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List of works by Mark O Goodarzi

A Comprehensive Analysis of Common and Rare Variants to Identify Adiposity Loci in Hispanic Americans: The IRAS Family Study (IRASFS).

scientific article published on 24 November 2015

A Long Non-coding RNA, LOC157273, Is an Effector Transcript at the Chromosome 8p23.1-PPP1R3B Metabolic Traits and Type 2 Diabetes Risk Locus

scientific article published on 10 July 2020

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

scientific article published on 24 March 2017

A Multinomial Ordinal Probit Model with Singular Value Decomposition Method for a Multinomial Trait ⬇️

scientific article published on March 31, 2012

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

A genome-wide association scan for acute insulin response to glucose in Hispanic-Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS FS).

scientific article

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3

scientific article

A genome-wide association study of early menopause and the combined impact of identified variants

scientific article published on 9 January 2013

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

scientific article published on June 2016

A novel method for testing association of multiple genetic markers with a multinomial trait.

scientific article

A pilot randomized, single-blind, placebo-controlled trial of traditional acupuncture for vasomotor symptoms and mechanistic pathways of menopause

scientific article published on January 2012

A prevalent caveolin-1 gene variant is associated with the metabolic syndrome in Caucasians and Hispanics

scientific article

Adipocytes from women with polycystic ovary syndrome demonstrate altered phosphorylation and activity of glycogen synthase kinase 3.

scientific article published on 07 January 2008

Adiponectin, Insulin Sensitivity and Diabetic Retinopathy in Latinos With Type 2 Diabetes

scientific article

Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans

scientific article published on 01 March 2019

Alterations of a Cellular Cholesterol Metabolism Network Are a Molecular Feature of Obesity-Related Type 2 Diabetes and Cardiovascular Disease

scientific article

Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study

scientific article published on 26 March 2009

Antidiabetic Medications and Mortality Risk in Individuals With Pancreatic Cancer-Related Diabetes and Postpancreatitis Diabetes: A Nationwide Cohort Study

scientific article published on 21 June 2019

Association between Site-specific Bone Mineral Density and Glucose Homeostasis and Anthropometric Traits in Healthy Men and Women

scientific article published on 25 March 2018

Association of CYP3A7*1C and serum dehydroepiandrosterone sulfate levels in women with polycystic ovary syndrome

scientific article published on 29 April 2008

Association of TCF7L2 gene polymorphisms with reduced acute insulin response in Hispanic Americans

scientific article

Association of androgen receptor CAG repeat polymorphism and polycystic ovary syndrome

scientific article published on 26 February 2008

Association of fasting insulin and C peptide with diabetic retinopathy in Latinos with type 2 diabetes

scientific article

Association of the diabetes gene calpain-10 with subclinical atherosclerosis: the Mexican-American Coronary Artery Disease Study

scientific article published in April 2005

Association study of AMP-activated protein kinase subunit genes in polycystic ovary syndrome

scientific article published on 02 July 2009

Association study of CYP17 and HSD11B1 in polycystic ovary syndrome utilizing comprehensive gene coverage

scientific article

Association study of androgen signaling pathway genes in polycystic ovary syndrome

scientific article published on 19 October 2015

Association study of four key folliculogenesis genes in polycystic ovary syndrome

scientific article

Associations between adherence to the dietary approaches to stop hypertension (DASH) diet and six glucose homeostasis traits in the Microbiome and Insulin Longitudinal Evaluation Study (MILES)

scientific article published in 2022

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Associations of SNPs in ADIPOQ and subclinical cardiovascular disease in the multi-ethnic study of atherosclerosis (MESA).

scientific article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Bidirectional Mendelian randomization to explore the causal relationships between body mass index and polycystic ovary syndrome

scientific article published on 01 January 2019

Blood glucose: a strong risk factor for mortality in nondiabetic patients with cardiovascular disease

scientific article published in August 2005

Body Adiposity Index versus Body Mass Index and Other Anthropometric Traits as Correlates of Cardiometabolic Risk Factors ⬇️

scientific article published on June 11, 2013

CRTC3 links catecholamine signalling to energy balance

scientific journal article

Changes in FTO and IRX3 gene expression in obese and overweight male adolescents undergoing an intensive lifestyle intervention and the role of FTO genotype in this interaction

article

Classification of Type 2 Diabetes Genetic Variants and a Novel Genetic Risk Score Association With Insulin Clearance

scientific article published on 01 April 2020

Comment on Moore et al. Increased risk of cognitive impairment in patients with diabetes is associated with metformin. Diabetes care 2013;36:2981-2987.

scientific article published on June 2014

Common Genetic Determinants of Vitamin D Insufficiency: A Genome-Wide Association Study

Common genetic determinants of vitamin D insufficiency: a genome-wide association study

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Comparison of Genome-Wide and Gene-Specific DNA Methylation Profiling in First-Trimester Chorionic Villi From Pregnancies Conceived With Infertility Treatments

scientific article published on January 2016

Components of metabolic syndrome and 5‐year change in insulin clearance – the Insulin Resistance Atherosclerosis Study ⬇️

scientific article published on January 21, 2013

Comprehensive assessment of expression of insulin signaling pathway components in subcutaneous adipose tissue of women with and without polycystic ovary syndrome

scientific article published in September 2015

Correction: Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

scientific article published on 05 December 2019

Correlation of adrenocorticotropin steroid levels between women with polycystic ovary syndrome and their sisters

scientific article published on 01 April 2007

Corrigendum: Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations

scientific article published on 12 February 2016

DHEA, DHEAS and PCOS.

scientific article published on 05 July 2014

Detection of genetic loci associated with plasma fetuin-A: a meta-analysis of genome-wide association studies from the CHARGE Consortium

scientific article published on 3 April 2017

Determination and use of haplotypes: ethnic comparison and association of the lipoprotein lipase gene and coronary artery disease in Mexican-Americans

scientific article published in July 2003

Diabetes Mellitus and Obesity as Risk Factors for Pancreatic Cancer

scientific article published on 11 September 2017

Diagnosis, epidemiology, and genetics of the polycystic ovary syndrome

scientific article published on June 2006

Differences in First-Trimester Maternal Metabolomic Profiles in Pregnancies Conceived From Fertility Treatments

scientific article published on 01 April 2019

Differential gene expression during placentation in pregnancies conceived with different fertility treatments compared with spontaneous pregnancies

scientific article published on 02 January 2019

Discovery and refinement of loci associated with lipid levels

scientific article

Early embryonic androgen exposure induces transgenerational epigenetic and metabolic changes

scientific article

Epigenetic mechanism underlying the development of polycystic ovary syndrome (PCOS)-like phenotypes in prenatally androgenized rhesus monkeys

scientific article published in 2011

Epigenetics in polycystic ovary syndrome: a pilot study of global DNA methylation

scientific article

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Evaluation of a Mixed Meal Test for Diagnosis and Characterization of PancrEaTogEniC DiabeTes Secondary to Pancreatic Cancer and Chronic Pancreatitis: Rationale and Methodology for the DETECT Study From the Consortium for the Study of Chronic Pancrea

scientific article published on 01 November 2018

Exome-wide association study of plasma lipids in >300,000 individuals

scientific article published on 30 October 2017

FEM1A and FEM1B: novel candidate genes for polycystic ovary syndrome

scientific article published on 29 August 2008

FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome

scientific article

Fasting glucose GWAS candidate region analysis across ethnic groups in the Multiethnic Study of Atherosclerosis (MESA).

scientific article

Fasting insulin reflects heterogeneous physiological processes: role of insulin clearance ⬇️

scientific article published on May 31, 2011

First evidence of genetic association between AKT2 and polycystic ovary syndrome

scientific article published on 03 September 2008

Function and Hormonal Regulation of GATA3 in Human First Trimester Placentation

scientific article published on 12 October 2016

Further investigation in europeans of susceptibility variants for polycystic ovary syndrome discovered in genome-wide association studies of Chinese individuals

scientific article

Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site

scientific article

General Framework for Meta-Analysis of Haplotype Association Tests

scientific article published on 8 March 2016

Genes for enzymes regulating dehydroepiandrosterone sulfonation are associated with levels of dehydroepiandrosterone sulfate in polycystic ovary syndrome

scientific article published on 10 April 2007

Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus

scientific article published on 01 July 2019

Genetic Variants Associated With Obesity and Insulin Resistance in Hispanic Boys With Nonalcoholic Fatty Liver Disease

scientific article published on 21 February 2018

Genetic Variants Associated With Quantitative Glucose Homeostasis Traits Translate to Type 2 Diabetes in Mexican Americans: The GUARDIAN (Genetics Underlying Diabetes in Hispanics) Consortium

scientific article

Genetic determinants of polycystic ovary syndrome: progress and future directions

scientific article published on 11 May 2016

Genetic loci associated with nonobstructive coronary artery disease in Caucasian women

scientific article published on 3 November 2015

Genetic markers: progress and potential for cardiovascular disease

scientific article published in June 2004

Genetic variants in peroxisome proliferator-activated receptor gamma influence insulin resistance and testosterone levels in normal women, but not those with polycystic ovary syndrome

scientific article published on 4 December 2006

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetics of Common Endocrine Disease: The Present and the Future

scientific article published on 23 February 2016

Genetics of obesity: what genetic association studies have taught us about the biology of obesity and its complications

scientific article

Genome-Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium

scientific article published on 20 June 2019

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

scientific article published on 14 July 2016

Genome-Wide Associations Related to Hepatic Histology in Nonalcoholic Fatty Liver Disease in Hispanic Boys

scientific article published on 14 September 2017

Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations

scientific article

Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease

scientific article

Genome-wide association study in a Chinese population with diabetic retinopathy ⬇️

scientific article published on 04 April 2013

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

scientific article published on 21 June 2016

Glucose lowering to control macrovascular disease in type 2 diabetes: treating the wrong surrogate end point?

scientific article

Haplotypes in the lipoprotein lipase gene influence fasting insulin and discovery of a new risk haplotype

scientific article published on 10 October 2006

Haplotypes in the lipoprotein lipase gene influence high-density lipoprotein cholesterol response to statin therapy and progression of atherosclerosis in coronary artery bypass grafts

scientific article published on 06 June 2006

Harnessing expression data to identify novel candidate genes in polycystic ovary syndrome

scientific article (publication date: 2011)

Heritability of dehydroepiandrosterone sulfate in women with polycystic ovary syndrome and their sisters

scientific article published on 30 October 2006

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

scientific article published on 23 March 2015

Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene

scientific article published on 4 January 2016

Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome: a systematic review and meta-analysis

scientific article

Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program

scientific article published on 26 September 2019

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

Improved Performance of Dynamic Measures of Insulin Response Over Surrogate Indices to Identify Genetic Contributors of Type 2 Diabetes: The GUARDIAN Consortium

scientific article published on 03 May 2016

Increased prenatal exposure to cortisol and lifelong health consequences in women

scientific article published on 24 July 2019

Independent confirmation of association between metabolic phenotypes of polycystic ovary syndrome and variation in the type 6 17beta-hydroxysteroid dehydrogenase gene

scientific article published on 16 October 2009

Insulin Clearance Is Associated with Hepatic Lipase Activity and Lipid and Adiposity Traits in Mexican Americans

scientific article

Insulin clearance and the incidence of type 2 diabetes in Hispanics and African Americans: the IRAS Family Study

scientific article published on 5 December 2012

Insulin clearance: confirmation as a highly heritable trait, and genome-wide linkage analysis ⬇️

scientific article published on May 16, 2012

Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans

scientific article

Interactions between macro-nutrients' intake, FTO and IRX3 gene expression, and FTO genotype in obese and overweight male adolescents

scientific article published on 01 December 2019

Intrauterine environment and polycystic ovary syndrome

scientific article published on 8 April 2014

Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair

scientific article published in December 2015

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

scientific article published on 19 December 2018

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

scientific article published in November 2015

Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4

scientific journal article

Lipoprotein lipase is a gene for insulin resistance in Mexican Americans

scientific article published in January 2004

Looking for polycystic ovary syndrome genes: rational and best strategy

scientific article published on January 2008

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

scientific article

Lysine-specific demethylase 1: an epigenetic regulator of salt-sensitive hypertension

scientific article published on 26 April 2012

Meta-analysis of association of FTO genetic variation with PCOS must account for obesity

scientific article published on 16 December 2019

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes

scientific article

Meta-analysis of loci associated with age at natural menopause in African-American women ⬇️

scientific article

Metabolic and cardiovascular genes in polycystic ovary syndrome: a candidate-wide association study (CWAS).

scientific article published on 08 December 2011

Metabolites Linking the Gut Microbiome with Risk for Type 2 Diabetes

scientific article published on 09 March 2020

Metabolomics Identifies Distinctive Metabolite Signatures for Measures of Glucose Homeostasis: The Insulin Resistance Atherosclerosis Family Study (IRAS-FS).

scientific article published on 13 March 2018

Metformin revisited: re-evaluation of its properties and role in the pharmacopoeia of modern antidiabetic agents

scientific article

Metformin use in polycystic ovary syndrome: metabolic benefits and diabetes prevention

scientific article published in August 2008

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

scientific article published on 21 November 2016

Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians

scientific article

Negative association between androgen receptor gene CAG repeat polymorphism and polycystic ovary syndrome? A systematic review and meta-analysis

scientific article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

scientific article published on 13 March 2012

Nonhuman primate models of polycystic ovary syndrome ⬇️

scientific article published on January 29, 2013

Nonreplication of the type 5 17beta-hydroxysteroid dehydrogenase gene association with polycystic ovary syndrome

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

OR15-6 Epigenetic Differences in First Trimester Pregnancies Conceived with Infertility.

scientific article published on 30 April 2019

Optimization of techniques for multiple platform testing in small, precious samples such as human chorionic villus sampling

scientific article

Pathological Mechanisms in Diabetes of the Exocrine Pancreas: What's Known and What's to Know

scientific article published on 28 October 2020

Personalized medicine and pharmacogenetic biomarkers: progress in molecular oncology testing

scientific article

Pharmacometabolomic signature links simvastatin therapy and insulin resistance

scientific article

Physical Activity Associations with Bone Mineral Density and Modification by Metabolic Traits

scientific article published on 07 July 2020

Polycystic Ovary Syndrome and Risk of Type 2 Diabetes, Coronary Heart Disease, and Stroke

scientific article published on 06 November 2020

Polycystic ovary syndrome in Mexican-Americans: prevalence and association with the severity of insulin resistance

scientific article published in September 2005

Polycystic ovary syndrome: an ancient disorder?

scientific article

Polycystic ovary syndrome: etiology, pathogenesis and diagnosis

scientific article published on 25 January 2011

Population structure of Hispanics in the United States: the multi-ethnic study of atherosclerosis

scientific article

Preliminary evidence of glycogen synthase kinase 3 beta as a genetic determinant of polycystic ovary syndrome

scientific article

Publisher Correction: Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations

scientific article published on 28 April 2020

Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study

scientific article published on 5 February 2008

Rationale, Design, and Baseline Characteristics of the Microbiome and Insulin Longitudinal Evaluation Study (MILES)

scientific article published on 20 July 2020

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Relationship between circulating levels of pancreatic proteolytic enzymes and pancreatic hormones.

scientific article published on 20 September 2017

Relationship of insulin sensitivity, insulin secretion, and adiposity with insulin clearance in a multiethnic population: the insulin Resistance Atherosclerosis study

scientific article

Relationship of sex to diabetes risk in statin trials

scientific article published in July 2013

Relative impact of insulin resistance and obesity on cardiovascular risk factors in polycystic ovary syndrome

scientific article

Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts

scientific article published on 17 December 2011

Replication of association of a novel insulin receptor gene polymorphism with polycystic ovary syndrome

scientific article

Replication of calpain-10 genetic association with carotid intima-media thickness

scientific article published on 09 January 2009

Response to Liu et al

SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse

scientific article published on 10 April 2007

SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function

scientific article published on 5 December 2016

Sex differences in the late first trimester human placenta transcriptome

scientific article published on 15 January 2018

Small glutamine-rich tetratricopeptide repeat-containing protein alpha (SGTA), a candidate gene for polycystic ovary syndrome

scientific article published on 10 March 2008

Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study

scientific article published on 05 December 2019

Steroidogenic regulatory factor FOS is underexpressed in polycystic ovary syndrome (PCOS) adipose tissue and genetically associated with PCOS susceptibility

scientific article

Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance ⬇️

scientific article published on March 14, 2013

Systems Genetics Reveals the Functional Context of PCOS Loci and Identifies Genetic and Molecular Mechanisms of Disease Heterogeneity

scientific article published on 25 August 2015

Testing the gene or testing a variant? The case of TCF7L2

scientific article published on 01 October 2007

The 3' untranslated region of the lipoprotein lipase gene: haplotype structure and association with post-heparin plasma lipase activity

scientific article

The Association of Estrogen Receptor-β Gene Variation With Salt-Sensitive Blood Pressure

scientific article published on 5 September 2017

The Role of FTO Genotype in the Association Between FTO Gene Expression and Anthropometric Measures in Obese and Overweight Adolescent Boys

article

The association of inflammatory and fibrinolytic proteins with 5 year change in insulin clearance: the Insulin Resistance Atherosclerosis Study (IRAS) ⬇️

scientific article published on October 10, 2012

The chromosome 9p21 variant not predicting long-term cardiovascular mortality in Chinese with established coronary artery disease: an eleven-year follow-up study

scientific article published on 02 April 2014

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The importance of insulin resistance in polycystic ovary syndrome

scientific article

The lipoprotein lipase (LPL) S447X gain of function variant involves increased mRNA translation

scientific article published on 27 December 2011

The predictive role of blood glucose for mortality in subjects with cardiovascular disease

scientific article published on 22 December 2005

Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin

scientific article

Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population

scientific article published on 08 September 2013

Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource

scientific article

Type 2 diabetes susceptibility single-nucleotide polymorphisms are not associated with polycystic ovary syndrome

scientific article

Type 3c (pancreatogenic) diabetes mellitus secondary to chronic pancreatitis and pancreatic cancer

scientific article

Up-regulation of FTO gene expression was associated with increase in skeletal muscle mass in overweight male adolescents

scientific article published on 04 September 2019

Up-regulation of microRNA-202-3p in first trimester placenta of pregnancies destined to develop severe preeclampsia, a pilot study

scientific article

Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate

scientific article

Variants in the 5alpha-reductase type 1 and type 2 genes are associated with polycystic ovary syndrome and the severity of hirsutism in affected women

scientific article published on 18 July 2006

Variants in the HMG-CoA reductase (HMGCR) gene influence component phenotypes in polycystic ovary syndrome

scientific article

Variants of the caveolin-1 gene: a translational investigation linking insulin resistance and hypertension

scientific article

Variation in the gene for muscle-specific AMP deaminase is associated with insulin clearance, a highly heritable trait

scientific article published in April 2005

Virilization in bilateral macronodular adrenal hyperplasia controlled by luteinizing hormone

scientific article

Visual vignette. Idiopathic diabetes insipidus.

scientific article published in July 2002

beta-Cell function: a key pathological determinant in polycystic ovary syndrome

scientific article published on 26 October 2004

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