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List of works by Peter Kovacs

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A central role for GRB10 in regulation of islet function in man.

scientific article published on 3 April 2014

A common variant of PNPLA3 (p.I148M) is not associated with alcoholic chronic pancreatitis

scientific article

A functional Tyr1306Cys variant in LARG is associated with increased insulin action in vivo

scientific article published on May 2006

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

ADCY5 gene expression in adipose tissue is related to obesity in men and mice

scientific article

Adipose tissue depot specific promoter methylation of TMEM18.

scientific article published on 26 April 2014

Adipose tissue derived bacteria are associated with inflammation in obesity and type 2 diabetes

scientific article published on 21 April 2020

Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity

scientific article published on 05 June 2009

Age- and gender-specific norms for the German version of the Three-Factor Eating-Questionnaire (TFEQ).

scientific article published on 15 April 2015

Alleles of the Spontaneously Hypertensive Rat Decrease Blood Pressure at Loci on Chromosomes 4 and 13 ⬇️

scientific article published on September 18, 1997

Altered sex ratio in offspring of mothers with insulin-dependent diabetes mellitus ⬇️

scientific article published on February 14, 1998

An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects

scientific article

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

Analysis of a rare functional truncating mutation rs61757459 in vaspin (SERPINA12) on circulating vaspin levels

scientific article published on 12 June 2013

Apolipoprotein E allele frequencies in chronic and self-limited hepatitis C suggest a protective effect of APOE4 in the course of hepatitis C virus infection

scientific article

Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany

scientific article published on January 2010

Blurring the picture in leaky gut research: how shortcomings of zonulin as a biomarker mislead the field of intestinal permeability

scientific article published on 09 October 2020

Bone morphogenetic protein 2 (BMP2) may contribute to partition of energy storage into visceral and subcutaneous fat depots

scientific article

Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation

scientific article

C57BL/6JRj mice are protected against diet induced obesity (DIO).

scientific article published on 8 December 2011

CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated?

scientific article published on 17 March 2012

CYP2C metabolism of oral antidiabetic drugs - impact on pharmacokinetics, drug interactions and pharmacogenetic aspects ⬇️

scientific article published on December 1, 2012

Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis

scientific article

Circulating bacterial signature is linked to metabolic disease and shifts with metabolic alleviation after bariatric surgery

scientific article published on 22 June 2021

Combined Proteomic and Metabolomic Profiling of Serum Reveals Association of the Complement System with Obesity and Identifies Novel Markers of Body Fat Mass Changes ⬇️

scientific article published on August 29, 2011

Common genetic variation near MC4R has a sex-specific impact on human brain structure and eating behavior

scientific article

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways ⬇️

scientific article

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Comparison of genetic variability at microsatellite loci in wild rats and inbred rat strains (Rattus norvegicus) ⬇️

scientific article published on 01 August 1997

Complete analysis of the human mesotrypsinogen gene (PRSS3) in patients with chronic pancreatitis

scientific article

Congenic strain confirms putative quantitative trait locus for body weight in the rat ⬇️

scientific article published on April 1, 1998

Contemporary paternal genetic landscape of Polish and German populations: from early medieval Slavic expansion to post-World War II resettlements

scientific article (publication date: 12 September 2012)

Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children

scientific article published in May 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Crosses between diabetic BB/OK and wild rats confirm that a third gene is essential for diabetes development ⬇️

scientific article published on July 1, 1998

DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial

scientific article published on 16 November 2020

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

scientific article

Di-(2-Ethylhexyl)-Phthalate (DEHP) Causes Impaired Adipocyte Function and Alters Serum Metabolites

scientific article (publication date: 2015)

Diabetes and Hypertension in Rodent Modelsa ⬇️

scientific article published on September 20, 1997

ENPP1Variants and Haplotypes Predispose to Early Onset Obesity and Impaired Glucose and Insulin Metabolism in German Obese Children

article

Eating Behaviour in the General Population: An Analysis of the Factor Structure of the German Version of the Three-Factor-Eating-Questionnaire (TFEQ) and Its Association with the Body Mass Index

scientific article published on 31 July 2015

Effect of genetic variation in the human fatty acid synthase gene (FASN) on obesity and fat depot-specific mRNA expression

scientific article published on 29 October 2009

Effects of SLC10A2 variant rs9514089 on gallstone risk and serum cholesterol levels- meta-analysis of three independent cohorts

scientific article

Effects of Weight Loss on Glutathione Peroxidase 3 Serum Concentrations and Adipose Tissue Expression in Human Obesity

Effects of genetic variants in ADCY5, GIPR, GCKR and VPS13C on early impairment of glucose and insulin metabolism in children

scientific article

Effects of genetic variation in the human retinol binding protein-4 gene (RBP4) on insulin resistance and fat depot-specific mRNA expression

scientific article published on 29 August 2007

Effects of genetic variation in the visfatin gene (PBEF1) on obesity, glucose metabolism, and blood pressure in children

article

Effects of psychological eating behaviour domains on the association between socio-economic status and BMI.

scientific article

Effects of resveratrol on memory performance, hippocampus connectivity and microstructure in older adults - A randomized controlled trial

scientific article published on 13 March 2018

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Evaluation of A2BP1 as an obesity gene ⬇️

scientific article

Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes

scientific article published on 7 May 2016

FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children - Relevance of FTO Variants to Defend Body Weight in Lean Children?

scientific article

Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits

scientific article published on 9 December 2015

Fatty acids and insulin resistance in muscle and liver

scientific article

Fibroblast growth factor-21 serum concentrations are associated with metabolic and hepatic markers in humans

scientific article published on 18 January 2013

Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism

scientific article published on 08 December 2016

Gene expression patterns of vascular endothelial growth factor (VEGF-A) in human placenta from pregnancies with intrauterine growth restriction ⬇️

scientific article published on February 13, 2013

Genes of the Immune System Cosegregate with the Age at Onset of Diabetes in the BB/OK Rat ⬇️

scientific article published on January 14, 1998

Genetic Contribution of Variants near SORT1 and APOE on LDL Cholesterol Independent of Obesity in Children

scientific article published on 16 September 2015

Genetic analyses of bone morphogenetic protein 2, 4 and 7 in congenital combined pituitary hormone deficiency.

scientific article

Genetic analyses of heme oxygenase 1 (HMOX1) in different forms of pancreatitis

scientific article

Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression

scientific article published on 5 July 2013

Genetic and evolutionary analyses of the human bone morphogenetic protein receptor 2 (BMPR2) in the pathophysiology of obesity

scientific article

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic evidence of assortative mating in humans

scholarly article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants in AKR1B10 associate with human eating behavior

scientific article

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs

scientific article published on 03 September 2009

Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity

scientific article

Genetic variation in the human winged helix/forkhead transcription factor gene FOXC2 in Pima Indians

scientific article

Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat-depot-specific messenger ribonucleic acid expression in humans

scientific article published on 24 April 2006

Genetically programmed changes in transcription of the novel progranulin regulator

scientific article published on 03 July 2020

Genetics of adiponectin

scientific article published on 15 March 2012

Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin

scientific article

Genome wide meta-analysis identifies novel determinants of circulating serum progranulin

scientific article published on 27 November 2017

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

scientific article published on 14 July 2016

Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity

scientific article

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

scientific article published on 11 September 2019

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

scientific article

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis

scientific article

Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A.

scientific article

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits ⬇️

scientific article published on 21 June 2016

Genomic insights into the origin of farming in the ancient Near East

scientific article (publication date: 25 August 2016)

Global DNA methylation levels in human adipose tissue are related to fat distribution and glucose homeostasis

scientific article published on 22 August 2014

Gut Microbiome, Intestinal Permeability, and Tissue Bacteria in Metabolic Disease: Perpetrators or Bystanders?

scientific article published on 14 April 2020

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Hypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunction

scientific article published on 27 June 2016

IRS1 DNA promoter methylation and expression in human adipose tissue are related to fat distribution and metabolic traits

scientific article published on 28 September 2017

Identification of distinct transcriptome signatures of human adipose tissue from fifteen depots

scientific article published on 13 July 2020

Identification of genetic loci associated with different responses to high-fat diet-induced obesity in C57BL/6N and C57BL/6J substrains

scientific article published in April 2014

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

scientific article published on 12 September 2017

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article

Insulin administration acutely decreases vaspin serum concentrations in humans.

scientific article published on 2 March 2013

Insulin-sensitive obesity

scientific article published on 22 June 2010

Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood

scientific article

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Involvement of the chemokine-like receptor GPR33 in innate immunity

scientific article

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Liver-restricted Repin1 deficiency improves whole-body insulin sensitivity, alters lipid metabolism, and causes secondary changes in adipose tissue in mice

scientific article

Long-term exercise training decreases interleukin-6 (IL-6) serum levels in subjects with impaired glucose tolerance: effect of the -174G/C variant in IL-6 gene

scientific article published on 9 May 2008

Mapping of Novel Genes Predisposing or Protecting Diabetes Development in the BB/OK Rat ⬇️

scientific article published on April 17, 1998

Mapping of quantitative trait loci for body weight on chromosomes 1 and 4 in the rat ⬇️

scientific article published on February 1, 1998

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Metabolic and genetic predictors of circulating adipocyte fatty acid-binding protein ⬇️

scientific article published on August 23, 2011

Metabolic effects of genetic variation in the human REPIN1 gene

scientific article published on 18 June 2018

Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity

scientific article published in June 2003

Metabolic features of newly established congenic diabetes-prone BB.SHR rat strains ⬇️

scientific article published on 01 January 1998

MicroRNA expression in human omental and subcutaneous adipose tissue

scientific article

Mutational analysis of the gene encoding the zymogen granule membrane glycoprotein 2 (GP2) in patients with chronic pancreatitis

scientific article

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New loci associated with kidney function and chronic kidney disease

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity

scientific article published in March 2013

No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels

scientific article published on 13 March 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

Number and sex ratio of children and impact of parental diabetes in individuals with Type 1 diabetes ⬇️

scientific article published on October 1, 2012

Obesity genes: implication in childhood obesity

article

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

PTEN regulates adipose progenitor cell growth, differentiation, and replicative aging

scientific article published on 14 July 2021

Phenotype and Genotype Comparison of Hereditary Hypertriglyceridemic (hHTG) and Brown‐Norway (BN) Rats Identification of Quantitative Trait Loci (QTLs) for the Insulin Resistance Syndromea ⬇️

scientific article published on September 20, 1997

Phenotype of a patient with a de novo mutation in the hepatocyte nuclear factor 1beta/maturity-onset diabetes of the young type 5 gene

scientific article

Phenotypic Consequences after Restoration of Lymphopenia in the Diabetes-Prone BB/OK Rat ⬇️

scientific article published on 01 October 1997

Phenotypic differences between diabetes‐prone BB rat sublines cosegregate with loci on chromosomes X and 10 ⬇️

scientific article published on August 1, 1998

Plasma visfatin concentrations and fat depot-specific mRNA expression in humans

scientific article published in October 2005

Polygenic contribution to obesity: genome-wide strategies reveal new targets

scientific article published on January 2008

Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays

scientific article

Preliminary report: circulating levels of the adipokine vaspin in gestational diabetes mellitus and preeclampsia

scientific article published on 31 December 2009

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Quantitative Trait Loci on Chromosomes 1 and 4 Affect Lipid Phenotypes in the Rat ⬇️

scientific article published on 01 June 1998

R1467H variant in the rho guanine nucleotide exchange factor 11 (ARHGEF11) is associated with impaired glucose tolerance and type 2 diabetes in German Caucasians

scientific article published on 31 January 2008

Random Projection for Fast and Efficient Multivariate Correlation Analysis of High-Dimensional Data: A New Approach

scientific article

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Reduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82

scientific article (publication date: 2011)

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Relationship between twelve adipocytokines and distinct components of the metabolic syndrome

scientific article published on 9 January 2018

Repin1 deficiency improves insulin sensitivity and glucose metabolism in db/db mice by reducing adipose tissue mass and inflammation

scientific article published on 8 July 2016

Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes

scientific journal article

Role of genetic variants in ADIPOQ in human eating behavior

scientific article

Role of genetic variation in the cannabinoid type 1 receptor gene (CNR1) in the pathophysiology of human obesity

scientific article published in May 2010

Role of genetic variation in the human sodium-glucose cotransporter 2 gene (SGLT2) in glucose homeostasis

scientific article published on 10 August 2011

Role of vaspin in human eating behaviour

scientific article

SGLT2 : A Potential Target for the Pharmacogenetics of Type 2 Diabetes? ⬇️

scientific article published on May 1, 2013

Sequence analysis of the human tyrosylprotein sulfotransferase-2 gene in subjects with chronic pancreatitis

scientific article

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

scientific article

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption

scientific article

Serum levels of acylcarnitines are altered in prediabetic conditions

scientific article

Serum levels of the adipokine progranulin depend on renal function

scientific article published on October 2012

Severe Hypoglycemia Due to Possible Interaction Between Glibenclamide and Sorafenib in a Patient with Hepatocellular Carcinoma ⬇️

scientific article published on April 1, 2013

Signatures of natural selection at the FTO (fat mass and obesity associated) locus in human populations

scientific article published on 3 February 2015

Substantial increase in incidence of severe hypoglycemia between 1997-2000 and 2007-2010: a German longitudinal population-based study

scientific article published on 12 March 2012

TAS2R38 and its influence on smoking behavior and glucose homeostasis in the German Sorbs

scientific article

TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes

scientific article

TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus

scientific article

TCF7L2 gene polymorphisms confer an increased risk for early impairment of glucose metabolism and increased height in obese children

scientific article published on 20 February 2007

THOC5: a novel gene involved in HDL-cholesterol metabolism

scientific article published on 10 September 2013

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

Targeted SNP Genotyping Using the TaqMan® Assay ⬇️

scientific article published on January 1, 2011

The Effect of FGF21 and Its Genetic Variants on Food and Drug Cravings, Adipokines and Metabolic Traits

scientific article published in 2021

The Glu23Lys polymorphism in KCNJ11 and impaired hypoglycaemia awareness in patients with type 1 diabetes

scientific article

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The Ser1369Ala Variant of ABCC8 and the Risk for Severe Sulfonylurea-Induced Hypoglycemia In German Patients with Type 2 Diabetes ⬇️

scientific article published on 01 January 2012

The effect of ACACB cis-variants on gene expression and metabolic traits

scientific article

The genetic structure of the world's first farmers

The power of genetic diversity in genome-wide association studies of lipids

The role of rs2237781 within GRM8 in eating behavior

scientific article published on 23 June 2013

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups

scientific journal article

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Variants in CPA1 are strongly associated with early onset chronic pancreatitis

scientific article published on 18 August 2013

Variation in FTO contributes to childhood obesity and severe adult obesity

scientific article

Variation of the gene encoding the nuclear bile salt receptor FXR and gallstone susceptibility in mice and humans

scientific article published in October 2007

Vaspin gene expression in human adipose tissue: association with obesity and type 2 diabetes

scientific article

Vaspin inhibits kallikrein 7 by serpin mechanism

scientific article

Voluntary upregulation of heart rate variability through biofeedback is improved by mental contemplative training.

scientific article published on 27 May 2019

WOK.1W rats. A potential animal model of the insulin resistance syndrome ⬇️

scientific article published on September 20, 1997

Widely Used Commercial ELISA Does Not Detect Precursor of Haptoglobin2, but Recognizes Properdin as a Potential Second Member of the Zonulin Family

scientific article published on 5 February 2018

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