Search filters

List of works by Khozirah Shaari

1 H‐NMR metabolomics for evaluating the protective effect of Clinacanthus nutans (Burm. f) Lindau water extract against nitric oxide production in LPS‐IFN‐ γ activated RAW 264.7 macrophages

scientific article published on 05 September 2018

1H-NMR-based metabolomics approach to understanding the drying effects on the phytochemicals in Cosmos caudatus

2-Benzoyl-6-benzylidenecyclohexanone analogs as potent dual inhibitors of acetylcholinesterase and butyrylcholinesterase.

scientific article published on 9 June 2016

A Comprehensive Review on Phytochemistry and Pharmacological Activities of (Burm.f.) Lindau

scientific article published on 04 July 2018

A curcumin derivative, 2,6-bis(2,5-dimethoxybenzylidene)-cyclohexanone (BDMC33) attenuates prostaglandin E2 synthesis via selective suppression of cyclooxygenase-2 in IFN-γ/LPS-stimulated macrophages.

scientific article

A geranyl acetophenone targeting cysteinyl leukotriene synthesis prevents allergic airway inflammation in ovalbumin-sensitized mice

scientific article published on 12 January 2012

A geranylacetophenone from the leaves ofMelicope ptelefolia

scientific article published on 01 May 2006

A labdane diterpene glucoside from the rhizomes of Curcuma mangga.

scientific article published in July 2005

Acetylcholinesterase and α-glucosidase inhibitory compounds from Callicarpa maingayi

scientific article published on 21 October 2019

Adsorption and Desorption Properties of Total Flavonoids from Oil Palm (Elaeis guineensis Jacq.) Mature Leaf on Macroporous Adsorption Resins

scientific article published on 11 February 2020

Alkaloidal constituents of Tinospora crispa

scientific article published on November 1, 2010

Alkenylresorcinols and cytotoxic activity of the constituents isolated from Labisia pumila

scientific article published on 26 May 2012

An orally active geranyl acetophenone attenuates airway remodeling in a murine model of chronic asthma

scientific article published on 12 January 2017

Anthraquinones from Hedyotis capitellata

scientific article published in May 2005

Anti-Diabetic Activity and Metabolic Changes Induced by Andrographis paniculata Plant Extract in Obese Diabetic Rats.

scientific article

Anti-allergic activity of 2,4,6-trihydroxy-3-geranylacetophenone (tHGA) via attenuation of IgE-mediated mast cell activation and inhibition of passive systemic anaphylaxis.

scientific article published on 3 February 2017

Anti-infective activities of 11 plants species used in traditional medicine in Malaysia

article

Antibacterial Activity of Arbutus pavarii Pamp against Methicillin-Resistant Staphylococcus aureus (MRSA) and UHPLC-MS/MS Profile of the Bioactive Fraction

scientific article published on 11 November 2020

Antibacterial Activity of Ethanolic Extract of Syzygium polyanthum L. (Salam) Leaves against Foodborne Pathogens and Application as Food Sanitizer.

scientific article published on 19 December 2017

Antibacterial and Antispore Activities of Isolated Compounds from Piper cubeba L

scientific article published on 26 August 2019

Antinociceptive activity of Melicope ptelefolia ethanolic extract in experimental animals.

scientific article published on January 2010

Antioxidant and Xanthine Oxidase Inhibitory Activities ofPersicaria hydropiper

Antioxidant, antityrosinase, anticholinesterase, and nitric oxide inhibition activities of three malaysian macaranga species

article

Antioxidant, radical-scavenging, anti-inflammatory, cytotoxic and antibacterial activities of methanolic extracts of some Hedyotis species.

scientific article published on 27 January 2005

BDMC33, A curcumin derivative suppresses inflammatory responses in macrophage-like cellular system: role of inhibition in NF-κB and MAPK signaling pathways

scientific article

Barrier protective effects of 2,4,6-trihydroxy-3-geranyl acetophenone on lipopolysaccharides-stimulated inflammatory responses in human umbilical vein endothelial cells.

scientific article published on 9 July 2016

Bidesmosidic Oleanane Saponins fromXerospermum noronhianum

article published in 2009

Bioactive Constituents of Zanthoxylum rhetsa Bark and Its Cytotoxic Potential against B16-F10 Melanoma Cancer and Normal Human Dermal Fibroblast (HDF) Cell Lines. ⬇️

scientific article published on 24 May 2016

Bioassay-guided identification of an anti-inflammatory prenylated acylphloroglucinol from Melicope ptelefolia and molecular insights into its interaction with 5-lipoxygenase ⬇️

scientific article published on 10 September 2011

Biological evaluation of curcumin and related diarylheptanoids.

scientific article published on September 2006

Blockade of Eosinophil-Induced Bronchial Epithelial-Mesenchymal Transition with a Geranyl Acetophenone in a Coculture Model

scientific article published on 16 November 2017

Cardamonin, inhibits pro-inflammatory mediators in activated RAW 264.7 cells and whole blood

scientific article published on 5 April 2006

Characterization of Apigenin and Luteolin Derivatives from Oil Palm (Elaeis guineensis Jacq.) Leaf Using LC–ESI-MS/MS

scientific article published on 01 November 2012

Characterization of Metabolite Profile in Phyllanthus niruri and Correlation with Bioactivity Elucidated by Nuclear Magnetic Resonance Based Metabolomics.

scientific article

Characterization of the components present in the active fractions of health gingers (Curcuma xanthorrhiza and Zingiber zerumbet) by HPLC–DAD–ESIMS

article

Chemical characterization and antioxidant activity of three medicinal Apiaceae species

scholarly article in Industrial Crops and Products, vol. 55, April 2014

Chemical constituents and biological activities of Callicarpa maingayi leaves

scientific article published in 2016

Chemical constituents from the stem bark of Clausena excavata Burm. f

scholarly article

Chemical constituents of Melicope ptelefolia

scientific article published on 01 March 2011

Chemical profile and antiacetylcholinesterase, antityrosinase, antioxidant and α-glucosidase inhibitory activity of Cynometra cauliflora L. leaves

scientific article published on 13 August 2014

Chemopreventive effects of a curcumin-like diarylpentanoid [2,6-bis(2,5-dimethoxybenzylidene)cyclohexanone] in cellular targets of rheumatoid arthritis in vitro.

scientific article published on 16 May 2014

Chrotacumines E and F, two new chromone-alkaloid analogs from Dysoxylum acutangulum (Meliaceae) leaves

scientific article published on 01 September 2013

Classification of Raw Stingless Bee Honeys by Bee Species Origins Using the NMR- and LC-MS-Based Metabolomics Approach

scientific article published on 28 August 2018

Classification of Raw Stingless Bee Honeys by Bee Species Origins using NMR-LCMS-based Metabolomics Approach

Comparison of Partial Least Squares and Artificial Neural Network for the prediction of antioxidant activity in extract of Pegaga (Centella) varieties from 1H Nuclear Magnetic Resonance spectroscopy

scholarly article by Maulidiani et al published November 2013 in Food Research International

Complementary Analytical Platforms of NMR Spectroscopy and LCMS Analysis in the Metabolite Profiling of Isochrysis galbana

scientific article published in 2021

Comprehensive GCMS and LC-MS/MS Metabolite Profiling of Chlorella vulgaris

scientific article published on 17 July 2020

Curcumin-like diarylpentanoid analogues as melanogenesis inhibitors.

scientific article

Cytotoxic Properties and Complete Nuclear Magnetic Resonance Assignment of Isolated Xanthones from the Root of Garcinia cowa Roxb.

scientific article

Cytotoxic aaptamines from Malaysian Aaptos aaptos.

scientific article published on 28 December 2008

Cytotoxic caged-polyprenylated xanthonoids and a xanthone from Garcinia cantleyana

scientific article

Cytotoxic xanthones from Garcinia penangiana Pierre

scientific article

Derivatives of pheophorbide-a and pheophorbide-b from photocytotoxic Piper penangense extract.

scientific article

Discrimination and Nitric Oxide Inhibitory Activity Correlation of Ajwa Dates from Different Grades and Origin.

scientific article published on 28 October 2016

Discrimination of Three Pegaga (Centella) Varieties and Determination of Growth-Lighting Effects on Metabolites Content Based on the Chemometry of 1H Nuclear Magnetic Resonance Spectroscopy

scientific article published on 22 December 2011

Discriminative Analysis of Different Grades of Gaharu (Aquilaria malaccensis Lamk.) via ¹H-NMR-Based Metabolomics Using PLS-DA and Random Forests Classification Models. ⬇️

scientific article

Effect of storage time on metabolite profile and alpha-glucosidase inhibitory activity of Cosmos caudatus leaves - GCMS based metabolomics approach

scientific article published on 28 March 2015

Effects of Payena dasyphylla (Miq.) on hyaluronidase enzyme activity and metalloproteinases protein expressions in interleukin-1β stimulated human chondrocytes cells

scientific article

Effects of leaf extract on lipopolysaccharide -induced neuroinflammation in rats: A behavioral and H NMR-based metabolomics study

Erratum to: Zebrafish phenotypic screen identifies novel Notch antagonists.

scientific article published in April 2017

Evaluation of cellular antioxidant activity and chemical constituents of Melicope latifolia (DC.) T. G. Hartley

scholarly article

GC-MS-based metabolite profiling of Cosmos caudatus leaves possessing alpha-glucosidase inhibitory activity

scientific article

Halophenol Rearrangement in Lewis Acid-Catalyzed Friedel - Crafts Conditions: Evidence of Competitive Initial Protonation and Acylation

article

Hematological, Biochemical, Histopathological and ¹H-NMR Metabolomics Application in Acute Toxicity Evaluation of Water Leaf Extract

article

Hits-to-Lead Optimization of the Natural Compound 2,4,6-Trihydroxy-3-geranyl-acetophenone (tHGA) as a Potent LOX Inhibitor: Synthesis, Structure-Activity Relationship (SAR) Study, and Computational Assignment

scientific article

Identification of Dipeptidyl Peptidase-4 and α-Amylase Inhibitors from <i>Melicope glabra</i> (Blume) T. G. Hartley (Rutaceae) Using Liquid Chromatography Tandem Mass Spectrometry, In Vitro and In Silico Methods

scientific article published on 22 December 2020

Identification of nitric oxide inhibitory compounds from the rhizome of Curcuma xanthorrhiza

scholarly article

Identification of the compositional changes in Orthosiphon stamineus leaves triggered by different drying techniques using 1 H NMR metabolomics

scientific article

Identification of α-glucosidase inhibitors from Clinacanthus nutans leaf extract using liquid chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking

scientific article published on 15 November 2018

Identification of α-glucosidase inhibitory compounds from <i>Curcuma mangga</i> fractions ⬇️

scholarly article

In Vitro Wound Healing Potential of Flavonoid C-Glycosides from Oil Palm (Elaeis guineensis Jacq.) Leaves on 3T3 Fibroblast Cells

scientific article published on 17 April 2020

In silico studies, nitric oxide, and cholinesterases inhibition activities of pyrazole and pyrazoline analogs of diarylpentanoids

scientific article published on 04 September 2020

Influence of Different Drying Treatments and Extraction Solvents on the Metabolite Profile and Nitric Oxide Inhibitory Activity of Ajwa Dates

scientific article

Infrared-metabolomics approach in detecting changes inAndrographis paniculatametabolites due to different harvesting ages and times

scientific article published on 24 November 2014

Inhibition of UVB-induced pro-inflammatory cytokines and MMP expression by Zanthoxylum rhetsa bark extract and its active constituent hesperidin

scientific article published on 19 April 2018

LAT is essential for the mast cell stabilising effect of tHGA in IgE-mediated mast cell activation

scientific article published on 13 August 2017

LC–DAD–ESI-MS analysis of nitric oxide inhibitory fractions of tenggek burung (Melicope ptelefolia Champ. ex Benth.)

LC–DAD–ESIMS/MS characterization of antioxidant and anticholinesterase constituents present in the active fraction from Persicaria hydropiper

Mapping Molecular Networks within Clitoria ternatea Linn. against LPS-Induced Neuroinflammation in Microglial Cells, with Molecular Docking and In Vivo Toxicity Assessment in Zebrafish

scientific article published in 2022

Mass Spectrometry-Based Metabolomics Combined with Quantitative Analysis of the Microalgal Diatom (Chaetoceros calcitrans)

scientific article published on 30 July 2020

Mast cell stabilizing effect of a geranyl acetophenone in dengue virus infection using in vitro model of DENV3-induced RBL-2H3 cells.

scientific article

Mechanisms Underlying the Anti-Inflammatory Effects of Clinacanthus nutans Lindau Extracts: Inhibition of Cytokine Production and Toll-Like Receptor-4 Activation

scientific article published on 2 February 2016

Metabolic and biochemical changes in streptozotocin induced obese-diabetic rats treated with Phyllanthus niruri extract. ⬇️

scientific article published on 4 June 2016

Metabolite Characterization and Correlations with Antioxidant and Wound Healing Properties of Oil Palm (<i>Elaeis guineensis</i> Jacq.) Leaflets via <sup>1</sup>H-NMR-Based Metabolomics Approach

scientific article published on 30 November 2020

Metabolite Profiling of Christia vespertilionis Leaf Metabolome via Molecular Network Approach

scientific article published in 2021

Metabolite Profiling of Different Solvent Extracts of the Microalgae Chlorella vulgaris Via 1H NMR-Based Metabolomics

scientific article published in 2021

Metabolite Profiling of the Microalgal Diatom Chaetoceros Calcitrans and Correlation with Antioxidant and Nitric Oxide Inhibitory Activities via ¹H NMR-Based Metabolomics.

scientific article

Metabolite profiling of Ipomoea aquatica at different growth stages in correlation to the antioxidant and α-glucosidase inhibitory activities elucidated by 1H NMR-based metabolomics

Metabolite profiling of Neptunia oleracea and correlation with antioxidant and α-glucosidase inhibitory activities using 1H NMR-based metabolomics

Metabolomic analysis and biochemical changes in the urine and serum of streptozotocin-induced normal- and obese-diabetic rats

scientific article published on 15 May 2018

Metabolomics-Driven Discovery of an Introduced Species and Two Malaysian Piper betle L. Variants

scientific article published on 19 November 2021

Multi-Platform Metabolomics Analyses Revealed the Complexity of Serum Metabolites in LPS-Induced Neuroinflammed Rats Treated with <i>Clinacanthus nutans</i> Aqueous Extract

scientific article published on 09 June 2021

Naturally occurring labdane diterpene and benzofuran from Globba pendula.

scientific article published in August 2009

Nitric oxide inhibitory activity and antioxidant evaluations of 2-benzoyl-6-benzylidenecyclohexanone analogs, a novel series of curcuminoid and diarylpentanoid derivatives

scientific article published on 30 May 2015

Novel 2-Benzoyl-6-(2,3-Dimethoxybenzylidene)-Cyclohexenol Confers Selectivity toward Human MLH1 Defective Cancer Cells through Synthetic Lethality

scientific article published on 21 March 2019

Pharmacokinetics and Metabolism of Liposome-Encapsulated 2,4,6-Trihydroxygeranylacetophenone in Rats Using High-Resolution Orbitrap Liquid Chromatography Mass Spectrometry

scientific article published on 06 July 2020

Phytochemical Screening and Acute Oral Toxicity Study of Java Tea Leaf Extracts

scientific article published on 27 December 2015

Phytochemical and bioactivity alterations of Curcuma species harvested at different growth stages by NMR-based metabolomics

scholarly article

Phytochemical and biological features of Phyllanthus niruri and Phyllanthus urinaria harvested at different growth stages revealed by 1 H NMR-based metabolomics

scholarly article in Industrial Crops and Products, vol. 77, December 2015

Phytochemical diversity of Clinacanthus nutans extracts and their bioactivity correlations elucidated by NMR based metabolomics

article published in 2015

Phytochemical profiles and biological activities of Curcuma species subjected to different drying methods and solvent systems: NMR-based metabolomics approach

scholarly article in Industrial Crops and Products, vol. 94, December 2016

Plasma and urine metabolite profiling reveals the protective effect of Clinacanthus nutans in an ovalbumin-induced anaphylaxis model: 1 H-NMR metabolomics approach

scientific article published on 22 June 2018

Prioritization of natural extracts by LC-MS-PCA for the identification of new photosensitizers for photodynamic therapy

scientific article published on 13 January 2014

Relationship Between Metabolites Composition and Biological Activities of Phyllanthus niruri Extracts Prepared by Different Drying Methods and Solvents Extraction

article

Stability Study of Algerian Nigella sativa Seeds Stored under Different Conditions.

scientific article published on February 2017

Structural analysis of peptides that interact with Newcastle disease virus

scientific article

Structural characterization and evaluation of prebiotic activity of oil palm kernel cake mannanoligosaccharides

scientific article published on 27 April 2017

Synthesis and biological evaluation of curcumin-like diarylpentanoid analogues for anti-inflammatory, antioxidant and anti-tyrosinase activities.

scientific article published on 26 March 2009

Synthesis and docking studies of 2,4,6-trihydroxy-3-geranylacetophenone analogs as potential lipoxygenase inhibitor

Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents

scientific article published on 9 October 2014

The Protective Effects of a Synthetic Geranyl Acetophenone in a Cellular Model of TNF-α-Induced Pulmonary Epithelial Barrier Dysfunction.

scientific article

The anti-neuroinflammatory effects of Clinacanthus nutans leaf extract on metabolism elucidated through 1H NMR in correlation with cytokines microarray

scientific article published on 14 September 2020

The geranyl acetophenone tHGA attenuates human bronchial smooth muscle proliferation via inhibition of AKT phosphorylation

scientific article published in Scientific Reports

Two New Xanthones from Calophyllum nodusum (Guttiferae) ⬇️

scientific article published on October 25, 2011

Two new naphthoquinone derivatives from the stem bark of Callicarpa maingayi.

scientific article published in October 2012

Urinary metabolic profiling of cisplatin nephrotoxicity and nephroprotective effects of Orthosiphon stamineus leaves elucidated by 1H NMR spectroscopy

scientific article

Urinary metabolomics study on the protective role of Orthosiphon stamineus in Streptozotocin induced diabetes mellitus in rats via 1H NMR spectroscopy

scientific article

Variation in the metabolites and α-glucosidase inhibitory activity of Cosmos caudatus at different growth stages

scientific article published on 05 September 2019

Water extract of Clinacanthus nutans leaves exhibits in vitro, ex vivo and in vivo anti-angiogenic activities in endothelial cell via suppression of cell proliferation.

scientific article published on 6 July 2018

Zebrafish phenotypic screen identifies novel Notch antagonists.

scientific article published on 5 January 2017

cis-Clerodane-type furanoditerpenoids from Tinospora crispa.

scientific article published on April 2010

Paulina is supported by:

About Paulina

Help