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List of works by Ayşe Demirkan

11β-hydroxysteroid dehydrogenase type 1 gene expression is increased in ascending aorta tissue of metabolic syndrome patients with coronary artery disease

scientific article published on 31 August 2012

A Combined Linkage and Exome Sequencing Analysis for Electrocardiogram Parameters in the Erasmus Rucphen Family Study

scientific article published on 8 November 2016

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A combined linkage, microarray and exome analysis suggests MAP3K11 as a candidate gene for left ventricular hypertrophy

scientific article published on 5 March 2018

A genome-wide association study of depressive symptoms

scientific journal article

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

scientific article published on 20 August 2019

Adipose tissue gene expression of adiponectin, tumor necrosis factor-α and leptin in metabolic syndrome patients with coronary artery disease

scientific article published on 15 April 2011

An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype

scientific article published on 8 December 2016

An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis.

scientific article published on 13 June 2019

Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts

scientific article published on 28 February 2018

Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles

scientific article (publication date: 9 December 2013)

Blood-based metabolic signatures in Alzheimer's disease

scientific article published on 6 September 2017

CDH6 and HAGH protein levels in plasma associate with Alzheimer's disease in APOE ε4 carriers

scientific article published on 19 May 2020

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants in Mendelian kidney disease genes and their association with renal function

scientific article published on 12 September 2013

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Corrigendum: Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

scientific article published on 30 March 2015

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Effects of metformin on metabolite profiles and LDL cholesterol in patients with type 2 diabetes

scientific article published on 5 August 2015

Erratum: Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms

article

Evaluation of glutathione S-transferase P1 polymorphisms (Ile105Val and Ala114Val) in patients with small cell lung cancer.

scientific article published on 17 February 2012

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 06 June 2019

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

scientific article published on 01 September 2019

Exome-sequencing in a large population-based study reveals a rare Asn396Ser variant in the LIPG gene associated with depressive symptoms.

scientific article published on 19 July 2016

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Genetic architecture of circulating lipid levels

scientific article

Genetic architecture of open angle glaucoma and related determinants

scientific article published on 7 November 2010

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

scientific article

Genetic determinants of circulating sphingolipid concentrations in European populations

scientific article published on 02 October 2009

Genetic risk profiles for depression and anxiety in adult and elderly cohorts

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants in RBFOX3 are associated with sleep latency

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association and functional follow-up reveals new loci for kidney function

scientific article

Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels

scientific article

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations

scientific article

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

scientific article published on February 2016

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide profiling of blood pressure in adults and children

scientific article published on 27 December 2011

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.

scientific article published on 23 March 2016

Glutathione S-transferase P1 polymorphisms are associated with time to tumor progression in small cell lung cancer patients

scientific article published on 01 April 2011

Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration

article published in 2019

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

scientific article published on 13 January 2020

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

scientific article published on 8 September 2012

Investigation of the possible association of NEDD4-2 (NEDD4L) gene with idiopathic photosensitive epilepsy

scientific article published on 27 December 2014

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

scientific article published on 12 July 2017

Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization

scientific article published in 2023

Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine

scientific article published on 03 April 2019

Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels

scientific article published in Nature Communications

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology

scientific article published on 28 January 2015

Metabolic network failures in Alzheimer's disease: A biochemical road map.

scientific article published on 21 March 2017

Metabolic profiling of intra- and extracranial carotid artery atherosclerosis

scientific article published on 08 March 2018

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

scientific article published on 12 August 2019

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

scientific article published on 21 November 2016

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

scientific article published on February 2016

Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis

scientific article

Plasma phosphatidylcholine and sphingomyelin concentrations are associated with depression and anxiety symptoms in a Dutch family-based lipidomics study

scientific article published on 30 November 2012

Presence of fatty-acid-binding protein 4 expression in human epicardial adipose tissue in metabolic syndrome.

scientific article

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

Seroreactivity against PTEN-induced putative kinase 1 (PINK1) in Turkish patients with Behçet's disease.

scientific article

Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies

scientific article

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

scientific article published on 02 October 2019

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The neuronal transporter gene SLC6A15 confers risk to major depression

scientific article

Tumor necrosis factor alpha, interleukin-6 and interleukin-10 polymorphisms in preeclampsia

scientific article published in February 2010

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