List of works - Dominique Dardevet

4E-BP1 and 4E-BP2 double knockout mice are protected from aging-associated sarcopenia

scientific article published on 29 March 2019

A dietary supplementation with leucine and antioxidants is capable to accelerate muscle mass recovery after immobilization in adult rats

scientific article

A meal with mixed soy/whey proteins is as efficient as a whey meal in counteracting the age-related muscle anabolic resistance only if the protein content and leucine levels are increased

scientific article published on 01 December 2018

A mix of dietary fermentable fibers improves lipids handling by the liver of overfed minipigs

scientific article published on 08 December 2018

Altered responses in skeletal muscle protein turnover during aging in anabolic and catabolic periods.

scientific article

Arterio-venous metabolomics exploration reveals major changes across liver and intestine in the obese Yucatan minipig

scientific article published on 29 August 2019

Assessment of protein modifications in liver of rats under chronic treatment with paracetamol (acetaminophen) using two complementary mass spectrometry-based metabolomic approaches

scientific article published on 24 March 2015

At same leucine intake, a whey/plant protein blend is not as effective as whey to initiate a transient post prandial muscle anabolic response during a catabolic state in mini pigs.

scientific article published on 18 October 2017

Chronic Intake of Sucrose Accelerates Sarcopenia in Older Male Rats through Alterations in Insulin Sensitivity and Muscle Protein Synthesis

scientific article

Commentaries on Viewpoint: Muscle atrophy is not always sarcopenia.

scientific article published on August 2012

Contrarily to whey and high protein diets, dietary free leucine supplementation cannot reverse the lack of recovery of muscle mass after prolonged immobilization during ageing.

scientific article published on 20 February 2012

Curcumin treatment prevents increased proteasome and apoptosome activities in rat skeletal muscle during reloading and improves subsequent recovery.

scientific article

Cysteine fluxes across the portal-drained viscera of enterally fed minipigs: effect of an acute intestinal inflammation

scientific article published on 01 July 2010

Dairy products and inflammation: A review of the clinical evidence

scientific article published on 19 August 2015

Dietary proteins and amino acids in the control of the muscle mass during immobilization and aging: role of the MPS response.

scientific article published on 7 February 2017

Dietary supplementation with cysteine prevents adverse metabolic outcomes of repeated cures with paracetamol in old rats.

scientific article published on 27 November 2017

Differential effect of long-term leucine supplementation on skeletal muscle and adipose tissue in old rats: an insulin signaling pathway approach.

scientific article published on 7 April 2011

Effect of glucocorticoid excess on skeletal muscle and heart protein synthesis in adult and old rats

scientific article published on 01 March 1998

Effect of high chronic intake of sucrose on liver metabolism in aging rats. Modulation by rutin and micronutrients

scientific article published on 10 April 2018

Effect of treatment with dexamethasone on protein intake in adult and old Lou/c/jall rats

scientific article published on 26 January 2005

Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice.

scientific article

Effects of leucine supplementation and resistance exercise on dexamethasone-induced muscle atrophy and insulin resistance in rats.

scientific article published on 12 November 2011

Effects of meat cooking, and of ingested amount, on protein digestion speed and entry of residual proteins into the colon: a study in minipigs.

scientific article published on 12 April 2013

Effects of nutritional state, aging and high chronic intake of sucrose on brain protein synthesis in rats: modulation of it by rutin and other micronutrients

scientific article published on 01 May 2018

Effects of oat protein supplementation on skeletal muscle damage, inflammation and performance recovery following downhill running in untrained collegiate men

scientific article published on 01 September 2018

Effects of the nitric oxide donor SIN-1 on net hepatic glucose uptake in the conscious dog.

scientific article published on 20 November 2007

Efficacy of non-pharmacological interventions to treat malnutrition in older persons: A systematic review and meta-analysis. The SENATOR project ONTOP series and MaNuEL Knowledge Hub project

scientific article published on 02 November 2018

Erratum. The Transplantation of ω3 PUFA-Altered Gut Microbiota of fat-1 Mice to Wild-Type Littermates Prevents Obesity and Associated Metabolic Disorders. Diabetes 2018;67:1512-1523.

scientific article published on 19 November 2018

Evidence for an alteration of plasma and liver proteins response to dexamethasone in aging rats

scientific article published on 01 January 2001

Fructose Feeding during the Postabsorptive State Alters Body Composition and Spares Nitrogen in Protein-Energy-Restricted Old Rats.

scientific article published in January 2018

Glucagon's effect on liver protein metabolism in vivo.

scientific article

Glucocorticoid effects on insulin- and IGF-I-regulated muscle protein metabolism during aging

scientific article published on 01 January 1998

Glucocorticoid excess induces a prolonged leucine resistance on muscle protein synthesis in old rats.

scientific article published in September 2004

Glucocorticoid-induced insulin resistance of protein synthesis is independent of the rapamycin-sensitive pathways in rat skeletal muscle

scientific article published on 01 July 1999

Glucocorticoids regulate mRNA levels for subunits of the 19 S regulatory complex of the 26 S proteasome in fast-twitch skeletal muscles.

scientific article published on February 2004

High whey protein intake delayed the loss of lean body mass in healthy old rats, whereas protein type and polyphenol/antioxidant supplementation had no effects

scientific article

Impact of medication on protein and amino acid metabolism in the elderly: the sulfur amino acid and paracetamol case

scientific article published on 20 March 2018

Impaired Skeletal Muscle Branched-Chain Amino Acids Catabolism Contributes to Their Increased Circulating Levels in a Non-Obese Insulin-Resistant Fructose-Fed Rat Model

scientific article published on 08 February 2019

Important determinants to take into account to optimize protein nutrition in the elderly: solutions to a complex equation

scientific article published on 17 November 2020

In the elderly, meat protein assimilation from rare meat is lower than that from meat that is well done.

scientific article

Increased availability of leucine with leucine-rich whey proteins improves postprandial muscle protein synthesis in aging rats.

scientific article

Influence of low- and high-protein diets on insulin and insulin-like growth factor-1 binding to skeletal muscle and liver in the growing rat ⬇️

scientific article published on 01 January 1991

Insulin and amino acids both strongly participate to the regulation of protein metabolism.

scientific article published on January 2004

Insulin secretion-independent effects of GLP-1 on canine liver glucose metabolism do not involve portal vein GLP-1 receptors.

scientific article published on 28 July 2005

Insulin-Like Growth Factor I (IGF-I) and Insulin Binding to Erythrocytes of Normal Prepubertal Children and Adults ⬇️

scientific article published on November 1, 1991

Insulin-independent effects of GLP-1 on canine liver glucose metabolism: duration of infusion and involvement of hepatoportal region.

scientific article published on 16 March 2004

Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats

scientific article published on 01 March 1994

Interaction of a selective serotonin reuptake inhibitor with insulin in the control of hepatic glucose uptake in conscious dogs.

scientific article

Intestinal inflammation increases gastrointestinal threonine uptake and mucin synthesis in enterally fed minipigs.

scientific article published on 4 February 2009

Involvement of the rapamycin-sensitive pathway in the insulin regulation of muscle protein synthesis in streptozotocin-diabetic rats.

scientific article published in January 1999

Lack of muscle recovery after immobilization in old rats does not result from a defect in normalization of the ubiquitin-proteasome and the caspase-dependent apoptotic pathways

scientific article published on 29 November 2010

Leucine limitation regulates myf5 and myoD expression and inhibits myoblast differentiation.

scientific article published on 3 November 2011

Leucine supplementation in rats induced a delay in muscle IR/PI3K signaling pathway associated with overall impaired glucose tolerance.

scientific article

Lipid peroxidation and antioxidant status in experimental diabetes

scientific article published on 01 June 1999

Long-term dietary supplementation with cystathionine improves tissue glutathione in ageing rats

scientific article published on 29 October 2015

Long-term effects of leucine supplementation on body composition.

scientific article published on May 2010

Metabolic adaptations to HFHS overfeeding: how whole body and tissues postprandial metabolic flexibility adapt in Yucatan mini-pigs.

scientific article published on 27 August 2016

Metabolomics Reveals that the Type of Protein in a High-Fat Meal Modulates Postprandial Mitochondrial Overload and Incomplete Substrate Oxidation in Healthy Overweight Men

scientific article published on 01 June 2018

Modulation of skeletal muscle lactate metabolism following bacteremia by insulin or insulin-like growth factor-I: effects of pentoxifylline

scientific article published on 01 June 1997

Muscle wasting and resistance of muscle anabolism: the "anabolic threshold concept" for adapted nutritional strategies during sarcopenia.

scientific article published on 23 December 2012

Myostatin gene inactivation prevents skeletal muscle wasting in cancer

scientific article published on 21 October 2014

Neuregulin 1 improves glucose tolerance in adult and old rats

scientific article

Nitrogen- and energy-imbalanced diets affect hepatic protein synthesis and gluconeogenesis differently in growing lambs.

scientific article published on 11 February 2009

Nutritional regulation of the anabolic fate of amino acids within the liver in mammals: concepts arising from in vivo studies

scientific article published on June 2015

Pentoxifylline improves insulin action limiting skeletal muscle catabolism after infection.

scientific article published in October 1999

Peripheral Blood Mononuclear Cell Metabolism Acutely Adapted to Postprandial Transition and Mainly Reflected Metabolic Adipose Tissue Adaptations to a High-Fat Diet in Minipigs

scientific article published on 21 November 2018

Portal glucose delivery stimulates muscle but not liver protein metabolism ⬇️

scientific article published on September 25, 2012

Portal infusion of a selective serotonin reuptake inhibitor enhances hepatic glucose disposal in conscious dogs.

scientific article

Post Meal Energy Boluses Do Not Increase the Duration of Muscle Protein Synthesis Stimulation in Two Anabolic Resistant Situations.

scientific article published on 29 March 2019

Potentially modifiable determinants of malnutrition in older adults: A systematic review

scientific article published on 11 December 2018

Presence of low-grade inflammation impaired postprandial stimulation of muscle protein synthesis in old rats.

scientific article published on 14 April 2009

Protein feeding pattern, casein feeding, or milk-soluble protein feeding did not change the evolution of body composition during a short-term weight loss program.

scientific article

Reactive oxygen species enhance mitochondrial function, insulin sensitivity and glucose uptake in skeletal muscle of senescence accelerated prone mice SAMP8.

scientific article published on 9 October 2017

Resistant starch intake partly restores metabolic and inflammatory alterations in the liver of high-fat-diet-fed rats

scientific article published on 03 September 2013

Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging ⬇️

scientific article published on November 1, 1995

Similarities and interactions between the ageing process and high chronic intake of added sugars

scientific article published on 17 May 2017

Skeletal muscle proteolysis in aging.

scientific article published on January 2009

Slight chronic elevation of C-reactive protein is associated with lower aerobic fitness but does not impair meal-induced stimulation of muscle protein metabolism in healthy old men

scientific article published on 04 February 2015

Soluble Milk Proteins Improve Muscle Mass Recovery after Immobilization-Induced Muscle Atrophy in Old Rats but Do not Improve Muscle Functional Property Restoration.

scientific article published in January 2017

Spreading intake of a leucine-rich fast protein in energy-restricted overweight rats does not improve protein mass

scientific article published on 20 December 2011

The Transplantation of ω3 PUFA-Altered Gut Microbiota of fat-1 Mice to Wild-Type Littermates Prevents Obesity and Associated Metabolic Disorders

scientific article published on 23 May 2018

The delayed recovery of the remobilized rat tibialis anterior muscle reflects a defect in proliferative and terminal differentiation that impairs early regenerative processes

scientific article published on 31 March 2015

The effect of vagal cooling on canine hepatic glucose metabolism in the presence of hyperglycemia of peripheral origin

scientific article published on 01 June 2007

The nature of the ingested protein has no effect on lean body mass during energy restriction in overweight rats

scientific article published on 21 October 2010

The worsening of tibialis anterior muscle atrophy during recovery post-immobilization correlates with enhanced connective tissue area, proteolysis, and apoptosis.

scientific article

Therapeutic paracetamol treatment in older persons induces dietary and metabolic modifications related to sulfur amino acids.

scientific article published on 22 February 2011

Time Course of Molecular and Metabolic Events in the Development of Insulin Resistance in Fructose-Fed Rats.

scientific article published on 26 April 2016

Time-course changes in circulating branched-chain amino acid levels and metabolism in obese Yucatan minipig

scientific article published on 27 November 2017

Unilateral hindlimb casting induced a delayed generalized muscle atrophy during rehabilitation that is prevented by a whey or a high protein diet but not a free leucine-enriched diet

scientific article

Whey proteins are more efficient than casein in the recovery of muscle functional properties following a casting induced muscle atrophy

scientific article

List of works by Dominique Dardevet

4E-BP1 and 4E-BP2 double knockout mice are protected from aging-associated sarcopenia

A dietary supplementation with leucine and antioxidants is capable to accelerate muscle mass recovery after immobilization in adult rats

A meal with mixed soy/whey proteins is as efficient as a whey meal in counteracting the age-related muscle anabolic resistance only if the protein content and leucine levels are increased

A mix of dietary fermentable fibers improves lipids handling by the liver of overfed minipigs

Altered responses in skeletal muscle protein turnover during aging in anabolic and catabolic periods.

Arterio-venous metabolomics exploration reveals major changes across liver and intestine in the obese Yucatan minipig

Assessment of protein modifications in liver of rats under chronic treatment with paracetamol (acetaminophen) using two complementary mass spectrometry-based metabolomic approaches

At same leucine intake, a whey/plant protein blend is not as effective as whey to initiate a transient post prandial muscle anabolic response during a catabolic state in mini pigs.

Chronic Intake of Sucrose Accelerates Sarcopenia in Older Male Rats through Alterations in Insulin Sensitivity and Muscle Protein Synthesis

Commentaries on Viewpoint: Muscle atrophy is not always sarcopenia.

Contrarily to whey and high protein diets, dietary free leucine supplementation cannot reverse the lack of recovery of muscle mass after prolonged immobilization during ageing.

Curcumin treatment prevents increased proteasome and apoptosome activities in rat skeletal muscle during reloading and improves subsequent recovery.

Cysteine fluxes across the portal-drained viscera of enterally fed minipigs: effect of an acute intestinal inflammation

Dairy products and inflammation: A review of the clinical evidence

Dietary proteins and amino acids in the control of the muscle mass during immobilization and aging: role of the MPS response.

Dietary supplementation with cysteine prevents adverse metabolic outcomes of repeated cures with paracetamol in old rats.

Differential effect of long-term leucine supplementation on skeletal muscle and adipose tissue in old rats: an insulin signaling pathway approach.

Effect of glucocorticoid excess on skeletal muscle and heart protein synthesis in adult and old rats

Effect of high chronic intake of sucrose on liver metabolism in aging rats. Modulation by rutin and micronutrients

Effect of treatment with dexamethasone on protein intake in adult and old Lou/c/jall rats

Effects of high-intensity interval training and moderate-intensity continuous training on glycaemic control and skeletal muscle mitochondrial function in db/db mice.

Effects of leucine supplementation and resistance exercise on dexamethasone-induced muscle atrophy and insulin resistance in rats.

Effects of meat cooking, and of ingested amount, on protein digestion speed and entry of residual proteins into the colon: a study in minipigs.

Effects of nutritional state, aging and high chronic intake of sucrose on brain protein synthesis in rats: modulation of it by rutin and other micronutrients

Effects of oat protein supplementation on skeletal muscle damage, inflammation and performance recovery following downhill running in untrained collegiate men

Effects of the nitric oxide donor SIN-1 on net hepatic glucose uptake in the conscious dog.

Efficacy of non-pharmacological interventions to treat malnutrition in older persons: A systematic review and meta-analysis. The SENATOR project ONTOP series and MaNuEL Knowledge Hub project

Erratum. The Transplantation of ω3 PUFA-Altered Gut Microbiota of fat-1 Mice to Wild-Type Littermates Prevents Obesity and Associated Metabolic Disorders. Diabetes 2018;67:1512-1523.

Evidence for an alteration of plasma and liver proteins response to dexamethasone in aging rats

Fructose Feeding during the Postabsorptive State Alters Body Composition and Spares Nitrogen in Protein-Energy-Restricted Old Rats.

Glucagon's effect on liver protein metabolism in vivo.

Glucocorticoid effects on insulin- and IGF-I-regulated muscle protein metabolism during aging

Glucocorticoid excess induces a prolonged leucine resistance on muscle protein synthesis in old rats.

Glucocorticoid-induced insulin resistance of protein synthesis is independent of the rapamycin-sensitive pathways in rat skeletal muscle

Glucocorticoids regulate mRNA levels for subunits of the 19 S regulatory complex of the 26 S proteasome in fast-twitch skeletal muscles.

High whey protein intake delayed the loss of lean body mass in healthy old rats, whereas protein type and polyphenol/antioxidant supplementation had no effects

Impact of medication on protein and amino acid metabolism in the elderly: the sulfur amino acid and paracetamol case

Impaired Skeletal Muscle Branched-Chain Amino Acids Catabolism Contributes to Their Increased Circulating Levels in a Non-Obese Insulin-Resistant Fructose-Fed Rat Model

Important determinants to take into account to optimize protein nutrition in the elderly: solutions to a complex equation

In the elderly, meat protein assimilation from rare meat is lower than that from meat that is well done.

Increased availability of leucine with leucine-rich whey proteins improves postprandial muscle protein synthesis in aging rats.

Influence of low- and high-protein diets on insulin and insulin-like growth factor-1 binding to skeletal muscle and liver in the growing rat ⬇️

Insulin and amino acids both strongly participate to the regulation of protein metabolism.

Insulin secretion-independent effects of GLP-1 on canine liver glucose metabolism do not involve portal vein GLP-1 receptors.

Insulin-Like Growth Factor I (IGF-I) and Insulin Binding to Erythrocytes of Normal Prepubertal Children and Adults ⬇️

Insulin-independent effects of GLP-1 on canine liver glucose metabolism: duration of infusion and involvement of hepatoportal region.

Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats

Interaction of a selective serotonin reuptake inhibitor with insulin in the control of hepatic glucose uptake in conscious dogs.

Intestinal inflammation increases gastrointestinal threonine uptake and mucin synthesis in enterally fed minipigs.

Involvement of the rapamycin-sensitive pathway in the insulin regulation of muscle protein synthesis in streptozotocin-diabetic rats.

Lack of muscle recovery after immobilization in old rats does not result from a defect in normalization of the ubiquitin-proteasome and the caspase-dependent apoptotic pathways

Leucine limitation regulates myf5 and myoD expression and inhibits myoblast differentiation.

Leucine supplementation in rats induced a delay in muscle IR/PI3K signaling pathway associated with overall impaired glucose tolerance.

Lipid peroxidation and antioxidant status in experimental diabetes

Long-term dietary supplementation with cystathionine improves tissue glutathione in ageing rats

Long-term effects of leucine supplementation on body composition.

Metabolic adaptations to HFHS overfeeding: how whole body and tissues postprandial metabolic flexibility adapt in Yucatan mini-pigs.

Metabolomics Reveals that the Type of Protein in a High-Fat Meal Modulates Postprandial Mitochondrial Overload and Incomplete Substrate Oxidation in Healthy Overweight Men

Modulation of skeletal muscle lactate metabolism following bacteremia by insulin or insulin-like growth factor-I: effects of pentoxifylline

Muscle wasting and resistance of muscle anabolism: the "anabolic threshold concept" for adapted nutritional strategies during sarcopenia.

Myostatin gene inactivation prevents skeletal muscle wasting in cancer

Neuregulin 1 improves glucose tolerance in adult and old rats

Nitrogen- and energy-imbalanced diets affect hepatic protein synthesis and gluconeogenesis differently in growing lambs.

Nutritional regulation of the anabolic fate of amino acids within the liver in mammals: concepts arising from in vivo studies

Pentoxifylline improves insulin action limiting skeletal muscle catabolism after infection.

Peripheral Blood Mononuclear Cell Metabolism Acutely Adapted to Postprandial Transition and Mainly Reflected Metabolic Adipose Tissue Adaptations to a High-Fat Diet in Minipigs

Portal glucose delivery stimulates muscle but not liver protein metabolism ⬇️

Portal infusion of a selective serotonin reuptake inhibitor enhances hepatic glucose disposal in conscious dogs.

Post Meal Energy Boluses Do Not Increase the Duration of Muscle Protein Synthesis Stimulation in Two Anabolic Resistant Situations.

Potentially modifiable determinants of malnutrition in older adults: A systematic review

Presence of low-grade inflammation impaired postprandial stimulation of muscle protein synthesis in old rats.

Protein feeding pattern, casein feeding, or milk-soluble protein feeding did not change the evolution of body composition during a short-term weight loss program.

Reactive oxygen species enhance mitochondrial function, insulin sensitivity and glucose uptake in skeletal muscle of senescence accelerated prone mice SAMP8.

Resistant starch intake partly restores metabolic and inflammatory alterations in the liver of high-fat-diet-fed rats

Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging ⬇️

Similarities and interactions between the ageing process and high chronic intake of added sugars

Skeletal muscle proteolysis in aging.

Slight chronic elevation of C-reactive protein is associated with lower aerobic fitness but does not impair meal-induced stimulation of muscle protein metabolism in healthy old men

Soluble Milk Proteins Improve Muscle Mass Recovery after Immobilization-Induced Muscle Atrophy in Old Rats but Do not Improve Muscle Functional Property Restoration.