinese Adults

scientific article published on January 2016

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease

scientific article published in PLoS ONE

Male-pattern baldness susceptibility locus at 20p11.

scientific article

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

scientific article

Meta-analysis of 26,638 Individuals Identifies Two Genetic Loci Associated with Left Ventricular Ejection Fraction

scientific article published on 30 June 2020

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations

scientific article published in June 2009

Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design?

scientific article published on 23 October 2009

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

scientific article published on 30 October 2020

Methods for testing association between uncertain genotypes and quantitative traits

scientific article published on 11 June 2010

Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia

scientific article published in August 2005

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

No interaction between alcohol consumption and HDL-related genes on HDL cholesterol levels

scientific article

Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults

scientific article published on 08 October 2019

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Novel method to estimate the phenotypic variation explained by genome-wide association studies reveals large fraction of the missing heritability

scientific article

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation.

scientific article published on 5 July 2011

Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib

scientific article published on 28 July 2017

Pharmacological effects of lipid-lowering drugs recapitulate with a larger amplitude the phenotypic effects of common variants within their target genes

scientific article

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

scientific article published on 07 September 2020

Phenome-wide association study using research participants' self-reported data provides insight into the Th17 and IL-17 pathway

scientific article published in November 2017

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

scientific article

Polymorphisms in CYP-7A1, not APOE, influence the change in plasma lipids in response to population dietary change in an 8 year follow-up; results from the Czech MONICA study

scientific article

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

scientific article

Prospective study of insulin-like growth factor-I, insulin-like growth factor-binding protein 3, genetic variants in the IGF1 and IGFBP3 genes and risk of coronary artery disease.

scientific article

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

scientific article

Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease

article

Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project).

scientific article published in January 2005

Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts

scientific article published on 20 May 2019

Serum insulin and inflammatory markers in overweight individuals with and without dyslipidemia.

scientific article published on 27 March 2007

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article

Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases

scientific article

The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome

scientific article

The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research

scientific article published on 28 August 2008

The PsyCoLaus study: methodology and characteristics of the sample of a population-based survey on psychiatric disorders and their association with genetic and cardiovascular risk factors

scientific article

The benefits of using genetic information to design prevention trials

scientific article published on 28 March 2013

The epigenetic signature of systemic insulin resistance in obese women

scientific article

The genetics of drug efficacy: opportunities and challenges

scientific article published on 14 March 2016

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies

scientific article

Urotensin-II system in genetic control of blood pressure and renal function

scientific article

Variants in MTNR1B influence fasting glucose levels

scientific article

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