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List of works by Gunnar Mellgren

1,25-dihydroxyvitamin D and the vitamin D receptor gene polymorphism Apa1 influence bone mineral density in primary hyperparathyroidism

scientific article

3-Hydroxyisobutyrate, a Strong Marker of Insulin Resistance in Type 2 Diabetes and Obesity That Modulates White and Brown Adipocyte Metabolism

scientific article published on 25 June 2020

A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells

scientific article published on 23 July 2018

A pan-PPAR ligand induces hepatic fatty acid oxidation in PPARalpha-/- mice possibly through PGC-1 mediated PPARdelta coactivation

scientific article published on 3 July 2009

A pooled analysis of CYP2D6 genotype in breast cancer prevention trials of low-dose tamoxifen

scientific article published on 2 August 2016

ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.

scientific article

Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice

scientific article published on 15 March 2019

Activation of cAMP-dependent protein kinase increases the protein level of steroidogenic factor-1

scientific article published on 01 January 2002

Angiopoietin-like protein 8/betatrophin as a new determinant of type 2 diabetes remission after bariatric surgery.

scientific article published on 9 March 2017

Associations between tamoxifen, estrogens, and FSH serum levels during steady state tamoxifen treatment of postmenopausal women with breast cancer

scientific article

Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectoris

scientific article published on 18 December 2014

COL6A3 expression in adipocytes associates with insulin resistance and depends on PPARγ and adipocyte size

scientific article published on 10 April 2014

COL6A3 is regulated by leptin in human adipose tissue and reduced in obesity

scientific article

Changes in adipose glucocorticoid metabolism before and after bariatric surgery assessed by direct hormone measurements

scientific article published on 13 June 2013

Changes in obesity-related diseases and biochemical variables after laparoscopic sleeve gastrectomy: a two-year follow-up study

scientific article

Characterization of receptor-interacting protein RIP140 in the regulation of SF-1 responsive target genes

scientific article

Clinical Characteristics and Long-Term Outcome of Primary Aldosteronism in a Norwegian Population

scientific article published on 18 September 2017

Cyclin C interacts with steroid receptor coactivator 2 and upregulates cell cycle genes in MCF-7 cells

scientific article published on 15 May 2015

Daily Intake of Protein from Cod Residual Material Lowers Serum Concentrations of Nonesterified Fatty Acids in Overweight Healthy Adults: A Randomized Double-Blind Pilot Study.

scientific article published on 5 June 2018

Diets containing salmon fillet delay development of high blood pressure and hyperfusion damage in kidneys in obese Zucker fa/fa rats

scientific article published on 02 February 2018

Differential regulation of SF-1-cofactor interactions

scientific article

Downregulation of steroid receptor coactivator-2 modulates estrogen-responsive genes and stimulates proliferation of mcf-7 breast cancer cells

scientific article

Drug monitoring of tamoxifen metabolites predicts vaginal dryness and verifies a low discontinuation rate from the Norwegian Prescription Database

scientific article published on 29 May 2019

Effect of low-dose tamoxifen on steroid receptor coactivator 3/amplified in breast cancer 1 in normal and malignant human breast tissue.

scientific article published on 23 March 2010

Effects of CYP2D6 and SULT1A1 genotypes including SULT1A1 gene copy number on tamoxifen metabolism

scientific article published on 18 October 2007

Effects of baked and raw salmon fillet on lipids and n-3 PUFAs in serum and tissues in Zucker fa/fa rats.

scientific article

Effects of duodenal switch alone or in combination with sleeve gastrectomy on body weight and lipid metabolism in rats.

scientific article

Effects of low doses of fish and milk proteins on glucose regulation and markers of insulin sensitivity in overweight adults: a randomised, double blind study

scientific article published on 10 April 2019

Efficacy of adrenal venous sampling is increased by point of care cortisol analysis

scientific article

Efficacy of fish intake on vitamin D status: a meta-analysis of randomized controlled trials

scientific article published on 9 September 2015

Efficacy of tamoxifen based on cytochrome P450 2D6, CYP2C19 and SULT1A1 genotype in the Italian Tamoxifen Prevention Trial

scientific article published on 23 March 2010

Elevated plasma dimethylglycine is a risk marker of mortality in patients with coronary heart disease

scientific article published on 26 March 2014

Energy intake, nutritional status and weight reduction in patients one year after laparoscopic sleeve gastrectomy

scientific article published on 30 July 2013

Estradiol determines the effects of PTH on ERα-dependent transcription in MC3T3-E1 cells

scientific article

Excretion of hydroxylated metabolites of tamoxifen in human bile and urine.

scientific article

FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

scientific article

Fish protein hydrolysate elevates plasma bile acids and reduces visceral adipose tissue mass in rats.

scientific article published on 31 January 2009

Five salmon dinners per week were not sufficient to prevent the reduction in serum vitamin D in autumn at 60° north latitude: a randomised trial

scientific article published on 25 November 2019

Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells

scientific article published on 16 March 2010

High intake of fatty fish, but not of lean fish, affects serum concentrations of TAG and HDL-cholesterol in healthy, normal-weight adults: a randomised trial

scientific article

High intake of fatty fish, but not of lean fish, improved postprandial glucose regulation and increased the n-3 PUFA content in the leucocyte membrane in healthy overweight adults: a randomised trial.

scientific article published on 13 June 2017

Hormone references for ultrasound breast staging and endocrine profiling to detect female onset of puberty

scientific article published on 22 September 2020

IRX5 regulates adipocyte amyloid precursor protein and mitochondrial respiration in obesity

scientific article published on 11 December 2018

Identification and quantification of tamoxifen and four metabolites in serum by liquid chromatography-tandem mass spectrometry

scientific article published in July 2005

Induction of hepatic drug-metabolising enzymes and tamoxifen metabolite profile in relation to administration route during low-dose treatment in nude rats

scientific article published on 7 April 2005

Inflammatory markers, the tryptophan-kynurenine pathway, and vitamin B status after bariatric surgery

scientific article

Intake of Baked Cod Fillet Resulted in Lower Serum Cholesterol and Higher Long Chain -3 PUFA Concentrations in Serum and Tissues in Hypercholesterolemic Obese Zucker fa/fa Rats

scientific article published on 28 June 2018

Lack of Ovarian Secretions Reverts the Anabolic Action of Olanzapine in Female Rats

scientific article published on 14 August 2017

Lean Seafood Intake Reduces Postprandial C-peptide and Lactate Concentrations in Healthy Adults in a Randomized Controlled Trial with a Crossover Design

scientific article published on 20 April 2016

Lean-seafood intake decreases urinary markers of mitochondrial lipid and energy metabolism in healthy subjects: Metabolomics results from a randomized crossover intervention study

scientific article

Lean-seafood intake reduces cardiovascular lipid risk factors in healthy subjects: results from a randomized controlled trial with a crossover design

scientific article published on 29 July 2015

Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms

scientific article published on January 2014

Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2).

scientific article

Novel inflammatory biomarkers in primary hyperparathyroidism

scientific article published on 07 April 2015

Nuclear import of glucokinase in pancreatic beta-cells is mediated by a nuclear localization signal and modulated by SUMOylation

scientific article

Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome

scientific article

Predictors for remission of major components of the metabolic syndrome after biliopancreatic diversion with duodenal switch (BPDDS).

scientific article published in January 2013

Primary hyperparathyroidism influences the expression of inflammatory and metabolic genes in adipose tissue

scientific article

Prognostic impact of genetic variants of CYP19A1 and UGT2B17 in a randomized trial for endocrine-responsive postmenopausal breast cancer

scientific article published on 10 April 2019

Prospective Associations of Systemic and Urinary Choline Metabolites with Incident Type 2 Diabetes

scientific article

Recruitment of coactivator glucocorticoid receptor interacting protein 1 to an estrogen receptor transcription complex is regulated by the 3',5'-cyclic adenosine 5'-monophosphate-dependent protein kinase

scientific article

Salmon Fillet Intake Led to Higher Serum Triacylglycerol in Obese Zucker Fa/Fa Rats But Not in Normolipidemic Long-Evans Rats

scientific article published on 08 October 2018

Serum Acylcarnitines and Risk of Cardiovascular Death and Acute Myocardial Infarction in Patients With Stable Angina Pectoris

scientific article published on 03 February 2017

Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients

scientific article published on 28 November 2017

Serum concentrations of tamoxifen and its metabolites increase with age during steady-state treatment

scientific article published on September 2013

Short-term effects of Vertical sleeve gastrectomy and Roux-en-Y gastric bypass on glucose homeostasis

scientific article published on 15 October 2019

Simultaneous assay of cortisol and dexamethasone improved diagnostic accuracy of the dexamethasone suppression test

scientific article

Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer.

scientific article

Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss

scientific article

Synergistic Antiproliferative Actions of Cyclic Adenosine 3′,5′-Monophosphate, Interleukin-1β, and Activators of Ca2+/Calmodulin-Dependent Protein Kinase in Primary Hepatocytes1 ⬇️

scientific article published on October 1, 1997

TMAO, creatine and 1-methylhistidine in serum and urine are potential biomarkers of cod and salmon intake: a randomised clinical trial in adults with overweight or obesity

scientific article published on 10 August 2019

Tamoxifen administration and metabolism in nude mice and nude rats

scientific article published in February 2003

Testicular ultrasound to stratify hormone references in a cross-sectional Norwegian study of male puberty

scientific article published on 26 October 2019

The Effect of Lean-Seafood and Non-Seafood Diets on Fasting and Postprandial Serum Metabolites and Lipid Species: Results from a Randomized Crossover Intervention Study in Healthy Adults.

scientific article published on 11 May 2018

The Effect of Lean-Seafood and Non-Seafood Diets on Fecal Metabolites and Gut Microbiome: Results from a Randomized Crossover Intervention Study

scientific article published on 16 April 2018

The Rho GTPase RND3 regulates adipocyte lipolysis

scientific article published on 28 October 2019

The active tamoxifen metabolite endoxifen (4OHNDtam) strongly down-regulates cytokeratin 6 (CK6) in MCF-7 breast cancer cells

scientific article

The cAMP-dependent protein kinase downregulates glucose-6-phosphatase expression through RORα and SRC-2 coactivator transcriptional activity.

scientific article published on 6 October 2015

The homeobox factor Irx3 maintains adipogenic identity

scientific article published on 18 November 2019

The kynurenine:tryptophan ratio as a predictor of incident type 2 diabetes mellitus in individuals with coronary artery disease

scientific article published on 13 June 2017

The nuclear receptor coactivators p300/CBP/cointegrator-associated protein (p/CIP) and transcription intermediary factor 2 (TIF2) differentially regulate PKA-stimulated transcriptional activity of steroidogenic factor 1

scientific article published on 01 April 2002

The nuclear receptors NUR77, NURR1 and NOR1 in obesity and during fat loss ⬇️

scientific article published on December 6, 2011

The short cosyntropintest revisited - new normal reference range using LCMSMS.

scientific article published on 14 February 2018

Tissue distribution of 4-hydroxy-N-desmethyltamoxifen and tamoxifen-N-oxide

scientific article

Tissue-specific effects of bariatric surgery including mitochondrial function

scientific article

Urine and plasma concentrations of amino acids and plasma vitamin status differ, and are differently affected by salmon intake, in obese Zucker fa/fa rats with impaired kidney function and in Long-Evans rats with healthy kidneys

scientific article published on 09 August 2019

Visceral adiposity and metabolic syndrome after very high-fat and low-fat isocaloric diets: a randomized controlled trial.

scientific article published on 30 November 2016

Vitamin B6 status and interferon-γ-mediated immune activation in primary hyperparathyroidism

scientific article published on 5 August 2012

Weight cycling promotes fat gain and altered clock gene expression in adipose tissue in C57BL/6J mice

scientific article published on 3 December 2013

cAMP response element-binding protein interacts with and stimulates the proteasomal degradation of the nuclear receptor coactivator GRIP1

scientific article published on 5 March 2013

cAMP-dependent protein kinase regulates ubiquitin-proteasome-mediated degradation and subcellular localization of the nuclear receptor coactivator GRIP1.

scientific article published on 3 September 2004

cAMP-mediated regulation of HNF-4alpha depends on the level of coactivator PGC-1alpha

scientific article published on 4 June 2010

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