List of works - Guillaume Lettre

A common functional PIEZO1 deletion allele associates with red blood cell density in sickle cell disease patients

scientific article published on 09 September 2018

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

scientific article

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Candidate gene association resource (CARe): design, methods, and proof of concept

scientific article

Common variants in the GDF5-UQCC region are associated with variation in human height

scientific article

Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease.

scientific article published on 28 March 2018

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

scientific article

Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium

scientific article

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use

scientific article published on 06 December 2018

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Frameshift indels introduced by genome editing can lead to in-frame exon skipping.

scientific article

Genetic evidence of assortative mating in humans

scholarly article

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations

scientific article

Genome-wide association of anthropometric traits in African- and African-derived populations

scientific article

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project

scientific article

Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection

scientific article

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Identification of ten loci associated with height highlights new biological pathways in human growth

scientific article

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry

scientific article

Integrative analysis of vascular endothelial cell genomic features identifies AIDA as a coronary artery disease candidate gene

scientific article published on 08 July 2019

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

scientific article

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

scientific article

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

scientific article published on 07 January 2019

Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project

scientific article

Multiple loci are associated with white blood cell phenotypes

scientific article

Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome.

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

PHACTR1 splicing isoforms and eQTLs in atherosclerosis-relevant human cells.

scientific article published on 8 June 2018

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

scientific article

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Trans-ethnic meta-analysis of white blood cell phenotypes

scientific article

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

scientific article

List of works by Guillaume Lettre

A common functional PIEZO1 deletion allele associates with red blood cell density in sickle cell disease patients

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

Biological, clinical and population relevance of 95 loci for blood lipids

Candidate gene association resource (CARe): design, methods, and proof of concept

Common variants in the GDF5-UQCC region are associated with variation in human height

Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease.

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis

Defining the role of common variation in the genomic and biological architecture of adult human height

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use

FTO genotype is associated with phenotypic variability of body mass index

Frameshift indels introduced by genome editing can lead to in-frame exon skipping.

Genetic evidence of assortative mating in humans

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations

Genome-wide association of anthropometric traits in African- and African-derived populations

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project

Genome-wide comparison of African-ancestry populations from CARe and other cohorts reveals signals of natural selection

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Identification of ten loci associated with height highlights new biological pathways in human growth

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry

Integrative analysis of vascular endothelial cell genomic features identifies AIDA as a coronary artery disease candidate gene

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project

Multiple loci are associated with white blood cell phenotypes

Neuropilin-1 expression in adipose tissue macrophages protects against obesity and metabolic syndrome.

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

PHACTR1 splicing isoforms and eQTLs in atherosclerosis-relevant human cells.

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Rare and low-frequency coding variants alter human adult height

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Trans-ethnic meta-analysis of white blood cell phenotypes

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis