List of works - Bernadette McGuinness

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scientific article

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

scientific article (publication date: 15 November 2010)

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Statins for the prevention of dementia

scientific article (published 2009-04-15)

Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

scientific article

Statins for the prevention of dementia

scientific article

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Inflammation and anti-inflammatory strategies for Alzheimer's disease--a mini-review

scientific article published on 10 September 2009

Statins for the treatment of dementia

scientific article (published 2010-08-04)

Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease

scientific article

Statins for the treatment of dementia

scientific article

Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

scientific article (published 2006-04-19)

Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease

scientific article

Can statins prevent or help treat Alzheimer's disease?

scientific article published on January 2010

Alzheimer's disease-like pathology has transient effects on the brain and blood metabolome

scientific article published on 30 November 2015

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

scientific article

Attention deficits in Alzheimer's disease and vascular dementia

scientific article published in February 2010

Cochrane review on 'Statins for the treatment of dementia'.

scientific article

A novel reciprocal and biphasic relationship between membrane cholesterol and beta-secretase activity in SH-SY5Y cells and in human platelets

scientific article

The development of effective biomarkers for Alzheimer's disease: a review

scientific article published on 04 June 2012

Rivastigmine for vascular cognitive impairment

scientific article (publication date: 31 May 2013)

Plasma clusterin levels and the rs11136000 genotype in individuals with mild cognitive impairment and Alzheimer's disease

scientific article

Genetic variation in the alpha 7 nicotinic acetylcholine receptor is associated with delusional symptoms in Alzheimer's disease

scientific article published on 12 August 2008

A multi-center study of ACE and the risk of late-onset Alzheimer's disease

scientific article published on January 2011

Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation

article

Age-associated changes of brain copper, iron, and zinc in Alzheimer's disease and dementia with Lewy bodies

scientific article published in January 2014

Serum concentrations of vitamin E and carotenoids are altered in Alzheimer's disease: A case-control study

scientific article published on 19 July 2017

Plasma Antioxidant Status in Patients with Alzheimer's Disease and Cognitively Intact Elderly: A Meta-Analysis of Case-Control Studies

scientific article published in January 2018

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

article

Predicting conversion to dementia in a memory clinic: A standard clinical approach compared with an empirically defined clustering method (latent profile analysis) for mild cognitive impairment subtyping

scientific article published on 2 November 2015

Reduced estimated glomerular filtration rate in Alzheimer's disease

scientific article published in September 2009

Platelet Membrane β-Secretase Activity in Mild Cognitive Impairment and Conversion to Dementia: a Longitudinal Study

scientific article

CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study

scientific article published on 2 February 2018

Apolipoprotein epsilon4 and neuropsychological performance in Alzheimer's disease and vascular dementia

scientific article published in August 2010

Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

scientific article published on 24 July 2014

Designing appropriate clinical trials to assess ACEI use and cognitive decline in older adults with hypertension

scientific article

Variation in RTN3 and PPIL2 genes does not influence platelet membrane beta-secretase activity or susceptibility to alzheimer's disease in the northern Irish population

scientific article published in January 2009

Statin withdrawal in people with dementia.

scientific article published on 9 September 2016

Vitamin E and Alzheimer's disease: what do we know so far?

scientific article published on 18 July 2019

Northern Ireland dementia strategy

scientific article published in September 2010

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scholarly article published in Nature Genetics

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Encouraging lifestyle behaviour change in mild cognitive impairment patients: development of appropriate educational material

scientific article

Evidence That Parietal Lobe Fatty Acids May Be More Profoundly Affected in Moderate Alzheimer's Disease (AD) Pathology Than in Severe AD Pathology

scientific article published on 26 October 2018

Statins for the treatment of Alzheimer's disease and dementia

scientific article

Corrigendum: Multi-Kernel Learning with Dartel Improves Combined MRI-PET Classification of Alzheimer's Disease in AIBL Data: Group and Individual Analyses

scientific article published on 8 September 2017

The influence of TNF inhibitors on dementia incidence in patients with rheumatoid arthritis; an analysis from the BSRBR-RA.

scientific article published in March 2018

List of works by Bernadette McGuinness

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Statins for the prevention of dementia

Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

Statins for the prevention of dementia

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

Inflammation and anti-inflammatory strategies for Alzheimer's disease--a mini-review

Statins for the treatment of dementia

Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease

Statins for the treatment of dementia

Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease

Can statins prevent or help treat Alzheimer's disease?

Alzheimer's disease-like pathology has transient effects on the brain and blood metabolome

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

Attention deficits in Alzheimer's disease and vascular dementia

Cochrane review on 'Statins for the treatment of dementia'.

A novel reciprocal and biphasic relationship between membrane cholesterol and beta-secretase activity in SH-SY5Y cells and in human platelets

The development of effective biomarkers for Alzheimer's disease: a review

Rivastigmine for vascular cognitive impairment

Plasma clusterin levels and the rs11136000 genotype in individuals with mild cognitive impairment and Alzheimer's disease

Genetic variation in the alpha 7 nicotinic acetylcholine receptor is associated with delusional symptoms in Alzheimer's disease

A multi-center study of ACE and the risk of late-onset Alzheimer's disease

Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation

Age-associated changes of brain copper, iron, and zinc in Alzheimer's disease and dementia with Lewy bodies

Serum concentrations of vitamin E and carotenoids are altered in Alzheimer's disease: A case-control study

Plasma Antioxidant Status in Patients with Alzheimer's Disease and Cognitively Intact Elderly: A Meta-Analysis of Case-Control Studies

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Predicting conversion to dementia in a memory clinic: A standard clinical approach compared with an empirically defined clustering method (latent profile analysis) for mild cognitive impairment subtyping

Reduced estimated glomerular filtration rate in Alzheimer's disease

Platelet Membrane β-Secretase Activity in Mild Cognitive Impairment and Conversion to Dementia: a Longitudinal Study

CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study

Apolipoprotein epsilon4 and neuropsychological performance in Alzheimer's disease and vascular dementia

Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

Designing appropriate clinical trials to assess ACEI use and cognitive decline in older adults with hypertension

Variation in RTN3 and PPIL2 genes does not influence platelet membrane beta-secretase activity or susceptibility to alzheimer's disease in the northern Irish population

Statin withdrawal in people with dementia.

Vitamin E and Alzheimer's disease: what do we know so far?

Northern Ireland dementia strategy

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Encouraging lifestyle behaviour change in mild cognitive impairment patients: development of appropriate educational material

Evidence That Parietal Lobe Fatty Acids May Be More Profoundly Affected in Moderate Alzheimer's Disease (AD) Pathology Than in Severe AD Pathology

Statins for the treatment of Alzheimer's disease and dementia

Corrigendum: Multi-Kernel Learning with Dartel Improves Combined MRI-PET Classification of Alzheimer's Disease in AIBL Data: Group and Individual Analyses

The influence of TNF inhibitors on dementia incidence in patients with rheumatoid arthritis; an analysis from the BSRBR-RA.

Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery