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List of works by Richard N. Bergman

A Better Index of Body Adiposity ⬇️

scientific article published on 01 June 2012

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

scientific article published on 10 May 2017

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

scientific article published on 24 March 2017

A Peripheral CB1R Antagonist Increases Lipolysis, Oxygen Consumption Rate, and Markers of Beiging in 3T3-L1 Adipocytes Similar to RIM, Suggesting that Central Effects Can Be Avoided

scientific article published on 10 September 2020

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

scientific article published on 13 May 2012

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

Activation of NPRs and UCP1-independent pathway following CB1R antagonist treatment is associated with adipose tissue beiging in fat-fed male dogs

scientific article published on 25 June 2019

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

Assessment of hepatic insulin extraction from in vivo surrogate methods of insulin clearance measurement.

scientific article

Association of Transcription Factor 7-Like 2 (TCF7L2) Variants With Type 2 Diabetes in a Finnish Sample

article

BASREP: a method for maintaining euglycemia during somatostatin suppression of pancreatic secretion

scientific article published on March 1, 1992

Biological, clinical and population relevance of 95 loci for blood lipids

scientific article

Biomarker models as surrogates for the disposition index in the Insulin Resistance Atherosclerosis Study ⬇️

scientific article published on November 1, 2012

CB(1) antagonism restores hepatic insulin sensitivity without normalization of adiposity in diet-induced obese dogs

scientific article

CB1R antagonist increases hepatic insulin clearance in fat-fed dogs likely via upregulation of liver adiponectin receptors

scientific article

Caval occlusion technique for hepatic venous sampling: a new approach to estimating splanchnic substrate balance in conscious dogs

scientific article published on May 1, 1979

Common Variants in Maturity-Onset Diabetes of the Young Genes Contribute to Risk of Type 2 Diabetes in Finns

article

Common variants at 30 loci contribute to polygenic dyslipidemia

scientific article

Common variants in the GDF5-UQCC region are associated with variation in human height

scientific article

Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes

scientific article published on 04 August 2008

Consistency of the disposition index in the face of diet induced insulin resistance: potential role of FFA.

scientific article

Correction: Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution.

scientific article published on 27 July 2009

Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 23 August 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Corrections: High-Fat Diet-Induced Insulin Resistance does not Increase Plasma Anandamide Levels or Potentiate Anandamide Insulinotropic Effect in Isolated Canine Islets

scientific article published on 15 June 2015

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Critical evaluation of the combined model approach for estimation of prehepatic insulin secretion ⬇️

scientific article published on January 1, 1998

Defining cutoffs to diagnose obesity using the relative fat mass (RFM): Association with mortality in NHANES 1999-2014

scientific article published on 07 January 2020

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

scientific article

Direct enhancement of insulin secretion by vagal stimulation of the isolated pancreas ⬇️

scientific article published on 01 August 1973

Dissection of hepatic versus extra-hepatic insulin clearance: Ethnic differences in childhood

scientific article published on 20 August 2018

Dose-response relationship between lymph insulin and glucose uptake reveals enhanced insulin sensitivity of peripheral tissues

scientific article published on February 1, 1992

Dynamic control of hepatic glucose metabolism: Studies by experiment and computer simulation ⬇️

scientific article published on December 1, 1975

Erratum: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article published in November 2011

Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article published in May 2010

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 23 January 2018

Essentiality of portal vein receptors in hypoglycemic counterregulation: direct proof via denervation in male canines

scientific article published on 15 January 2014

Estimating hepatic glucokinase activity using a simple model of lactate kinetics

scientific article published on 28 March 2012

Ethnic differences in carotid wall thickness. The Insulin Resistance Atherosclerosis Study

scientific article

Evaluation of SLC2A10 (GLUT10) as a candidate gene for type 2 diabetes and related traits in Finns

scientific article published in August 2005

Exenatide Treatment Alone Improves β-Cell Function in a Canine Model of Pre-Diabetes

scientific article

Fluctuations of plasma glucose and insulin in conscious dogs receiving glucose infusions ⬇️

scientific article published on April 1, 1974

Free Fatty Acid as a Link in the Regulation of Hepatic Glucose Output by Peripheral Insulin ⬇️

scientific article published on September 1, 1995

Genetic evidence of assortative mating in humans

scholarly article

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

scientific journal article

Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes

scientific article published in April 2004

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

scientific article published on 14 July 2016

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

scientific article published in June 2009

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults

scientific article published on 27 April 2017

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Glucagon-stimulated glycogenolysis: time-dependent sensitivity to insulin ⬇️

scientific article published on March 1, 1979

Glucose homeostasis during short-term and prolonged exposure to high altitudes

scientific article

Hepatic but Not Extrahepatic Insulin Clearance Is Lower in African American Than in European American Women

scientific article

Hepatic glucagon sensitivity and fasting glucose concentration in normal dogs

scientific article published on April 1, 1992

Hepatic insulin clearance is the primary determinant of insulin sensitivity in the normal dog.

scientific article published on 03 December 2013

Hepatic portal vein denervation impairs oral glucose tolerance but not exenatide's effect on glycemia.

scientific article

High-fat diet-induced insulin resistance does not increase plasma anandamide levels or potentiate anandamide insulinotropic effect in isolated canine islets

scientific article

Hundreds of variants clustered in genomic loci and biological pathways affect human height

scientific article

Hypertension and insulin resistance: role of sympathetic nervous system activity

scientific article published on November 1, 1992

Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes

scientific article published on 01 September 2019

Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus

scientific article

Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

scientific article

Importance of Hepatic Glucoreceptors in Sympathoadrenal Response to Hypoglycemia ⬇️

scientific article published on January 1, 1991

Improved estimation of anaplerosis in heart using13C NMR ⬇️

scientific article published on December 1, 1997

Increase in visceral fat per se does not induce insulin resistance in the canine model

scientific article

Increased proinsulin levels and decreased acute insulin response independently predict the incidence of type 2 diabetes in the insulin resistance atherosclerosis study

scientific article published in April 2002

Indirect effect of insulin to suppress endogenous glucose production is dominant, even with hyperglucagonemia ⬇️

scientific article published on December 15, 1997

Insulin secretion, obesity, and potential behavioral influences: results from the Insulin Resistance Atherosclerosis Study (IRAS)

scholarly article by E J Mayer-Davis et al published 1 March 2001 in Diabetes - Metabolism: Research and Reviews

Integrated control of hepatic glucose metabolism

scientific article published on February 1, 1977

Intensity and amount of physical activity in relation to insulin sensitivity: the Insulin Resistance Atherosclerosis Study

scientific article

Intravenous Insulin Infusion to Simulate Subcutaneous Absorption: Bioavailability and Metabolic Sequelae ⬇️

scientific article published on November 1, 1991

Inverse association between altitude and obesity: A prevalence study among andean and low-altitude adult individuals of Peru

scientific article

Inverse association between diabetes and altitude: a cross-sectional study in the adult population of the United States

scientific article

Large size cells in the visceral adipose depot predict insulin resistance in the canine model

scientific article published on 11 August 2011

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

scientific article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Levels of Free Fatty Acids (FFA) Are Associated with Insulin Resistance But Do Not Explain the Relationship between Adiposity and Insulin Resistance in Hispanic Americans: The IRAS Family Study ⬇️

scientific article published on July 3, 2012

Low Insulin Sensitivity is Associated with Clustering of Cardiovascular Disease Risk Factors ⬇️

scientific article published on August 15, 1997

Low insulin sensitivity (S(i) = 0) in diabetic and nondiabetic subjects in the insulin resistance atherosclerosis study: is it associated with components of the metabolic syndrome and nontraditional risk factors?

scientific article published in October 2003

Mapping Genes for NIDDM: Design of the Finland—United States Investigation of NIDDM Genetics (FUSION) Study ⬇️

scientific article published on June 1, 1998

Mechanism of Action in Dogs of Slow-Acting Insulin Analog O346 ⬇️

scientific article published on May 1, 2003

Mechanisms Responsible for Excess Weight Loss after Bariatric Surgery ⬇️

scientific article published on September 1, 2011

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

scientific article

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

scientific article

Method of Insulin Administration Has No Effect on Insulin Sensitivity Estimates From the Insulin-Modified Minimal Model Protocol ⬇️

scientific article published on December 1, 1997

Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns

scientific article

Modeling of insulin action in vivo

scientific article published on January 1, 1992

Mortality Attributed to COVID-19 in High-Altitude Populations

scientific article published on 17 August 2020

Neurohypophyseal hormone-responsive renal adenylate cyclase. IV. A random-hit matrix model for coupline in a hormone-sensitive adenylate cyclase system ⬇️

scientific article published on May 10, 1978

New concepts in extracellular signaling for insulin action: the single gateway hypothesis

scientific article published on January 1, 1997

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

scientific article

Novel Glucosensor for Hypoglycemic Detection Localized to the Portal Vein ⬇️

scientific article published on September 1, 1997

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

OPSEG: a general routine for smoothing and interpolating discrete biological data ⬇️

scientific article published on May 1, 1988

PACBERG: An adaptive program for controlling the blood sugar ⬇️

scientific article published on February 1, 1983

Performance of a multi‐marker Diabetes Risk Score in the Insulin Resistance Atherosclerosis Study (IRAS), a multi‐ethnic US cohort ⬇️

scientific article published on September 1, 2012

Peripheral Mechanisms Mediating the Sustained Antidiabetic Action of FGF1 in the Brain

scientific article published on 06 December 2018

Primacy of Hepatic Insulin Resistance in the Development of the Metabolic Syndrome Induced by an Isocaloric Moderate-Fat Diet in the Dog ⬇️

scientific article published on October 1, 2003

Proinsulin and insulin concentrations in relation to carotid wall thickness: Insulin Resistance Atherosclerosis Study

scientific article published in August 1998

Quantitative estimation of insulin sensitivity

scientific article published on June 1, 1979

Reassessment of Glucose Effectiveness and Insulin Sensitivity From Minimal Model Analysis: A Theoretical Evaluation of the Single-Compartment Glucose Distribution Assumption ⬇️

scientific article published on November 1, 1997

Relationship of insulin clearance and secretion to insulin sensitivity in non-diabetic Mexican Americans

scientific article published on March 1, 1992

Relative Fat Mass as an estimator of whole-body fat percentage among children and adolescents: A cross-sectional study using NHANES

scientific article published on 24 October 2019

Relative fat mass (RFM) as a new estimator of whole-body fat percentage ─ A cross-sectional study in American adult individuals

scientific article published on 20 July 2018

Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet

scientific article published on 5 August 2016

Rimonabant prevents additional accumulation of visceral and subcutaneous fat during high-fat feeding in dogs

scientific article published on 14 April 2009

Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study

scientific article published on October 17, 1992

Role of portal insulin delivery in the disappearance of intravenous glucose and assessment of insulin sensitivity ⬇️

scientific article published on May 1, 1998

Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes

scientific article published in January 2007

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

scientific article published on 19 December 2017

Simplified method to isolate highly pure canine pancreatic islets

scientific article published on January 2012

Simulation study of control of hepatic glycogen synthesis by glucose and insulin ⬇️

scientific article published on November 1, 1976

Simultaneous Measurement of Insulin Sensitivity, Insulin Secretion, and the Disposition Index in Conscious Unhandled Mice ⬇️

scientific article published on February 14, 2012

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

scientific article

Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases

scientific article

Subsets of Finns with high HDL to total cholesterol ratio show evidence for linkage to type 2 diabetes on chromosome 6q.

scientific article

Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database

The Barrier Within: Endothelial Transport of Hormones ⬇️

scientific article published on August 1, 2012

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The Insulin Sensitivity Index: Correlation in Dogs Between Values Determined from the Intravenous Glucose Tolerance Test and the Euglycemic Glucose Clamp ⬇️

scientific article published on April 1, 1984

The Measurement of Insulin Clearance

scientific article published on 01 September 2020

The endothelium in diabetes: Its role in insulin access and diabetic complications ⬇️

scientific article published on March 1, 2013

The genetic architecture of type 2 diabetes

scientific article (publication date: 11 July 2016)

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article

Variability of Directly Measured First-Pass Hepatic Insulin Extraction and Its Association With Insulin Sensitivity and Plasma Insulin

scientific article published on 11 May 2018

Variants in MTNR1B influence fasting glucose levels

scientific article

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels

scientific article

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