List of works - Allan Levey

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

scientific article

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Vitamin E and donepezil for the treatment of mild cognitive impairment

scientific article

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

scientific article published on July 1, 1995

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

scientific article

5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging

scientific article published on 30 October 2011

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

article

Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases

scientific article

Dopamine Axon Varicosities in the Prelimbic Division of the Rat Prefrontal Cortex Exhibit Sparse Immunoreactivity for the Dopamine Transporter

scientific article published on April 1, 1998

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

scientific article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases

scientific article

Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice

scientific article published on November 25, 1997

Loss of apolipoprotein E receptor LR11 in Alzheimer disease

scientific article

A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction

scientific article published on 10 November 2005

Implanted neural electrodes cause chronic, local inflammation that is correlated with local neurodegeneration.

scientific article published on 21 August 2009

Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function

scientific article

Activation of the genetically defined m1 muscarinic receptor potentiates N -methyl- d -aspartate (NMDA) receptor currents in hippocampal pyramidal cells

scientific article published on September 15, 1998

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice.

scientific article published in March 2002

Oxidative modifications and aggregation of Cu,Zn-superoxide dismutase associated with Alzheimer and Parkinson diseases

scientific article published on 19 January 2005

Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats.

scientific article published on October 2008

Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection

scientific article published on 25 June 2004

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.

scientific article

Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

scientific article

Dopaminergic Neurons Intrinsic to the Primate Striatum

scientific article published on September 1, 1997

Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease

scientific article

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease

scientific article published on 10 September 2013

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

scientific journal article

A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning

scientific article

Differential expression of D1 and D2 dopamine and m4 muscarinic acetylcholine receptor proteins in identified striatonigral neurons

scientific article published on December 1, 1997

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

scientific article

A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease

scientific article published on 14 December 2016

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease

scientific article published on September 2006

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

scientific article published in August 2012

Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking

scientific article (publication date: 2 August 2002)

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease

scientific article

The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation

scientific article

Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra

scientific article published on November 17, 1997

Proteomic identification of novel proteins associated with Lewy bodies

scientific article published on May 2008

Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease

scientific article

Rab11a and myosin Vb regulate recycling of the M4 muscarinic acetylcholine receptor.

scientific article published in November 2002

Mild cognitive impairment: an opportunity to identify patients at high risk for progression to Alzheimer's disease

scientific article published on July 2006

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

scientific article published on 19 January 2014

TREM2 is associated with increased risk for Alzheimer's disease in African Americans

scientific article published on 10 April 2015

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

scientific article published in June 2019

Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease

scientific journal article

List of works by Allan Levey

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Vitamin E and donepezil for the treatment of mild cognitive impairment

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases

Dopamine Axon Varicosities in the Prelimbic Division of the Rat Prefrontal Cortex Exhibit Sparse Immunoreactivity for the Dopamine Transporter

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

Analysis of shared heritability in common disorders of the brain

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases

Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice

Loss of apolipoprotein E receptor LR11 in Alzheimer disease

A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction

Implanted neural electrodes cause chronic, local inflammation that is correlated with local neurodegeneration.

Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function

Activation of the genetically defined m1 muscarinic receptor potentiates N -methyl- d -aspartate (NMDA) receptor currents in hippocampal pyramidal cells

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice.

Oxidative modifications and aggregation of Cu,Zn-superoxide dismutase associated with Alzheimer and Parkinson diseases

Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats.

Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection

Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.

Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease

Dopaminergic Neurons Intrinsic to the Primate Striatum

Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease

U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning

Differential expression of D1 and D2 dopamine and m4 muscarinic acetylcholine receptor proteins in identified striatonigral neurons

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism

Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease

The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation

Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra

Proteomic identification of novel proteins associated with Lewy bodies

Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease

Rab11a and myosin Vb regulate recycling of the M4 muscarinic acetylcholine receptor.

Mild cognitive impairment: an opportunity to identify patients at high risk for progression to Alzheimer's disease

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

TREM2 is associated with increased risk for Alzheimer's disease in African Americans

Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report

Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease