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List of works by Fabrizio Tagliavini

A 52-Year-Old Man with Myoclonic Jerks

scientific article published in March 2016

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers

A Case of Dementia Parkinsonism Resembling Progressive Supranuclear Palsy Due to Mutation in the Tau Protein Gene ⬇️

scientific article published on October 1, 2003

A New Face for Old Antibiotics: Tetracyclines in Treatment of Amyloidoses ⬇️

scientific article published on May 8, 2013

A case of multiple sclerosis with pure, massive superficial demyelination.

scientific article published on 11 July 2012

A case of progressive frontal lobe syndrome in a sporadic form of Cerebral Amyloid Angiopathy: A singular overlap with fronto-temporal dementia?

scientific article published on 28 August 2015

A cluster of progranulin C157KfsX97 mutations in Southern Italy: clinical characterization and genetic correlations.

scientific article published on 11 October 2016

A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia

scientific article

A mutation in the 5'-UTR of GRN gene associated with frontotemporal lobar degeneration: phenotypic variability and possible pathogenetic mechanisms

scientific article published on January 2014

A new function of microtubule-associated protein tau: involvement in chromosome stability

scientific article published on 25 June 2008

A novel Italian presenilin 2 gene mutation with prevalent behavioral phenotype.

scientific article published in January 2009

A novel pathogenic PSEN1 mutation in a family with Alzheimer's disease: phenotypical and neuropathological features.

scientific article published in January 2011

A novel phenotype of sporadic Creutzfeldt-Jakob disease

scientific article published on 02 February 2009

A novel phenotype of sporadic Creutzfeldt-Jakob disease.

scientific article

A novel progranulin mutation causing frontotemporal lobar degeneration with heterogeneous phenotypic expression.

scientific article published in January 2011

A progranulin mutation associated with cortico-basal syndrome in an Italian family expressing different phenotypes of fronto-temporal lobar degeneration ⬇️

scientific article published on June 22, 2011

A promising rating scale for prion disease clinical research ⬇️

scientific article published on June 11, 2013

A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis.

scientific article published on March 2009

A soluble form of prion protein in human cerebrospinal fluid: implications for prion-related encephalopathies

scientific article published on May 15, 1992

APP mutations in the Aβ coding region are associated with abundant cerebral deposition of Aβ38.

scientific article

Adult metachromatic leucodystrophy: clinicopathological report of two familial cases with slow course ⬇️

scientific article published on May 1, 1979

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

scientific article published on 10 December 2015

Alzheimer neuropathology without frontotemporal lobar degeneration hallmarks (TAR DNA-binding protein 43 inclusions) in missense progranulin mutation Cys139Arg

scientific article published on 20 December 2016

Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58 ⬇️

scientific article published on March 1, 1991

An APOE haplotype associated with decreased ε4 expression increases the risk of late onset Alzheimer's disease

scientific article published in January 2011

An In Vivo (11)C-(R)-PK11195 PET and In Vitro Pathology Study of Microglia Activation in Creutzfeldt-Jakob Disease.

scientific article

An antibody raised against a conserved sequence of the prion protein recognizes pathological isoforms in human and animal prion diseases, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy ⬇️

scientific article published on June 1, 1998

Analysis of Conformational Stability of Abnormal Prion Protein Aggregates across the Spectrum of Creutzfeldt-Jakob Disease Prions

scientific article

Anti-A autoantibodies in the CSF of a patient with CAA-related inflammation: A case report

scientific article published on 01 March 2011

Atypical frontotemporal dementia as a new clinical phenotype of Gerstmann-Straussler-Scheinker disease with the PrP-P102L mutation. Description of a previously unreported Italian family

scientific article

Atypical presentation of Creutzfeldt-Jakob disease: the first Italian case associated with E196K mutation in the PRNP gene.

scientific article published on 15 August 2008

Atypical tauopathy with massive involvement of the white matter

scientific article published on 15 January 2008

Brain delivery of AAV9 expressing an anti-PrP monovalent antibody delays prion disease in mice.

scientific article

C9ORF72 Hexanucleotide Repeat Number in Frontotemporal Lobar Degeneration: A Genotype-Phenotype Correlation Study

scientific article published on 01 January 2015

C9ORF72 hexanucleotide repeat number in frontotemporal lobar degeneration: a genotype-phenotype correlation study

scientific article published in January 2014

C9orf72, AAO and ancestry help discriminating behavioural from language variants in FTLD cohorts

scientific article published on 17 September 2020

Cerebrospinal fluid real-time quaking-induced conversion is a robust and reliable test for sporadic creutzfeldt-jakob disease: An international study

scientific article published on 30 April 2016

Characterization of Amyloid-β Deposits in Bovine Brains

scientific article

Chronic wasting disease and atypical forms of bovine spongiform encephalopathy and scrapie are not transmissible to mice expressing wild-type levels of human prion protein.

scientific article published on 11 April 2012

Clinical and neuropathological phenotype associated with the novel V189I mutation in the prion protein gene

article

Clinical neuropathology of Creutzfeldt-Jakob disease

scientific article published on May 1, 1997

Clinical trials

scientific article published on 01 January 2018

Clinical trials of prion disease therapeutics

scientific article published on 01 February 2019

Cognitive deficits in familial Alzheimer's disease associated with M239V mutation of presenilin 2.

scientific article published on 10 August 2006

Cognitive reserve and TMEM106B genotype modulate brain damage in presymptomatic frontotemporal dementia: a GENFI study

scientific article

Combining drug and music therapy in patients with moderate Alzheimer's disease: a randomized study

scientific article published on 17 March 2018

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

scientific article published on 7 June 2021

Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI).

scientific article

Complexes of amyloid-beta and cystatin C in the human central nervous system

scientific article published on January 2009

Consensus classification of human prion disease histotypes allows reliable identification of molecular subtypes: an inter-rater study among surveillance centres in Europe and USA

scientific article published on 30 June 2012

Conversion of the BASE prion strain into the BSE strain: the origin of BSE?

scientific article

Creutzfeldt-Jakob disease with a novel extra-repeat insertional mutation in the PRNP gene.

scientific article published in November 2003

Deep Learning Representation from Electroencephalography of Early-Stage Creutzfeldt-Jakob Disease and Features for Differentiation from Rapidly Progressive Dementia.

scientific article published on 3 May 2016

Defined α-synuclein prion-like molecular assemblies spreading in cell culture

scientific article

Detection of misfolded Aβ oligomers for sensitive biochemical diagnosis of Alzheimer's disease

scientific article published on 20 March 2014

Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia

scientific article

Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease

scientific article published on December 2016

Diagnostic differentiation of mild cognitive impairment due to Alzheimer's disease using a hippocampus-dependent test of spatial memory.

scientific article published on 26 March 2015

Different mutations at V363 MAPT codon are associated with atypical clinical phenotypes and show unusual structural and functional features.

scientific article published on 7 September 2013

Differential overexpression of SERPINA3 in human prion diseases

scientific article published on 15 November 2017

Distinct Neuroanatomical Correlates of Neuropsychiatric Symptoms in the Three Main Forms of Genetic Frontotemporal Dementia in the GENFI Cohort

scientific article published on 01 January 2018

Distinct patterns of brain atrophy in Genetic Frontotemporal Dementia Initiative (GENFI) cohort revealed by visual rating scales.

scientific article

Divergent cognitive status with the same Braak stage of neurofibrillary pathology: does the pattern of amyloid-β deposits make the difference?

scientific article published on 01 January 2015

Doxycycline in Creutzfeldt-Jakob disease: a phase 2, randomised, double-blind, placebo-controlled trial.

scientific article published on 8 January 2014

Effects of Multiple Genetic Loci on Age at Onset in Frontotemporal Dementia.

scientific article published on 23 January 2017

Effects of peptidyl-prolyl isomerase 1 depletion in animal models of prion diseases.

scientific article published in March 2018

Expression of A2V-mutated Aβ in Caenorhabditis elegans results in oligomer formation and toxicity

scientific article

FVEPs in Creutzfeldt–Jacob disease: waveforms and interaction with the periodic EEG pattern assessed by single sweep analysis

scientific article published on 13 January 2005

Failure to replicate an association of rs5984894 SNP in the PCDH11X gene in a collection of 1,222 Alzheimer's disease affected patients

scientific article

Familial frontotemporal dementia associated with the novel MAPT mutation T427M.

scientific article published on 6 June 2005

Frontotemporal dementia and its subtypes: a genome-wide association study

scientific article

Frontotemporal lobar degeneration: old knowledge and new insight into the pathogenetic mechanisms of tau mutations

scientific article

Genetic Counseling and Testing for Alzheimer's Disease and Frontotemporal Lobar Degeneration: An Italian Consensus Protocol.

scientific article

Good gene, bad gene: new APP variant may be both

scientific article published on 19 June 2012

Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases

scientific article published on 22 January 2018

Hereditary and sporadic beta-amyloidoses ⬇️

scientific article published on June 1, 2013

Hereditary cerebral hemorrhage with amyloidosis associated with the E693K mutation of APP.

scientific article published on August 2010

Hereditary prion protein amyloidoses ⬇️

scientific article published on March 1, 2003

Iatrogenic Creutzfeldt-Jakob disease with Amyloid-β pathology: an international study

scientific article published on 8 January 2018

Idiopathic progressive chorea: misnomer or still reality? A case with neuropathological disconfirmation

scientific article published on 17 March 2014

In Situ Tissue Labeling of Cerebral Amyloid Using HIV-Related Tat Peptide

scientific article published on 19 January 2018

Infectivity in skeletal muscle of cattle with atypical bovine spongiform encephalopathy.

scientific article

Inter-laboratory assessment of PrPSc typing in creutzfeldt-jakob disease: a Western blot study within the NeuroPrion Consortium

scientific article published on 2 July 2008

Inter-laboratory comparison of neuropathological assessments of β-amyloid protein: a study of the BrainNet Europe consortium

scientific article published on 15 March 2008

Intracranial and spinal dermo-epidermoid tumours. Anatomoclinical study (author's transl)

scientific article published on 01 January 1978

Intraspecies transmission of BASE induces clinical dullness and amyotrophic changes

scientific article

Italian Frontotemporal Dementia Network (FTD Group-SINDEM): sharing clinical and diagnostic procedures in Frontotemporal Dementia in Italy.

scientific article published on 21 December 2014

Lewy body pathology and typical Parkinson disease in a patient with a heterozygous (R275W) mutation in the Parkin gene (PARK2)

scientific article published on 04 May 2012

Loss of exosomes in progranulin-associated frontotemporal dementia

scientific article published on 7 January 2016

Low-dose CT for the spatial normalization of PET images: A validation procedure for amyloid-PET semi-quantification

scientific article published on 19 July 2018

Lower limb areflexia without central and peripheral conduction abnormalities is highly suggestive of Gerstmann–Sträussler–Scheinker disease Pro102Leu

scientific article published on 16 December 2010

MM2-thalamic Creutzfeldt-Jakob disease: neuropathological, biochemical and transmission studies identify a distinctive prion strain.

scientific article published on 21 February 2012

MRI abnormalities found 1 year prior to symptom onset in a case of Creutzfeldt-Jakob disease

scientific article published on 12 February 2016

Mathematical models for the diffusion magnetic resonance signal abnormality in patients with prion diseases.

scientific article

Measles Inclusion-Body Encephalitis: Neuronal Phosphorylated Tau Protein is Present in the Biopsy but not in the Autoptic Specimens of the Same Patient

scientific article published on 14 October 2015

Measles Inclusion-Body Encephalitis: Neuronal Phosphorylated Tau Protein is Present in the Biopsy but not in the Autoptic Specimens of the Same Patient.

scientific article published on 4 April 2016

Mirror Image of the Amyloid-β Species in Cerebrospinal Fluid and Cerebral Amyloid in Alzheimer's Disease

scientific article published in August 2015

Missense mutation in GRN gene affecting RNA splicing and plasma progranulin level in a family affected by frontotemporal lobar degeneration.

scientific article published on 20 February 2017

Missense mutations in progranulin gene associated with frontotemporal lobar degeneration: study of pathogenetic features

scientific article published on 2 November 2015

Molecular subtypes of Alzheimer's disease.

scientific article published on 19 February 2018

Mutant presenilin 1 increases the expression and activity of BACE1

scientific article published on 05 February 2009

Mutant prion protein expression causes motor and memory deficits and abnormal sleep patterns in a transgenic mouse model.

scientific article published in November 2008

Mutations in MAPT give rise to aneuploidy in animal models of tauopathy

scientific article

Myoclonus in Creutzfeldt-Jakob disease: Polygraphic and video-electroencephalography assessment of 109 patients

scientific article published on 01 December 2010

Neocortical variation of Abeta load in fully expressed, pure Alzheimer's disease.

scientific article published in January 2010

Neuronal counts in basal nucleus of Meynert in Alzheimer disease and in simple senile dementia ⬇️

scientific article published on February 26, 1983

Neuropathological and clinical phenotype of an Italian Alzheimer family with M239V mutation of presenilin 2 gene.

scientific article published in March 2004

Neuropathology of the recessive A673V APP mutation: Alzheimer disease with distinctive features.

scientific article published on 15 September 2010

Neurotoxic and gliotrophic activity of a synthetic peptide homologous to Gerstmann-Sträussler-Scheinker disease amyloid protein.

scientific article published in February 2007

New mutations in MAPT gene causing frontotemporal lobar degeneration: biochemical and structural characterization.

scientific article published on 22 September 2011

Normal Pressure Hydrocephalus and Parkinsonism: Preliminary Data on Neurosurgical and Neurological Treatment.

scientific article

Note on the pathology of the basal nucleus of Meynert in degenerative brain disorders

scientific article published on January 1, 1984

Novel PSEN1 mutations (H214N and R220P) associated with familial Alzheimer's disease identified by targeted exome sequencing

scientific article

Optimal plasma progranulin cutoff value for predicting null progranulin mutations in neurodegenerative diseases: a multicenter Italian study

scientific article published on 26 November 2011

Oxidative damage to nucleic acids in human prion disease

scientific article published in April 2002

Panencephalopathic Creutzfeldt-Jakob disease with distinct pattern of prion protein deposition in a patient with D178N mutation and homozygosity for valine at codon 129 of the prion protein Gene.

scientific article

Pathogenic Aβ A2V versus protective Aβ A2T mutation: Early stage aggregation and membrane interaction

scientific article

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

scientific article published on 26 November 2020

Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody.

scientific article published on 28 July 2006

Patterns of gray matter atrophy in genetic frontotemporal dementia: results from the GENFI study

scientific article published on 19 October 2017

Periodic electroencephalogram complexes in a patient with variant Creutzfeldt-Jakob disease

scientific article published on 01 February 2006

Polyanion induced fibril growth enables the development of a reproducible assay in solution for the screening of fibril interfering compounds, and the investigation of the prion nucleation site

article

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

scientific article

Pre-symptomatic detection of prions by cyclic amplification of protein misfolding.

scientific article published in January 2005

Preamyloid Deposits, Amyloid Deposits, and Senile Plaques in Alzheimer's Disease, Down Syndrome, and Aging ⬇️

scientific article published on January 1, 1991

Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis.

scientific article published on 4 February 2015

Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross-sectional diffusion tensor imaging study

scientific article published on 11 July 2018

Preventive study in subjects at risk of fatal familial insomnia: Innovative approach to rare diseases

scientific article

Prion deposition in olfactory biopsy of sporadic Creutzfeldt-Jakob disease

scientific article published on 01 February 2004

Prions Strongly Reduce NMDA Receptor S-Nitrosylation Levels at Pre-symptomatic and Terminal Stages of Prion Diseases

scientific article published on 01 February 2019

Prions in the urine of patients with variant Creutzfeldt-Jakob disease

scientific article

Prodromal Alzheimer's disease presenting as cerebral amyloid angiopathy-related inflammation with spontaneous amyloid-related imaging abnormalities and high cerebrospinal fluid anti-Aβ autoantibodies.

scientific article

Progranulin plasma levels predict the presence of GRN mutations in asymptomatic subjects and do not correlate with brain atrophy: results from the GENFI study

scientific article published on 13 November 2017

Recurrent generalized seizures, visual loss, and palinopsia as phenotypic features of neuronal ceroid lipofuscinosis due to progranulin gene mutation

article

Redox metals and oxidative abnormalities in human prion diseases

scientific article published on 11 August 2005

Regression of chronic posterior leukoencephalopathy after stop of methotrexate treatment.

scientific article published on 21 July 2009

Review: PrP 106-126 - 25 years after

scientific article published on 03 February 2019

Role of plasminogen in propagation of scrapie

scientific article

Severe microcephaly with polynodular heterotopia: a high-field MRI and neuropathological case study

scientific article published on 01 June 2013

Sneddon's syndrome and renal carcinoma. Case report

scientific article published on September 1, 1992

Spatiotemporal analysis for detection of pre-symptomatic shape changes in neurodegenerative diseases: Initial application to the GENFI cohort

Sporadic Creutzfeldt-Jakob Disease

Sporadic Creutzfeldt-Jakob disease: the extent of microglia activation is dependent on the biochemical type of PrPSc

scientific article published on 01 October 2005

Sporadic human prion diseases: molecular insights and diagnosis ⬇️

scientific article published on July 1, 2012

Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium

scientific article published on 26 March 2008

Stereotypic behaviors in degenerative dementias.

scientific article published on 31 May 2012

Structural properties of Gerstmann-Straussler-Scheinker disease amyloid protein.

scientific article published on 11 September 2003

Synthetic Prion Selection and Adaptation

scientific article published on 03 August 2018

Synthetic prions with novel strain-specified properties

scientific article

Tackling amyloidogenesis in Alzheimer's disease with A2V variants of Amyloid-β.

scientific article published on 11 February 2016

Tau Mutations Serve as a Novel Risk Factor for Cancer

scientific article published on 24 May 2018

Tau Mutations as a Novel Risk Factor for Cancer-Response

scientific article published on 29 October 2018

Temporal necrotizing encephalitis with a subacute course; a clinical and anatomical case

scientific article published on 01 January 1979

Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction.

scientific article

Tetracyclines and prion infectivity.

scientific article

The A2V mutation as a new tool for hindering Aβ aggregation: A neutron and x-ray diffraction study

scientific article published on 14 July 2017

The behavioural features of fatal familial insomnia: A new Italian case with pathological verification

scientific article published on 27 September 2008

The cell-permeable Aβ1-6A2VTAT(D) peptide reverts synaptopathy induced by Aβ1-42wt

scientific article

The contribution of the amyloid hypothesis to the understanding of Alzheimer's disease: a critical overview.

scientific article

The efficacy of tetracyclines in peripheral and intracerebral prion infection.

scientific article

The epsilon isoform of 14-3-3 protein is a component of the prion protein amyloid deposits of Gerstmann-Sträussler-Scheinker disease.

scientific article published in February 2007

The inner fluctuations of the brain in presymptomatic Frontotemporal Dementia: The chronnectome fingerprint

scientific article published on 01 February 2019

The new β amyloid-derived peptide Aβ1-6A2V-TAT(D) prevents Aβ oligomer formation and protects transgenic C. elegans from Aβ toxicity.

scientific article published on 11 January 2016

The peculiar role of the A2V mutation in amyloid-β (Aβ) 1-42 molecular assembly

scientific article

The semantic variant of primary progressive aphasia: clinical and neuroimaging evidence in single subjects

scientific article

Therapeutic approaches to prion diseases.

scientific article

Towards an early clinical diagnosis of sporadic CJD VV2 (ataxic type).

scientific article

Transgenic fatal familial insomnia mice indicate prion infectivity-independent mechanisms of pathogenesis and phenotypic expression of disease

scientific article

Translational Research in Alzheimer's and Prion Diseases

scientific article published on 20 November 2017

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

scientific article published in Nature Communications

V363I and V363A mutated tau affect aggregation and neuronal dysfunction differently in C. elegans

scientific article published on 22 June 2018

Variability of the clinical phenotype in an Italian family with dementia associated with an intronic deletion in the GRN gene.

scientific article

Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein.

scientific article

White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort

scientific article

α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication.

scientific article published on 30 August 2017

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