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List of works by Hiroji Iwata

2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy

scientific article

A case of HER2-positive male breast cancer with lung metastases showing a good response to trastuzumab and paclitaxel treatment

scientific article published on 12 June 2008

A case of giant cell tumor of the breast, clinically suspected as malignant breast tumor

A case of invasive micropapillary carcinoma of the breast

scientific article published on 01 January 2007

A case of radiation-associated angiosarcoma after breast cancer

scientific article published on 07 November 2018

A functional single nucleotide polymorphism in ABCC11, rs17822931, is associated with the risk of breast cancer in Japanese

scientific article published on 01 June 2019

A genetic risk predictor for breast cancer using a combination of low-penetrance polymorphisms in a Japanese population

A multi-national, randomised, open-label, parallel, phase III non-inferiority study comparing NK105 and paclitaxel in metastatic or recurrent breast cancer patients

scientific article published on 12 February 2019

A multicenter phase II study of TSU-68, a novel oral multiple tyrosine kinase inhibitor, in patients with metastatic breast cancer progressing despite prior treatment with an anthracycline-containing regimen and taxane

scientific article

A multicenter phase II study of TSU-68, an oral multiple tyrosine kinase inhibitor, in combination with docetaxel in metastatic breast cancer patients with anthracycline resistance.

scientific article

A phase I/II pharmacokinetics/pharmacodynamics study of irinotecan combined with S-1 for recurrent/metastatic breast cancer in patients with selected UGT1A1 genotypes (the JBCRG-M01 study).

scientific article published on 13 November 2017

A phase II study of lapatinib for brain metastases in patients with HER2-overexpressing breast cancer following trastuzumab based systemic therapy and cranial radiotherapy: subset analysis of Japanese patients

scientific article published on 19 July 2012

A randomized controlled trial comparing primary tumour resection plus systemic therapy with systemic therapy alone in metastatic breast cancer (PRIM-BC): Japan Clinical Oncology Group Study JCOG1017

scientific article published on 24 July 2012

A randomized phase II study evaluating pyridoxine for the prevention of hand-foot syndrome associated with capecitabine therapy for advanced or metastatic breast cancer

scientific article published on 08 June 2018

A randomized, double-blind, controlled study of exemestane versus anastrozole for the first-line treatment of postmenopausal Japanese women with hormone-receptor-positive advanced breast cancer ⬇️

scientific article published on May 30, 2013

A randomized, open-label, Phase III trial of pertuzumab retreatment in HER2-positive locally advanced/metastatic breast cancer patients previously treated with pertuzumab, trastuzumab and chemotherapy: the Japan Breast Cancer Research Group-M05 PREC

scientific article published on 01 September 2018

A single-arm, phase 2 study of steroid-containing mouthwash for the prevention of everolimus-associated stomatitis in multiple tumor types

scientific article published on 01 June 2019

A49T, V89L and TA repeat polymorphisms of steroid 5alpha-reductase type II and breast cancer risk in Japanese women

scientific article

ASO Author Reflections: The Strengths and Weaknesses of Intraoperative Radiotherapy for Early Breast Cancer and Ipsilateral Tumor Recurrence

scientific article published on 29 July 2019

Absence of the caveolin-1 P132L mutation in cancers of the breast and other organs

scientific article

Acute phase dynamics of circulating tumor cells after paclitaxel and doxorubicin chemotherapy in breast cancer mouse models

scientific article published on 12 October 2017

Adjuvant Capecitabine for Breast Cancer after Preoperative Chemotherapy

scientific article published on June 2017

Adjuvant S-1 plus endocrine therapy for oestrogen receptor-positive, HER2-negative, primary breast cancer: a multicentre, open-label, randomised, controlled, phase 3 trial

scientific article published on 01 January 2021

Adjuvant and neoadjuvant therapy for breast cancer

scientific article published on 01 March 2020

Adjuvant denosumab in early breast cancer (D-CARE): an international, multicentre, randomised, controlled, phase 3 trial

scientific article published on 02 December 2019

Advances in treatment and care in metastatic breast cancer (MBC): are there MBC patients who are curable?

scientific article published on 28 May 2018

Alcohol and dietary folate intake and the risk of breast cancer: a case-control study in Japan

scientific article published in July 2013

Alcohol consumption and survival after a breast cancer diagnosis: a literature-based meta-analysis and collaborative analysis of data for 29,239 cases

scientific article

Alpelisib for PIK3CA-Mutated, Hormone Receptor-Positive Advanced Breast Cancer

scientific article published on 01 May 2019

Amyloid tumor of the breast

scientific article published on 19 February 2019

Analysis of Ki-67 expression with neoadjuvant anastrozole or tamoxifen in patients receiving goserelin for premenopausal breast cancer.

scientific article published on 12 September 2012

Analysis of subsequent therapy in Japanese patients with hormone receptor‒positive/human epidermal growth factor receptor 2‒negative advanced breast cancer who received palbociclib plus endocrine therapy in PALOMA-2 and -3

scientific article published on 21 October 2020

Anastrozole versus tamoxifen as adjuvant therapy for Japanese postmenopausal patients with hormone-responsive breast cancer: efficacy results of long-term follow-up data from the N-SAS BC 03 trial.

scientific article

Anti-angiogenic therapy for breast cancer--problems and future directions

scientific article published on 01 September 2012

Antitumor Activity and Safety of Trastuzumab Deruxtecan in Patients With HER2-Low-Expressing Advanced Breast Cancer: Results From a Phase Ib Study

scientific article published on 14 February 2020

Application of a continual reassessment method to a phase I clinical trial of capecitabine in combination with cyclophosphamide and epirubicin (CEX) for inoperable or recurrent breast cancer

scientific article published in February 2004

Assessing residual cancer cells using MRI and US after preoperative chemotherapy in primary breast cancer to omit surgery.

scientific article published on 4 April 2018

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy

scientific article

Association analysis identifies 65 new breast cancer risk loci.

scientific article published on 23 October 2017

Association between vitamin D and calcium intake and breast cancer risk according to menopausal status and receptor status in Japan

scientific article published on 12 January 2010

Association of Parity and Infant Feeding Method with Breast Density on Mammography

scientific article published on 06 May 2019

Association of TP53 codon 72 polymorphism and the outcome of adjuvant therapy in breast cancer patients

scientific article published in January 2007

Association of a polymorphism of the phospholipase D2 gene with the prevalence of colorectal cancer

scientific article published on 11 February 2003

Association of p53 codon Arg72Pro and p73 G4C14-to-A4T14 at exon 2 genetic polymorphisms with the risk of Japanese breast cancer.

scientific article published on January 2003

Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer

Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer

Atezolizumab plus nab-paclitaxel as first-line treatment for unresectable, locally advanced or metastatic triple-negative breast cancer (IMpassion130): updated efficacy results from a randomised, double-blind, placebo-controlled, phase 3 trial

scientific article published on 27 November 2019

Author reply: Brief screening of breast cancer survivors with distressing fear of recurrence

scientific article published on 25 February 2016

Bone Scan Index predicts skeletal-related events in patients with metastatic breast cancer

scientific article published on 16 July 2016

Breast cancer risk and erythrocyte compositions of n-3 highly unsaturated fatty acids in Japanese

scientific article published on July 2007

Breast-specific expression of MGB1/mammaglobin: an examination of 480 tumors from various organs and clinicopathological analysis of MGB1-positive breast cancers

scientific article

Brief screening of patients with distressing fear of recurrence in breast cancer survivors

scientific article

Buparlisib plus fulvestrant versus placebo plus fulvestrant for postmenopausal, hormone receptor-positive, human epidermal growth factor receptor 2-negative, advanced breast cancer: Overall survival results from BELLE-2.

scientific article

Buparlisib plus fulvestrant versus placebo plus fulvestrant in postmenopausal, hormone receptor-positive, HER2-negative, advanced breast cancer (BELLE-2): a randomised, double-blind, placebo-controlled, phase 3 trial.

scientific article

Changes in Recurrence Score by neoadjuvant endocrine therapy of breast cancer and their prognostic implication

scientific article published on 27 February 2019

Circulating tumor cells as a prognostic marker for efficacy in the randomized phase III JO21095 trial in Japanese patients with HER2-negative metastatic breast cancer

scientific article published on 8 February 2017

Circulating tumor cells detection in tumor draining vein of breast cancer patients

scientific article published on 03 December 2019

Clinical development of CDK4/6 inhibitor for breast cancer

scientific article

Clinical significance of the 21-gene signature (Oncotype DX) in hormone receptor-positive early stage primary breast cancer in the Japanese population

scientific article published in July 2010

Clinical significance of the expression of autophagy-associated marker, beclin 1, in breast cancer patients who received neoadjuvant endocrine therapy ⬇️

scientific article

Clinical significance of the expression of estrogen receptors alpha and beta for endocrine therapy of breast cancer

scientific article

Clinical usefulness of oral combination chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR) and cyclophosphamide for metastatic breast cancer

scientific article published on 01 January 2006

Combination of subareolar blue dye and peritumoral RI for sentinel lymph node biopsy

scientific article published in January 2002

Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls

scientific article published on 27 March 2013

Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium

scientific article

Comparison of an AC-taxane versus AC-free regimen and paclitaxel versus docetaxel in patients with lymph node-positive breast cancer: Final results of the National Surgical Adjuvant Study of Breast Cancer 02 trial, a randomized comparative phase 3 s

scientific article published on 12 January 2017

Comparison of clinical outcomes between luminal invasive ductal carcinoma and luminal invasive lobular carcinoma

scientific article

Comparison of different definitions of pathologic complete response in operable breast cancer: a pooled analysis of three prospective neoadjuvant studies of JBCRG.

scientific article

Comparison of immune microenvironments between primary tumors and brain metastases in patients with breast cancer

scientific article published on 27 October 2017

Comparison of sentinel lymph node biopsy between invasive lobular carcinoma and invasive ductal carcinoma

scientific article published on 13 March 2018

Contribution of problem-solving skills to fear of recurrence in breast cancer survivors.

scientific article published on 30 March 2014

Correction to: Histological classification of breast tumors in the General Rules for Clinical and Pathological Recording of Breast Cancer (18th edition)

scientific article published on 19 May 2020

Correction to: Neutropenia management with palbociclib in Japanese patients with advanced breast cancer

scientific article published on 01 September 2019

Correction to: Phase I dose-finding study of eribulin and capecitabine for metastatic breast cancer: JBCRG-18 cape study

scientific article published on 20 November 2017

Corrigendum to: Subgroup analysis of Japanese patients in a Phase 3 study of atezolizumab in advanced triple-negative breast cancer (IMpassion130)

scientific article published on 01 February 2020

Current Status of Advance Care Planning and End-of-life Communication for Patients with Advanced and Metastatic Breast Cancer

scientific article published on 15 December 2020

Current approach and future perspective for ductal carcinoma in situ of the breast

scientific article published on 09 May 2017

Current status of PD-1/PD-L1 blockade immunotherapy in breast cancer

scientific article published on 15 December 2020

Current status of postmastectomy radiation therapy in T1-2 breast cancer with limited positive lymph nodes in Japan: Japan Clinical Oncology Group Survey

scientific article published on 23 March 2018

Cytoplasmic expression of the JM403 antigen GlcA-GlcNH3+ on heparan sulfate glycosaminoglycan in mammary carcinomas--a novel proliferative biomarker for breast cancers with high malignancy.

scientific article

Detection of parasternal metastatic lymph nodes by sentinel lymph node methods in a patient with recurrence in the conserved breast ⬇️

scientific article published on 07 January 2011

Detection of presumed germline pathogenic variants of hereditary breast cancer predisposition genes in circulating tumor DNA: SCRUM-Japan MONSTAR-SCREEN.

scientific article published on 06 June 2022

Development of a new rapid isolation device for circulating tumor cells (CTCs) using 3D palladium filter and its application for genetic analysis

scientific article

Dietary patterns and the risk of breast cancer in Japanese women

scientific article published on 11 July 2007

Differential impact of body mass index and its change on the risk of breast cancer by molecular subtype: A case-control study in Japanese women

scientific article published on 23 October 2012

Differential survival following trastuzumab treatment based on quantitative HER2 expression and HER2 homodimers in a clinic-based cohort of patients with metastatic breast cancer

scientific article

Distinct gene expression profiles between primary breast cancers and brain metastases from pair-matched samples

scientific article published on 16 September 2019

Docetaxel Followed by Fluorouracil/Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy for Patients with Primary Breast Cancer ⬇️

scientific article published on July 1, 2011

Dose-dense adjuvant chemotherapy: a systematic review and meta-analysis of the Japanese Breast Cancer Society Clinical Practice Guideline, 2018 edition

scientific article published on 08 January 2020

Dose-finding phase I and pharmacokinetic study of capecitabine (Xeloda) in combination with epirubicin and cyclophosphamide (CEX) in patients with inoperable or metastatic breast cancer

scientific article

Effect of everolimus on bone marker levels and progressive disease in bone in BOLERO-2.

scientific article published on 19 February 2013

Effect of soybean on breast cancer according to receptor status: a case-control study in Japan

scientific article published in October 2008

Effectiveness of neo-adjuvant systemic therapy with trastuzumab for basal HER2 type breast cancer: results from retrospective cohort study of Japan Breast Cancer Research Group (JBCRG)-C03

scientific article published on 03 July 2018

Effects of neoadjuvant chemotherapy on operative adverse events and chemotherapy and radiotherapy in patients undergoing immediate breast reconstruction

scientific article published on 11 March 2020

Efficacy and safety of low-dose capecitabine plus docetaxel versus single-agent docetaxel in patients with anthracycline-pretreated HER2-negative metastatic breast cancer: results from the randomized phase III JO21095 trial

scientific article published on 22 December 2016

Efficacy of everolimus with exemestane versus exemestane alone in Asian patients with HER2-negative, hormone-receptor-positive breast cancer in BOLERO-2.

scientific article

Efficacy, safety, pharmacokinetics and biomarker findings in patients with HER2-positive advanced or metastatic breast cancer treated with lapatinib in combination with capecitabine: results from 51 Japanese patients treated in a clinical study ⬇️

scientific article published on May 21, 2013

Efficient capturing of circulating tumor cells using a magnetic capture column and a size-selective filter

scientific article published on 12 May 2015

Equivalent cross-relaxation rate imaging for sentinel lymph node biopsy in breast carcinoma

scientific article published in November 2005

Equivalent cross-relaxation rate imaging of axillary lymph nodes in breast cancer

scientific article published in June 2008

Erratum to: Outcomes of trastuzumab therapy in HER2‑positive early breast cancer patients

scientific article published on 01 August 2015

Evaluating the 21-gene assay Recurrence Score® as a predictor of clinical response to 24 weeks of neoadjuvant exemestane in estrogen receptor-positive breast cancer

scientific article published on 8 October 2013

Evaluation of Trastuzumab Without Chemotherapy as a Post-operative Adjuvant Therapy in HER2-positive Elderly Breast Cancer Patients: Randomized Controlled Trial [RESPECT (N-SAS BC07)] ⬇️

scientific article published on February 24, 2011

Everolimus plus exemestane in postmenopausal patients with estrogen-receptor-positive advanced breast cancer - Japanese subgroup analysis of BOLERO -2

scientific article published on January 2015

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

scientific article

FGFR2 intronic polymorphisms interact with reproductive risk factors of breast cancer: results of a case control study in Japan

scientific article published in October 2009

Feasibility of intraoperative radiation therapy for early breast cancer in Japan: a single-center pilot study and literature review ⬇️

scientific article published on September 25, 2012

Feasibility study of contralateral risk-reducing mastectomy with breast reconstruction for breast cancer patients with BRCA mutations in Japan.

scientific article published on 8 March 2018

Final Efficacy Results of Neratinib in HER2-positive Hormone Receptor-positive Early-stage Breast Cancer From the Phase III ExteNET Trial

scientific article published on 06 October 2020

Final results of a safety and efficacy trial of preoperative sequential chemoradiation therapy for the nonsurgical treatment of early breast cancer: Japan Clinical Oncology Group Study JCOG0306.

scientific article published on 12 November 2013

Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus

scientific article

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

scientific article published on 4 February 2015

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

scientific article

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

scientific article

First-line bevacizumab in combination with weekly paclitaxel for metastatic breast cancer: efficacy and safety results from a large, open-label, single-arm Japanese study

scientific article published on 31 July 2011

First-line endocrine therapy for postmenopausal patients with hormone receptor-positive, HER2-negative metastatic breast cancer: a systematic review and meta-analysis

scientific article published on 11 February 2020

Four cases of chylous fistula after breast cancer resection

scientific article published on 01 January 2004

Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind

scientific article

Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers

scientific article published on 27 March 2013

Future treatment strategies for metastatic breast cancer: curable or incurable?

scientific article published on 14 April 2011

GANP protein encoded on human chromosome 21/mouse chromosome 10 is associated with resistance to mammary tumor development.

scientific article published on 9 January 2016

Gemcitabine-induced tumor lysis syndrome caused by recurrent breast cancer in a patient without hemodialysis

scientific article published in November 2013

Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.

scientific article

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

scientific article

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

scientific article published in April 2013

Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium

scientific article published on 9 September 2011

Genome-wide association study in East Asians identifies two novel breast cancer susceptibility loci

scientific article published on 27 June 2016

Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer

scientific journal article

Health-related quality of life and psychological distress during neoadjuvant endocrine therapy with letrozole to determine endocrine responsiveness in postmenopausal breast cancer

scientific article published on 2 April 2014

High recurrence risk and use of adjuvant trastuzumab in patients with small, HER2-positive, node-negative breast cancers

scientific article published on 18 June 2011

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

scientific article

Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium

scientific article

Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants

scientific article published on 05 March 2020

Impact of BMI for clinical outcomes in Japanese breast cancer patients

scientific article published on 01 March 2020

Impact of clinical response to neoadjuvant endocrine therapy on patient outcomes: a follow-up study of JFMC34-0601 multicentre prospective neoadjuvant endocrine trial.

scientific article published on 14 February 2018

Impact of germinal center-associated nuclear protein polymorphisms on breast cancer risk and prognosis in a Japanese population

scientific article published on 27 February 2019

Impact of intraoperative specimen mammography on margins in breast-conserving surgery

scientific article published on 04 July 2016

Impact of intrinsic subtype on predicting axillary lymph node metastasis in breast cancer

scientific article

Impact of prophylactic pyridoxine on occurrence of hand-foot syndrome in patients receiving capecitabine for advanced or metastatic breast cancer.

scientific article published on 30 September 2009

Incidence of contralateral and ipsilateral breast cancers and prognosis in BRCA1/2 pathogenic variant carriers based on the Japanese HBOC Consortium registration

scientific article published on 09 October 2020

Incidence of contralateral breast cancer in Japanese patients with unilateral minimum-risk primary breast cancer, and the benefits of endocrine therapy and radiotherapy

scientific article published on 04 October 2012

Incidence of pneumonitis/interstitial lung disease induced by HER2-targeting therapy for HER2-positive metastatic breast cancer

scientific article published on 26 June 2020

Insulin, insulin-like growth factor-I and breast cancer risk in Japanese women

scientific article published on July 1, 2003

Intensive vs. Standard Post-Operative Surveillance in High-Risk Breast Cancer Patients (INSPIRE): Japan Clinical Oncology Group Study JCOG1204.

scientific article published on 5 August 2015

Interaction of the effects of alcohol drinking and polymorphisms in alcohol-metabolizing enzymes on the risk of female breast cancer in Japan

scientific article published on 08 August 2009

Interim analysis of a phase II trial of cyclophosphamide, epirubicin and 5-fluorouracil (CEF) followed by docetaxel as preoperative chemotherapy for early stage breast carcinoma

scientific article published in January 2005

Ki67 index changes, pathological response and clinical benefits in primary breast cancer patients treated with 24 weeks of aromatase inhibition

scientific article published on 10 February 2011

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

scientific article

Long-term survival analysis of addition of carboplatin to neoadjuvant chemotherapy in HER2-negative breast cancer

scientific article published on 05 March 2020

Low expression of the snail gene is a good prognostic factor in node-negative invasive ductal carcinomas

scientific article published on 09 June 2006

MONARCH 3 final PFS: a randomized study of abemaciclib as initial therapy for advanced breast cancer

scientific article published on 17 January 2019

Mechanisms and anatomical risk factors of pneumothorax after Bevacizumab use: A case report

scientific article published on 01 July 2020

Multi-center study evaluating circulating tumor cells as a surrogate for response to treatment and overall survival in metastatic breast cancer

scientific article published on 01 August 2009

Multicenter Phase II Study of Intraoperative Radiotherapy of Early Breast Cancer: Ipsilateral Tumor Recurrence

scientific article published on 16 April 2019

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism and the risk of eight cancers for Japanese

scientific article

Neo(adjuvant) trastuzumab treatment: current perspectives

scientific article published on 17 July 2009

Neoadjuvant anastrozole versus tamoxifen in patients receiving goserelin for premenopausal breast cancer (STAGE): a double-blind, randomised phase 3 trial ⬇️

scientific article published on January 20, 2012

Neoadjuvant atezolizumab in combination with sequential nab-paclitaxel and anthracycline-based chemotherapy versus placebo and chemotherapy in patients with early-stage triple-negative breast cancer (IMpassion031): a randomised, double-blind, phase

scientific article published on 18 September 2020

Neoadjuvant endocrine therapy for postmenopausal patients with hormone receptor-positive early breast cancer: a new concept

scientific article published on 08 December 2010

Neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): 5-year analysis of a randomised, double-blind, placebo-controlled, phase 3 trial

scientific article published on 13 November 2017

Neratinib after trastuzumab-based adjuvant therapy in patients from Asia with early stage HER2-positive breast cancer

scientific article published on 29 May 2019

Neratinib after trastuzumab-based adjuvant therapy in patients with HER2-positive breast cancer (ExteNET): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

scientific article

Neutropenia management with palbociclib in Japanese patients with advanced breast cancer

scientific article published on 24 May 2019

Occult breast cancer may originate from ectopic breast tissue present in axillary lymph nodes

scientific article published on 20 July 2018

Olaparib monotherapy for Asian patients with a germline BRCA mutation and HER2-negative metastatic breast cancer: OlympiAD randomized trial subgroup analysis

scientific article published on 29 May 2020

Omitting surgery for early breast cancer showing clinical complete response to primary systemic therapy

scientific article published on 07 May 2020

One-carbon metabolism-related gene polymorphisms and risk of breast cancer

scientific article

Oral uracil and tegafur compared with classic cyclophosphamide, methotrexate, fluorouracil as postoperative chemotherapy in patients with node-negative, high-risk breast cancer: National Surgical Adjuvant Study for Breast Cancer 01 Trial

scientific article

Outcomes of Japanese breast cancer patients treated with pre-operative and post-operative anastrozole or tamoxifen

scientific article published on 13 January 2012

Outcomes of trastuzumab therapy in HER2-positive early breast cancer patients

scientific article published on 10 February 2015

Outcomes of trastuzumab therapy in HER2-positive early breast cancer patients: extended follow-up of JBCRG-cohort study 01

scientific article published on 14 February 2020

Overall Survival with Palbociclib and Fulvestrant in Advanced Breast Cancer

PALOMA-3: Phase III Trial of Fulvestrant With or Without Palbociclib in Premenopausal and Postmenopausal Women With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Metastatic Breast Cancer That Progressed on Prior Endocr

scientific article published on 11 April 2017

PIK3CA alterations and benefit with neratinib: analysis from the randomized, double-blind, placebo-controlled, phase III ExteNET trial

article

Palbociclib Combined with Fulvestrant in Premenopausal Women with Advanced Breast Cancer and Prior Progression on Endocrine Therapy: PALOMA-3 Results

scientific article

Palbociclib in Combination With Fulvestrant in Women With Hormone Receptor-Positive/HER2-Negative Advanced Metastatic Breast Cancer: Detailed Safety Analysis From a Multicenter, Randomized, Placebo-Controlled, Phase III Study (PALOMA-3).

scientific article published on July 2016

Palbociclib in Hormone-Receptor-Positive Advanced Breast Cancer

scientific article

Palbociclib in combination with fulvestrant in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: PALOMA-3 subgroup analysis of Japanese patients

scientific article published on 03 November 2018

Palbociclib in combination with letrozole as first-line treatment for advanced breast cancer: a Japanese phase II study.

scientific article published on 18 January 2018

Palbociclib in combination with letrozole in patients with estrogen receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer: PALOMA-2 subgroup analysis of Japanese patients

scientific article published on 04 December 2018

Palbociclib-letrozole as first-line treatment for advanced breast cancer: Updated results from a Japanese phase 2 study

scientific article published on 18 May 2020

Pathway analyses identify TGFBR2 as potential breast cancer susceptibility gene: results from a consortium study among Asians

scientific article published on 26 April 2012

Patient-reported outcomes and objective assessments with arm measurement and bioimpedance analysis for lymphedema among breast cancer survivors

scientific article published on 18 September 2019

Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (KEYNOTE-355): a randomised, placebo-controlled, double-blind, phase 3 clinical trial

scientific article published on 01 December 2020

Perspective of trastuzumab treatment

scientific article published on January 2007

Pharmacogenomic-pharmacokinetic study of selective estrogen-receptor modulators with intra-patient dose escalation in breast cancer

scientific article published on 07 February 2019

Phase 2 study of pembrolizumab (pembro) monotherapy for previously treated metastatic triple-negative breast cancer (mTNBC): KEYNOTE-086 cohort A

Phase 2 study of pembrolizumab as first-line therapy for PD-L1–positive metastatic triple-negative breast cancer (mTNBC): Preliminary data from KEYNOTE-086 cohort B

Phase I and pharmacokinetic study of trastuzumab emtansine in Japanese patients with HER2-positive metastatic breast cancer

scientific article

Phase I dose-finding study of eribulin and capecitabine for metastatic breast cancer: JBCRG-18 cape study

scientific article

Phase II study of gemcitabine monotherapy as a salvage treatment for Japanese metastatic breast cancer patients after anthracycline and taxane treatment

scientific article published on 22 September 2009

Phase II study of preoperative sequential FEC and docetaxel predicts of pathological response and disease free survival

scientific article published on 19 September 2007

Phase II study of preoperative systemic treatment with the combination of docetaxel and trastuzumab in patients with locally advanced HER-2-overexpressing breast cancer

scientific article published on 15 May 2010

Phase III randomized adjuvant study of tamoxifen alone versus sequential tamoxifen and anastrozole in Japanese postmenopausal women with hormone-responsive breast cancer: N-SAS BC03 study

scientific article published in June 2010

Phase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer

scientific article

Phase III, Randomized Study of Dual Human Epidermal Growth Factor Receptor 2 (HER2) Blockade With Lapatinib Plus Trastuzumab in Combination With an Aromatase Inhibitor in Postmenopausal Women With HER2-Positive, Hormone Receptor-Positive Metastatic

scientific article published on 15 December 2017

Phase III, Randomized Study of Dual Human Epidermal Growth Factor Receptor 2 (HER2) Blockade With Lapatinib Plus Trastuzumab in Combination With an Aromatase Inhibitor in Postmenopausal Women With HER2-Positive, Hormone Receptor-Positive Metastatic

scientific article published on 21 August 2020

Polymorphism of dihydropyrimidine dehydrogenase (DPYD) Cys29Arg and risk of six malignancies in Japanese.

scientific article published in June 2005

Prediction of pathological margin status using preoperative contrast-enhanced MRI in patients with early breast cancer who underwent skin-sparing mastectomy

scientific article published on 30 January 2019

Prediction of postoperative disease-free survival and brain metastasis for HER2-positive breast cancer patients treated with neoadjuvant chemotherapy plus trastuzumab using a machine learning algorithm

scientific article published on 07 September 2018

Preoperative endocrine therapy as a predictive biomarker of adjuvant chemotherapy

scientific article published on 01 October 2017

Presence of small residual malignant lesions in pathologic complete response after neo-adjuvant chemotherapy in patients with breast cancer

scientific article published on 18 July 2019

Prognostic factors of HER2-positive breast cancer patients who develop brain metastasis: a multicenter retrospective analysis

scientific article published on 21 December 2014

Prognostic significance of subtype and pathologic response in operable breast cancer; a pooled analysis of prospective neoadjuvant studies of JBCRG.

scientific article published on 14 December 2013

Psychometric properties of the Japanese version of the Concerns About Recurrence Scale (CARS-J).

scientific article published on 7 April 2014

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

scientific article published on 10 April 2018

Rainbow of KIBOU (ROK) study: a Breast Cancer Survivor Cohort in Japan

scientific article published on 25 May 2017

Randomized Controlled Trial of Trastuzumab With or Without Chemotherapy for HER2-Positive Early Breast Cancer in Older Patients

scientific article published on 16 September 2020

Randomized controlled trial of toremifene 120 mg compared with exemestane 25 mg after prior treatment with a non-steroidal aromatase inhibitor in postmenopausal women with hormone receptor-positive metastatic breast cancer ⬇️

scientific article published on May 16, 2013

Randomized phase II study of nab-paclitaxel as first-line chemotherapy in patients with HER2-negative metastatic breast cancer.

scientific article

Randomized phase II study of primary systemic chemotherapy and trastuzumab for operable HER2 positive breast cancer.

scientific article

Randomized phase II study of three doses of oral TAS‐108 in postmenopausal patients with metastatic breast cancer ⬇️

scientific article published on July 16, 2012

Randomized phase II study of weekly paclitaxel with and without carboplatin followed by cyclophosphamide/epirubicin/5-fluorouracil as neoadjuvant chemotherapy for stage II/IIIA breast cancer without HER2 overexpression

scientific article published on 12 April 2014

Re: Population-based, case-control study of HER2 genetic polymorphism and breast cancer risk

scientific article published in December 2002

Recent Improvement in the Long-term Survival of Breast Cancer Patients by Age and Stage in Japan.

scientific article published on 24 February 2018

Relationship between body mass index and preoperative treatment response to aromatase inhibitor exemestane in postmenopausal patients with primary breast cancer ⬇️

scientific article published on August 19, 2011

Replication and functional genomic analyses of the breast cancer susceptibility locus at 6q25.1 generalize its importance in women of chinese, Japanese, and European ancestry

scientific article

Reply to T.J.A. Dekker

scientific article published on 13 July 2020

Results of survey conducted on perioperative chemotherapy and supportive care in primary breast cancer (JBCRG01)

scientific article published in October 2007

Risks and benefits of bevacizumab combined with chemotherapy for advanced or metastatic breast cancer: a meta-analysis of randomized controlled trials

scientific article published on 23 January 2020

Safety and effectiveness of eribulin in Japanese patients with locally advanced or metastatic breast cancer: a post-marketing observational study

scientific article published on 29 June 2017

Safety and pharmacokinetics of ramucirumab in combination with docetaxel in Japanese patients with locally advanced or metastatic breast cancer: a Phase Ib study

scientific article published on 8 September 2016

Safety, pharmacokinetics and efficacy findings in an open-label, single-arm study of weekly paclitaxel plus lapatinib as first-line therapy for Japanese women with HER2-positive metastatic breast cancer

scientific article

Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Patients With an Initial Diagnosis of Cytology-Proven Lymph Node-Positive Breast Cancer

scientific article published on 11 February 2016

Sentinel lymph node biopsy is not necessary in patients diagnosed with ductal carcinoma in situ of the breast by stereotactic vacuum-assisted biopsy

scientific article published on 03 July 2014

Serum concentration of the CKD4/6 inhibitor abemaciclib, but not of creatinine, strongly predicts hematological adverse events in patients with breast cancer: a preliminary report

scientific article published on 27 August 2020

Significance of primary lesion resection in Stage IV breast cancer

scientific article published on 23 February 2017

Significant Reduction in Breast Cancer Risk for Japanese Women with Interleukin 1B -31 CT/TT Relative to CC Genotype

scientific article published on 01 October 2002

Smartphone problem-solving and behavioural activation therapy to reduce fear of recurrence among patients with breast cancer (SMartphone Intervention to LEssen fear of cancer recurrence: SMILE project): protocol for a randomised controlled trial

scientific article published on 08 November 2018

Study protocol for a nationwide questionnaire survey of physical activity among breast cancer survivors in Japan

scientific article published on 20 January 2020

Subgroup analysis of Japanese patients in a Phase 3 study of atezolizumab in advanced triple-negative breast cancer (IMpassion130)

scientific article published on 01 December 2019

TNM classification of malignant tumors (Breast Cancer Study Group)

scientific article published on 01 March 2019

Tamoxifen plus tegafur-uracil (TUFT) versus tamoxifen plus Adriamycin (doxorubicin) and cyclophosphamide (ACT) as adjuvant therapy to treat node-positive premenopausal breast cancer (PreMBC): results of Japan Clinical Oncology Group Study 9404

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Tamoxifen versus tamoxifen plus doxorubicin and cyclophosphamide as adjuvant therapy for node-positive postmenopausal breast cancer: results of a Japan Clinical Oncology Group Study (JCOG9401).

scientific article published on 7 January 2014

Targeting HER2 with Trastuzumab Deruxtecan: A Dose-Expansion, Phase I Study in Multiple Advanced Solid Tumors

scientific article published on 25 March 2020

The CYP19 gene codon 39 Trp/Arg polymorphism increases breast cancer risk in subsets of premenopausal Japanese.

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The Japanese Breast Cancer Society Clinical Practice Guideline for radiation treatment of breast cancer, 2018 edition

scientific article published on 28 October 2019

The Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer Screening and Diagnosis, 2018 Edition

scientific article published on 16 November 2019

The Japanese Breast Cancer Society Clinical Practice Guidelines for systemic treatment of breast cancer, 2018 edition ⬇️

scientific article published on 02 April 2020

The Japanese Breast Cancer Society Clinical Practice Guidelines, 2018 edition: the tool for shared decision making between doctor and patient

scientific article published on 22 November 2019

The Japanese Breast Cancer Society clinical practice guidelines for surgical treatment of breast cancer, 2018 edition

scientific article published on 12 December 2019

The Transition of Breast Cancer Treatment and Japan Clinical Oncology Group Research Over Two Decades ⬇️

scientific article published on November 11, 2011

The investigation study using a questionnaire about the employment of Japanese breast cancer patients

scientific article published on 01 August 2018

The overall survival of breast cancer patients without adjuvant therapy

scientific article published on 07 February 2019

The utility of DHL-HisZnNa, a novel antioxidant, against anticancer agent-induced alopecia in breast cancer patients: a multicenter phase II clinical trial

scientific article published on 26 February 2019

Transforming growth factor B1 T29C polymorphism and breast cancer risk in Japanese women

scientific article published on 01 January 2003

Trastuzumab Deruxtecan in Previously Treated HER2-Positive Breast Cancer

scientific article published on 11 December 2019

Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer

scientific article

Trastuzumab and vinorelbine as first-line therapy for HER2-overexpressing metastatic breast cancer: multicenter phase II and pharmacokinetic study in Japan

scientific article published in August 2008

Trastuzumab deruxtecan (DS-8201a) in patients with advanced HER2-positive breast cancer previously treated with trastuzumab emtansine: a dose-expansion, phase 1 study

article published in 2019

Trastuzumab deruxtecan (DS-8201a) in patients with advanced HER2-positive gastric cancer: a dose-expansion, phase 1 study

scientific article published on 29 April 2019

Trastuzumab deruxtecan (DS-8201a) in subjects with HER2-expressing solid tumors: Long-term results of a large phase 1 study with multiple expansion cohorts

Trastuzumab emtansine plus pertuzumab in Japanese patients with HER2-positive metastatic breast cancer: a phase Ib study

scientific article published on 23 July 2018

Trastuzumab-associated cardiac adverse effects in the herceptin adjuvant trial.

scientific article published on 23 July 2007

Treatment Strategy in Patients with Oligometastatic Breast Cancer

scientific article published in October 2017

Treatment outcomes and prognostic factors for patients with brain metastases from breast cancer of each subtype: a multicenter retrospective analysis

scientific article published on 9 August 2014

Utility of regional nodal irradiation in Japanese patients with breast cancer with 1-3 positive nodes after breast-conserving surgery and axillary lymph-node dissection

scientific article published on 18 May 2020

Validation of the 21-gene test as a predictor of clinical response to neoadjuvant hormonal therapy for ER+, HER2-negative breast cancer: the TransNEOS study.

scientific article published on 21 September 2018

[A Phase I Combination Dose-Escalation Study of Eribulin Mesylate and Gemcitabine in Japanese Patients with Metastatic Breast Cancer]

scientific article published on 01 August 2018

[Current situation and features of chemotherapy for breast neoplasms]

scientific article published on 01 June 2007

[Effectiveness of breast ultrasound]

scientific article published on 01 June 2007

[Results of a drug use investigation of nanoparticle albumin-bound Paclitaxel for breast cancer]

article by Seigo Nakamura et al published 1 April 2015 in Japanese Journal of Cancer and Chemotherapy

＜Editors' Choice＞ Practice management for elderly patients with breast cancer; Findings from a survey by the Japan Breast Cancer Study Group.

scientific article

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