List of works - Giulio Superti-Furga

Proteome survey reveals modularity of the yeast cell machinery

scientific article

Functional organization of the yeast proteome by systematic analysis of protein complexes

scientific article

Somatic mutations of calreticulin in myeloproliferative neoplasms

scientific article

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

scientific article

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

scientific article

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data

scientific article

Peroxisomes are signaling platforms for antiviral innate immunity

scientific article

Structural basis for the autoinhibition of c-Abl tyrosine kinase

scientific article (publication date: 21 March 2003)

ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins

scientific article

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

scientific article published on 24 August 2007

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

scientific article

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling.

scientific article published in October 1999

The promise and peril of chemical probes

scientific article

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

scientific article published on 5 October 2011

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

scientific article

Regulation of the c-Abl and Bcr-Abl tyrosine kinases

scientific article published on January 2004

Target profiling of small molecules by chemical proteomics

scientific article

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

scientific article

Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

scientific article published on February 1997

Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter

article

Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation

scientific article

A myristoyl/phosphotyrosine switch regulates c-Abl

scientific article published on March 2003

An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells

scientific article

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

scientific article

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

scientific article

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

scholarly article

Viral immune modulators perturb the human molecular network by common and unique strategies

scientific article

Structure-based assembly of protein complexes in yeast

scientific article

NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase

scientific article published on 11 February 2009

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

scientific article

RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane

scientific article published on December 2004

A Call for Systematic Research on Solute Carriers

scientific article (publication date: 30 July 2015)

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

scientific article

An intramolecular SH3-domain interaction regulates c-Abl activity

scientific article

Autoinhibition of c-Abl

scientific article published on January 2002

c-Src-mediated phosphorylation of hnRNP K drives translational activation of specifically silenced mRNAs

scientific article

Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway

scientific article published on September 2000

The fission yeast pmk1+ gene encodes a novel mitogen-activated protein kinase homolog which regulates cell integrity and functions coordinately with the protein kinase C pathway

scientific article published on December 1996

Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells

scientific article

The minimum information required for reporting a molecular interaction experiment (MIMIx).

scientific article published on August 2007

The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions

scientific article

Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins

scientific article

Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation

scientific article

Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase

scientific article

Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib

scientific article

Charting the molecular network of the drug target Bcr-Abl

scientific article

Structure-function relationships in Src family and related protein tyrosine kinases

scientific article published on 01 April 1995

CD14 is a coreceptor of Toll-like receptors 7 and 9.

scientific article

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

scientific article

BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia

scientific article published on 29 January 2012

List of works by Giulio Superti-Furga

Proteome survey reveals modularity of the yeast cell machinery

Functional organization of the yeast proteome by systematic analysis of protein complexes

Somatic mutations of calreticulin in myeloproliferative neoplasms

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data

Peroxisomes are signaling platforms for antiviral innate immunity

Structural basis for the autoinhibition of c-Abl tyrosine kinase

ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling.

The promise and peril of chemical probes

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

Regulation of the c-Abl and Bcr-Abl tyrosine kinases

Target profiling of small molecules by chemical proteomics

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter

Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation

A myristoyl/phosphotyrosine switch regulates c-Abl

An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

Viral immune modulators perturb the human molecular network by common and unique strategies

Structure-based assembly of protein complexes in yeast

NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane

A Call for Systematic Research on Solute Carriers

The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response

An intramolecular SH3-domain interaction regulates c-Abl activity

Autoinhibition of c-Abl

c-Src-mediated phosphorylation of hnRNP K drives translational activation of specifically silenced mRNAs

Myotubularin, a phosphatase deficient in myotubular myopathy, acts on phosphatidylinositol 3-kinase and phosphatidylinositol 3-phosphate pathway

The fission yeast pmk1+ gene encodes a novel mitogen-activated protein kinase homolog which regulates cell integrity and functions coordinately with the protein kinase C pathway

Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells

The minimum information required for reporting a molecular interaction experiment (MIMIx).

The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions

Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins

Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation

Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase

Target spectrum of the BCR-ABL inhibitors imatinib, nilotinib and dasatinib

Charting the molecular network of the drug target Bcr-Abl

Structure-function relationships in Src family and related protein tyrosine kinases

CD14 is a coreceptor of Toll-like receptors 7 and 9.

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia