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List of works by Lene Jorgensen

Adsorption of insulin with varying self-association profiles to a solid Teflon surface--influence on protein structure, fibrillation tendency and thermal stability.

scientific article

Alternative routes of administration for systemic delivery of protein pharmaceuticals

scientific article published on January 2008

Biodegradable nanocomposite microparticles as drug delivering injectable cell scaffolds

scientific article published on 20 July 2011

Calcipotriol delivery into the skin with PEGylated liposomes

scientific article published on 19 April 2012

Competitive adsorption of monoclonal antibodies and nonionic surfactants at solid hydrophobic surfaces

scientific article published on 01 December 2014

Complex coacervates of hyaluronic acid and lysozyme: effect on protein structure and physical stability.

scientific article

Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme.

scientific article published on 20 March 2017

Delivery of Dermatan Sulfate from Polyelectrolyte Complex-Containing Alginate Composite Microspheres for Tissue Regeneration

scientific article published on 28 February 2012

Design and characterization of core-shell mPEG-PLGA composite microparticles for development of cell-scaffold constructs

scientific article published in September 2013

Design and processing of nanogels as delivery systems for peptides and proteins.

scientific article published on June 2014

Design of cyclic RKKH peptide-conjugated PEG liposomes targeting the integrin α₂β₁ receptor.

scientific article

Determination of liposome-buffer distribution coefficients of charged drugs by capillary electrophoresis frontal analysis.

scientific article published in August 2009

Drug-liposome distribution phenomena studied by capillary electrophoresis-frontal analysis.

scientific article published in August 2008

Elucidating the mechanisms of protein antigen adsorption to the CAF/NAF liposomal vaccine adjuvant systems: effect of charge, fluidity and antigen-to-lipid ratio.

scientific article published on 25 April 2014

Formation of dielectric layers and charge regulation in protein adsorption at biomimetic interfaces

scientific article published on 09 January 2012

Incorporation of a synthetic mycobacterial monomycoloyl glycerol analogue stabilizes dimethyldioctadecylammonium liposomes and potentiates their adjuvant effect in vivo

scientific article

Influence of PEGylation with linear and branched PEG chains on the adsorption of glucagon to hydrophobic surfaces

scientific article published on 11 November 2010

Influence of acylation on the adsorption of insulin to hydrophobic surfaces

scientific article published on 29 December 2010

Influence of glycosylation on the adsorption of Thermomyces lanuginosus lipase to hydrophobic and hydrophilic surfaces.

scientific article

Interaction of Peptidomimetics with Bilayer Membranes: Biophysical Characterization and Cellular Uptake

scientific article published on 07 March 2012

Interfacial Complexes between a Protein and Lipophilic Ions at an Oil−Water Interface

scientific article published on 01 September 2010

Interfacial adsorption of insulin conformational changes and reversibility of adsorption.

scientific article

Kapp SJ, Larsson I, Van De Weert M, Ćardenas M, Jorgensen L. 2015. Competitive Adsorption of Monoclonal Antibodies and Nonionic Surfactants at Solid Hydrophobic Surfaces. 2015. J Pharm Sci 104:593-601

scientific article published on 18 June 2015

Kinetics of insulin adsorption at the oil-water interface and diffusion properties of adsorbed layers monitored using fluorescence correlation spectroscopy.

scientific article published in January 2006

Lipidation Effect on Surface Adsorption and Associated Fibrillation of the Model Protein Insulin.

scientific article published on 27 June 2016

Mechanistic study of the inhibitory activity of Geum urbanum extract against α-Synuclein fibrillation.

scientific article published on 21 June 2016

Membrane adsorption and binding, cellular uptake and cytotoxicity of cell-penetrating peptidomimetics with α-peptide/β-peptoid backbone: Effects of hydrogen bonding and α-chirality in the β-peptoid residues

scientific article published on 16 May 2012

Micropipette manipulation: a technique to evaluate the stability of water-in-oil emulsions containing proteins

scientific article published on 01 December 2004

Preparing and evaluating delivery systems for proteins.

scientific article published on 25 May 2006

Probing insulin’s secondary structure after entrapment into alginate/chitosan nanoparticles

scientific article published on 24 September 2006

Probing structural changes of proteins incorporated into water-in-oil emulsions.

scientific article

Protein Adsorption at Charged Surfaces: The Role of Electrostatic Interactions and Interfacial Charge Regulation

scientific article published on 15 February 2011

Protein adsorption and displacement at lipid layers determined by total internal reflection fluorescence (TIRF).

scientific article

Protein adsorption to poly(tetrafluoroethylene) membranes modified with grafted poly(acrylic acid) chains

scientific article published on 11 June 2020

Recent trends in stabilising peptides and proteins in pharmaceutical formulation - considerations in the choice of excipients.

scientific article

Screening of plants used in the European traditional medicine to treat memory disorders for acetylcholinesterase inhibitory activity and anti amyloidogenic activity.

scientific article

Simple measurements for prediction of drug release from polymer matrices – Solubility parameters and intrinsic viscosity

scientific article published on 07 February 2015

Studies on human insulin adsorption kinetics at an organic–aqueous interface determined using a label-free electroanalytical approach

scientific article published on 23 December 2007

Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery

scientific article published on 12 March 2017

Targeting of liposome-associated calcipotriol to the skin: Effect of liposomal membrane fluidity and skin barrier integrity

scientific article published on 16 March 2011

The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products--A Study Using Aloin and Insulin

scientific article

The importance of interfaces in protein drug delivery - why is protein adsorption of interest in pharmaceutical formulations?

scientific article published on 11 May 2011

The physical stability of the recombinant tuberculosis fusion antigens h1 and h56.

scientific article published on 19 July 2013