List of works - Minerva M Carrasquillo

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

scientific article

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scientific article

TREM2 Variants in Alzheimer's Disease

scientific article published on November 14, 2012

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

scientific article

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

scientific article (publication date: 15 November 2010)

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants

scientific article

Replication of CLU, CR1, and PICALM associations with alzheimer disease.

scientific article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genome-wide association study of Alzheimer's disease

scientific article

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.

scientific article

Ataxin-2 repeat-length variation and neurodegeneration

scientific article

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

Differential clinicopathologic and genetic features of late-onset amnestic dementias

scientific article published on 5 June 2014

Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma

scientific article

TREM2 is associated with increased risk for Alzheimer's disease in African Americans

scientific article published on 10 April 2015

Genome-wide association analysis of age-at-onset in Alzheimer's disease

scientific article

Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases

scientific article

Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels

scientific article

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology

scientific article published on March 2016

TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease

scientific article

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

scientific article published on 6 February 2017

Late-onset Alzheimer's risk variants in memory decline, incident mild cognitive impairment, and Alzheimer's disease

scientific article

Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications

scientific article

Replication of EPHA1 and CD33 associations with late-onset Alzheimer's disease: a multi-centre case-control study

scientific article

Replication of BIN1 association with Alzheimer's disease and evaluation of genetic interactions

scientific article

Investigation of 15 of the top candidate genes for late-onset Alzheimer's disease

scientific article

Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease

scientific article

Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).

scientific article

Genome-wide association interaction analysis for Alzheimer's disease

scientific article

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

scientific article

Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

scientific article published on 15 March 2016

Late-onset Alzheimer disease genetic variants in posterior cortical atrophy and posterior AD.

scientific article published on 26 March 2014

Evaluation of memory endophenotypes for association with CLU, CR1, and PICALM variants in black and white subjects

scientific article published on 02 May 2013

Late-onset Alzheimer disease risk variants mark brain regulatory loci

scientific article published on 23 July 2015

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

scientific article published on 8 December 2016

Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease

scientific article

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases

scientific article published on 26 October 2017

ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease

scientific article published on 10 March 2014

A multi-center study of ACE and the risk of late-onset Alzheimer's disease

scientific article published on January 2011

Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci.

scientific article published on 26 April 2016

Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

article

ABCA7 loss-of-function variants, expression, and neurologic disease risk

scientific article published on 05 January 2017

Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's disease pathology

scientific article

Association and heterogeneity at the GAPDH locus in Alzheimer's disease

scientific article

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

article by Sven J. van der Lee et al published 27 May 2019 in Acta Neuropathologica

List of works by Minerva M Carrasquillo

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

TREM2 Variants in Alzheimer's Disease

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Genetic variation in PCDH11X is associated with susceptibility to late-onset Alzheimer's disease

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants

Replication of CLU, CR1, and PICALM associations with alzheimer disease.

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genome-wide association study of Alzheimer's disease

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.

Ataxin-2 repeat-length variation and neurodegeneration

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Differential clinicopathologic and genetic features of late-onset amnestic dementias

Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma

TREM2 is associated with increased risk for Alzheimer's disease in African Americans

Genome-wide association analysis of age-at-onset in Alzheimer's disease

Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases

Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

ABCA7 Deficiency Accelerates Amyloid-β Generation and Alzheimer's Neuronal Pathology

TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

Late-onset Alzheimer's risk variants in memory decline, incident mild cognitive impairment, and Alzheimer's disease

Glutathione S-transferase omega genes in Alzheimer and Parkinson disease risk, age-at-diagnosis and brain gene expression: an association study with mechanistic implications

Replication of EPHA1 and CD33 associations with late-onset Alzheimer's disease: a multi-centre case-control study

Replication of BIN1 association with Alzheimer's disease and evaluation of genetic interactions

Investigation of 15 of the top candidate genes for late-onset Alzheimer's disease

Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease

Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).

Genome-wide association interaction analysis for Alzheimer's disease

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease

Late-onset Alzheimer disease genetic variants in posterior cortical atrophy and posterior AD.

Evaluation of memory endophenotypes for association with CLU, CR1, and PICALM variants in black and white subjects

Late-onset Alzheimer disease risk variants mark brain regulatory loci

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease

Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases

ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease

A multi-center study of ACE and the risk of late-onset Alzheimer's disease

Gene expression, methylation and neuropathology correlations at progressive supranuclear palsy risk loci.

Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

ABCA7 loss-of-function variants, expression, and neurologic disease risk

Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's disease pathology

Association and heterogeneity at the GAPDH locus in Alzheimer's disease

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity