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List of works by Stanley L. Hazen

2 H 2 O-Based High-Density Lipoprotein Turnover Method for the Assessment of Dynamic High-Density Lipoprotein Function in Mice ⬇️

scientific article published on June 13, 2013

A CD36-dependent signaling cascade is necessary for macrophage foam cell formation

scientific article published on September 2006

A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors

scientific article published on 01 March 2020

A Novel Cell-Free Fluorescent Assay for HDL Function: Low Apolipoprotein A1 Exchange Rate Associated with Increased Incident Cardiovascular Events

scientific article published on 01 May 2020

A Systematic Investigation of Structure/Function Requirements for the Apolipoprotein A-I/Lecithin Cholesterol Acyltransferase Interaction Loop of High-density Lipoprotein

scientific article published on 21 January 2016

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex

scientific article published on 7 February 2012

A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.

scientific article published on 26 July 2002

A novel folding intermediate state for apolipoprotein A-I: role of the amino and carboxy termini

scientific article

A novel multistep mechanism for oxygen binding to ferrous hemoproteins: rapid kinetic analysis of ferrous-dioxy myeloperoxidase (compound III) formation

scientific article published on 01 September 2004

A simple and sensitive enzymatic method for cholesterol quantification in macrophages and foam cells ⬇️

scientific article published on August 4, 2010

A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species

scientific article published on 27 February 2002

ABCA1 mediates unfolding of apolipoprotein AI N terminus on the cell surface before lipidation and release of nascent high-density lipoprotein

scientific article published on 4 April 2013

ASSOCIATIONS BETWEEN LONG CHAIN CERAMIDE LEVELS AND HEART FAILURE PHENOTYPES IN STABLE CARDIAC PATIENTS

scholarly article published in March 2018

Acute exposure to apolipoprotein A1 inhibits macrophage chemotaxis in vitro and monocyte recruitment in vivo

scientific article published on 30 August 2016

Alterations of the arginine metabolome in asthma

scientific article

Ambient Air Pollution Is Associated With the Severity of Coronary Atherosclerosis and Incident Myocardial Infarction in Patients Undergoing Elective Cardiac Evaluation

scientific article published on 28 July 2016

An LRP8 variant is associated with familial and premature coronary artery disease and myocardial infarction

scientific article

An abundant dysfunctional apolipoprotein A1 in human atheroma

scientific article published on 26 January 2014

An antiatherosclerotic signaling cascade involving intestinal microbiota, microRNA-10b, and ABCA1/ABCG1-mediated reverse cholesterol transport

scientific article

An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype

scientific article

Apolipoprotein A-I anti-tumor activity targets cancer cell metabolism

scientific article published on 12 May 2020

Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease

scientific article published on August 2004

Apolipoprotein A-I tryptophan substitution leads to resistance to myeloperoxidase-mediated loss of function

scientific article published on 07 August 2008

Arsenic induces structural and compositional colonic microbiome change and promotes host nitrogen and amino acid metabolism.

scientific article published on 31 October 2015

Ascorbate decreases Fabry cerebral hyperperfusion suggesting a reactive oxygen species abnormality: an arterial spin tagging study

scientific article published in October 2004

Aspirin hydrolysis in plasma is a variable function of butyrylcholinesterase and platelet-activating factor acetylhydrolase 1b2 (PAFAH1b2)

scientific article published on 18 March 2013

Association between four SNPs on chromosome 9p21 and myocardial infarction is replicated in an Italian population.

scientific article published on 8 December 2007

Association between nitrotyrosine levels and microvascular density in human breast cancer

scientific article published in June 2002

Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis

scientific article published on 23 January 2013

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

scientific article published on 21 March 2019

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

scientific article published on 13 July 2020

Association of a genetic risk score with prevalent and incident myocardial infarction in subjects undergoing coronary angiography

scientific article

Association of major depressive disorder with serum myeloperoxidase and other markers of inflammation: a twin study

scientific article published on 02 June 2008

Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy

scientific article published on April 2003

Associations of serum trimethylamine N‐oxide and its precursors with colorectal cancer risk in the Prostate, Lung, Colorectal, Ovarian Cancer Screening Trial Cohort

scholarly article

Atherosclerosis in 2016: Advances in new therapeutic targets for atherosclerosis

scientific article

Atlas of gut microbe-derived products from aromatic amino acids and risk of cardiovascular morbidity and mortality

scientific article published on 21 June 2023

Augmented inducible nitric oxide synthase expression and increased NO production reduce sepsis-induced lung injury and mortality in myeloperoxidase-null mice.

scientific article published on 18 April 2008

Bile acids profile, histopathological indices and genetic variants for non-alcoholic fatty liver disease progression

scientific article published on 01 December 2020

Biomarker-based asthma phenotypes of corticosteroid response

scientific article

Brief Report: Intestinal Microbiota-Produced Trimethylamine-N-Oxide and Its Association With Coronary Stenosis and HIV Serostatus.

scientific article published on 27 January 2016

COVID-19 Is a Coronary Artery Disease Risk Equivalent and Exhibits a Genetic Interaction With ABO Blood Type

scientific article published in 2024

CROTONOBETAINE IS A PROATHEROGENIC GUT MICROBIOTA METABOLITE OF L-CARNITINE

scholarly article

Calcification and Oxidative Modifications Are Associated With Progressive Bioprosthetic Heart Valve Dysfunction

scientific article published on 8 May 2017

Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression

scientific article

Carbamylated Low-Density Lipoprotein and Thrombotic Risk in Chronic Kidney Disease

scientific article published on October 2016

Carbamylation-dependent activation of T cells: a novel mechanism in the pathogenesis of autoimmune arthritis

scientific article

Cardiovascular Biomarkers After Metabolic Surgery Versus Medical Therapy for Diabetes

scientific article published on 01 July 2019

Ceruloplasmin and heart failure in the Atherosclerosis Risk in Communities study

scientific article published on 16 July 2013

Characterization of oxidative pathways in chronic rhinosinusitis and sinonasal polyposis

scientific article published on 01 May 2006

Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure

scientific article published on 23 December 2015

Chronic opioid use modulates human enteric microbiota and intestinal barrier integrity

scientific article published on 01 January 2021

Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration ⬇️

scientific article published on February 22, 2012

Clinical and genetic association of serum ceruloplasmin with cardiovascular risk.

scientific article published on 10 November 2011

Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk

scientific article

Coenzyme Q in asthma

scientific article published on June 2015

Common variants in KCNN3 are associated with lone atrial fibrillation

scientific article

Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of choline and L-carnitine

scientific article

Comparative sensitivities between different plasma B-type natriuretic peptide assays in patients with minimally symptomatic heart failure

scientific article published in January 2005

Comparison of Coronary Atherosclerotic Volume in Patients With Glomerular Filtration Rates ≤60 Versus >60 ml/min/1.73 m2: A Meta-Analysis of Intravascular Ultrasound Studies

article

Concurrent evaluation of novel cardiac biomarkers in acute coronary syndrome: myeloperoxidase and soluble CD40 ligand and the risk of recurrent ischaemic events in TACTICS-TIMI 18.

scientific article

Conformation of an endogenous ligand in a membrane bilayer for the macrophage scavenger receptor CD36

scientific article published on 04 April 2007

Contribution of Gut Bacteria to Lipid Levels: Another Metabolic Role for Microbes?

scientific article published on October 2015

Coordinated series of studies to evaluate characteristics and mechanisms of acute coronary syndromes in high-risk patients randomly assigned to enoxaparin or unfractionated heparin: design and rationale of the SYNERGY Library

scientific article

Coronary Artery Calcification and Changes in Atheroma Burden in Response to Established Medical Therapies

article

Correction: Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains

scientific article published on 2 March 2016

Correlation of High-Density Lipoprotein-Associated Paraoxonase 1 Activity With Systemic Inflammation, Disease Activity, and Cardiovascular Risk Factors in Psoriatic Disease

scientific article published on 8 July 2018

Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma

scientific article published on 05 May 2005

Cystatin C Identifies Patients With Stable Chronic Heart Failure at Increased Risk for Adverse Cardiovascular Events ⬇️

scientific article published on August 16, 2012

Cytokeratin 18 fragment levels as a noninvasive biomarker for nonalcoholic steatohepatitis in bariatric surgery patients

scientific article published on 26 July 2008

Decreased neointimal formation in Nox2-deficient mice reveals a direct role for NADPH oxidase in the response to arterial injury.

scholarly article

Defects in leukocyte-mediated initiation of lipid peroxidation in plasma as studied in myeloperoxidase-deficient subjects: systematic identification of multiple endogenous diffusible substrates for myeloperoxidase in plasma

scientific article published in March 2002

Detectable subclinical myocardial necrosis is associated with cardiovascular risk in stable patients with diabetes.

scientific article published on 7 February 2013

Detrimental Effects of Environmental Tobacco Smoke in Relation to Asthma Severity ⬇️

scientific article published on May 4, 2011

Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential

Dietary metabolism, the gut microbiome, and heart failure

scientific article published on 01 March 2019

Diets high in resistant starch increase plasma levels of trimethylamine-N-oxide, a gut microbiome metabolite associated with CVD risk

scientific article published on 20 December 2016

Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure

scientific article published on 06 August 2008

Diminished Antioxidant Activity of High-Density Lipoprotein–Associated Proteins in Systolic Heart Failure ⬇️

scientific article published on November 9, 2010

Diminished antioxidant activity of high-density lipoprotein-associated proteins in chronic kidney disease

scientific article published on 4 April 2013

Diminished global arginine bioavailability as a metabolic defect in chronic systolic heart failure

scientific article published in February 2013

Double Superhelix Model of High Density Lipoprotein

scientific article

Dual role of the leukocyte integrin αMβ2 in angiogenesis

scientific article published on 26 September 2014

Effect of Vegan Fecal Microbiota Transplantation on Carnitine- and Choline-Derived Trimethylamine-N-Oxide Production and Vascular Inflammation in Patients With Metabolic Syndrome.

scientific article

Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study

scientific article published on 25 April 2007

Effects of Lifestyle Intervention on Plasma Trimethylamine N-Oxide in Obese Adults

scientific article published on 16 January 2019

Effects of Obesity on Lipid-Lowering, Anti-Inflammatory, and Antiatherosclerotic Benefits of Atorvastatin or Pravastatin in Patients With Coronary Artery Disease (from the REVERSAL Study)

scientific article published on 06 April 2006

Effects of Smoking and Smoking Cessation on the Intestinal Microbiota

scientific article published on 14 September 2020

Effects of native and myeloperoxidase-modified apolipoprotein a-I on reverse cholesterol transport and atherosclerosis in mice

scientific article published on 09 January 2014

Effects of the antioxidant succinobucol (AGI-1067) on human atherosclerosis in a randomized clinical trial

scientific article published on 09 January 2007

Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies

scientific article published on 14 October 2011

Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis

scientific article published on 8 June 2018

Emerging role of myeloperoxidase and oxidant stress markers in cardiovascular risk assessment

scientific article

Eosinophil Peroxidase Catalyzed Protein Carbamylation Participates in Asthma

scientific article published on September 2016

Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction

scientific article

Expression of inducible nitric-oxide synthase and intracellular protein tyrosine nitration in vascular smooth muscle cells: role of reactive oxygen species

scientific article published on 10 April 2003

FAMILIAL CHYLOMICRONEMIA SYNDROME: AN INSIGHT INTO ITS CLINICAL CHARACTERISTICS AND LONG TERM CARDIOVASCULAR OUTCOMES

scholarly article published in March 2018

Favorable Impact on LDL Particle Size in Response to Treatment With Pioglitazone is Associated With Less Progression of Coronary Atherosclerosis in Patients With Type 2 Diabetes.

scientific article published in July 2015

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

scientific article published on 22 May 2017

First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation

scientific article published on 16 January 2020

Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis

scientific article

Formation of dysfunctional high-density lipoprotein by myeloperoxidase.

scientific article

Function and distribution of apolipoprotein A1 in the artery wall are markedly distinct from those in plasma

scientific article published on 22 August 2013

Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains

scientific article (publication date: December 2015)

Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report

scientific article published on 01 June 2019

Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease

scientific article published on 01 May 2019

Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus

scientific article published on 13 August 2020

Genetic contribution of the leukotriene pathway to coronary artery disease

scientific article

Genome-wide and gene-centric analyses of circulating myeloperoxidase levels in the charge and care consortia

scientific article published on 24 April 2013

Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease

scientific article published on 29 January 2016

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project

scientific article

Gut Microbe-Generated Trimethylamine N-Oxide From Dietary Choline Is Prothrombotic in Subjects.

scientific article

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

scientific article

Gut Microbiota and Cardiovascular Disease

scientific article published on 30 July 2020

Gut Microbiota in Cardiovascular Health and Disease

scientific article

Gut Microbiota-Dependent Trimethylamine -Oxide Predicts Risk of Cardiovascular Events in Patients With Stroke and Is Related to Proinflammatory Monocytes

scientific article published on 01 September 2018

Gut Microbiota-Dependent Trimethylamine N-oxide and Cardiovascular Outcomes in Patients With Prior Myocardial Infarction: A Nested Case Control Study From the PEGASUS-TIMI 54 Trial

scientific article published on 05 May 2020

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

scientific article

Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms

scientific article published in 2022

Gut microbiota-dependent trimethylamine N-oxide (TMAO) pathway contributes to both development of renal insufficiency and mortality risk in chronic kidney disease

scientific article

Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors

scientific article published on 11 January 2017

HDL from apoA1 transgenic mice expressing the 4WF isoform is resistant to oxidative loss of function

scientific article

Haptoglobin genotype determines myocardial infarct size in diabetic mice

scientific article published on 13 December 2006

Heparin-associated anti-Xa activity and platelet-derived prothrombotic and proinflammatory biomarkers in moderate to high-risk patients with acute coronary syndrome ⬇️

scientific article published on February 1, 2011

High Betaine, a Trimethylamine N-Oxide Related Metabolite, Is Prospectively Associated with Low Future Risk of Type 2 Diabetes Mellitus in the PREVEND Study

scientific article published on 01 November 2019

High-density lipoprotein and atherosclerosis regression: evidence from preclinical and clinical studies

scientific article published on January 2014

High-density lipoprotein function, dysfunction, and reverse cholesterol transport

scientific article published on December 2012

High-density lipoprotein-associated paraoxonase-1 activity for prediction of adverse outcomes in outpatients with chronic heart failure

scientific article published on 7 February 2017

Hyperammonemia-mediated autophagy in skeletal muscle contributes to sarcopenia of cirrhosis.

scientific article

INTEGRATION OF CANCER STEM CELL MAINTENANCE AND LIPID METABOLISM BY SCAVENGER RECEPTORS.

scientific article published in July 2014

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

scientific article

Identification of Critical Paraoxonase 1 Residues Involved in High Density Lipoprotein Interaction

scientific article

Identification of a novel family of oxidized phospholipids that serve as ligands for the macrophage scavenger receptor CD36

scientific journal article

Identification of immunoglobulins that recognize 3-nitrotyrosine in patients with acute lung injury after major trauma

scientific article published on 5 October 2006

Immunoglobulins Against Tyrosine-Nitrated Epitopes in Coronary Artery Disease ⬇️

scientific article published on October 18, 2012

Impact of Individual Traits, Saturated Fat, and Protein Source on the Gut Microbiome

scientific article published in 2018

Impact of L-carnitine on plasma lipoprotein(a) concentrations: A systematic review and meta-analysis of randomized controlled trials

scientific article

Impact of chronic dietary red meat, white meat, or non-meat protein on trimethylamine N-oxide metabolism and renal excretion in healthy men and women

scientific article published on 01 February 2019

Improved Prediction of Cardiovascular Disease Based on a Panel of Single Nucleotide Polymorphisms Identified Through Genome-Wide Association Studies ⬇️

scientific article published on August 21, 2010

Increased Trimethylamine N-Oxide Portends High Mortality Risk Independent of Glycemic Control in Patients with Type 2 Diabetes Mellitus

scientific article published on 18 November 2016

Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension

scientific article published on 13 September 2004

Increased protein nitration burden in the atherosclerotic lesions and plasma of apolipoprotein A-I deficient mice

scientific article published on 05 July 2007

Indole-3-Propionic Acid Protects Against Heart Failure With Preserved Ejection Fraction

scholarly article

Inflammatory and oxidative markers in atherosclerosis: relationship to outcome

scientific article published on May 2004

Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.

scientific article

Intestinal Microbiota in Cardiovascular Health and Disease: JACC State-of-the-Art Review

scientific article published on 01 April 2019

Intestinal Microbiota-Generated Metabolite Trimethylamine-N-Oxide and 5-Year Mortality Risk in Stable Coronary Artery Disease: The Contributory Role of Intestinal Microbiota in a COURAGE-Like Patient Cohort

scientific article published on 10 June 2016

Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk

scientific article

Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

scientific article

Intestinal microbiota-dependent phosphatidylcholine metabolites, diastolic dysfunction, and adverse clinical outcomes in chronic systolic heart failure

scientific article

Investigation of 95 variants identified in a genome-wide study for association with mortality after acute coronary syndrome

scientific article

Isolevuglandins, a novel class of isoprostenoid derivatives, function as integrated sensors of oxidant stress and are generated by myeloperoxidase in vivo.

scientific article

Kindlin-2 regulates hemostasis by controlling endothelial cell-surface expression of ADP/AMP catabolic enzymes via a clathrin-dependent mechanism

scientific article published on 29 July 2013

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Latency and substrate binding globally reduce solvent accessibility of plasminogen activator inhibitor type 1 (PAI-1). An adaptation of PAI-1 conformer crystal structures by hydrogen-deuterium exchange

scientific article published on 26 August 2004

Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions.

scientific article published on 13 December 2005

Localization of nitration and chlorination sites on apolipoprotein A-I catalyzed by myeloperoxidase in human atheroma and associated oxidative impairment in ABCA1-dependent cholesterol efflux from macrophages

scientific article published on 21 October 2004

Loss of HDAC6 alters gut microbiota and worsens obesity

scientific article published on 13 August 2018

Mass spectrometric profiling of oxidized lipid products in human nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

scientific article

Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry

scientific article published in April 2014

Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction

scientific article published on 29 October 2007

Metabolism of 3-nitrotyrosine induces apoptotic death in dopaminergic cells.

scientific article published on June 2006

Metaorganismal nutrient metabolism as a basis of cardiovascular disease

scientific article

Microbe-derived uremic solutes enhance thrombosis potential in the host

scientific article published on 19 December 2023

Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential

scientific article published on 01 October 2018

Microbial modulation of cardiovascular disease

scientific article published on 8 January 2018

Microbiome, trimethylamine N-oxide, and cardiometabolic disease

scientific article

Modification of high density lipoprotein by myeloperoxidase generates a pro-inflammatory particle

scientific article published on 02 September 2009

Modulation of the gut microbiota impacts nonalcoholic fatty liver disease: a potential role for bile acids

scientific article published on 22 May 2017

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases

scientific article

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases

Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer

scientific article published on 27 June 2017

Myeloperoxidase Mediates Postischemic Arrhythmogenic Ventricular Remodeling

scientific article published on 12 April 2017

Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation

scientific article

Myeloperoxidase aggravates pulmonary arterial hypertension by activation of vascular Rho-kinase.

scientific article

Myeloperoxidase and cardiovascular disease.

scientific article

Myeloperoxidase and plasminogen activator inhibitor 1 play a central role in ventricular remodeling after myocardial infarction

scientific article

Myeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation

scientific article published on 12 March 2004

Myeloperoxidase functions as a major enzymatic catalyst for initiation of lipid peroxidation at sites of inflammation

scientific article published on 30 September 2002

Myeloperoxidase levels predict accelerated progression of coronary atherosclerosis in diabetic patients: insights from intravascular ultrasound

scientific article

Myeloperoxidase metabolizes thiocyanate in a reaction driven by nitric oxide

scientific article published on 01 January 2006

Myeloperoxidase, modified lipoproteins, and atherogenesis

scientific article published on 16 December 2008

Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex

scientific article published on August 2013

Myeloperoxidase-derived 2-chlorofatty acids contribute to human sepsis mortality via acute respiratory distress syndrome

scientific article published on 7 December 2017

Myeloperoxidase-generated oxidants modulate left ventricular remodeling but not infarct size after myocardial infarction

scientific article published on November 2005

Myeloperoxidase-mediated protein lysine oxidation generates 2-aminoadipic acid and lysine nitrile in vivo

scientific article published on 6 January 2017

NMR quantification of trimethylamine-N-oxide in human serum and plasma in the clinical laboratory setting

scientific article published on 14 June 2017

New gene functions in megakaryopoiesis and platelet formation

scientific article published on 30 November 2011

Nitrated fibrinogen is a biomarker of oxidative stress in venous thromboembolism

scientific article

Nitric oxide bioavailability and adiponectin production in chronic systolic heart failure: relation to severity of cardiac dysfunction

scientific article published on 13 March 2013

Nitrotyrosine proteome survey in asthma identifies oxidative mechanism of catalase inactivation

scientific article published in May 2006

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

Non-Linear Relationship between Anti-Apolipoprotein A-1 IgGs and Cardiovascular Outcomes in Patients with Acute Coronary Syndromes

scientific article published on 09 July 2019

Noninvasive markers of airway inflammation in asthma

scientific article

Nonlethal Inhibition of Gut Microbial Trimethylamine N-oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure

scientific article published on 10 May 2020

Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production

scientific article published on 14 January 2022

OxNASH score correlates with histologic features and severity of nonalcoholic fatty liver disease

scientific article

Oxidation increases mucin polymer cross-links to stiffen airway mucus gels

scientific article

Oxidative and nitrosative events in asthma

scientific article

Oxidatively Truncated Docosahexaenoate Phospholipids: Total Synthesis, Generation, and Peptide Adduction Chemistry ⬇️

scientific article published on May 16, 2003

Oxidized phosphatidylserine-CD36 interactions play an essential role in macrophage-dependent phagocytosis of apoptotic cells

scientific article

Oxido-reductive regulation of vascular remodeling by receptor tyrosine kinase ROS1.

scientific article

PI(4,5)P2 Is Translocated by ABCA1 to the Cell Surface Where It Mediates Apolipoprotein A1 Binding and Nascent HDL Assembly

scientific article published on 11 August 2016

Paradoxical association of enhanced cholesterol efflux with increased incident cardiovascular risks

scientific article published on 21 March 2013

Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: New evidence on the potential therapeutic mechanism ⬇️

scientific article published on October 1, 2012

Peroxisome proliferator-activated receptor gamma agonists for the Prevention of Adverse events following percutaneous coronary Revascularization--results of the PPAR study

scientific article published in July 2007

Phospholipid hydroxyalkenals, a subset of recently discovered endogenous CD36 ligands, spontaneously generate novel furan-containing phospholipids lacking CD36 binding activity in vivo

scientific article published on 14 August 2006

Pilot candidate gene analysis of patients ≥ 60 years old with aortic stenosis involving a tricuspid aortic valve

scientific article published on 05 April 2012

Plasma Myeloperoxidase Levels Correlate with the Presence of Fibrosis in Patients with Nonalcoholic Fatty Liver Disease ⬇️

scholarly article

Plasma Trimethylamine N-Oxide, a Gut Microbe-Generated Phosphatidylcholine Metabolite, Is Associated With Atherosclerotic Burden

scientific article published on June 2016

Plasma ceruloplasmin, a regulator of nitric oxide activity, and incident cardiovascular risk in patients with CKD.

scientific article published on 05 December 2013

Plasma myeloperoxidase levels in patients with chronic heart failure

scientific article published on 28 July 2006

Plasma myeloperoxidase predicts incident cardiovascular risks in stable patients undergoing medical management for coronary artery disease ⬇️

scientific article published on November 8, 2010

Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype.

scientific article

Polyunsaturated phospholipids promote the oxidation and fragmentation of gamma-hydroxyalkenals: formation and reactions of oxidatively truncated ether phospholipids

scientific article

Porphyrin-Based SOD Mimic MnTnBu OE -2-PyP Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis

scientific article published on 01 October 2018

Predicting long-term prognosis in stable peripheral artery disease with baseline functional capacity estimated by the Duke Activity Status Index

scientific article published on 20 October 2016

Pro-thrombotic state induced by post-translational modification of fibrinogen by reactive nitrogen species.

scientific article published on 17 December 2003

Probiotic therapy to attenuate weight gain and trimethylamine-N-Oxide generation: A cautionary tale

scientific article

Prognostic Value of Gut Microbe‐Generated Metabolite Phenylacetylglutamine in Patients with Heart Failure

scientific article published on 20 December 2023

Prognostic comparison of different sensitivity cardiac troponin assays in stable heart failure

scientific article

Prognostic value and echocardiographic determinants of plasma myeloperoxidase levels in chronic heart failure

scientific article published on 4 June 2007

Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide

scientific article

Prognostic value of elevated levels of intestinal microbe-generated metabolite trimethylamine-N-oxide in patients with heart failure: refining the gut hypothesis

scientific article

Prognostic value of estimated functional capacity incremental to cardiac biomarkers in stable cardiac patients

scientific article

Prognostic value of myeloperoxidase in patients with chest pain

scientific article

Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism

scientific article published on 01 February 2022

Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylation

scientific article published on 5 July 2012

Protective role of macrophage-derived ceruloplasmin in inflammatory bowel disease.

scientific article published on 16 February 2012

Protein Backbone and Average Particle Dynamics in Reconstituted Discoidal and Spherical HDL Probed by Hydrogen Deuterium Exchange and Elastic Incoherent Neutron Scattering

scientific article published on 10 January 2020

Protein carbamylation and cardiovascular disease

scientific article

Protein carbamylation in chronic systolic heart failure: relationship with renal impairment and adverse long-term outcomes

scientific article

Protein carbamylation links inflammation, smoking, uremia and atherogenesis.

scientific article

Protein carbamylation predicts mortality in ESRD.

scientific article published on 21 February 2013

Pulmonary and systemic nitric oxide metabolites in a baboon model of neonatal chronic lung disease

scientific article published on 15 September 2005

Pulmonary hypertension associated with advanced systolic heart failure: dysregulated arginine metabolism and importance of compensatory dimethylarginine dimethylaminohydrolase-1.

scientific article published on March 2012

Pulmonary vascular disease in mice xenografted with human BM progenitors from patients with pulmonary arterial hypertension ⬇️

scientific article published on June 28, 2012

Quantification of 3-nitrotyrosine levels using a benchtop ion trap mass spectrometry method

scientific article

Quantification of bile acids: a mass spectrometry platform for studying gut microbe connection to metabolic diseases

scientific article published on 09 December 2019

Quantification of fatty acid oxidation products using online high-performance liquid chromatography tandem mass spectrometry

scientific article published on 14 March 2013

RELATIONSHIP BETWEEN STATIN USE AND TRIMETHYLAMINE N-OXIDE IN CARDIOVASCULAR RISK ASSESSMENT

scholarly article published in March 2018

Rapid and selective oxygen-regulated protein tyrosine denitration and nitration in mitochondria

scientific article published on 14 April 2004

Rate of Progression of Coronary Atherosclerotic Plaque in Women

scientific article published on 26 March 2007

Reduced Cardiovascular Risk Following Bariatric Surgeries is Related to a Partial Recovery from “Adiposopathy” ⬇️

scientific article published on December 1, 2011

Relation of Red Cell Distribution Width to Left Ventricular End-Diastolic Pressure and Mortality in Patients With and Without Heart Failure

scientific article published on 10 February 2017

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

scientific article published on 26 May 2017

Relationship Between Cardiovascular Risk Factors and Atherosclerotic Disease Burden Measured by Intravascular Ultrasound

scientific article published on 24 April 2006

Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk

scientific article

Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort

scientific article

Reply: Trimethylamine N-Oxide in Seafood: Rotten or Forgotten?

scientific article published on 01 December 2016

Reply: Trimethylamine-N-Oxide and Heart Failure

scientific article published on 01 July 2015

Response to Letter Regarding Article, “Metabolic Profiling of Arginine and Nitric Oxide Pathways Predicts Hemodynamic Abnormalities and Mortality in Patients With Cardiogenic Shock After Acute Myocardial Infarct”

Risk prediction with serial myeloperoxidase monitoring in patients with acute chest pain.

scientific article published on 22 September 2011

Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine

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Saturated fatty acids regulate retinoic acid signalling and suppress tumorigenesis by targeting fatty acid-binding protein 5

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Seeking a unique lipid signature predicting cardiovascular disease risk

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Serum Myeloperoxidase and Mortality in Maintenance Hemodialysis Patients

Serum Trimethylamine N-oxide, Carnitine, Choline, and Betaine in Relation to Colorectal Cancer Risk in the Alpha Tocopherol, Beta Carotene Cancer Prevention Study

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Serum myeloperoxidase levels independently predict endothelial dysfunction in humans.

scientific article published on 23 August 2004

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Siglec receptors impact mammalian lifespan by modulating oxidative stress

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Signal transduction and oxidative processes in sinonasal polyposis

scientific article published in November 2007

Site-specific 5-hydroxy-tryptophan incorporation into apolipoprotein A-I impairs cholesterol efflux activity and high density lipoprotein biogenesis

scientific article published on 25 February 2020

Site-specific nitration of apolipoprotein A-I at tyrosine 166 is both abundant within human atherosclerotic plaque and dysfunctional

scientific article

Site-specific nitration of apolipoprotein A-I at tyrosine 166 is both abundant within human atherosclerotic plaque and dysfunctional

Small Molecule Inhibition of Gut Microbial Choline Trimethylamine Lyase Activity Alters Host Cholesterol and Bile Acid Metabolism

scientific article published on 24 April 2020

Sphingomyelin depletion impairs anionic phospholipid inward translocation and induces cholesterol efflux

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Stable isotope dilution mass spectrometry quantification of hydrogen sulfide and thiols in biological matrices

scientific article published in 2022

Statins promote potent systemic antioxidant effects through specific inflammatory pathways

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Statins, High-Density Lipoprotein Cholesterol, and Regression of Coronary Atherosclerosis

scientific article published in The Journal of the American Medical Association

Strain dropouts reveal interactions that govern the metabolic output of the gut microbiome

scientific article published in June 2023

Structural control of caspase-generated glutamyl-tRNA synthetase by appended noncatalytic WHEP domains.

scientific article published on 11 April 2018

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

scientific article published on 21 March 2019

Superoxide dismutase inactivation in pathophysiology of asthmatic airway remodeling and reactivity

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Systematic Error Removal Using Random Forest for Normalizing Large-Scale Untargeted Lipidomics Data

scientific article published on 19 February 2019

Systemic elevations of free radical oxidation products of arachidonic acid are associated with angiographic evidence of coronary artery disease

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Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease

scientific article published on 14 May 2015

Target-selective protein S-nitrosylation by sequence motif recognition

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Targeted Inhibition of Gut Microbial TMAO Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease

scientific article published on 26 March 2020

Targeting of microbe-derived metabolites to improve human health: The next frontier for drug discovery

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The Autistic Phenotype Exhibits a Remarkably Localized Modification of Brain Protein by Products of Free Radical-Induced Lipid Oxidation

scientific article published on 02 October 2009

The Gut Microbiome and Its Role in Cardiovascular Diseases.

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The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance

scientific article published on 14 January 2015

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue

scientific article published in June 2017

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue.

scientific article

The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects

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The lipid whisker model of the structure of oxidized cell membranes

scientific article published on 28 November 2007

The low-resolution structure of nHDL reconstituted with DMPC with and without cholesterol reveals a mechanism for particle expansion.

scientific article published on 23 January 2013

The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota L-carnitine catabolism

scientific article published on 23 December 2021

The pattern of apolipoprotein A-I lysine carbamylation reflects its lipidation state and the chemical environment within human atherosclerotic aorta

scientific article published on 15 March 2022

The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction

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The susceptibility of bioprosthetic heart valve leaflets to oxidation

scientific article published on 18 December 2013

The transcription factor GATA-2 does not associate with angiographic coronary artery disease in the Ottawa Heart Genomics and Cleveland Clinic GeneBank Studies

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The utility of biomarkers in diagnosis of aspirin exacerbated respiratory disease

scientific article published on 30 October 2018

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

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Translating Metabolomics to Cardiovascular Biomarkers ⬇️

scientific article published on July 1, 2012

Transmission of atherosclerosis susceptibility with gut microbial transplantation

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Triglyceride levels and not adipokine concentrations are closely related to severity of nonalcoholic fatty liver disease in an obesity surgery cohort

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Trimethylamine N-Oxide Promotes Vascular Inflammation Through Signaling of Mitogen-Activated Protein Kinase and Nuclear Factor-κB.

scientific article published on 22 February 2016

Trimethylamine N-Oxide and Mortality Risk in Patients With Peripheral Artery Disease

scientific article published on 19 October 2016

Trimethylamine N-Oxide levels are associated with NASH in obese subjects with type 2 diabetes

scientific article published on 10 August 2020

Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation ⬇️

scientific article published on January 8, 2013

Trimethyllysine, a trimethylamine N-oxide precursor, provides near- and long-term prognostic value in patients presenting with acute coronary syndromes

scientific article published on 01 August 2019

Two Chromosome 9p21 Haplotype Blocks Distinguish Between Coronary Artery Disease and Myocardial Infarction Risk ⬇️

scientific article published on May 31, 2013

Tyrosine modification is not required for myeloperoxidase-induced loss of apolipoprotein A-I functional activities

scientific article published on 8 August 2005

Tyrosine nitration impairs mammalian aldolase A activity

scientific article

USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease

scientific article published on 02 August 2007

Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.

scientific article

Urinary Bromotyrosine Measures Asthma Control and Predicts Asthma Exacerbations in Children ⬇️

scientific article published on March 10, 2011

Usefulness of Cardiac Biomarker Score for Risk Stratification in Stable Patients Undergoing Elective Cardiac Evaluation Across Glycemic Status ⬇️

scientific article published on December 4, 2012

Usefulness of elevated urine neopterin levels in assessing cardiac dysfunction and exercise ventilation inefficiency in patients with chronic systolic heart failure

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Usefulness of myeloperoxidase levels in healthy elderly subjects to predict risk of developing heart failure

scientific article published on 13 March 2009

Utility of Plasma Concentration of Trimethylamine N-Oxide in Predicting Cardiovascular and Renal Complications in Individuals With Type 1 Diabetes

scientific article published on 23 May 2019

l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans

p53 is a suppressor of inflammatory response in mice.

scientific article published on 5 April 2005

γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO

scientific article

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