List of works - Fabrizio Tagliavini

APP mutations in the Aβ coding region are associated with abundant cerebral deposition of Aβ38.

scientific article

α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication.

scientific article published on 30 August 2017

Tetracyclines and prion infectivity.

scientific article

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

scientific article published in Nature Communications

The semantic variant of primary progressive aphasia: clinical and neuroimaging evidence in single subjects

scientific article

Expression of A2V-mutated Aβ in Caenorhabditis elegans results in oligomer formation and toxicity

scientific article

An APOE haplotype associated with decreased ε4 expression increases the risk of late onset Alzheimer's disease

scientific article published in January 2011

C9ORF72 hexanucleotide repeat number in frontotemporal lobar degeneration: a genotype-phenotype correlation study

scientific article published in January 2014

Neurotoxic and gliotrophic activity of a synthetic peptide homologous to Gerstmann-Sträussler-Scheinker disease amyloid protein.

scientific article published in February 2007

Preventive study in subjects at risk of fatal familial insomnia: Innovative approach to rare diseases

scientific article

A novel Italian presenilin 2 gene mutation with prevalent behavioral phenotype.

scientific article published in January 2009

Diagnostic differentiation of mild cognitive impairment due to Alzheimer's disease using a hippocampus-dependent test of spatial memory.

scientific article published on 26 March 2015

Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia

scientific article

Recurrent generalized seizures, visual loss, and palinopsia as phenotypic features of neuronal ceroid lipofuscinosis due to progranulin gene mutation

article

Brain delivery of AAV9 expressing an anti-PrP monovalent antibody delays prion disease in mice.

scientific article

White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort

scientific article

Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody.

scientific article published on 28 July 2006

Good gene, bad gene: new APP variant may be both

scientific article published on 19 June 2012

Mutations in MAPT give rise to aneuploidy in animal models of tauopathy

scientific article

Cognitive reserve and TMEM106B genotype modulate brain damage in presymptomatic frontotemporal dementia: a GENFI study

scientific article

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

scientific article

Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI).

scientific article

Analysis of Conformational Stability of Abnormal Prion Protein Aggregates across the Spectrum of Creutzfeldt-Jakob Disease Prions

scientific article

Prodromal Alzheimer's disease presenting as cerebral amyloid angiopathy-related inflammation with spontaneous amyloid-related imaging abnormalities and high cerebrospinal fluid anti-Aβ autoantibodies.

scientific article

Tackling amyloidogenesis in Alzheimer's disease with A2V variants of Amyloid-β.

scientific article published on 11 February 2016

Atypical presentation of Creutzfeldt-Jakob disease: the first Italian case associated with E196K mutation in the PRNP gene.

scientific article published on 15 August 2008

Frontotemporal lobar degeneration: old knowledge and new insight into the pathogenetic mechanisms of tau mutations

scientific article

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers

Different mutations at V363 MAPT codon are associated with atypical clinical phenotypes and show unusual structural and functional features.

scientific article published on 7 September 2013

Normal Pressure Hydrocephalus and Parkinsonism: Preliminary Data on Neurosurgical and Neurological Treatment.

scientific article

Role of plasminogen in propagation of scrapie

scientific article

Atypical tauopathy with massive involvement of the white matter

scientific article published on 15 January 2008

The epsilon isoform of 14-3-3 protein is a component of the prion protein amyloid deposits of Gerstmann-Sträussler-Scheinker disease.

scientific article published in February 2007

Neocortical variation of Abeta load in fully expressed, pure Alzheimer's disease.

scientific article published in January 2010

Periodic electroencephalogram complexes in a patient with variant Creutzfeldt-Jakob disease

scientific article published on 01 February 2006

An antibody raised against a conserved sequence of the prion protein recognizes pathological isoforms in human and animal prion diseases, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy

scientific article published on June 1, 1998

Atypical frontotemporal dementia as a new clinical phenotype of Gerstmann-Straussler-Scheinker disease with the PrP-P102L mutation. Description of a previously unreported Italian family

scientific article

Deep Learning Representation from Electroencephalography of Early-Stage Creutzfeldt-Jakob Disease and Features for Differentiation from Rapidly Progressive Dementia.

scientific article published on 3 May 2016

Therapeutic approaches to prion diseases.

scientific article

Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross-sectional diffusion tensor imaging study

scientific article published on 11 July 2018

Progranulin plasma levels predict the presence of GRN mutations in asymptomatic subjects and do not correlate with brain atrophy: results from the GENFI study

scientific article published on 13 November 2017

Molecular subtypes of Alzheimer's disease.

scientific article published on 19 February 2018

An In Vivo (11)C-(R)-PK11195 PET and In Vitro Pathology Study of Microglia Activation in Creutzfeldt-Jakob Disease.

scientific article

Towards an early clinical diagnosis of sporadic CJD VV2 (ataxic type).

scientific article

A novel phenotype of sporadic Creutzfeldt-Jakob disease.

scientific article

New mutations in MAPT gene causing frontotemporal lobar degeneration: biochemical and structural characterization.

scientific article published on 22 September 2011

Stereotypic behaviors in degenerative dementias.

scientific article published on 31 May 2012

Adult metachromatic leucodystrophy: clinicopathological report of two familial cases with slow course

scientific article published on May 1, 1979

Synthetic prions with novel strain-specified properties

scientific article

Novel PSEN1 mutations (H214N and R220P) associated with familial Alzheimer's disease identified by targeted exome sequencing

scientific article

List of works by Fabrizio Tagliavini

APP mutations in the Aβ coding region are associated with abundant cerebral deposition of Aβ38.

α-Synuclein Amyloids Hijack Prion Protein to Gain Cell Entry, Facilitate Cell-to-Cell Spreading and Block Prion Replication.

Tetracyclines and prion infectivity.

Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

The semantic variant of primary progressive aphasia: clinical and neuroimaging evidence in single subjects

Expression of A2V-mutated Aβ in Caenorhabditis elegans results in oligomer formation and toxicity

An APOE haplotype associated with decreased ε4 expression increases the risk of late onset Alzheimer's disease

C9ORF72 hexanucleotide repeat number in frontotemporal lobar degeneration: a genotype-phenotype correlation study

Neurotoxic and gliotrophic activity of a synthetic peptide homologous to Gerstmann-Sträussler-Scheinker disease amyloid protein.

Preventive study in subjects at risk of fatal familial insomnia: Innovative approach to rare diseases

A novel Italian presenilin 2 gene mutation with prevalent behavioral phenotype.

Diagnostic differentiation of mild cognitive impairment due to Alzheimer's disease using a hippocampus-dependent test of spatial memory.

Detection of prion seeding activity in the olfactory mucosa of patients with Fatal Familial Insomnia

Recurrent generalized seizures, visual loss, and palinopsia as phenotypic features of neuronal ceroid lipofuscinosis due to progranulin gene mutation

Brain delivery of AAV9 expressing an anti-PrP monovalent antibody delays prion disease in mice.

White matter hyperintensities are seen only in GRN mutation carriers in the GENFI cohort

Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody.

Good gene, bad gene: new APP variant may be both

Mutations in MAPT give rise to aneuploidy in animal models of tauopathy

Cognitive reserve and TMEM106B genotype modulate brain damage in presymptomatic frontotemporal dementia: a GENFI study

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Comparison of arterial spin labeling registration strategies in the multi-center GENetic frontotemporal dementia initiative (GENFI).

Analysis of Conformational Stability of Abnormal Prion Protein Aggregates across the Spectrum of Creutzfeldt-Jakob Disease Prions

Prodromal Alzheimer's disease presenting as cerebral amyloid angiopathy-related inflammation with spontaneous amyloid-related imaging abnormalities and high cerebrospinal fluid anti-Aβ autoantibodies.

Tackling amyloidogenesis in Alzheimer's disease with A2V variants of Amyloid-β.

Atypical presentation of Creutzfeldt-Jakob disease: the first Italian case associated with E196K mutation in the PRNP gene.

Frontotemporal lobar degeneration: old knowledge and new insight into the pathogenetic mechanisms of tau mutations

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers

Different mutations at V363 MAPT codon are associated with atypical clinical phenotypes and show unusual structural and functional features.

Normal Pressure Hydrocephalus and Parkinsonism: Preliminary Data on Neurosurgical and Neurological Treatment.

Role of plasminogen in propagation of scrapie

Atypical tauopathy with massive involvement of the white matter

The epsilon isoform of 14-3-3 protein is a component of the prion protein amyloid deposits of Gerstmann-Sträussler-Scheinker disease.

Neocortical variation of Abeta load in fully expressed, pure Alzheimer's disease.

Periodic electroencephalogram complexes in a patient with variant Creutzfeldt-Jakob disease

An antibody raised against a conserved sequence of the prion protein recognizes pathological isoforms in human and animal prion diseases, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy

Atypical frontotemporal dementia as a new clinical phenotype of Gerstmann-Straussler-Scheinker disease with the PrP-P102L mutation. Description of a previously unreported Italian family

Deep Learning Representation from Electroencephalography of Early-Stage Creutzfeldt-Jakob Disease and Features for Differentiation from Rapidly Progressive Dementia.

Therapeutic approaches to prion diseases.

Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross-sectional diffusion tensor imaging study

Progranulin plasma levels predict the presence of GRN mutations in asymptomatic subjects and do not correlate with brain atrophy: results from the GENFI study

Molecular subtypes of Alzheimer's disease.

An In Vivo (11)C-(R)-PK11195 PET and In Vitro Pathology Study of Microglia Activation in Creutzfeldt-Jakob Disease.

Towards an early clinical diagnosis of sporadic CJD VV2 (ataxic type).

A novel phenotype of sporadic Creutzfeldt-Jakob disease.

New mutations in MAPT gene causing frontotemporal lobar degeneration: biochemical and structural characterization.

Stereotypic behaviors in degenerative dementias.

Adult metachromatic leucodystrophy: clinicopathological report of two familial cases with slow course

Synthetic prions with novel strain-specified properties

Novel PSEN1 mutations (H214N and R220P) associated with familial Alzheimer's disease identified by targeted exome sequencing