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List of works by Freddie Hamdy

10-Year Outcomes in Localized Prostate Cancer

scientific article

A Collaborative Analysis of Individual Participant Data from 19 Prospective Studies Assesses Circulating Vitamin D and Prostate Cancer Risk

scientific article published on 13 November 2018

A Meta-analysis of Individual Participant Data Reveals an Association between Circulating Levels of IGF-I and Prostate Cancer Risk

scientific article

A Peer Review Intervention for Monitoring and Evaluating sites (PRIME) that improved randomized controlled trial conduct and performance

scientific article published on 15 January 2011

A comparison of socio-demographic and psychological factors between patients consenting to randomisation and those selecting treatment (the ProtecT study).

scientific article published on 4 May 2006

A cross-sectional analysis of the association between diet and insulin-like growth factor (IGF)-I, IGF-II, IGF-binding protein (IGFBP)-2, and IGFBP-3 in men in the United Kingdom

scientific article published on 21 April 2012

A genetic risk score to guide age-specific, personalized prostate cancer screening

A genetic risk score to personalize prostate cancer screening, applied to population data

scientific article published on 24 June 2020

A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk

scientific article published on 29 July 2013

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

scientific article published on 25 September 2011

A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer

scientific article published on 14 September 2014

A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease

scientific article

A prospective cohort and extended comprehensive-cohort design provided insights about the generalizability of a pragmatic trial: the ProtecT prostate cancer trial

scientific article published on 26 December 2017

Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT

scientific article published on 01 August 2020

Active monitoring, radical prostatectomy, or radiotherapy for localised prostate cancer: study design and diagnostic and baseline results of the ProtecT randomised phase 3 trial

scientific article

Acupuncture in urological practice—A survey of urologists in England ⬇️

scientific article published on 03 December 2010

Addressing patient treatment preferences at trial recruitment

scientific article

Adherence to dietary and lifestyle recommendations and prostate cancer risk in the prostate testing for cancer and treatment (ProtecT) trial

scientific article

Alcohol consumption and PSA-detected prostate cancer risk--a case-control nested in the ProtecT study

scientific article published on 25 October 2012

Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study

scientific article published on 19 September 2016

Apoptosis regulating genes in prostate cancer (review) ⬇️

scientific article published on May 1, 1998

Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data

scientific article published on 25 September 2017

Assessing the role of insulin-like growth factors and binding proteins in prostate cancer using Mendelian randomization: Genetic variants as instruments for circulating levels

scientific article published on 26 May 2016

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scientific article published on 11 June 2018

Association between Prostinogen (KLK15) genetic variants and prostate cancer risk and aggressiveness in Australia and a meta-analysis of GWAS data

scientific article

Association of diabetes mellitus with prostate cancer: nested case-control study (Prostate testing for cancer and treatment study).

scientific article published on 5 April 2010

Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis

scientific article published on 25 August 2009

Associations between an obesity related genetic variant (FTO rs9939609) and prostate cancer risk

scientific article

Associations of Lifestyle Factors and Anthropometric Measures with Repeat PSA Levels During Active Surveillance/Monitoring

scientific article published on 02 August 2012

Associations of adiponectin and leptin with stage and grade of PSA-detected prostate cancer: the ProtecT study

scientific article published on 8 December 2012

Associations of aspirin, nonsteroidal anti-inflammatory drug and paracetamol use with PSA-detected prostate cancer: findings from a large, population-based, case-control study (the ProtecT study).

scientific article published in March 2011

Associations of circulating 25-hydroxyvitamin D with prostate cancer diagnosis, stage and grade

scientific article

Associations of circulating 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, and vitamin D pathway genes with prostate-specific antigen progression in men with localized prostate cancer undergoing active monitoring.

scientific article published on March 2013

Associations of circulating retinol, vitamin E, and 1,25-dihydroxyvitamin D with prostate cancer diagnosis, stage, and grade

scientific article published on 28 August 2012

Associations of folate, vitamin B12, homocysteine, and folate-pathway polymorphisms with prostate-specific antigen velocity in men with localized prostate cancer

scientific article

Associations of lower urinary tract symptoms with prostate-specific antigen levels, and screen-detected localized and advanced prostate cancer: a case-control study nested within the UK population-based ProtecT (Prostate testing for cancer and Treatm

scientific article published on 06 June 2008

Associations of sexual dysfunction symptoms with PSA-detected localised and advanced prostate cancer: a case-control study nested within the UK population-based ProtecT (Prostate testing for cancer and Treatment) study.

scientific article published on 21 June 2009

Associations of vitamin D pathway genes with circulating 25-hydroxyvitamin-D, 1,25-dihydroxyvitamin-D, and prostate cancer: a nested case-control study

scientific article

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

scholarly article published in Nature Genetics

Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry

scientific article published in Nature Communications

Bone morphogenetic protein- and mating-dependent secretory cell growth and migration in the Drosophila accessory gland ⬇️

scientific article published on November 5, 2012

Carotenoids, retinol, tocopherols, and prostate cancer risk: pooled analysis of 15 studies

scientific article

Changes in circulating microRNA levels associated with prostate cancer ⬇️

scientific article published on January 12, 2012

Characteristics of men responding to an invitation to undergo testing for prostate cancer as part of a randomised trial

scientific article published on 13 October 2016

Circulating Folate and Vitamin B12 and Risk of Prostate Cancer: A Collaborative Analysis of Individual Participant Data from Six Cohorts Including 6875 Cases and 8104 Controls

scientific article

Circulating folate, vitamin B12, homocysteine, vitamin B12 transport proteins, and risk of prostate cancer: a case-control study, systematic review, and meta-analysis

scientific article published on 25 May 2010

Circulating insulin-like growth factors and IGF-binding proteins in PSA-detected prostate cancer: the large case-control study ProtecT.

scientific article published on 21 November 2011

Common genetic variants associated with disease from genome-wide association studies are mutually exclusive in prostate cancer and rheumatoid arthritis

scientific article published on 18 September 2012

Common variation in Kallikrein genes KLK5, KLK6, KLK12, and KLK13 and risk of prostate cancer and tumor aggressiveness

article

Contemporary accuracy of death certificates for coding prostate cancer as a cause of death: Is reliance on death certification good enough? A comparison with blinded review by an independent cause of death evaluation committee

scientific article published on 02 June 2016

Continuing controversy over monitoring men with localized prostate cancer: a systematic review of programs in the prostate specific antigen era.

scientific article published on August 2006

Curative radiation therapy in prostate cancer ⬇️

scientific article published on June 1, 2011

Decision-Making about PSA Testing and Prostate Biopsies: A Qualitative Study Embedded in a Primary Care Randomised Trial

scientific article published on 15 August 2007

Detection of prostate cancer in unselected young men: prospective cohort nested within a randomised controlled trial

scientific article

Developing new age-specific prostate-specific antigen thresholds for testing for prostate cancer

scientific article published on 16 February 2018

Development of a complex intervention improved randomization and informed consent in a randomized controlled trial

article

Development of a framework to improve the process of recruitment to randomised controlled trials (RCTs): the SEAR (Screened, Eligible, Approached, Randomised) framework.

scientific article published on 19 January 2018

Development of a new method for monitoring prostate-specific antigen changes in men with localised prostate cancer: a comparison of observational cohorts

scientific article published on 13 March 2009

Differential expression of hMLH1 and hMSH2 is related to bladder cancer grade, stage and prognosis but not microsatellite instability ⬇️

scientific article published on July 1, 2003

Do people who choose their treatment in a large randomised trial with parallel preference groups differ at baseline from those who agree to random treatment allocation? Results from the protect study.

scientific article published on 16 November 2015

Do the risk factors of age, family history of prostate cancer or a higher prostate specific antigen level raise anxiety at prostate biopsy?

scientific article published on 16 April 2009

Effect of a Low-Intensity PSA-Based Screening Intervention on Prostate Cancer Mortality: The CAP Randomized Clinical Trial

scientific article published in The Journal of the American Medical Association

Establishing nurse-led active surveillance for men with localised prostate cancer: development and formative evaluation of a model of care in the ProtecT trial

scientific article

Estimating the sensitivity of a prostate cancer screening programme for different PSA cut-off levels: A UK case study

scientific article published on 23 December 2017

Ethics of clinical trials from bayesian perspective: randomisation to clinical trials may solve dilemma of treatment choice in prostate cancer

scientific article published on June 2003

Evaluating best practice in informed consent discussions: a new method of evaluating information provision and patient understanding during trial recruitment consultations

scientific article published on 29 November 2013

Evaluating genetic risk for prostate cancer among Japanese and Latinos

scientific article

Evaluating the PCPT risk calculator in ten international biopsy cohorts: results from the Prostate Biopsy Collaborative Group.

scientific article published on 31 December 2011

Evaluating the Prostate Cancer Prevention Trial High Grade Prostate Cancer Risk Calculator in 10 international biopsy cohorts: results from the Prostate Biopsy Collaborative Group.

scientific article published on 22 April 2012

Evaluation of association of HNF1B variants with diverse cancers: collaborative analysis of data from 19 genome-wide association studies

scientific article

Evaluation of source data verification in a multicentre cancer trial (PROTECT).

scientific article published on 29 November 2013

Exploring treatment preferences facilitated recruitment to randomized controlled trials

scientific article

Factors distinguishing general practitioners who more readily participated in a large randomized trial were identified

scientific article published on 10 July 2008

Feasibility and cost of obtaining informed consent for essential review of medical records in large-scale health services research.

scientific article published on April 2009

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

scientific article published on 27 March 2013

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.

scientific article

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants.

scientific article published on 11 June 2018

Fine-mapping the HOXB region detects common variants tagging a rare coding allele: evidence for synthetic association in prostate cancer

scientific article

Genetic correction of PSA values using sequence variants associated with PSA levels

scientific article published on December 2010

Genetic variants in the vitamin d receptor are associated with advanced prostate cancer at diagnosis: findings from the prostate testing for cancer and treatment study and a systematic review

scientific article published on 27 October 2009

Genetic variation in prostate-specific antigen-detected prostate cancer and the effect of control selection on genetic association studies

scientific journal article

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Genome-wide association study identifies new prostate cancer susceptibility loci

scientific journal article

Germline variation at 8q24 and prostate cancer risk in men of European ancestry

scientific article published in Nature Communications

Height and prostate cancer risk: a large nested case-control study (ProtecT) and meta-analysis

scientific article published on September 2008

Height, selected genetic markers and prostate cancer risk: results from the PRACTICAL consortium

article by Artitaya Lophatananon et al published 20 March 2018 in British Journal of Cancer

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array

scientific article

Identification of a novel prostate cancer susceptibility variant in the KLK3 gene transcript

scientific article

Identification of new genetic risk factors for prostate cancer

scientific article published on December 2008

Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

scientific article

Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis

scientific article published on 8 January 2015

Importance of prostate volume in the European Randomised Study of Screening for Prostate Cancer (ERSPC) risk calculators: results from the prostate biopsy collaborative group.

scientific article published on 28 December 2011

Incorporating Known Genetic Variants Does Not Improve the Accuracy of PSA Testing to Identify High Risk Prostate Cancer on Biopsy

scientific article published on 2 October 2015

Insertion of an SVA-E retrotransposon into the CASP8 gene is associated with protection against prostate cancer

scientific article published on 5 January 2016

Insulin-like growth factors (IGFs) and IGF-binding proteins in active monitoring of localized prostate cancer: a population-based observational study

scientific article published on 21 October 2012

Investigating the prostate specific antigen, body mass index and age relationship: is an age-BMI-adjusted PSA model clinically useful?

scientific article

It's not just what you say, it's also how you say it: opening the 'black box' of informed consent appointments in randomised controlled trials

Life course sun exposure and risk of prostate cancer: population-based nested case-control study and meta-analysis.

scientific article

Longitudinal prostate-specific antigen reference ranges: Choosing the underlying model of age-related changes

scientific article published on 09 October 2013

Mating induces switch from hormone-dependent to hormone-independent steroid receptor-mediated growth in Drosophila secondary cells

scientific article published on 07 October 2019

Measurement of insulin-like growth factor axis does not enhance specificity of PSA-based prostate cancer screening

Measuring the psychosocial impact of population-based prostate-specific antigen testing for prostate cancer in the UK.

scientific article published in October 2006

Men with prostate cancer make positive dietary changes following diagnosis and treatment.

scientific article published on 22 March 2013

Men's knowledge and attitudes towards dietary prevention of a prostate cancer diagnosis: a qualitative study

scientific article

Metabolic imbalance and prostate cancer progression.

scientific article

Misclassification of outcome in case-control studies: Methods for sensitivity analysis

scientific article published on 12 September 2014

Mortality Among Men with Advanced Prostate Cancer Excluded from the ProtecT Trial

scientific article published on 06 October 2016

Multiple loci on 8q24 associated with prostate cancer susceptibility

scientific article published on 20 September 2009

Multiple loci with different cancer specificities within the 8q24 gene desert

scientific article

Multiple newly identified loci associated with prostate cancer susceptibility

scientific article

Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium

scientific article

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

scientific article published on 29 May 2015

Neural network analysis of combined conventional and experimental prognostic markers in prostate cancer: a pilot study ⬇️

scientific article published on July 1, 1998

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016

PSA-detected prostate cancer and the potential for dedifferentiation--estimating the proportion capable of progression

scientific article published in March 2011

Perceptions of equipoise are crucial to trial participation: a qualitative study of men in the ProtecT study

scientific article published on June 2003

Physical activity, alcohol consumption, BMI and smoking status before and after prostate cancer diagnosis in the ProtecT trial: opportunities for lifestyle modification

scientific article

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

scientific article published on 10 January 2018

Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis.

scientific article

Population-based prostate-specific antigen testing in the UK leads to a stage migration of prostate cancer

scientific article published on 19 June 2009

Post-diagnosis serum insulin-like growth factors in relation to dietary and lifestyle changes in the Prostate testing for cancer and Treatment (ProtecT) trial

scientific article

Predicting high-grade cancer at ten-core prostate biopsy using four kallikrein markers measured in blood in the ProtecT study

scientific article

Prediction of individual genetic risk to prostate cancer using a polygenic score

scientific article published on 14 July 2015

Predictors of 25-hydroxyvitamin D and its association with risk factors for prostate cancer: evidence from the prostate testing for cancer and treatment study

scientific article

Predictors of Attendance for Prostate-Specific Antigen Screening Tests and Prostate Biopsy

scientific article published on 10 January 2012

Prevention and early detection of prostate cancer

scientific article

ProDiet: A Phase II Randomized Placebo-Controlled Trial of Green Tea Catechins and Lycopene in Men at Increased Risk of Prostate Cancer

scientific article published on 11 October 2018

Properties of the 4-Kallikrein Panel Outside the Diagnostic Gray Zone: Meta-Analysis of Patients with Positive Digital Rectal Examination or Prostate Specific Antigen 10 ng/ml and Above

scientific article

Prostate Testing for Cancer and Treatment (ProtecT) feasibility study ⬇️

scientific article published on 01 January 2003

Prostate-cancer mortality in the USA and UK in 1975-2004: an ecological study

scientific article published on 16 April 2008

Prostate-specific antigen (PSA) testing of men in UK general practice: a 10-year longitudinal cohort study

scientific article published on 30 October 2017

Prostate-specific antigen patterns in US and European populations: comparison of six diverse cohorts

scientific article published on 22 January 2016

Prostate-specific antigen testing and prostate biopsy: are self-reported lower urinary tract symptoms and health-related quality of life associated with the decision to undergo these investigations?

article

Prostate-specific antigen testing rates remain low in UK general practice: a cross-sectional study in six English cities.

scientific article published on 11 April 2011

Psychological distress and prostate specific antigen levels in men with and without prostate cancer.

scientific article

Psychological impact of prostate biopsy: physical symptoms, anxiety, and depression

scientific article published on 21 October 2013

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Quality improvement report: Improving design and conduct of randomised trials by embedding them in qualitative research: ProtecT (prostate testing for cancer and treatment) study. Commentary: presenting unbiased information to patients can be diffic

scientific article

Re: Schistosomiasis of the male genital tract: transrectal sonographic findings ⬇️

scientific article published on 01 October 1998

Recruiters to randomised trials can be trained to facilitate recruitment and informed consent by exploring patients’ treatment preferences

scientific article published on 29 November 2013

Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility Loci

scientific article published on 2 April 2015

Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017.

scientific article

Role of information in preparing men for transrectal ultrasound guided prostate biopsy: a qualitative study embedded in the ProtecT trial.

scientific article

Screen-detected prostate cancer and the insulin-like growth factor axis: results of a population-based case-control study

scientific article published on March 2004

Screening for prostate cancer remains controversial

scientific article published on 05 August 2009

Screening for prostate cancer. The case against.

scientific article published on March 2005

Seasonal variation in prostate-specific antigen levels: a large cross-sectional study of men in the UK.

scientific article published on 31 March 2011

Secular trends in prostate cancer mortality, incidence and treatment: England and Wales, 1975-2004.

scientific article published on 10 January 2008

Serum Insulin-Like Growth Factor-I Is Positively Associated with Serum Prostate-Specific Antigen in Middle-Aged Men without Evidence of Prostate Cancer

article

Serum insulin-like growth factors and mortality in localised and advanced clinically detected prostate cancer

scientific article published on 20 December 2011

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

scientific article

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Short term outcomes of prostate biopsy in men tested for cancer by prostate specific antigen: prospective evaluation within ProtecT study.

scientific article published on 9 January 2012

Society for Social Medicine and the International Epidemiological Association European Group. Abstracts of oral presentations

article

Stage shift in PSA-detected prostate cancers - effect modification by Gleason score

scientific article published on January 2009

Standardisation of information submitted to an endpoint committee for cause of death assignment in a cancer screening trial – lessons learnt from CAP (Cluster randomised triAl of PSA testing for Prostate cancer).

scientific article published on 23 January 2015

Systematic Review and Meta-analysis of Factors Determining Change to Radical Treatment in Active Surveillance for Localized Prostate Cancer.

scientific article published on 21 January 2015

The Use of Flow Cytometry and RT-PCR in the Detection of Circulating PSA-Positive Cells in Prostate Cancer

scientific article published on January 1, 1998

The associations of anthropometric, behavioural and sociodemographic factors with circulating concentrations of IGF‐I, IGF‐II, IGFBP‐1, IGFBP‐2 and IGFBP‐3 in a pooled analysis of 16,024 men from 22 studies

scientific article published on 04 April 2019

The case against.

scientific article published on March 2005

The effects of height and BMI on prostate cancer incidence and mortality: a Mendelian randomization study in 20,848 cases and 20,214 controls from the PRACTICAL consortium

scientific article

The importance of dietary change for men diagnosed with and at risk of prostate cancer: a multi-centre interview study with men, their partners and health professionals

scientific article

The relation between adiposity throughout the life course and variation in IGFs and IGFBPs: evidence from the ProtecT (Prostate testing for cancer and Treatment) study

article

The relationship between prostate-specific antigen and prostate cancer risk: the Prostate Biopsy Collaborative Group

scientific article (publication date: September 2010)

Training recruiters to randomized trials to facilitate recruitment and informed consent by exploring patients' treatment preferences

scientific article

Understanding factors influencing questionnaire response rates to maximise retention in a long term complex intervention trial.

scientific article published on 13 December 2011

Using genetic proxies for lifecourse sun exposure to assess the causal relationship of sun exposure with circulating vitamin d and prostate cancer risk

scientific article published on 25 February 2013

Validating the use of Hospital Episode Statistics data and comparison of costing methodologies for economic evaluation: an end-of-life case study from the Cluster randomised triAl of PSA testing for Prostate cancer (CAP).

scientific article

Validation of a modelling approach for estimating the likely effectiveness of cancer screening using cancer data on prevalence screening and incidence.

scientific article

Validation of the Hospital Episode Statistics Outpatient Dataset in England

scientific article published on 19 September 2015

Very low PSA concentrations and deletions of the KLK3 gene

scientific article published on 20 November 2012

Who can best recruit to randomized trials? Randomized trial comparing surgeons and nurses recruiting patients to a trial of treatments for localized prostate cancer (the ProtecT study).

scientific article published in July 2003

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