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List of works by Hugh S Markus

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Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article
Genome-wide association analysis identifies 13 new risk loci for schizophrenia

scientific article published in October 2013
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

scientific article
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies

scientific article published on 5 October 2012
Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016
Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations

scientific article
Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke

scientific article
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

scientific article published on 11 September 2011
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018
Vertebral artery stenting to prevent recurrent stroke in symptomatic vertebral artery stenosis: the VIST RCT

scientific article published in August 2019
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)
Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

scientific article published in August 2012
Ischemic stroke is associated with the ABO locus: the EuroCLOT study

scientific article published on January 2013
Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection.

scientific article
Epidemiology, pathophysiology, diagnosis, and management of intracranial artery dissection

scientific article
Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.

scientific article
An Examination of Polygenic Score Risk Prediction in Individuals With First-Episode Psychosis

scientific article
Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration

scientific article
Early dual versus mono antiplatelet therapy for acute non-cardioembolic ischemic stroke or transient ischemic attack: an updated systematic review and meta-analysis

scientific article
Modifiable pathways in Alzheimer's disease: Mendelian randomisation analysis

scientific article published on 6 December 2017
A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

scientific article
Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies

scientific article
Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes

scientific article
A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation

scientific article published on 17 July 2013
The effectiveness of dual antiplatelet treatment in acute ischemic stroke patients with intracranial arterial stenosis: a subgroup analysis of CLAIR study.

scientific article published on 7 August 2012
Germline selection shapes human mitochondrial DNA diversity

scientific article published on 23 May 2019
17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status

scientific article
Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data

article
Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes: Mendelian randomization study

scientific article
Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype

scientific article
Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants

scientific article published in the British Medical Journal
Genome-wide genotyping demonstrates a polygenic risk score associated with white matter hyperintensity volume in CADASIL.

scientific article
Role of Blood Lipids in the Development of Ischemic Stroke and its Subtypes: A Mendelian Randomization Study

scientific article
Genetic variation at 16q24.2 is associated with small vessel stroke

scientific article
Length of carotid stenosis predicts peri-procedural stroke or death and restenosis in patients randomized to endovascular treatment or endarterectomy

scientific article
Differences in Common Genetic Predisposition to Ischemic Stroke by Age and Sex

scientific article
Common coding variant in SERPINA1 increases the risk for large artery stroke

scientific article
Genetic variation in the lymphotoxin-alpha pathway and the risk of ischemic stroke in European populations

scientific article published on 29 January 2009
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications
Sodium Valproate, a Histone Deacetylase Inhibitor, Is Associated With Reduced Stroke Risk After Previous Ischemic Stroke or Transient Ischemic Attack

scientific article published on 15 December 2017
APOE ɛ2 is associated with white matter hyperintensity volume in CADASIL

scientific article published on 29 April 2015
Pathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network

scientific article
Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia

scientific article
Genetics of stroke in a UK African ancestry case-control study: South London Ethnicity and Stroke Study

scientific article published on 15 March 2017
Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms

scientific article published on 3 May 2017
Genetic and environmental risk factors for rheumatoid arthritis in a UK African ancestry population: the GENRA case-control study

scientific article published on 12 April 2017
Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke

scientific article published in October 2017
Polygenic overlap between kidney function and large artery atherosclerotic stroke

scientific article

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