Search filters

List of works by Bruno Imbimbo

1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.

scientific article

A 25-week placebo-controlled study of eptastigmine in patients with Alzheimer disease

scientific article published in December 1998

A 6-month, double-blind, placebo-controlled trial of eptastigmine in Alzheimer's disease

scientific article published in January 2000

A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease

scientific article published on 31 March 2020

A critical appraisal of amyloid-β-targeting therapies for Alzheimer disease

scientific article published on 01 February 2019

A new criterion for selection of pharmacokinetic multiexponential equations

scientific article published in September 1988

A patient-side technique for real-time measurement of acetylcholinesterase activity during monitoring of eptastigmine treatment.

scientific article published in June 1995

Acetylcholinesterase assay may predict cognitive response of Alzheimer patients to eptastigmine treatment

scientific article published on 01 November 1998

Action of mifentidine on the secretory response to sham feeding and pentagastrin and on serum gastrin in duodenal ulcer patients

scientific article published on 01 January 1987

Acute administration of hexarelin stimulates GH secretion during day and night in normal men

scientific article published on 01 March 1997

Acute changes in urinary radiocalcium following glucocorticoids administration in man

scientific article published on 01 January 1984

Acute effect of prednisone and deflazacort on glucose tolerance in prediabetic subjects

scientific article published on 01 January 1982

Advances in the identification of γ-secretase inhibitors for the treatment of Alzheimer's disease.

scientific article published on 14 December 2011

Alcohol consumption in mild cognitive impairment and dementia: harmful or neuroprotective?

scientific article published on 07 March 2012

Aluminum in the Diet and Alzheimer's Disease: From Current Epidemiology to Possible Disease-Modifying Treatment

scholarly article by Vincenza Frisardi et al published 24 March 2010 in Journal of Alzheimer's Disease

Aluminum in the diet and Alzheimer's disease: from current epidemiology to possible disease-modifying treatment

scientific article published on January 2010

Amyloid deposition in a mouse model humanized at the transthyretin and retinol-binding protein 4 loci.

scientific article

Amyloid-based immunotherapy for Alzheimer's disease in the time of prevention trials: the way forward

scientific article published on 04 February 2014

Amyloid-directed monoclonal antibodies for the treatment of Alzheimer's disease: the point of no return?

scientific article published on 30 June 2014

Amyloid-related imaging abnormalities associated with immunotherapy in Alzheimer’s disease patients

Amyloid-β immunotherapy for alzheimer disease: Is it now a long shot?

scientific article published on 28 January 2019

An update on the efficacy of non-steroidal anti-inflammatory drugs in Alzheimer's disease

scientific article published on August 2009

Angiotensin-converting enzyme inhibitors and incidence of mild cognitive impairment. The Italian Longitudinal Study on Aging

scientific article published on 28 December 2011

Anti-β-amyloid immunotherapy for Alzheimer's disease: focus on bapineuzumab

scientific article published on December 2011

Are NSAIDs useful to treat Alzheimer's disease or mild cognitive impairment?

scientific article published on 21 May 2010

Are antibodies directed against amyloid-β (Aβ) oligomers the last call for the Aβ hypothesis of Alzheimer's disease?

scientific article published on 01 January 2019

Are γ-secretase inhibitors detrimental for Alzheimer's disease patients?

scientific article

Arginine and growth hormone-releasing hormone restore the blunted growth hormone-releasing activity of hexarelin in elderly subjects

Arginine and growth hormone-releasing hormone restore the blunted growth hormone-releasing activity of hexarelin in elderly subjects.

scientific article

BACE inhibitors in clinical development for the treatment of Alzheimer's disease

article

Bapineuzumab: anti-β-amyloid monoclonal antibodies for the treatment of Alzheimer's disease.

scientific article

Beyond the neurotransmitter-focused approach in treating Alzheimer's disease: drugs targeting beta-amyloid and tau protein

scientific article published on December 2009

Biliary excretion of rufloxacin in humans.

scientific article

Bipolar Disorder and Frontotemporal Dementia: An Intriguing Association

scientific article

Bone loss after glucocorticoid therapy

scientific article published on 01 July 1984

CHF3381, a N-methyl-D-aspartate receptor antagonist and monoamine oxidase-A inhibitor, attenuates secondary hyperalgesia in a human pain model.

scientific article

CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid.

scientific article published on 22 October 2014

CHF5074 (CSP-1103) stabilizes human transthyretin in mice humanized at the transthyretin and retinol-binding protein loci.

scientific article published on 26 February 2015

CHF5074 and LY450139 sub-acute treatments differently affect cortical extracellular glutamate levels in pre-plaque Tg2576 mice

scientific article

CHF5074 reduces biomarkers of neuroinflammation in patients with mild cognitive impairment: a 12-week, double-blind, placebo-controlled study.

scientific article published on September 2013

CHF5074 restores visual memory ability and pre-synaptic cortical acetylcholine release in pre-plaque Tg2576 mice.

scientific article published on 28 January 2013

CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.

scientific article published on March 2009

CHF5074, a novel gamma-secretase modulator, restores hippocampal neurogenesis potential and reverses contextual memory deficit in a transgenic mouse model of Alzheimer's disease

scientific article published in January 2010

CSP-1103 (CHF5074) stabilizes human transthyretin in healthy human subjects.

scientific article published on 10 April 2017

Cardiac autonomic dysfunction in patients with Alzheimer disease: possible pathogenetic mechanisms.

scientific article published in December 1998

Cimetropium bromide as a relaxant for the radiological examination of the stomach and duodenum

article by A Frigerio et al published 1 January 1986 in Current Medical Research and Opinion

Clinical equivalence of a new glucocorticoid, deflazacort and prednisone in rheumatoid arthritis and S.L.E. patients

scientific article published on 01 January 1984

Coffee Consumption Habits and the Risk of Mild Cognitive Impairment: The Italian Longitudinal Study on Aging

scientific article published on August 2015

Colonic mass movements in idiopathic chronic constipation

scientific article

Comparative study of the effects of cimetropium bromide and atropine on human esophageal motor functions

scientific article published on 01 January 1989

Comparison of acute and subacute effects of deflazacort and prednisone on glucose metabolism in man ⬇️

scientific article published on January 1, 1984

Comparison of growth retarding effects induced by two different glucocorticoids in prepubertal sick children: an interim long-term analysis

scientific article published on 01 April 1991

Comparison of pharmacological modulation of APP metabolism in primary chicken telencephalic neurons and in a human neuroglioma cell line

scientific article

Comparison of subacute effects of oxazacort and prednisone on mineral metabolism in man

scientific article published on 01 January 1980

Comparison of the effects of growth hormone-releasing hormone and hexarelin, a novel growth hormone-releasing peptide-6 analog, on growth hormone secretion in humans with or without glucocorticoid excess

scientific article published on 01 August 1995

Comparison of two glucocorticoid preparations (deflazacort and prednisone) in the treatment of immune-mediated diseases

scientific article published on 01 January 1993

Conformation-sensitive antibodies against alzheimer amyloid-beta by immunization with a thioredoxin-constrained B-cell epitope peptide

scientific article published on 31 January 2007

Deflazacort and skeletal, phosphate and glucose metabolism in monkeys

scientific article published on 01 January 1984

Deflazacort versus prednisone diabetogenic effect evaluated by glucose clamp and compartmental analysis

scientific article published on January 1, 1984

Development of disease-modifying drugs for frontotemporal dementia spectrum disorders

scientific article published on 23 March 2020

Diet and Alzheimer’s disease risk factors or prevention: the current evidence

scientific article

Dietary unsaturated fatty acids and risk of mild cognitive impairment.

scientific article published in January 2010

Discontinued disease-modifying therapies for Alzheimer's disease: status and future perspectives

scientific article published on 11 July 2020

Discontinuous oral absorption of cimetropium bromide, a new antispasmodic drug

scientific article published on 01 July 1986

Discovery of diaryl imidazolidin-2-one derivatives, a novel class of muscarinic M3 selective antagonists (Part 1).

scientific article published on 13 March 2007

Discovery of diaryl imidazolidin-2-one derivatives, a novel class of muscarinic M3 selective antagonists (Part 2).

scientific article published on 13 March 2007

Disease-modifying approach to the treatment of Alzheimer's disease: from alpha-secretase activators to gamma-secretase inhibitors and modulators.

scientific article published on January 2009

Disease-modifying therapies for tauopathies: agents in the pipeline

scientific article published on 25 April 2019

Distension-stimulated propagated contractions in human colon

scientific article

Do BACE inhibitor failures in Alzheimer patients challenge the amyloid hypothesis of the disease?

scientific article published on 27 May 2019

Do anti-amyloid-β drugs affect neuropsychiatric status in Alzheimer's disease patients?

scientific article published on 24 August 2019

Drug-induced reductions in brain amyloid-β levels may adversely affect cognition and behavior by a disruption of functional connectivity homeostasis

scientific article published on 24 July 2019

Edrophonium chloride for testing colonic contractile activity in man

scientific article published on 01 March 1991

Effect of food on the absorption of eptastigmine

scientific article published on 01 May 1998

Effect of mifentidine on peptone meal-stimulated gastric acid secretion and plasma gastrin levels in duodenal ulcer patients

scientific article published in August 1988

Effect of single oral doses of prednisone and deflazacort on human lymphocyte distribution and functions. Analysis with monoclonal antibodies

scientific article published on 01 January 1984

Effects of a new heterocyclic glucocorticoid, deflazacort (DFC), on the functions of lymphocytes from patients with rheumatoid arthritis (RA)

scientific article published on 01 January 1987

Effects of cimetropium bromide on gallbladder contraction in response to oral and intraduodenal olive oil

scientific article published on 01 January 1990

Effects of magnesium-aluminum hydroxide antacid on absorption of rufloxacin.

scientific article

Effects of pirenzepine and atropine on gastroduodenal motor patterns in duodenal ulcer patients

scientific article published on 01 November 1986

Effects of prednisone and deflazacort on mineral metabolism and parathyroid hormone activity in humans

scientific article published on 01 May 1984

Effects of prednisone and deflazacort on vertebral bone mass

scientific article published on 01 December 1985

Efficacy and safety of eptastigmine for the treatment of patients with Alzheimer's disease

scientific article published in March 1999

Efficacy and safety studies of gantenerumab in patients with Alzheimer's disease

scientific article published on August 2014

Efficacy of cimetropium bromide as pre-medication for double-contrast barium enema

scientific article published on 01 November 1988

Efficiency of different criteria for selecting pharmacokinetic multiexponential equations

scientific article published in March 1991

Electrophysiological and metabolic effects of CHF5074 in the hippocampus: Protection against in vitro ischemia

scientific article published on 12 March 2014

Emerging drugs to reduce abnormal β-amyloid protein in Alzheimer's disease patients.

scientific article published on 28 September 2016

Eptastigmine augments basal and GHRH-stimulated growth hormone release in young and old dogs

scientific article published on 01 January 1993

Examination of level of knowledge in Italian general practitioners attending an education session on diagnosis and management of the early stage of Alzheimer's disease: pass or fail?

scientific article

Frailty syndrome and the risk of vascular dementia: the Italian Longitudinal Study on Aging

scientific article

Gallbladder hypokinesia and normal gastric emptying of liquids in patients with dyspeptic symptoms. A double-blind placebo-controlled clinical trial with cisapride

scientific article

Ganstigmine and donepezil improve neurodegeneration in AD11 antinerve growth factor transgenic mice

scientific article

Gastric acid and pepsin secretion after single oral doses of mifentidine in healthy subjects

scientific article published on 01 September 1988

Gerontechnology for demented patients: smart homes for smart aging.

scientific article published in January 2011

Growth hormone-releasing activity of hexarelin in humans. A dose-response study

scientific article published on 01 January 1994

Growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, after intravenous, subcutaneous, intranasal, and oral administration in man.

scientific article

Growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, before and during puberty

scientific article published on 01 April 1995

Hemodynamic effects of MF 10058, a new cardioselective muscarinic M(2) receptor antagonist, in conscious dogs

scientific article

Hexarelin, a novel GHRP-6 analog, counteracts the inhibitory effect of hydrocortisone on growth hormone secretion in acromegaly

scientific article published on August 1995

Hexarelin, a potent GHRP analogue: interactions with GHRH and clonidine in young and aged dogs

scientific article published on 01 January 1995

High performance liquid chromatography and preliminary pharmacokinetics of rufloxacin and its metabolites N-desmethylrufloxacin and rufloxacinsulfoxide in plasma and urine of humans

scientific article published on 01 January 1992

High throughput screening of beta-amyloid secretion inhibitors using homogenous time-resolved fluorescence

scientific article

High-performance liquid chromatography and preliminary pharmacokinetics of rufloxacin and its metabolites, N-desmethylrufloxacin and rufloxacinsulfoxide, in urine of rhesus monkey Macaca mulatta

scientific article published on 01 January 1992

Immunotherapy for Alzheimer's disease: from anti-β-amyloid to tau-based immunization strategies.

scientific article published on February 2012

Impaired colonic motor response to cholinergic stimulation in patients with severe chronic idiopathic (slow transit type) constipation

scientific article published on 01 June 1993

In vitro and ex vivo effects of different corticosteroids on polymorphonuclear leukocyte functions

scientific article published on 01 January 1984

In vitro and in vivo profiling of CHF5022 and CHF5074 Two beta-amyloid1-42 lowering agents.

scientific article published on 16 January 2007

Inhibition of caerulein-induced gall bladder emptying by cimetropium bromide in humans

scientific article published on 01 January 1989

Inter- and intrasubject variabilities in the pharmacokinetics of rufloxacin after single oral administration to healthy volunteers

scientific article published on February 1991

Interacting with γ-secretase for treating Alzheimer's disease: from inhibition to modulation.

scientific article published on January 2011

Interleukin 6-174 G/C promoter and variable number of tandem repeats (VNTR) gene polymorphisms in sporadic Alzheimer's disease.

scientific article published on 6 November 2009

Investigational BACE inhibitors for the treatment of Alzheimer's disease

scientific article published on 29 October 2019

Is insulin resistant brain state a central feature of the metabolic-cognitive syndrome?

scientific article published in January 2010

Is there still any hope for amyloid-based immunotherapy for Alzheimer's disease?

scientific article published on March 2014

Kinetics of cholinesterase inhibition by eptastigmine in man.

scientific article published in January 1991

Lack of effect of hexarelin on TRH-induced TSH response in normal adult man.

scientific article published on April 1998

Late-life depression, mild cognitive impairment, and dementia: possible continuum?

scientific article published on February 2010

Longterm treatment of irritable bowel syndrome with cimetropium bromide: a double blind placebo controlled clinical trial

scientific article

Manometric evaluation of cimetropium bromide activity in patients with the nutcracker oesophagus

scientific article published in November 1988

Maximum tolerated dose and pharmacodynamics of eptastigmine in elderly healthy volunteers

scientific article published in July 1998

Mechanism of action of hexarelin and GHRP-6: analysis of the involvement of GHRH and somatostatin in the rat

scientific article published on 01 January 1995

Mechanistic pharmacokinetic and pharmacodynamic modeling of CHF3381 (2-[(2,3-dihydro-1H-inden-2-yl)amino]acetamide monohydrochloride), a novel N-methyl-D-aspartate antagonist and monoamine oxidase-A inhibitor in healthy subjects.

scientific article published on 25 January 2005

Medicinal chemistry and therapeutic potential of muscarinic M3 antagonists.

scientific article

Mediterranean diet in predementia and dementia syndromes.

scientific article published on August 2011

Metabolic modulation of the growth hormone-releasing activity of hexarelin in man.

scientific article published on January 1995

Metabolic syndrome and cognitive impairment: current epidemiology and possible underlying mechanisms

scientific article published on January 2010

Metabolic syndrome, mild cognitive impairment, and dementia.

scientific article published on August 2011

Metabolic-cognitive syndrome: metabolic approach for the management of Alzheimer's disease risk

scientific article published in January 2012

Midlife Metabolic Profile and the Risk of Late-Life Cognitive Decline.

scientific article published on 30 May 2017

Modulation of growth hormone-releasing activity of hexarelin in man

scientific article published on 01 January 1995

Monoclonal antibodies against β-amyloid (Aβ) for the treatment of Alzheimer's disease: the Aβ target at a crossroads

scientific article published on 19 April 2011

Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice.

scientific article

Multiple-dose pharmacokinetics and safety of rufloxacin in normal volunteers

scientific article published on June 1992

Multiple-dose pharmacokinetics of rufloxacin in patients with cirrhosis

scientific article published on 01 October 1993

Neuroprotective and Anti-Apoptotic Effects of CSP-1103 in Primary Cortical Neurons Exposed to Oxygen and Glucose Deprivation

scientific article published on 18 January 2017

Nutraceutical properties of Mediterranean diet and cognitive decline: possible underlying mechanisms.

scientific article published on January 2010

Pathophysiology of Alzheimer's disease.

scientific article

Peripheral antioxidant markers in mild cognitive impairment and its progression to dementia

scientific article published on January 2010

Pharmacodynamic monitoring of eptastigmine in capillary blood.

scientific article published in January 1996

Pharmacodynamic-tolerability relationships of cholinesterase inhibitors for Alzheimer's disease.

scientific article

Pharmacodynamics and pharmacokinetics of eptastigmine in elderly subjects

scientific article published on 01 January 1993

Pharmacodynamics of a long acting depot preparation of avorelin in patients with prostate cancer. Avorelin Study Group

scientific article published on 01 December 1999

Pharmacokinetics and pharmacodynamics of CHF5074 after short-term administration in healthy subjects.

scientific article published in July 2013

Pharmacokinetics and tissue penetration of rufloxacin, a long acting quinolone antimicrobial agent

scientific article published on 01 December 1991

Pharmacokinetics of mifentidine after single and multiple oral administration to healthy volunteers.

scientific article

Pharmacokinetics of rufloxacin in healthy volunteers after repeated oral doses

scientific article published on January 1991

Pharmacokinetics of rufloxacin in patients with impaired renal function

scientific article

Pharmacokinetics of rufloxacin once daily in patients with lower respiratory tract infections

scientific article

Pharmacological management of dementia with Lewy bodies with a focus on zonisamide for treating parkinsonism

scientific article published on 06 October 2020

Pharmacological targeting of the β-amyloid precursor protein intracellular domain.

scientific article published on 09 April 2014

Polymorphisms in glutathione S-transferase omega-1 gene and increased risk of sporadic Alzheimer disease

scientific article published on 6 September 2010

Polyunsaturated fatty acid and S-adenosylmethionine supplementation in predementia syndromes and Alzheimer's disease: a review

scientific article published on 22 May 2009

Potency ratio, clinical equivalence, and wasting ratio estimate of different glucocorticoids

scientific article published on 01 December 1991

Progresses in treating agitation: a major clinical challenge in Alzheimer's disease

scientific article published on 21 September 2015

Prolonged effects of cholinesterase inhibition with eptastigmine on the cerebral blood flow-metabolism ratio of normal rats

scientific article

Promising therapies for the treatment of frontotemporal dementia clinical phenotypes: from symptomatic to disease-modifying drugs

scientific article published on 19 April 2019

REVIEW: γ-Secretase inhibitors for the treatment of Alzheimer's disease: The current state.

scientific article published on 16 June 2010

Rapid potentiometric determination of cholinesterases in plasma and red cells: application to eptastigmine monitoring

scientific article published on 01 June 1993

Receptor for advanced glycation end products contributes to postnatal pulmonary development and adult lung maintenance program in mice.

scientific article published on 9 November 2012

Reduction by cimetropium bromide of the colonic motor response to eating in patients with the irritable bowel syndrome.

scientific article

Relationship between pharmacodynamic activity and cognitive effects of eptastigmine in patients with Alzheimer's disease. Eptastigmine Study Group.

scientific article published on August 1996

Relationship between pharmacokinetics and pharmacodynamics of eptastigmine in young healthy volunteers

scientific article published on 01 March 1995

Relationships of Dietary Patterns, Foods, and Micro- and Macronutrients with Alzheimer's Disease and Late-Life Cognitive Disorders: A Systematic Review.

scientific article

Reversible Cognitive Frailty, Dementia, and All-Cause Mortality. The Italian Longitudinal Study on Aging

scientific article published on January 2017

Safety and pharmacokinetics of mifentidine after increasing oral doses in healthy subjects

scientific article published on 01 January 1988

Safety, pharmacokinetics, and pharmacodynamics of CHF 3381, a novel N-methyl-D-aspartate antagonist, after single oral doses in healthy subjects

scientific article published in August 2003

Sensitivity of bone histomorphometry in the diagnosis of metabolic bone diseases

scientific article published on 01 November 1989

Should drug discovery scientists still embrace the amyloid hypothesis for Alzheimer's disease or should they be looking elsewhere?

scientific article published on 20 July 2020

Social Dysfunction in Older Age and Relationships with Cognition, Depression, and Apathy: The GreatAGE Study

scientific article published on 01 January 2018

Solanezumab for the treatment of mild-to-moderate Alzheimer's disease

scientific article published on February 2012

Statural growth and skeletal maturation in rheumatic prepubertal children treated with a third generation glucocorticoid (deflazacort) versus prednisone. An interim study

scientific article published on January 1991

Steady-state pharmacokinetics and pharmacodynamics of CHF3381, a novel antineuropathic pain agent, in healthy subjects

scientific article published on April 2005

Steady-state pharmacokinetics of rufloxacin in elderly patients with lower respiratory tract infections

scientific article published on February 1, 1992

Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors

scientific article

Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin

scientific article published on 29 August 2019

Suicide in two patients with a diagnosis of probable Alzheimer disease.

scientific article published in April 1999

Suppressive effect of chronic glucocorticoid treatment on circulating calcitonin in man ⬇️

scientific article published on 01 May 1982

Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion

scientific article published in September 2005

Synthesis of new cardioselective M2 muscarinic receptor antagonists

scientific article published on 01 November 2000

Tau aggregation inhibitors: the future of Alzheimer's pharmacotherapy?

scientific article published on 25 January 2016

Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's Disease

scientific article published in 2016

Tau-based therapeutics for Alzheimer's disease: active and passive immunotherapy

scientific article published in September 2016

Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium

scientific article published on 28 January 2016

The effect of hexarelin on growth hormone (GH) secretion in patients with GH deficiency

scientific article published on September 1995

The growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, in short normal and obese children and in hypopituitary subjects

scientific article published on 01 February 1995

The long-term efficacy and safety of two different corticosteroids in chronic sarcoidosis

scientific article published on September 1997

The penetration of rufloxacin into sites of potential infection in the respiratory tract.

scientific article

The pharmacokinetics and pharmacodynamics of dermatan sulphate MF701 during haemodialysis for chronic renal failure

scientific article

The potential of solanezumab and gantenerumab to prevent Alzheimer's disease in people with inherited mutations that cause its early onset

scientific article published on 16 October 2017

The potential role of non-steroidal anti-inflammatory drugs in treating Alzheimer's disease

scientific article (publication date: November 2004)

The protective effect of ganstigmine against amyloid beta 25-35 neurotoxicity on chicken cortical neurons is independent from the cholinesterase inhibition

scientific article published in May 2003

The use of cimetropii bromidum as premedication for endoscopy of the upper gastro-intestinal tract: a double-blind controlled clinical trial

scientific article published in January 1985

The γ-secretase modulator CHF5074 reduces the accumulation of native hyperphosphorylated tau in a transgenic mouse model of Alzheimer's disease

scientific article published on 22 December 2010

The γ-secretase modulator CHF5074 restores memory and hippocampal synaptic plasticity in plaque-free Tg2576 mice.

scientific article published in January 2011

Therapeutic effect of CHF5074, a new γ-secretase modulator, in a mouse model of scrapie

scientific article published in January 2012

Therapeutic intervention for Alzheimer's disease with γ-secretase inhibitors: still a viable option?

scientific article published on 11 January 2011

Therapeutic potential of gamma-secretase inhibitors and modulators

scientific article

Time to test antibacterial therapy in Alzheimer's disease

scientific article published on 01 October 2019

Towards disease-modifying treatment of Alzheimer's disease: drugs targeting beta-amyloid.

scientific article published on February 2010

Toxicity of beta-amyloid vaccination in patients with Alzheimer's disease

scientific article published on 01 June 2002

Transverse and sigmoid colon motility in healthy humans: effects of eating and of cimetropium bromide

scientific article published in January 1987

Two-year treatment of Alzheimer's disease with eptastigmine. The Eptastigmine Study Group

scientific article published in March 1999

Urinary excretion of cimetropium bromide after multiple oral doses

scientific article published on 01 January 1987

Why did tarenflurbil fail in Alzheimer's disease?

scientific article published in January 2009

γ -Secretase Pharmacology: What Pharmacology Will Work for Alzheimer's Disease?

scientific article published on 18 April 2013

γ-secretase inhibitors and modulators for the treatment of Alzheimer's disease: disappointments and hopes

scientific article published on January 2011

Paulina is supported by:

About Paulina

Help