Search filters

List of works by Martin Fassnacht

A Copeptin-Based Approach in the Diagnosis of Diabetes Insipidus

scientific article published on 01 August 2018

Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction

scientific article published on 17 March 2020

Adrenal incidentaloma - what to do and what not?

scientific article published on 10 February 2017

Adrenocortical incidentalomas and bone: from molecular insights to clinical perspectives

scientific article published on 2 August 2018

Adrenomedullary function, obesity and permissive influences of catecholamines on body mass in patients with chromaffin cell tumours.

scientific article published on 3 March 2018

Alterations in Protein Kinase A Substrate Specificity as a Potential Cause of Cushing Syndrome

scientific article published on 01 February 2019

Antwort.

scientific article published on 6 February 2018

Assessment of VAV2 Expression Refines Prognostic Prediction in Adrenocortical Carcinoma.

scientific article

Assessment of tumor heterogeneity in treatment-naïve adrenocortical cancer patients using (18)F-FDG positron emission tomography.

scientific article published on 2 May 2016

Association of mitotane with chylomicrons and serum lipoproteins: practical implications for treatment of adrenocortical carcinoma

scientific article published on 15 December 2015

Bevacizumab plus capecitabine as a salvage therapy in advanced adrenocortical carcinoma

scientific article published on 10 November 2009

Biochemical Diagnosis of Chromaffin Cell Tumors in Patients at High and Low Risk of Disease: Plasma versus Urinary Free or Deconjugated O-Methylated Catecholamine Metabolites

scientific article published on 10 August 2018

CYP2W1 is highly expressed in adrenal glands and is positively associated with the response to mitotane in adrenocortical carcinoma.

scientific article

Cancer-testis Antigen FATE1 Expression in Adrenocortical Tumors Is Associated with A Pervasive Autoimmune Response and Is A Marker of Malignancy in Adult, but Not Children, ACC

scientific article published on 14 March 2020

Characteristics of Pediatric vs Adult Pheochromocytomas and Paragangliomas

scientific article

Clinical presentation, treatment and outcome of anaplastic thyroid carcinoma: results of a multicenter study in Germany

scientific article

Combination chemotherapy in advanced adrenocortical carcinoma

scientific article published on 2 May 2012

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

scientific article

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

article

Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome

scientific article published on 26 February 2014

Correction to: Adrenocortical incidentalomas and bone: from molecular insights to clinical perspectives

scientific article published on 01 December 2018

Cortisol-related metabolic alterations assessed by mass spectrometry assay in patients with Cushing's syndrome

scientific article published on 31 May 2017

DNA Methylation Is an Independent Prognostic Marker of Survival in Adrenocortical Cancer.

scientific article

Deficits in the management of patients with adrenocortical carcinoma in Germany

scientific article

Differential expression of the protein kinase A subunits in normal adrenal glands and adrenocortical adenomas.

scientific article published on 8 March 2017

Dosage-dependent regulation of VAV2 expression by steroidogenic factor-1 drives adrenocortical carcinoma cell invasion.

scientific article

EJE prize 2014: current and evolving treatment options in adrenocortical carcinoma: where do we stand and where do we want to go?

scientific article published on 08 April 2014

ERCC1 as predictive biomarker to platinum-based chemotherapy in adrenocortical carcinomas

scientific article published on 29 November 2017

Early Postoperative Circulating miR-483-5p Is a Prognosis Marker for Adrenocortical Cancer

scientific article published on 19 March 2020

Effects of Germline CYP2W1*6 and CYP2B6*6 Single Nucleotide Polymorphisms on Mitotane Treatment in Adrenocortical Carcinoma: A Multicenter ENSAT Study

scientific article published on 04 February 2020

Enzyme autoinduction by mitotane supported by population pharmacokinetic modelling in a large cohort of adrenocortical carcinoma patients

scientific article published on 16 October 2018

Epidemiology of adrenal crisis in chronic adrenal insufficiency: the need for new prevention strategies

scientific article

Epidermal growth factor receptor in adrenocortical tumors: analysis of gene sequence, protein expression and correlation with clinical outcome.

scientific article

Expression of LIN28 and its regulatory microRNAs in adult adrenocortical cancer.

scientific article published on 3 November 2014

Expression of excision repair cross complementing group 1 and prognosis in adrenocortical carcinoma patients treated with platinum-based chemotherapy

scientific article published on 24 February 2009

Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis

scientific article published on 14 October 2019

Gemcitabine-Based Chemotherapy in Adrenocortical Carcinoma: A Multicenter Study of Efficacy and Predictive Factors

scientific article published on 19 September 2017

Genetic Landscape of Sporadic Unilateral Adrenocortical Adenomas Without PRKACA p.Leu206Arg Mutation.

scientific article published on 7 July 2016

Glucocorticoid excess in patients with pheochromocytoma compared to paraganglioma and other forms of hypertension

scientific article published on 01 July 2020

High Diagnostic and Prognostic Value of Steroidogenic Factor-1 Expression in Adrenal Tumors

scientific article published on 21 July 2010

High incidence of adrenal crisis in educated patients with chronic adrenal insufficiency: a prospective study

scientific article published on 24 November 2014

High resolution tissue mass spectrometry imaging reveals a refined functional anatomy of the human adult adrenal gland

scientific article published on 29 January 2018

Hsp90 inhibition in adrenocortical carcinoma: Limited drug synergism with mitotane

scientific article published on 10 October 2018

Impact of USP8 Gene Mutations on Protein Deregulation in Cushing Disease

scientific article published on 01 July 2019

Impact of chronic hyponatremia on neurocognitive and neuromuscular function

scientific article published on 19 September 2018

Impaired subjective health status in 256 patients with adrenal insufficiency on standard therapy based on cross-sectional analysis

scientific article published on 7 August 2007

Improved survival in patients with stage II adrenocortical carcinoma followed up prospectively by specialized centers

scientific article published on 28 July 2010

Influence of hormonal functional status on survival in adrenocortical carcinoma: systematic review and meta-analysis

article

Integrated genomic characterization of adrenocortical carcinoma

scientific article published on 20 April 2014

Interplay between glucocorticoids and tumor-infiltrating lymphocytes on the prognosis of adrenocortical carcinoma

scientific article published on 01 May 2020

Investigating the Chemokine Receptor 4 as Potential Theranostic Target in Adrenocortical Cancer Patients

scientific article published on 4 November 2016

Lack of Ubiquitin Specific Protease 8 (USP8) Mutations in Canine Corticotroph Pituitary Adenomas

scientific article

Landscape of somatic mutations in sporadic GH-secreting pituitary adenomas.

scientific article published on 23 December 2015

Less common genotype variants of TP53 polymorphisms are associated with poor outcome in adult patients with adrenocortical carcinoma

scientific article published on 10 April 2014

Levodopa therapy in Parkinson's disease: influence on liquid chromatographic tandem mass spectrometric-based measurements of plasma and urinary normetanephrine, metanephrine and methoxytyramine

scientific article published on 19 July 2013

Limited prognostic value of the 2004 International Union Against Cancer staging classification for adrenocortical carcinoma

Linsitinib (OSI-906) versus placebo for patients with locally advanced or metastatic adrenocortical carcinoma: a double-blind, randomised, phase 3 study

scientific article published on 18 March 2015

Livin/BIRC7 expression as malignancy marker in adrenocortical tumors.

scientific article published on 21 December 2016

Long-Term Outcomes of Adjuvant Mitotane Therapy in Patients With Radically Resected Adrenocortical Carcinoma.

scientific article published on 11 January 2017

Low SGK1 expression in human adrenocortical tumors is associated with ACTH-independent glucocorticoid secretion and poor prognosis.

scientific article published on 9 October 2012

Major prognostic role of Ki67 in localized adrenocortical carcinoma after complete resection.

scientific article published on 5 January 2015

Measurements of plasma metanephrines by immunoassay vs liquid chromatography with tandem mass spectrometry for diagnosis of pheochromocytoma

scientific article published on 01 December 2014

Merits and pitfalls of mifepristone in Cushing's syndrome.

scientific article published on 16 March 2009

Metabolic impact of pheochromocytoma/paraganglioma: targeted metabolomics in patients before and after tumor removal

scientific article published on 01 December 2019

Missed clinical clues in patients with pheochromocytoma/paraganglioma discovered by imaging

scientific article published on 01 September 2018

Mitotane Inhibits Sterol-O-Acyl Transferase 1 Triggering Lipid-Mediated Endoplasmic Reticulum Stress and Apoptosis in Adrenocortical Carcinoma Cells

scientific article published on 25 August 2015

Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement

scientific article published on 16 November 2012

Mitotane monotherapy in patients with advanced adrenocortical carcinoma

scientific article published on 14 February 2018

Mutations in the deubiquitinase gene USP8 cause Cushing's disease

scientific article published on 8 December 2014

Notch1 pathway in adrenocortical carcinomas: correlations with clinical outcome

scientific article published on 15 May 2015

Novel somatic mutations in the catalytic subunit of the protein kinase A as a cause of adrenal Cushing's syndrome: a European multicentric study

scientific article published on 24 July 2014

Outcome after resection of Adrenocortical Carcinoma liver metastases: a retrospective study

scientific article published on 04 August 2017

PKA catalytic subunit mutations in adrenocortical Cushing's adenoma impair association with the regulatory subunit.

scientific article

PheoSeq: A Targeted Next-Generation Sequencing Assay for Pheochromocytoma and Paraganglioma Diagnostics

scientific article published on 25 May 2017

Pheochromocytoma - Current Recommendations on Diagnostics, Therapy and Follow-up

scientific article published on 5 December 2017

Pheochromocytoma and paraganglioma: clinical feature-based disease probability in relation to catecholamine biochemistry and reason for disease suspicion

scientific article published on 01 October 2019

Plasma methoxytyramine: clinical utility with metanephrines for diagnosis of pheochromocytoma and paraganglioma

scientific article

Predictive value of FDG-PET in patients with advanced medullary thyroid carcinoma treated with vandetanib

scientific article published on 12 October 2017

Pregnancy in Women Previously Treated for an Adrenocortical Carcinoma.

scientific article published on 13 October 2015

Prognostic factors in stage III-IV adrenocortical carcinomas (ACC): an European Network for the Study of Adrenal Tumor (ENSAT) study.

scientific article published on October 2015

Prognostic role of overt hypercortisolism in completely operated patients with adrenocortical cancer.

scientific article

Release and Decay Kinetics of Copeptin versus AVP in Response to Osmotic Alterations in Healthy Volunteers.

scientific article

Role of Endocrine Gland-Derived Vascular Endothelial Growth Factor (EG-VEGF) and Its Receptors in Adrenocortical Tumors

scientific article

Role of MDH2 pathogenic variant in pheochromocytoma and paraganglioma patients

scientific article published on 16 July 2018

Salvage Treatment of Adrenocortical Carcinoma with Trofosfamide

scientific article published on 9 March 2016

Simultaneous liquid chromatography tandem mass spectrometric determination of urinary free metanephrines and catecholamines, with comparisons of free and deconjugated metabolites

scientific article published on 9 January 2013

Single nucleotide polymorphism array profiling of adrenocortical tumors--evidence for an adenoma carcinoma sequence?

scientific article

Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation

scientific article published on 27 January 2021

Steroid Profiling for Adrenocortical Disorders: A Pathway for Omics-Based Diagnostics.

scientific article published on 10 October 2017

Sunitinib in Refractory Adrenocortical Carcinoma: A Phase II, Single-Arm, Open-Label Trial

scientific article published on 26 July 2012

Survivin in adrenocortical tumors - pathophysiological implications and therapeutic potential

scientific article

Surviving ectopic Cushing's syndrome: quality of life, cardiovascular and metabolic outcomes in comparison to Cushing's disease during long-term follow-up

scientific article published on 06 June 2018

Targeting CXCR4 (CXC Chemokine Receptor Type 4) for Molecular Imaging of Aldosterone-Producing Adenoma

scientific article published on 26 December 2017

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The New Genetic Landscape of Cushing's Disease: Deubiquitinases in the Spotlight

scientific article published on 08 November 2019

The metabolic phenotype of patients with primary aldosteronism: impact of subtype and sex – a multicenter-study of 3566 Caucasian and Asian subjects

scientific article published in 2022

The role of surgery in the management of recurrent adrenocortical carcinoma

scientific article published on 12 November 2012

Thyroid gland and the heart : Pathophysiological background, diagnostic and therapeutic consequences

scientific article published on 01 July 2018

Topoisomerase 2α and thymidylate synthase expression in adrenocortical cancer

scientific article published on 21 April 2017

Treatment of Refractory Adrenocortical Carcinoma with Thalidomide: Analysis of 27 Patients from the European Network for the Study of Adrenal Tumours Registry

scientific article published on 14 November 2018

Treatment of advanced adrenocortical carcinoma with erlotinib plus gemcitabine

scientific article published on 11 March 2008

Urine Steroid Metabolomics as a Novel Tool for Detection of Recurrent Adrenocortical Carcinoma

scientific article published on 01 March 2020

Value of Molecular Classification for Prognostic Assessment of Adrenocortical Carcinoma

scientific article published on 11 July 2019

Volumetric and texture analysis of pretherapeutic 18F-FDG PET can predict overall survival in medullary thyroid cancer patients treated with Vandetanib

scientific article published on 11 September 2018

β-catenin activation is associated with specific clinical and pathologic characteristics and a poor outcome in adrenocortical carcinoma

scientific article published on 18 November 2010

Paulina is supported by:

About Paulina

Help