List of works by Juan Luis Asensio

A dynamic combinatorial approach for the analysis of weak carbohydrate/aromatic complexes: dissecting facial selectivity in CH/π stacking interactions.

scientific article published on 25 February 2013

A dynamic perspective on the molecular recognition of chitooligosaccharide ligands by hevein domains.

scientific article

A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition: dramatic alterations in the neomycin-B protonation state upon binding to a 23-mer RNA aptamer.

scientific article published on 23 October 2006

A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4.

scientific article published in June 2005

A thorough experimental study of CH/π interactions in water: quantitative structure-stability relationships for carbohydrate/aromatic complexes

scientific article published on 30 July 2015

Carbohydrate-aromatic interactions

scientific article published on 15 June 2012

Carbohydrate-based DNA ligands: sugar-oligoamides as a tool to study carbohydrate-nucleic acid interactions.

scientific article

Chemical Interrogation of Drug/RNA Complexes: From Chemical Reactivity to Drug Design

scientific article published on 07 February 2013

Engineering O-Glycosylation Points in Non-extended Peptides: Implications for the Molecular Recognition of Short Tumor-Associated Glycopeptides

scientific article published on 08 February 2011

Experimental evidence for the existence of non-exo-anomeric conformations in branched oligosaccharides: NMR analysis of the structure and dynamics of aminoglycosides of the neomycin family

scientific article

Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance

scientific article

Finding the Right Candidate for the Right Position: A Fast NMR-Assisted Combinatorial Method for Optimizing Nucleic Acids Binders.

scientific article

G2 and DFT rigorous description of the inversion process of oxane and thiane used as simple ring systems to model sugar components

scientific article published in July 2003

Hevein domains: an attractive model to study carbohydrate-protein interactions at atomic resolution

scientific article

Impact of Aromatic Stacking on Glycoside Reactivity: Balancing CH/π and Cation/π Interactions for the Stabilization of Glycosyl-Oxocarbenium Ions

scientific article published on 20 August 2019

Modulating weak interactions for molecular recognition: a dynamic combinatorial analysis for assessing the contribution of electrostatics to the stability of CH-π bonds in water

scientific article published on 9 February 2015

Molecular recognition of aminoglycoside antibiotics by bacterial defence proteins: NMR study of the structural and conformational features of streptomycin inactivation by Bacillus subtilis aminoglycoside-6-adenyl transferase

scientific article published in August 2005

Multiple keys for a single lock: the unusual structural plasticity of the nucleotidyltransferase (4')/kanamycin complex

scientific article published in February 2012

NMR and modeling studies of protein-carbohydrate interactions: synthesis, three-dimensional structure, and recognition properties of a minimum hevein domain with binding affinity for chitooligosaccharides.

scientific article

NMR-based analysis of aminoglycoside recognition by the resistance enzyme ANT(4'): the pattern of OH/NH3(+) substitution determines the preferred antibiotic binding mode and is critical for drug inactivation.

scientific article published on 26 March 2008

On the importance of carbohydrate-aromatic interactions for the molecular recognition of oligosaccharides by proteins: NMR studies of the structure and binding affinity of AcAMP2-like peptides with non-natural naphthyl and fluoroaromatic residues.

scientific article

Rescue of the streptomycin antibiotic activity by using streptidine as a "decoy acceptor" for the aminoglycoside-inactivating enzyme adenyl transferase.

scientific article published on 13 June 2007

Role of aromatic rings in the molecular recognition of aminoglycoside antibiotics: implications for drug design.

scientific article published on September 2010

Role of conserved salt bridges in homeodomain stability and DNA binding

scientific article

Structure of the Functional Domain of φ29 Replication Organizer

scientific article published in Journal of Biological Chemistry

Structure-based design of highly crowded ribostamycin/kanamycin hybrids as a new family of antibiotics.

scientific article

The Unusual Nucleotide Recognition Properties of the Resistance Enzyme ANT(4′): Inorganic Tri/Polyphosphate as a Substrate for Aminoglycoside Inactivation

scientific article published on 01 August 2010

The impact of R53C mutation on the three-dimensional structure, stability, and DNA-binding properties of the human Hesx-1 homeodomain.

scientific article published in August 2002

The pattern of distribution of amino groups modulates the structure and dynamics of natural aminoglycosides: implications for RNA recognition.

scientific article published on 14 February 2007

The solution conformation of C-glycosyl analogues of the sialyl-Tn antigen

scientific article published on 28 March 2007

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