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List of works by Asimul Islam

2/3D-QSAR, molecular docking and MD simulation studies of FtsZ protein targeting benzimidazoles derivatives

scientific article published on 27 December 2018

A review of methods available to estimate solvent-accessible surface areas of soluble proteins in the folded and unfolded states

scientific article published on January 2014

A unique molten globule state occurs during unfolding of cytochrome c by LiClO4 near physiological pH and temperature: structural and thermodynamic characterization

scientific article published on 01 April 2006

Atypical PKC phosphorylates microtubule affinity-regulating kinase 4 in vitro.

scientific article published on 7 September 2015

Binding studies and biological evaluation of β-carotene as a potential inhibitor of human calcium/calmodulin-dependent protein kinase IV.

scientific article published on 9 December 2016

Biophysical Elucidation of Fibrillation Inhibition by Sugar Osmolytes in α-Lactalbumin: Multispectroscopic and Molecular Docking Approaches

scientific article published on 08 October 2020

Biophysical analyses of human resistin: oligomer formation suggests novel biological function.

scientific article published in November 2008

Biophysical characterization of G protein ectodomain of group B human respiratory syncytial virus from E. coli.

scientific article published on 7 October 2015

Calcium/calmodulin-dependent protein kinase IV: A multifunctional enzyme and potential therapeutic target.

scientific article

Carbohydrate-Based Macromolecular Crowding-Induced Stabilization of Proteins: Towards Understanding the Significance of the Size of the Crowder

scientific article published on 12 September 2019

Characterisation of molten globule-like state of sheep serum albumin at physiological pH

scientific article published on 11 May 2016

Characterization of folding intermediates during urea-induced denaturation of human carbonic anhydrase II.

scientific article

Characterization of intermediate state of myoglobin in the presence of PEG 10 under physiological conditions.

scientific article published on 24 February 2017

Characterization of pre-molten globule state of yeast iso-1-cytochrome c and its deletants at pH 6.0 and 25 °C

scientific article published on 04 November 2014

Chikungunya virus: recent advances in epidemiology, host pathogen interaction and vaccine strategies.

scientific article

Cloning, expression, purification and characterization of human mitochondrial carbonic anhydrase VA.

scientific article

Cloning, expression, purification and refolding of microtubule affinity-regulating kinase 4 expressed in Escherichia coli.

scientific article published on 21 January 2014

Comparison of the thermal stabilization of proteins by oligosaccharides and monosaccharide mixtures: Measurement and analysis in the context of excluded volume theory.

scientific article published on 22 March 2018

Computing disease-linked SOD1 mutations: deciphering protein stability and patient-phenotype relations

scientific article

Cooperative Unfolding of Residual Structure in Heat Denatured Proteins by Urea and Guanidinium Chloride.

scientific article published on 5 June 2015

Counteraction of the deleterious effects of urea on structure and stability of mammalian kidney proteins by osmolytes.

scientific article published on 10 October 2017

Data on the role of accessible surface area on osmolytes-induced protein stabilization

scientific article (publication date: February 2017)

Delineating the relationship between amyotrophic lateral sclerosis and frontotemporal dementia: Sequence and structure-based predictions

scientific article published on 15 June 2016

Denatured states of yeast cytochrome c induced by heat and guanidinium chloride are structurally and thermodynamically different

Design, synthesis, and biological evaluation of pyrimidine derivatives as potential inhibitors of human calcium/calmodulin-dependent protein kinase IV.

scientific article published on 3 November 2016

Designing New Kinase Inhibitor Derivatives as Therapeutics Against Common Complex Diseases: Structural Basis of Microtubule Affinity-Regulating Kinase 4 (MARK4) Inhibition.

scientific article published on November 2015

Discovery of 4-(2-(dimethylamino)ethoxy)benzohydrazide derivatives as prospective microtubule affinity regulating kinase 4 inhibitors

scientific article published on 27 May 2020

Effect of conservative mutations (L94V and L94I) on the structure and stability of horse cytochrome c.

scientific article

Effect of mammalian kidney osmolytes on the folding pathway of sheep serum albumin.

scientific article published on 21 January 2017

Effect of pH on structure, function, and stability of mitochondrial carbonic anhydrase VA

scientific article published on 04 April 2016

Effect of pH on the stability of hemochromatosis factor E: a combined spectroscopic and molecular dynamics simulation-based study

scientific article

Effect of pH on the structure, function, and stability of human calcium/calmodulin-dependent protein kinase IV: combined spectroscopic and MD simulation studies.

scientific article published on 22 January 2016

Effect of sequential deletion of extra N-terminal residues on the structure and stability of yeast iso-1-cytochrome-c.

scientific article

Ellagic Acid Controls Cell Proliferation and Induces Apoptosis in Breast Cancer Cells via Inhibition of Cyclin-Dependent Kinase 6 ⬇️

scientific article published on 15 May 2020

Elucidating the Interaction of Human Ferritin with Quercetin and Naringenin: Implication of Natural Products in Neurodegenerative Diseases: Molecular Docking and Dynamics Simulation Insight

scientific article published on 11 March 2021

Elucidation of Dietary Polyphenolics as Potential Inhibitor of Microtubule Affinity Regulating Kinase 4: In silico and In vitro Studies.

scientific article published on 25 August 2017

Estimation of pH effect on the structure and stability of kinase domain of human integrin-linked kinase

scientific article published on 21 December 2017

Estimation of thermodynamic stability of human carbonic anhydrase IX from urea-induced denaturation and MD simulation studies.

scientific article published on 5 July 2017

Evaluation of Binding of Rosmarinic Acid with Human Transferrin and Its Impact on the Protein Structure: Targeting Polyphenolic Acid-Induced Protection of Neurodegenerative Disorders

scientific article published on 05 November 2020

Evaluation of human microtubule affinity-regulating kinase 4 inhibitors: fluorescence binding studies, enzyme, and cell assays.

scientific article published on 16 October 2016

Evidence of vanillin binding to CAMKIV explains the anti-cancer mechanism in human hepatic carcinoma and neuroblastoma cells.

scientific article published on 25 July 2017

Exploring Missense Mutations in Tyrosine Kinases Implicated with Neurodegeneration.

scientific article

Exploring molecular insights into the interaction mechanism of cholesterol derivatives with the Mce4A: A combined spectroscopic and molecular dynamic simulation studies

scientific article published on 9 January 2018

First evidence of formation of pre-molten globule state in myoglobin: A macromolecular crowding approach towards protein folding in vivo

scientific article published on 23 December 2018

Folding and stability studies on C-PE and its natural N-terminal truncant

scientific article published on 13 January 2014

Functional annotation of putative hypothetical proteins from Candida dubliniensis.

scientific article

GdmCl-induced unfolding studies of human carbonic anhydrase IX: a combined spectroscopic and MD simulation approach.

scientific article

GdnHCl-induced unfolding intermediate in the mitochondrial carbonic anhydrase VA.

scientific article published on 27 June 2016

Glossary of phytoconstituents: Can these be repurposed against SARS CoV-2? A quick in silico screening of various phytoconstituents from plant Glycyrrhiza glabra with SARS CoV-2 main protease

scientific article published on 14 February 2021

Guanidinium chloride and urea denaturations of beta-lactoglobulin A at pH 2.0 and 25 degrees C: the equilibrium intermediate contains non-native structures (helix, tryptophan and hydrophobic patches)

scientific article published on 25 January 2007

Heterogeneity of equilibrium molten globule state of cytochrome c induced by weak salt denaturants under physiological condition.

scientific article published on 7 April 2015

High throughput screening, docking, and molecular dynamics studies to identify potential inhibitors of human calcium/calmodulin-dependent protein kinase IV

scientific article published on 01 November 2018

Human Disease Insight: An integrated knowledge-based platform for disease-gene-drug information

scientific article published on 26 November 2015

Human microtubule affinity-regulating kinase 4 is stable at extremes of pH.

scientific article published on 21 August 2015

Human β-glucuronidase: structure, function, and application in enzyme replacement therapy.

scientific article published on October 2013

Identification and evaluation of bioactive natural products as potential inhibitors of human microtubule affinity-regulating kinase 4 (MARK4).

scientific article published on 23 April 2018

Identification of Potential Inhibitors of Calcium/Calmodulin-Dependent Protein Kinase IV from Bioactive Phytoconstituents

scientific article published on 16 July 2020

Identification of potential inhibitors of sortase A: Binding studies, in-silico docking and protein-protein interaction studies of sortase A from Enterococcus faecalis

scientific article published on 27 September 2018

Impact of Gln94Glu mutation on the structure and function of protection of telomere 1, a cause of cutaneous familial melanoma

scientific article published on 07 May 2019

In vitro and in silico studies of urea-induced denaturation of yeast iso-1-cytochrome c and its deletants at pH 6.0 and 25 °C

scientific article published on 23 September 2014

Interactions Under Crowding Milieu: Chemical-Induced Denaturation of Myoglobin is Determined by the Extent of Heme Dissociation on Interaction with Crowders

scientific article published on 23 March 2020

Investigating architecture and structure-function relationships in cold shock DNA-binding domain family using structural genomics-based approach

scientific article published on 18 April 2019

Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach

scientific article published on 22 October 2021

Investigation of deleterious effects of nsSNPs in the POT1 gene: a structural genomics-based approach to understand the mechanism of cancer development

scientific article published on 16 December 2018

Investigation of inhibitory potential of quercetin to the pyruvate dehydrogenase kinase 3: Towards implications in anticancer therapy

scientific article published on 22 June 2019

Investigation of molecular mechanism of recognition between citral and MARK4: A newer therapeutic approach to attenuate cancer cell progression

scientific article published on 24 October 2017

Ionic Liquid Green Assembly-Mediated Migration of Piperine from Calf-Thymus DNA: A New Possibility of the Tunable Drug Delivery System

scientific article published on 05 December 2019

MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer's Disease Therapy

scientific article published on 20 May 2020

Macromolecular crowding induces molten globule state in the native myoglobin at physiological pH.

scientific article published on 12 August 2017

Mechanistic insights into the urea-induced denaturation of kinase domain of human integrin linked kinase

scientific article published on 5 January 2018

Microtubule affinity-regulating kinase 4: structure, function, and regulation.

scientific article

Mixture of Macromolecular Crowding Agents Has a Non-additive Effect on the Stability of Proteins

scientific article published on 09 February 2019

Molecular basis of the structural stability of hemochromatosis factor E: A combined molecular dynamic simulation and GdmCl-induced denaturation study

scientific article published on 01 March 2016

Multispectroscopic and Molecular Docking Insight into Elucidating the Interaction of Irisin with Rivastigmine Tartrate: A Combinational Therapy Approach to Fight Alzheimer's Disease

scientific article published on 08 March 2021

New insights into the antioxidant and apoptotic potential of Glycyrrhiza glabra L. during hydrogen peroxide mediated oxidative stress: An in vitro and in silico evaluation.

scientific article

Non-enzymatic glycation enhances human serum albumin binding capacity to sodium fluorescein at room temperature: A spectroscopic analysis.

scientific article published on 12 April 2017

PKR-inhibitor binds efficiently with human microtubule affinity-regulating kinase 4.

scientific article published on 21 October 2015

Probing pH sensitivity of αC-phycoerythrin and its natural truncant: A comparative study.

scientific article

Protein aggregation and neurodegenerative diseases: From theory to therapy.

scientific article

Protein aggregation, misfolding and consequential human neurodegenerative diseases.

scientific article published on 23 January 2017

Protein folding: Molecular dynamics simulations and in vitro studies for probing mechanism of urea- and guanidinium chloride-induced unfolding of horse cytochrome-c

scientific article published on 30 October 2018

Protein stability: Determination of structure and stability of the transmembrane protein Mce4A from M. tuberculosis in membrane-like environment

scientific article published on 23 December 2018

Purification and characterization of RGA2, a Rho2 GTPase-activating protein from Tinospora cordifolia.

scientific article

Purification and characterization of Ras related protein, Rab5a from Tinospora cordifolia.

scientific article published on 27 October 2015

Purification and characterization of calreticulin: a Ca²⁺-binding chaperone from sheep kidney.

scientific article

Purification and characterization of oligonucleotide binding (OB)-fold protein from medicinal plant Tinospora cordifolia.

scientific article

Purification and structural characterization of Mce4A from Mycobacterium tuberculosis.

scientific article published on 26 June 2016

Purification, modeling and structural insights of calmodulin-binding receptor like cytoplasmic kinase 2 from Oroxylum Indicum

scientific article published on 07 November 2018

Purification, preliminary X-ray crystallography and biophysical studies of triose phosphate isomerase-β-globin subunit complex.

scientific article

Refolding of urea denatured cytochrome c: Role of hydrophobic tail of the cationic gemini surfactants

scientific article published on 4 September 2016

Relationship between protein stability and functional activity in the presence of macromolecular crowding agents alone and in mixture: An insight into stability-activity trade-off

scientific article published on 29 August 2015

Role of unique basic residues of human pancreatic ribonuclease in its catalysis and structural stability

scientific article published on 09 July 2007

Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition

scientific article published on 25 June 2020

Sequence, structure and evolutionary analysis of cold shock domain proteins, a member of OB fold family

scientific article published on 19 October 2018

Size-dependent studies of macromolecular crowding on the thermodynamic stability, structure and functional activity of proteins: in vitro and in silico approaches.

scientific article published on 11 November 2016

Spectroscopic and MD simulation studies on unfolding processes of mitochondrial carbonic anhydrase VA induced by urea

scientific article published on 27 January 2016

Spectroscopic, calorimetric and molecular docking insight into the interaction of Alzheimer's drug donepezil with human transferrin: implications of Alzheimer's drug

scientific article published on 02 April 2019

Stability of proteins in the presence of polyols estimated from their guanidinium chloride-induced transition curves at different pH values and 25 degrees C.

scientific article

Structural Analysis and Conformational Dynamics of STN1 Gene Mutations Involved in Coat Plus Syndrome.

scientific article published on 12 June 2019

Structural Features of Nucleoprotein CST/Shelterin Complex Involved in the Telomere Maintenance and Its Association with Disease Mutations

scientific article published on 04 February 2020

Structural and thermodynamic characterisation of L94F mutant of horse cytochrome c.

scientific article published in July 2016

Structural basis of urea-induced unfolding: Unraveling the folding pathway of hemochromatosis factor E.

scientific article published on 20 June 2016

Structural characterization of MG and pre-MG states of proteins by MD simulations, NMR, and other techniques

scientific article

Structural insight into C9orf72 hexanucleotide repeat expansions: Towards new therapeutic targets in FTD-ALS.

scientific article

Structure guided design of potential inhibitors of human calcium-calmodulin dependent protein kinase IV containing pyrimidine scaffold

scientific article published on 30 December 2015

Structure-based functional annotation of hypothetical proteins from Candida dubliniensis: a quest for potential drug targets ⬇️

scientific article published on 17 October 2014

Structure-function studies of Murraya koenigii trypsin inhibitor revealed a stable core beta sheet structure surrounded by alpha-helices with a possible role for alpha-helix in inhibitory function

scientific article published on 05 June 2007

Sugar osmolytes-induced stabilization of RNase A in macromolecular crowded cellular environment.

scientific article published on 14 April 2018

Testing the ability of non-methylamine osmolytes present in kidney cells to counteract the deleterious effects of urea on structure, stability and function of proteins.

scientific article

Testing the dependence of stabilizing effect of osmolytes on the fractional increase in the accessible surface area on thermal and chemical denaturations of proteins

scientific article published on 11 December 2015

The pH Dependence of Saccharides' Influence on Thermal Denaturation of Two Model Proteins Supports an Excluded Volume Model for Stabilization Generalized to Allow for Intramolecular Electrostatic Interactions

scientific article

The role of key residues in structure, function, and stability of cytochrome-c.

scientific article published on 25 April 2013

Therapeutic progress in amyotrophic lateral sclerosis-beginning to learning

scientific article published on 14 June 2016

Thermal Stabilization of Proteins by Mono- and Oligosaccharides: Measurement and Analysis in the Context of an Excluded Volume Model

scientific article published on 03 June 2015

Ubiquitin-associated domain of MARK4 provides stability at physiological pH.

scientific article published on 24 September 2016

Unfoldness of the denatured state of proteins determines urea: Methylamine counteraction in terms of Gibbs free energy of stabilization

scientific article published on 01 April 2019

Unraveling Binding Mechanism of Alzheimer's Drug Rivastigmine Tartrate with Human Transferrin: Molecular Docking and Multi-Spectroscopic Approach towards Neurodegenerative Diseases

scientific article published on 17 September 2019

Unravelling the unfolding mechanism of human integrin linked kinase by GdmCl-induced denaturation.

scientific article

Urea-induced denaturation of human calcium/calmodulin-dependent protein kinase IV: a combined spectroscopic and MD simulation studies.

scientific article published on 2 February 2016

Virtual Screening Approach to Identify High-Affinity Inhibitors of Serum and Glucocorticoid-Regulated Kinase 1 among Bioactive Natural Products: Combined Molecular Docking and Simulation Studies

scientific article published on 13 February 2020

Why is glycine not a part of the osmoticum in the urea-rich cells?

scientific article published in January 2013

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