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List of works by Martin Ingelsson

A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice

scientific article published on 14 January 2008

APOE epsilon 3/ epsilon 4 heterozygotes have an elevated proportion of apolipoprotein E4 in cerebrospinal fluid relative to plasma, independent of Alzheimer's disease diagnosis

scientific article published on 01 September 2003

Abstract 4683: Smoking is associated with mosaic loss of chromosome Y

Abundance of Aβ₅-x like immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer's disease

scientific article published on 02 April 2014

Age-related somatic structural changes in the nuclear genome of human blood cells

scientific article published on 2 February 2012

Aggregated Alpha-Synuclein Transfer Efficiently between Cultured Human Neuron-Like Cells and Localize to Lysosomes

scientific article

Alpha-Synuclein Oligomers-Neurotoxic Molecules in Parkinson's Disease and Other Lewy Body Disorders

scientific article

Alpha-synuclein and chaperones in dementia with Lewy bodies.

scientific article

Alpha-synuclein oligomer-selective antibodies reduce intracellular accumulation and mitochondrial impairment in alpha-synuclein exposed astrocytes

scientific article published on 11 December 2017

Altered levels of CSF proteins in patients with FTD, presymptomatic mutation carriers and non-carriers

scientific article published on 23 June 2020

Alzheimer's disease pathology propagation by exosomes containing toxic amyloid-beta oligomers.

scientific article

Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease

scientific article

Antibodies against alpha-synuclein reduce oligomerization in living cells

scientific article (publication date: 2011)

Association study of cholesterol-related genes in Alzheimer's disease

scientific article published on 27 March 2007

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Aβ and tau prion-like activities decline with longevity in the Alzheimer's disease human brain

scientific article published on 01 May 2019

Aβ38 in the brains of patients with sporadic and familial Alzheimer's disease and transgenic mouse models

scientific article published in January 2014

CALHM1 P86L polymorphism does not alter amyloid-beta or tau in cerebrospinal fluid

scientific article

CRISPR/Cas9 Mediated Disruption of the Swedish APP Allele as a Therapeutic Approach for Early-Onset Alzheimer's Disease.

scientific article

CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimer's disease

scientific article published on 08 September 2016

Cellular Uptake of α-Synuclein Oligomer-Selective Antibodies is Enhanced by the Extracellular Presence of α-Synuclein and Mediated via Fcγ Receptors

scientific article published on 10 March 2016

Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease

scientific article published in December 2014

Clinical and neuropathological features of the arctic APP gene mutation causing early-onset Alzheimer disease

scientific article published on April 2008

Conformationally altered proteins cause neurodegenerative diseases

scientific article published in November 2005

Consensus guidelines for lumbar puncture in patients with neurological diseases

scientific article

Coordinated expression of caspase 8, 3 and 7 mRNA in temporal cortex of Alzheimer disease: relationship to formic acid extractable abeta42 levels

scientific article published in May 2006

Corrigendum to "Low molar excess of 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote oligomerization of alpha-synuclein through different pathways" [Free Rad. Biol. Med. (2017) 421-431].

scientific article

Cystatin C Levels are Positively Correlated with both Aβ42 and Tau Levels in Cerebrospinal Fluid in Persons with Alzheimer's Disease, Mild Cognitive Impairment, and Healthy Controls

scholarly article by Johan Sundelöf et al published 11 August 2010 in Journal of Alzheimer's Disease

Decreased HHV-6 IgG in Alzheimer's Disease

scientific article published on 20 February 2017

Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families

scientific article

Decreased levels of BDNF protein in Alzheimer temporal cortex are independent of BDNF polymorphisms

scientific article published in July 2005

Decreased proportion of cytomegalovirus specific CD8 T-cells but no signs of general immunosenescence in Alzheimer's disease

scientific article

Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer's disease and transgenic mouse models

scientific article published on 8 March 2016

Disordered proteins in dementia

scientific article

Dual-Task Tests Predict Conversion to Dementia-A Prospective Memory-Clinic-Based Cohort Study

scientific article published on 03 November 2020

Dual-task tests discriminate between dementia, mild cognitive impairment, subjective cognitive impairment, and healthy controls - a cross-sectional cohort study

scientific article published on 29 July 2020

Efficient clearance of Aβ protofibrils in AβPP-transgenic mice treated with a brain-penetrating bifunctional antibody.

scientific article

Engulfment adapter PTB domain containing 1 interacts with and affects processing of the amyloid-β precursor protein

scientific article

Expression of APP pathway mRNAs and proteins in Alzheimer's disease

scientific article

Extensive uptake of α-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage

scientific article published on 24 April 2017

Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation.

scientific article published on August 2012

Family-based association between Alzheimer's disease and variants in UBQLN1

scientific article (publication date: 3 March 2005)

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

scientific article published on 08 October 2018

Frontotemporal dementia in a large Swedish family is caused by a progranulin null mutation

scientific article published on 15 October 2008

Gelsolin co-occurs with Lewy bodies in vivo and accelerates α-synuclein aggregation in vitro ⬇️

scientific article published on July 21, 2011

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic predisposition to mosaic Y chromosome loss in blood

scientific article published on 20 November 2019

Genetic predisposition to mosaic Y chromosome loss in blood is associated with genomic instability in other tissues and susceptibility to non-haematological cancers

Genotyping of apolipoprotein E: comparative evaluation of different protocols

scientific article published on 01 November 2003

Heparan sulfate accumulation with Abeta deposits in Alzheimer's disease and Tg2576 mice is contributed by glial cells

scientific article

High tau levels in cerebrospinal fluid predict nursing home placement and rapid progression in Alzheimer's disease

scientific article published on 06 June 2016

Higher Cathepsin B Levels in Plasma in Alzheimer's Disease Compared to Healthy Controls

scholarly article by Johan Sundelöf et al published 7 January 2011 in Journal of Alzheimer's Disease

Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes

scientific article published on 31 October 2017

Human Traumatic Brain Injury Results in Oligodendrocyte Death and Increases the Number of Oligodendrocyte Progenitor Cells

scientific article published on 22 April 2016

Identification of low molecular weight pyroglutamate A{beta} oligomers in Alzheimer disease: a novel tool for therapy and diagnosis

scientific article

Immunotherapy targeting α-synuclein protofibrils reduced pathology in (Thy-1)-h[A30P] α-synuclein mice

scientific article published on 20 May 2014

Immunotherapy targeting α-synuclein, with relevance for future treatment of Parkinson's disease and other Lewy body disorders

scientific article published on January 2014

Improved Differential Diagnosis of Alzheimer's Disease by Integrating ELISA and Mass Spectrometry-Based Cerebrospinal Fluid Biomarkers

In Situ Proximity Ligation Assay Reveals Co-Localization of Alpha-Synuclein and SNARE Proteins in Murine Primary Neurons

scientific article published on 22 March 2018

In vivo multiphoton microscopy of deep tissue with gradient index lenses

Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains

scientific article published on 25 August 2007

Increased Levels of Extracellular Microvesicle Markers and Decreased Levels of Endocytic/Exocytic Proteins in the Alzheimer's Disease Brain

scientific article

Increased Release of Apolipoprotein E in Extracellular Vesicles Following Amyloid-β Protofibril Exposure of Neuroglial Co-Cultures

scientific article published on 17 August 2017

Increased inflammatory response in cytomegalovirus seropositive patients with Alzheimer's disease

scientific article

Increased mRNA Levels of TCF7L2 and MYC of the Wnt Pathway in Tg-ArcSwe Mice and Alzheimer's Disease Brain

scientific article

Intact blood-brain barrier transport of small molecular drugs in animal models of amyloid beta and alpha-synuclein pathology

scientific article published on 5 August 2017

Interference from heterophilic antibodies in amyloid-β oligomer ELISAs

scientific article published on 01 January 2010

Lack of association of the cholesterol 24-hydroxylase (CYP46) intron 2 polymorphism with Alzheimer's disease

scientific article

Large aggregates are the major soluble Aβ species in AD brain fractionated with density gradient ultracentrifugation

scientific article (publication date: 2012)

Low molar excess of 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote oligomerization of alpha-synuclein through different pathways

scientific article

Low prevalence of APP duplications in Swedish and Finnish patients with early-onset Alzheimer's disease

scientific article published on 28 November 2007

Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein

scientific article

Micellar extraction possesses a new advantage for the analysis of Alzheimer's disease brain proteome.

scientific article

Monoclonal antibodies selective for α‐synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and α‐synuclein transgenic mice with the disease‐causing A30P mutation ⬇️

scientific article published on February 27, 2013

Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease

scientific article

Mosaic loss of chromosome Y in leukocytes matters

scientific article published on 01 January 2019

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

Mutagenesis. Smoking is associated with mosaic loss of chromosome Y.

scientific article

N-truncated Abeta starting with position four: early intraneuronal accumulation and rescue of toxicity using NT4X-167, a novel monoclonal antibody

scientific article published on 06 September 2013

Neurofilament ELISA validation

scientific article published on 24 October 2009

No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer's disease brain

scientific article published on 27 June 2006

No association between CALHM1 and Alzheimer's disease risk

scientific article published on December 2008

No evidence of PGRN or MAPT gene dosage alterations in a collection of patients with frontotemporal lobar degeneration

scientific article published on 23 November 2009

Novel progranulin mutation detected in 2 patients with FTLD.

scientific article published on April 2011

Off-pathway α-synuclein oligomers seem to alter α-synuclein turnover in a cell model but lack seeding capability in vivo.

scientific article published on 20 September 2013

PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses

scientific article published in January 2010

Performance and complications of lumbar puncture in memory clinics: Results of the multicenter lumbar puncture feasibility study

scientific article published on 11 September 2015

Plasma beta amyloid and the risk of Alzheimer disease and dementia in elderly men: a prospective, population-based cohort study

scientific article published on February 2008

Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer's disease cases

scientific article published on 13 October 2009

Quantification of the brain proteome in Alzheimer's disease using multiplexed mass spectrometry

scientific article

Quantitative interaction proteomics of neurodegenerative disease proteins

scientific article published on 7 May 2015

Rapid amyloid-β oligomer and protofibril accumulation in traumatic brain injury

scientific article

Rapid progression from mild cognitive impairment to Alzheimer's disease in subjects with elevated levels of tau in cerebrospinal fluid and the APOE epsilon4/epsilon4 genotype

scientific article published on 7 May 2009

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rare mutations aim toward future treatment

scientific article published in May 2009

Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis

scientific article published on 17 September 2013

Reduced plasma desmosterol-to-cholesterol ratio and longitudinal cognitive decline in Alzheimer's disease

scientific article published on 29 March 2015

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Risk factors for subarachnoid haemorrhage: a nationwide cohort of 950 000 adults

scientific article published on 01 December 2019

Self-reported difficulty initiating sleep and early morning awakenings are associated with nocturnal diastolic non-dipping in older white Swedish men

scientific article published on 07 August 2020

Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients

scientific article

Sexually dimorphic effect of the Val66Met polymorphism of BDNF on susceptibility to Alzheimer's disease: New data and meta-analysis

scientific article

Single molecule profiling of tau gene expression in Alzheimer's disease

scientific article published on 28 August 2007

Stability of Proteins in Dried Blood Spot Biobanks

scientific article

Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease

scientific article published on 8 January 2018

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide

scientific article published in 2010

The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ

scientific article

The Arctic amyloid-β precursor protein (AβPP) mutation results in distinct plaques and accumulation of N- and C-truncated Aβ.

scientific article published on 26 November 2011

The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study

scientific article

The amyloid-β degradation pattern in plasma--a possible tool for clinical trials in Alzheimer's disease

scientific article

The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer's disease

scientific article published on 02 August 2020

The lipid peroxidation metabolite 4-oxo-2-nonenal cross-links alpha-synuclein causing rapid formation of stable oligomers

scientific article

The lipid peroxidation products 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote the formation of α-synuclein oligomers with distinct biochemical, morphological, and functional properties ⬇️

scientific article published on February 1, 2011

The normal equilibrium between CSF and plasma amyloid beta levels is disrupted in Alzheimer's disease

scientific article published on 20 September 2007

Transcriptional and conformational changes of the tau molecule in Alzheimer's disease

scientific article

Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer's disease

scientific article published on 31 January 2019

Uniform polarity microtubule assemblies imaged in native brain tissue by second-harmonic generation microscopy

scientific article

[Alzheimer's disease - the most common cause of dementia]

scientific article published on 09 March 2020

α-Synuclein in Extracellular Vesicles: Functional Implications and Diagnostic Opportunities

scientific article published on 18 March 2016

α-Synuclein strains target distinct brain regions and cell types

scientific article published on 02 December 2019

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