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List of works by Barbara Bohle

100 years of immunotherapy: the Monaco charter. under the high patronage of His Serene Highness Prince Albert II of Monaco

scientific article published on 21 November 2012

126 Creation of a Humanized Model for Respiratory Allergy Using a Human Mugwort-specificT-Cell Receptor and HLA-DR1.

scientific article published on 17 February 2012

3-Layer-based analysis of peptide-MHC interaction: in silico prediction, peptide binding affinity and T cell activation in a relevant allergen-specific model.

scientific article

4(th) European Congress of Immunology - ECI 2015: Vienna, September 6-9, 2015.

scientific article published in July 2015

4-1BB costimulation promotes bystander activation of human CD8 T cells

scientific article published on 12 November 2020

6th International Symposium on Molecular Allergology (ISMA).

scientific article

A food matrix reduces digestion and absorption of food allergens in vivo

scientific article published on 30 August 2011

A human monoclonal IgE antibody defines a highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5: molecular, immunological, and structural characterization of the epitope-containing domain.

scientific article

A hypoallergenic variant of the major birch pollen allergen shows distinct characteristics in antigen processing and T-cell activation

scientific article published on 13 September 2012

A novel approach to specific allergy treatment: the recombinant allergen-S-layer fusion protein rSbsC-Bet v 1 matures dendritic cells that prime Th0/Th1 and IL-10-producing regulatory T cells

scientific article published on 01 December 2007

A novel approach to specific allergy treatment: the recombinant fusion protein of a bacterial cell surface (S-layer) protein and the major birch pollen allergen Bet v 1 (rSbsC-Bet v 1) combines reduced allergenicity with immunomodulating capacity.

scientific article published on June 2004

A novel role for neutrophils in IgE-mediated allergy: Evidence for antigen presentation in late-phase reactions

scientific article published on 18 June 2018

A recombinant bacterial cell surface (S-layer)-major birch pollen allergen-fusion protein (rSbsC/Bet v1) maintains the ability to self-assemble into regularly structured monomolecular lattices and the functionality of the allergen.

scientific article published in March 2002

A sensitive assay for the detection of IgE bound to the major birch pollen allergen, Bet v 1, in the form of immune complexes

scientific article published on 17 April 2009

AIC. Dynavax

scientific article

Allergen hybrids - next generation vaccines for Fagales pollen immunotherapy

scientific article

Allergen microarray: comparison of microarray using recombinant allergens with conventional diagnostic methods to detect allergen-specific serum immunoglobulin E.

scientific article published on October 2003

Allergen-specific IgE production of committed B cells from allergic patients in vitro

scientific article published on 01 August 1995

Allergen-specific T lymphocytes as targets for specific immunotherapy: striking at the roots of type I allergy.

scientific article

AllergenOnline: A peer-reviewed, curated allergen database to assess novel food proteins for potential cross-reactivity

scientific article published on 17 February 2016

Allergy immunotherapy across the life cycle to promote active and healthy ageing: from research to policies: An AIRWAYS Integrated Care Pathways (ICPs) programme item (Action Plan B3 of the European Innovation Partnership on active and healthy [...]

scientific article

Allergy multivaccines created by DNA shuffling of tree pollen allergens

scientific article published on 10 July 2007

Allergy to millet: another risk for atopic bird keepers

scientific article published on 01 April 2003

Alpha-Gal on bioprostheses: xenograft immune response in cardiac surgery.

scientific article

Alum triggers infiltration of human neutrophils ex vivo and causes lysosomal destabilization and mitochondrial membrane potential-dependent NET-formation

scientific article published on 29 August 2020

Alum-adjuvanted allergoids induce functional IgE-blocking antibodies

scientific article published on 12 February 2018

Amb a 1 isoforms: Unequal siblings with distinct immunological features.

scientific article published on 2 May 2017

Anaphylaxis to buckwheat in an atopic child: a risk factor for severe allergy to nuts and seeds?

scientific article published on 30 March 2011

Antigen presentation of the immunodominant T-cell epitope of the major mugwort pollen allergen, Art v 1, is associated with the expression of HLA-DRB1 *01.

scientific article

Apple allergy across Europe: how allergen sensitization profiles determine the clinical expression of allergies to plant foods

scientific article published on 27 June 2006

Assessing protein immunogenicity with a dendritic cell line-derived endolysosomal degradome

scientific article (publication date: 16 February 2011)

Assessment of Bet v 1-specific CD4+ T cell responses in allergic and nonallergic individuals using MHC class II peptide tetramers

article

Association of HLA-DR1 with the allergic response to the major mugwort pollen allergen: molecular background.

scientific article

B cell-derived exosomes can present allergen peptides and activate allergen-specific T cells to proliferate and produce TH2-like cytokines

scientific article published on 14 September 2007

Bet v 1 and homologous food allergens are similarly processed by antigen-presenting cells but differ in T cell reactivity

Bet v 1, the major birch pollen allergen, and Mal d 1, the major apple allergen, cross-react at the level of allergen-specific T helper cells

scientific article published on 01 October 1998

Bet v 1, the major birch pollen allergen, conjugated to crystalline bacterial cell surface proteins, expands allergen-specific T cells of the Th1/Th0 phenotype in vitro by induction of IL-12.

scientific article published on December 1997

Bet v 1, the major birch pollen allergen, initiates sensitization to Api g 1, the major allergen in celery: evidence at the T cell level

scientific article published on December 2003

Bet v 1--a Trojan horse for small ligands boosting allergic sensitization?

scientific article

Bet v 1-specific T-cell receptor/forkhead box protein 3 transgenic T cells suppress Bet v 1-specific T-cell effector function in an activation-dependent manner.

scientific article published in January 2011

Bet v 1142-156 is the dominant T-cell epitope of the major birch pollen allergen and important for cross-reactivity with Bet v 1-related food allergens

scientific article

Biodegradable PLGA particles for improved systemic and mucosal treatment of Type I allergy.

scientific article

Biomarkers for monitoring clinical efficacy of allergen immunotherapy for allergic rhinoconjunctivitis and allergic asthma: an EAACI Position Paper.

scientific article published on 2 February 2017

Birch pollen allergen-specific immunotherapy with glutaraldehyde-modified allergoid induces IL-10 secretion and protective antibody responses

scientific article published on 11 April 2019

Birch pollen-related food allergy: clinical aspects and the role of allergen-specific IgE and IgG4 antibodies

scientific article published on 20 January 2011

Blocking antibodies induced by allergen-specific immunotherapy ameliorate allergic airway disease in a human/mouse chimeric model.

scientific article published on 21 November 2017

Characterization of HLA class II/peptide-TCR interactions of the immunodominant T cell epitope in Art v 1, the major mugwort pollen allergen.

scientific article published on September 2008

Characterization of T cell responses to Hev b 3, an allergen associated with latex allergy in spina bifida patients.

scientific article

Characterization of autoreactive T cells to the autoantigens heterogeneous nuclear ribonucleoprotein A2 (RA33) and filaggrin in patients with rheumatoid arthritis

scientific article published on 01 July 2002

Characterization of recombinant Mal d 4 and its application for component-resolved diagnosis of apple allergy

scientific article published on August 2006

Characterization of recombinant cat albumin

scientific article published on 01 December 2003

Characterization of the T cell response to the major hazelnut allergen, Cor a 1.04: evidence for a relevant T cell epitope not cross-reactive with homologous pollen allergens.

scientific article published on October 2005

Characterization of the T-cell response to Dau c 1, the Bet v 1-homolog in carrot

scientific article published on 25 May 2016

Characterization of the allergic T-cell response to Pru p 3, the nonspecific lipid transfer protein in peach

scientific article published on 7 April 2009

Characterization of the human T cell response to antigen 5 from Vespula vulgaris (Ves v 5).

scientific article

Characterization of wild-type recombinant Bet v 1a as a candidate vaccine against birch pollen allergy.

scientific article

Component-resolved in vitro diagnosis in carrot allergy: does the use of recombinant carrot allergens improve the reliability of the diagnostic procedure?

scientific article published in July 2005

Conserved sequence motifs of CDR3 loops of TCR specific for two major epitopes of the grass pollen allergen PhI p 1

scientific article published on 01 November 1998

Context matters: T2 polarization resulting from pollen composition and not from protein-intrinsic allergenicity

article

Cooking birch pollen-related food: divergent consequences for IgE- and T cell-mediated reactivity in vitro and in vivo.

scientific article

Correlation of sensitizing capacity and T-cell recognition within the Bet v 1 family.

scientific article

CpG motifs as possible adjuvants for the treatment of allergic diseases.

scientific article

Creation of an engineered APC system to explore and optimize the presentation of immunodominant peptides of major allergens

scientific article

Critical role of mammalian target of rapamycin for IL-10 dendritic cell induction by a flagellin A conjugate in preventing allergic sensitization.

scientific article published on 25 August 2017

Derangement of apoptosis-related lymphocyte homeostasis in systemic sclerosis

scientific article published on 01 December 2000

Differences in the intrinsic immunogenicity and allergenicity of Bet v 1 and related food allergens revealed by site-directed mutagenesis

scientific article

Differential activation of dendritic cells by toll-like receptors causes diverse differentiation of naïve CD4+ T cells from allergic patients.

scientific article published on 3 October 2014

Differential storage of hydroxyethyl starch (HES) in the skin: an immunoelectron-microscopical long-term study.

scientific article published in May 2001

Dramatically decreased T cell responses but persistent IgE upon reduced pollen exposure

scientific article published on 03 August 2019

EAACI Molecular Allergology User's Guide

scientific article

EAACI: A European Declaration on Immunotherapy. Designing the future of allergen specific immunotherapy

scientific article

Efficacy and safety of 4 months of sublingual immunotherapy with recombinant Mal d 1 and Bet v 1 in patients with birch pollen-related apple allergy.

scientific article

Endolysosomal protease susceptibility of Amb a 1 as a determinant of allergenicity

scientific article published on 20 November 2017

Enhanced Pru p 3 IgE-binding activity by selective free fatty acid-interaction.

scientific article

Erratum to: Risk and safety requirements for diagnostic and therapeutic procedures in allergology: World Allergy Organization Statement

scientific article published on 11 January 2017

Expression and Characterization of Functional Recombinant Bet v 1.0101 in the Chloroplast of Chlamydomonas reinhardtii.

scientific article published on 12 May 2017

Expression of a Major Plant Allergen as Membrane-Anchored and Secreted Protein in Human Cells with Preserved T Cell and B Cell Epitopes

article

Expression of an endotoxin-free S-layer/allergen fusion protein in gram-positive Bacillus subtilis 1012 for the potential application as vaccines for immunotherapy of atopic allergy.

scientific article

Factors influencing the allergenicity and adjuvanticity of allergens.

scientific article published on July 2011

FcepsilonRI engagement of Langerhans cell-like dendritic cells and inflammatory dendritic epidermal cell-like dendritic cells induces chemotactic signals and different T-cell phenotypes in vitro

scientific article published in May 2004

Flow cytometric analysis of cytokine expression in short-term allergen-stimulated T cells mirrors the phenotype of proliferating T cells in long-term cultures

scientific article published on 02 July 2011

Fusion proteins of flagellin and the major birch pollen allergen Bet v 1 show enhanced immunogenicity, reduced allergenicity, and intrinsic adjuvanticity

scientific article published on 26 April 2017

Gastrointestinal digestion of Bet v 1-homologous food allergens destroys their mediator-releasing, but not T cell-activating, capacity

scientific article

Genetic restriction of antigen-presentation dictates allergic sensitization and disease in humanized mice

scientific article published on 5 April 2018

Glutathione-S-transferase: a minor allergen in birch pollen due to limited release from hydrated pollen

scientific article

Glutathione-s-transferase is a minor allergen in birch pollen because of restricted release from hydrated pollen grains

scientific article published on 17 March 2014

HLA class II peptide tetramers vs allergen-induced proliferation for identification of allergen-specific CD4 T cells

scientific article published on 28 November 2014

Harmonization of the Genetic Code Effectively Enhances the Recombinant Production of the Major Birch Pollen Allergen Bet v 1

scientific article published on 25 June 2018

Histone deacetylases 1 and 2 restrain CD4+ cytotoxic T lymphocyte differentiation

scientific article published on 27 February 2020

Hom s 4, an IgE-reactive autoantigen belonging to a new subfamily of calcium-binding proteins, can induce Th cell type 1-mediated autoreactivity

scientific article published on July 2005

Human TCR transgenic Bet v 1-specific Th1 cells suppress the effector function of Bet v 1-specific Th2 cells

scientific article published on 9 September 2011

Human Th2 but not Th9 cells release IL-31 in a STAT6/NF-κB-dependent way.

scientific article published on 18 June 2014

Human blood basophils do not act as antigen-presenting cells for the major birch pollen allergen Bet v 1

scientific article published on 20 December 2011

Humoral and Cellular Cross-Reactivity between Amb a 1, the Major Ragweed Pollen Allergen, and Its Mugwort Homolog Art v 6

scientific article published on 28 December 2011

Hydrocortisone enhances total IgE levels--but not the synthesis of allergen-specific IgE--in a monocyte-dependent manner

scientific article published on 01 September 1995

IFN-gamma-enhanced allergen penetration across respiratory epithelium augments allergic inflammation

scientific article

IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA.

scientific article published on January 2004

IgE and allergen-specific immunotherapy-induced IgG4 recognize similar epitopes of Bet v 1, the major allergen of birch pollen.

scientific article published on 22 October 2016

IgE-blocking antibodies following SLIT with recombinant Mal d 1 accord with improved apple allergy

scientific article published on 04 April 2020

IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone.

scientific article published in April 2003

IgE‐cross‐blocking antibodies to <i>Fagales</i> following sublingual immunotherapy with recombinant Bet v 1

scientific article published in 2021

Immunological changes during specific immunotherapy of grass pollen allergy: reduced lymphoproliferative responses to allergen and shift from TH2 to TH1 in T‐cell clones specific for Phi p 1, a major grass pollen allergen ⬇️

scientific article published on September 1, 1997

Immunological differences between insect venom-allergic patients with and without immunotherapy and asymptomatically sensitized subjects.

scientific article published on 23 November 2017

Immunological mechanisms in sublingual immunotherapy

scientific article published on 01 December 2008

Improving diagnostic tests for food allergy with recombinant allergens

scientific article published on March 2004

Initiating yellow jacket venom immunotherapy with a 100-μg dose: A challenge?

scientific article published on 19 September 2018

Interaction of allergens, major histocompatibility complex molecules, and T cell receptors: a 'ménage à trois' that opens new avenues for therapeutic intervention in type I allergy

scientific article published on 29 March 2011

Interleukin-10 inhibits burst-forming unit-erythroid growth by suppression of endogenous granulocyte-macrophage colony-stimulating factor production from T cells

scientific article published on 01 February 1999

Interleukin-10 inhibits spontaneous colony-forming unit-granulocyte-macrophage growth from human peripheral blood mononuclear cells by suppression of endogenous granulocyte-macrophage colony-stimulating factor release.

scientific article published in February 1997

Intranasal treatment with a recombinant hypoallergenic derivative of the major birch pollen allergen Bet v 1 prevents allergic sensitization and airway inflammation in mice.

scientific article

Kinetics, cross-reactivity, and specificity of Bet v 1-specific IgG4 antibodies induced by immunotherapy with birch pollen.

scientific article published on 21 September 2013

Long-lived Th2 clones specific for seasonal and perennial allergens can be detected in blood and skin by their TCR-hypervariable regions

scientific article published on 01 February 1998

Modulation of allergen-specific T-lymphocyte function by virus-like particles decorated with HLA class II molecules

scientific article

Modulation of the allergic immune response in BALB/c mice by subcutaneous injection of high doses of the dominant T cell epitope from the major birch pollen allergen Bet v 1.

scientific article

Molecular and functional analysis of the antigen receptor of Art v 1-specific helper T lymphocytes.

scientific article published on 26 November 2007

Monitoring the epitope recognition profiles of IgE, IgG 1 , and IgG 4 during birch pollen immunotherapy

scientific article published on 10 December 2015

Mutational analysis of amino acid positions crucial for IgE-binding epitopes of the major apple (Malus domestica) allergen, Mal d 1.

scientific article published on 15 November 2005

NSG mice humanized with allergen-specific T-cell lines as in vivo model of respiratory allergy

scientific article published on 07 March 2020

Natural and recombinant molecules of the cherry allergen Pru av 2 show diverse structural and B cell characteristics but similar T cell reactivity.

scientific article

Natural self-assembly of allergen-S-layer fusion proteins is no prerequisite for reduced allergenicity and T cell stimulatory capacity.

scientific article

Naturally processed T cell-activating peptides of the major birch pollen allergen.

scientific article

Neutrophils promote T-cell-mediated inflammation in allergy

scientific article published on 19 December 2018

Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells

scientific article (publication date: 2012)

Oligodeoxynucleotides containing CpG motifs induce IL-12, IL-18 and IFN-gamma production in cells from allergic individuals and inhibit IgE synthesis in vitro

scientific article published on 01 July 1999

Oligodeoxynucleotides containing CpG motifs induce low levels of TNF-alpha in human B lymphocytes: possible adjuvants for Th1 responses.

scientific article published in March 2001

Oligodeoxynucleotides containing CpG motifs modulate the allergic TH2 response of BALB/c mice to Bet v 1, the major birch pollen allergen.

scientific article

Oral exposure to Mal d 1 affects the immune response in patients with birch pollen allergy

scientific article published on 24 August 2012

Peptide mimotopes displayed by phage inhibit antibody binding to bet v 1, the major birch pollen allergen, and induce specific IgG response in mice.

scientific article

Persistent pruritus after hydroxyethyl starch infusion therapy: a result of long-term storage in cutaneous nerves

scientific article published on 01 April 1997

Prevention of birch pollen-related food allergy by mucosal treatment with multi-allergen-chimers in mice

scientific article

Profiling of human CD4+ T-cell subsets identifies the TH2-specific noncoding RNA GATA3-AS1.

scientific article published on 16 July 2013

Protection against invasive amebiasis by a single monoclonal antibody directed against a lipophosphoglycan antigen localized on the surface of Entamoeba histolytica

scientific article

Protein unfolding strongly modulates the allergenicity and immunogenicity of Pru p 3, the major peach allergen

Proteomic profiling of the weed feverfew, a neglected pollen allergen source.

scientific article published on 20 July 2017

Pru p 3, the nonspecific lipid transfer protein from peach, dominates the immune response to its homolog in hazelnut

scientific article published on 26 February 2011

Recombinant Mal d 1 facilitates sublingual challenge tests of birch pollen-allergic patients with apple allergy.

scientific article

Recombinant Mal d 1 is a reliable diagnostic tool for birch pollen allergen-associated apple allergy

scientific article published on 28 June 2013

Recommendations for the allergy management in the primary care.

scientific article published on 15 March 2014

Regulation of cytokine production in human peripheral blood mononuclear cells and allergen-specific th cell clones by 1alpha,25-dihydroxyvitamin D3.

scientific article published in May 2002

Reshaping the Bet v 1 fold modulates T(H) polarization.

scientific article published on 21 March 2011

Risk and safety requirements for diagnostic and therapeutic procedures in allergology: World Allergy Organization Statement

scientific article

Sclerostin serum levels correlate positively with bone mineral density and microarchitecture in haemodialysis patients

scientific article published on 25 May 2011

Similar Allergenicity to Different Artemisia Species Is a Consequence of Highly Cross-Reactive Art v 1-Like Molecules

scientific article published on 20 August 2019

Structural and immunological characterization of the N-glycans from the major yellow jacket allergen Ves v 2: the N-glycan structures are needed for the human antibody recognition.

scientific article

Sublingual immunotherapy induces IL-10-producing T regulatory cells, allergen-specific T-cell tolerance, and immune deviation

scientific article published on 06 August 2007

Sublingual immunotherapy with recombinant Mal d 1 downregulates the allergen-specific Th2 response

scientific article published on 10 April 2019

Successful sublingual immunotherapy with birch pollen has limited effects on concomitant food allergy to apple and the immune response to the Bet v 1 homolog Mal d 1.

scientific article published on 3 January 2007

Suppression of antigen-specific T- and B-cell responses by intranasal or oral administration of recombinant bet v 1, the major birch pollen allergen, in a murine model of type I allergy

scientific article published on 01 June 1999

Surface LAMP-2 Is an Endocytic Receptor That Diverts Antigen Internalized by Human Dendritic Cells into Highly Immunogenic Exosomes.

scientific article

Systemic immunological changes induced by administration of grass pollen allergens via the oral mucosa during sublingual immunotherapy

scientific article published on 01 November 1999

T Cell Epitope-Containing Domains of Ragweed Amb a 1 and Mugwort Art v 6 Modulate Immunologic Responses in Humans and Mice

scientific article

T cell responses during allergen-specific immunotherapy of Type I allergy.

scientific article published on May 2008

T lymphocytes and food allergy

scientific article published in November 2004

T-cell epitopes of food allergens.

scientific article

T-cell-derived cytokines enhance the antigen-presenting capacity of human neutrophils

scientific article published on 06 August 2019

TGF-beta1 impairs homocysteine metabolism in human renal cells: possible implications for transplantation

scientific article published in August 2003

Tackling Bet v 1 and associated food allergies with a single hybrid protein.

scientific article published on 6 December 2016

Targeting antigens to murine and human M-cells with Aleuria aurantia lectin-functionalized microparticles.

scientific article published in September 2005

Targeting the cysteine-stabilized fold of Art v 1 for immunotherapy of Artemisia pollen allergy

scientific article published in March 2010

The Effect of Birch Pollen Immunotherapy on Apple and rMal d 1 Challenges in Adults with Apple Allergy

scientific article published on 18 February 2020

The IgE-reactive autoantigen Hom s 2 induces damage of respiratory epithelial cells and keratinocytes via induction of IFN-gamma.

scientific article published on 13 December 2007

The T cell response to Art v 1, the major mugwort pollen allergen, is dominated by one epitope.

scientific article published on November 2002

The T-cell response to Amb a 1 is characterized by 3 dominant epitopes and multiple MHC restriction elements

scientific article published on 16 July 2010

The alpha and beta subchain of Amb a 1, the major ragweed-pollen allergen show divergent reactivity at the IgE and T-cell level.

scientific article published on 9 March 2009

The diversity of Bet v 1–specific IgG 4 antibodies remains mostly constant during the course of birch pollen immunotherapy

scientific article published on 02 July 2015

The immunological relationship of epitopes on major tree pollen allergens.

scientific article published in August 1991

The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101.

scientific article

The impact of pollen-related food allergens on pollen allergy.

scientific article published on January 2007

The quantity and quality of α-gal-specific antibodies differ in individuals with and without delayed red meat allergy

scientific article published on 04 June 2016

The role of IgG1 and IgG4 as dominant IgE-blocking antibodies shifts during allergen immunotherapy

scientific article published in 2023

The soluble isoform of human FcɛRI is an endogenous inhibitor of IgE-mediated mast cell responses

scientific article published on 20 November 2018

Toll-like receptor ligands as adjuvants in allergy vaccines

Toll-like receptors as targets for enhancing the efficacy of immunotherapy

scientific article published on 01 January 2009

Tropomyosins in mosquito and house dust mite cross-react at the humoral and cellular level

scientific article published on 14 August 2018

Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S.

scientific article

Who is who in the journal

scientific article published on January 2013

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