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Authors whose works are in public domain in at least one jurisdiction

List of works by Fotios Drenos

1-50 of 71 results

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

scientific article published on 14 March 2012

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

scientific article published on 24 September 2014

Mendelian randomization of blood lipids for coronary heart disease

scientific article

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

scientific article

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

scientific article published on 30 January 2017

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

scientific article

Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

scientific article

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

scientific article published on 12 September 2016

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

scientific article

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Blood pressure loci identified with a gene-centric array

scientific article

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

scientific article published on 15 January 2016

Sixty-five common genetic variants and prediction of type 2 diabetes

scientific article published on 4 December 2014

Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration

scientific article published on 30 July 2011

Candidate gene association studies in abdominal aortic aneurysm disease: a review and meta-analysis.

scientific article published on 24 October 2007

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

scientific article published in December 2016

APOE/C1/C4/C2 gene cluster genotypes, haplotypes and lipid levels in prospective coronary heart disease risk among UK healthy men

scientific article

Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

scientific article (publication date: 2013)

Selection on alleles affecting human longevity and late-life disease: the example of apolipoprotein E.

scientific article

Angiotensin-converting enzyme genotype and successful ascent to extreme high altitude

scientific article published on 01 January 2007

Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies

scientific article published on 13 September 2012

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

scientific article published on 30 September 2011

Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5 , shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS study

article

New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals

scientific article published in October 2017

Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip

scientific article published on 28 April 2011

Application of statistical and functional methodologies for the investigation of genetic determinants of coronary heart disease biomarkers: lipoprotein lipase genotype and plasma triglycerides as an exemplar.

scientific article

Clinical Utility of a Coronary Heart Disease Risk Prediction Gene Score in UK Healthy Middle Aged Men and in the Pakistani Population

scientific article published on 2 July 2015

Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis

scientific article published on 28 December 2012

FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy men

scientific article

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

scientific article

Metabolic signatures of birthweight in 18 288 adolescents and adults

scientific article published on October 2016

APOE, CETP and LPL genes show strong association with lipid levels in Greek children

scientific article

The use of Meta-Analysis Risk Estimates for Candidate Genes in Combination to Predict Coronary Heart Disease Risk

article

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

scientific article published on 20 August 2019

Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects

scientific article published on 25 April 2016

A genetic instrument for Mendelian randomization of fibrinogen.

scientific article

Identifying gene-gene interactions that are highly associated with Body Mass Index using Quantitative Multifactor Dimensionality Reduction (QMDR)

scientific article

Marginal role for 53 common genetic variants in cardiovascular disease prediction

scientific article published on 30 June 2016

IRS1 gene variants, dysglycaemic metabolic changes and type-2 diabetes risk.

scientific article published on 14 September 2011

Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.

scientific article published on November 2010

Genetic meta-analysis of 15,901 African Americans identifies variation in EXOC3L1 is associated with HDL concentration.

scientific article

Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip

scientific article published on 8 November 2012

Trade-off mediated effects on the genetics of human survival caused by increasingly benign living conditions

scientific article published on 05 July 2006

A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering

scientific article published on 5 April 2016

Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip

scientific article published on 29 August 2013