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List of works by Salvatore Cuzzocrea

15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria

scientific article published in September 2004

16,16-Dimethyl prostaglandin E2 efficacy on prevention and protection from bleomycin-induced lung injury and fibrosis

scientific article

2-Pentadecyl-2-Oxazoline Reduces Neuroinflammatory Environment in the MPTP Model of Parkinson Disease

scientific article published on 14 April 2018

2-Pentadecyl-2-Oxazoline, the Oxazoline of Pea, Modulates Carrageenan-Induced Acute Inflammation

scientific article published on 30 May 2017

2-pentadecyl-2-oxazoline: Identification in coffee, synthesis and activity in a rat model of carrageenan-induced hindpaw inflammation

scientific article published on 12 April 2016

2‐Cyclopenten‐1‐one and prostaglandin J2 reduce restenosis after balloon angioplasty in rats: role of NF‐κB ⬇️

scientific article published on October 9, 2003

5-Aminoisoquinolin-1(2H)-one, a water-soluble poly (ADP-ribose) polymerase (PARP) inhibitor reduces the evolution of experimental periodontitis in rats

scientific article published in February 2007

5-Aminoisoquinolinone reduces colon injury by experimental colitis

scientific article published on 18 November 2004

5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion

scientific article

5-Arylidene-2-imino-4-thiazolidinones: design and synthesis of novel anti-inflammatory agents

scientific article

5-Lipoxygenase knockout mice exhibit a resistance to pleurisy and lung injury caused by carrageenan

scientific article published in June 2003

5-Lipoxygenase modulates colitis through the regulation of adhesion molecule expression and neutrophil migration

scientific article published in June 2005

5-lipoxygenase knockout mice exhibit a resistance to acute pancreatitis induced by cerulein

scientific article published in September 2003

5-lipoxygenase knockout mice exhibit a resistance to splanchnic artery occlusion shock

scientific article published in September 2003

5-lipoxygenase modulates the alteration of paracellular barrier function in mice ileum during experimental colitis

scientific article published on 01 April 2006

90 Y-ibritumomab tiuxetan: a nearly forgotten opportunityr

scientific article

90Y-Ibritumomab-Tiuxetan Consolidation Therapy for Advanced-Stage Mantle Cell Lymphoma After First-Line Autologous Stem Cell Transplantation: Is It Time for a Step Forward?

scientific article published on 21 November 2015

A Controlled Cortical Impact Preclinical Model of Traumatic Brain Injury

scientific article published in January 2018

A hydrogen sulfide-releasing cyclooxygenase inhibitor markedly accelerates recovery from experimental spinal cord injury

scientific article published on 30 July 2013

A new co-ultramicronized composite including palmitoylethanolamide and luteolin to prevent neuroinflammation in spinal cord injury

scientific article published on 23 July 2013

A newly identified role for superoxide in inflammatory pain

scientific article published on 26 February 2004

A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects

scientific article published on 5 May 2003

A novel adamantane derivative attenuates retinal ischemia-reperfusion damage in the rat retina through sigma1 receptors

scientific article published on 06 March 2006

A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models

scientific article

A novel protective formulation of Palmitoylethanolamide in experimental model of contrast agent induced nephropathy.

scientific article published on 13 October 2015

A phase I/II randomized, controlled, clinical trial for assessment of the efficacy and safety of β-D-mannuronic acid in rheumatoid arthritis patients.

scientific article

A protective effect of the synthetic coumarine derivative Cloricromene against DNB-colitis in the rat.

scientific article published in April 2004

A protective role for proteinase activated receptor 2 in airways of lipopolysaccharide-treated rats

scientific article

A randomized, controlled, phase II clinical trial of β-D-mannuronic acid (M2000) in pre-surgical breast cancer patients at early stage (T1-T2)

scientific article published on 01 June 2019

A role for nitric oxide-mediated peroxynitrite formation in a model of endotoxin-induced shock

scientific article

A role for superoxide in gentamicin-mediated nephropathy in rats

scientific article published in August 2002

A superoxide dismutase mimetic with catalase activity (EUK-8) reduces the organ injury in endotoxic shock

scientific article published on 01 April 2003

A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways.

scientific article published on 19 September 2014

ALIAmides Update: Palmitoylethanolamide and Its Formulations on Management of Peripheral Neuropathic Pain

scientific article published on 27 July 2020

AQX-1125, small molecule SHIP1 activator inhibits bleomycin-induced pulmonary fibrosis

scientific article

AST-120 Reduces Neuroinflammation Induced by Indoxyl Sulfate in Glial Cells

Abandon the mouse research ship? Not just yet!

scientific article

Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in mice

scientific article

Absence of endogenous interleukin-10 enhanced organ dysfunction and mortality associated to zymosan-induced multiple organ dysfunction syndrome

scientific article published on 21 December 2007

Absence of endogenous interleukin-10 enhances secondary inflammatory process after spinal cord compression injury in mice

scientific article published on 22 January 2009

Absence of endogenous interleukin-10 enhances the evolution of acute lung injury.

scientific article published in July 2002

Absence of endogenous interleukin-6 enhances the inflammatory response during acute pancreatitis induced by cerulein in mice

scientific article published in June 2002

Absence of formyl peptide receptor 1 causes endometriotic lesion regression in a mouse model of surgically-induced endometriosis

scientific article published on 31 July 2018

Absence of functional peroxisome proliferator-activated receptor-alpha enhanced ileum permeability during experimental colitis

scientific article published on 01 August 2007

Absence of inducible nitric oxide synthase reduces myocardial damage during ischemia reperfusion in streptozotocin-induced hyperglycemic mice

scientific article published in February 2004

Absence of peroxisome proliferators-activated receptors (PPAR)alpha enhanced the multiple organ failure induced by zymosan

scientific article published in November 2006

Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents

scientific article published on 13 April 2020

Acute Intracerebroventricular Administration of Palmitoylethanolamide, an Endogenous Peroxisome Proliferator-Activated Receptor- Agonist, Modulates Carrageenan-Induced Paw Edema in Mice

scientific article published on 12 June 2007

Adelmidrol + sodium hyaluronate in IC/BPS or conditions associated to chronic urothelial inflammation. A translational study

scientific article published on 22 May 2018

Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease

scientific article published on 13 September 2016

Adelmidrol, a palmitoylethanolamide analogue, as a new pharmacological treatment for the management of acute and chronic inflammation.

scientific article published on 3 September 2016

Adelmidrol, in combination with hyaluronic acid, displays increased anti-inflammatory and analgesic effects against monosodium iodoacetate-induced osteoarthritis in rats.

scientific article published on 12 December 2016

Adelmidrol: A New Promising Antioxidant and Anti-Inflammatory Therapeutic Tool in Pulmonary Fibrosis

scientific article published on 09 July 2020

Adenosine A2A receptor-selective stimulation reduces signaling pathways involved in the development of intestine ischemia and reperfusion injury

scientific article published in May 2010

Adenosine A3 receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injury

scientific article published on 12 November 2020

Administration of carnosine in the treatment of acute spinal cord injury

scientific article published on 20 July 2011

Administration of palmitoylethanolamide (PEA) protects the neurovascular unit and reduces secondary injury after traumatic brain injury in mice.

scientific article published on 3 August 2012

Adrenomedullin in inflammatory process associated with experimental pulmonary fibrosis

scientific article published on 8 April 2011

Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis

scientific article published on 25 October 2017

Agonists of peroxisome-proliferator activated receptor-gamma reduce renal ischemia/reperfusion injury

scientific article published on 3 July 2003

Amino acid levels in some brain areas of inducible nitric oxide synthase knock out mouse (iNOS-/-) before and after pentylenetetrazole kindling

scientific article published in December 2006

An In Vivo Compression Model of Spinal Cord Injury

scientific article published in January 2018

An Update of Palmitoylethanolamide and Luteolin Effects in Preclinical and Clinical Studies of Neuroinflammatory Events

scientific article published on 05 March 2020

Anti-Inflammatory and Neuroprotective Effects of Co-UltraPEALut in a Mouse Model of Vascular Dementia.

scientific article published on 6 June 2017

Anti-TNF therapy in the injured spinal cord ⬇️

scientific article published on December 23, 2010

Anti-allergic properties of Mangifera indica L. extract (Vimang) and contribution of its glucosylxanthone mangiferin

scientific article published in March 2006

Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R

scientific journal article

Anti-inflammatory and Anti-oxidant Activity of Hidrox® in Rotenone-Induced Parkinson's Disease in Mice

scientific article published on 03 September 2020

Anti-inflammatory and Antioxidant Effects of Flavonoid-Rich Fraction of Bergamot Juice (BJe) in a Mouse Model of Intestinal Ischemia/Reperfusion Injury.

scientific article published on 15 July 2016

Anti-inflammatory and anti-apoptotic effects of fumonisin B1, an inhibitor of ceramide synthase, in a rodent model of splanchnic ischemia and reperfusion injury

scientific article published on 08 July 2008

Anti-inflammatory effect of ATB-352, a H2S -releasing ketoprofen derivative, on lipopolysaccharide-induced periodontitis in rats.

scientific article published on 26 December 2017

Anti-inflammatory effect of simvastatin in an experimental model of spinal cord trauma: involvement of PPAR-α.

scientific article

Anti-inflammatory effects of adrenomedullin on acute lung injury induced by Carrageenan in mice

scientific article

Antiinflammatory activity of melatonin in central nervous system

scientific article

Antineuropathic profile of N-palmitoylethanolamine in a rat model of oxaliplatin-induced neurotoxicity

scientific article

Artemether: a new therapeutic strategy in experimental rheumatoid arthritis.

scientific article published on January 2005

Aspirin regulates expression and function of scavenger receptor-BI in macrophages: studies in primary human macrophages and in mice

scientific article (publication date: July 2006)

Astrocytes: Role and Functions in Brain Pathologies

scientific article published on 27 September 2019

Attenuation in the evolution of experimental spinal cord trauma by treatment with melatonin

scientific article

B-Cell Depletion with CD20 Antibodies as New Approach in the Treatment of Inflammatory and Immunological Events Associated with Spinal Cord Injury.

scientific article published on 23 May 2016

Bendamustine plus Rituximab Versus R-CHOP as First-Line Treatment for Patients with Follicular Lymphoma Grade 3A: Evidence from a Multicenter, Retrospective Study

scientific article published on 9 January 2018

Bendamustine plus rituximab versus R-CHOP as first-line treatment for patients with indolent non-Hodgkin's lymphoma: evidence from a multicenter, retrospective study

scientific article published on 22 April 2016

Beneficial Effects of Co-Ultramicronized Palmitoylethanolamide/Luteolin in a Mouse Model of Autism and in a Case Report of Autism.

scientific article

Beneficial effects of 5-aminoisoquinolinone, a novel, potent, water-soluble, inhibitor of poly (ADP-ribose) polymerase, in a rat model of splanchnic artery occlusion and reperfusion.

scientific article

Beneficial effects of FeTSPP, a peroxynitrite decomposition catalyst, in a mouse model of spinal cord injury

scientific article published on 16 May 2007

Beneficial effects of GPI 6150, an inhibitor of poly(ADP-ribose) polymerase in a rat model of splanchnic artery occlusion and reperfusion

scientific article published on 01 March 2002

Beneficial effects of GW274150 treatment on the development of experimental colitis induced by dinitrobenzene sulfonic acid

scientific article published on 30 December 2004

Beneficial effects of GW274150, a novel, potent and selective inhibitor of iNOS activity, in a rodent model of collagen-induced arthritis

scientific article published in October 2002

Beneficial effects of a plant histaminase in a rat model of splanchnic artery occlusion and reperfusion

scientific article published on 01 April 2007

Beneficial effects of ethyl pyruvate in a mouse model of spinal cord injury

scientific article

Biochemical Evaluation of the Antioxidant Effects of Hydroxytyrosol on Pancreatitis-Associated Gut Injury

scientific article published on 22 August 2020

Bioenergetic deficits in peripheral nerve sensory axons during chemotherapy-induced neuropathic pain resulting from peroxynitrite-mediated post-translational nitration of mitochondrial superoxide dismutase

scientific article published on 25 July 2013

Bone marrow micro-environment is a crucial player for myelomagenesis and disease progression.

scientific article published on 12 January 2017

CGS 21680, an agonist of the adenosine (A2A) receptor, decreases acute lung inflammation

scientific article published on 08 July 2011

CGS 21680, an agonist of the adenosine (A2A) receptor, reduces progression of murine type II collagen-induced arthritis

scientific article published on 15 July 2011

Calpain I inhibitor ameliorates the indices of disease severity in a murine model of cerulein-induced acute pancreatitis

scientific article

Calpain inhibitor I reduces intestinal ischemia-reperfusion injury in the rat.

scientific article published in January 2004

Cashew (Anacardium occidentale L.) Nuts Counteract Oxidative Stress and Inflammation in an Acute Experimental Model of Carrageenan-Induced Paw Edema

scientific article published on 24 July 2020

Cashew (Anacardium occidentale L.) Nuts Modulate the Nrf2 and NLRP3 Pathways in Pancreas and Lung after Induction of Acute Pancreatitis by Cerulein

scientific article published on 14 October 2020

Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes

scientific article published on 17 October 2013

Cellular stress responses, hormetic phytochemicals and vitagenes in aging and longevity

scientific article

Central administration of palmitoylethanolamide reduces hyperalgesia in mice via inhibition of NF-kappaB nuclear signalling in dorsal root ganglia

scientific article published on 20 April 2009

Ceramide: a key signaling molecule in a Guinea pig model of allergic asthmatic response and airway inflammation

scientific article

Characterization of a novel and spontaneous mouse model of inflammatory arthritis

scientific article published on 16 September 2011

Chemotherapy-induced pain is promoted by enhanced spinal adenosine kinase levels via astrocyte-dependent mechanisms

scientific article

Cloricromene conjugates with short-chain alkylamino acids: synthesis and biological evaluation

scientific article published in November 2002

Cloricromene, a coumarine derivative, reduced the development of periodontitis in rats

scientific article published on 28 March 2006

Co-Ultramicronized Palmitoylethanolamide/Luteolin Promotes Neuronal Regeneration after Spinal Cord Injury

scientific article published on 8 March 2016

Co-micronized Palmitoylethanolamide/Polydatin Treatment Causes Endometriotic Lesion Regression in a Rodent Model of Surgically Induced Endometriosis.

scientific article published on 14 October 2016

Co-ultraPEALut: Role in Preclinical and Clinical Delirium Manifestations

scientific article published on 17 June 2019

Co-ultramicronized Palmitoylethanolamide/Luteolin in the Treatment of Cerebral Ischemia: from Rodent to Man.

scientific article

Cognitive Impairment with Vascular Impairment and Degeneration ⬇️

scientific article published on November 1, 2011

Combination therapy with melatonin and dexamethasone in a mouse model of traumatic brain injury.

scientific article

Combined Effects of Potassium Perchlorate and a Neonicotinoid on Zebrafish Larvae (Danio rerio)

scientific article published in 2022

Comparative therapeutic effects of metformin and vitamin E in a model of non-alcoholic steatohepatitis in the young rat.

scientific article published on 14 December 2008

Consumption of Anacardium Occidentale L. (Cashew Nuts) Inhibits Oxidative Stress through Modulation of the Nrf2/HO-1 and NF-kB Pathways

scientific article published on 26 September 2020

Copper activates the NF-kappaB pathway in vivo.

scientific article

Copper induces type II nitric oxide synthase in vivo

scientific article published in May 2003

Correction to "Potential Eye Drop Based on a Calix[4]arene Nanoassembly for Curcumin Delivery: Enhanced Drug Solubility, Stability, and Anti-Inflammatory Effect

scientific article published on 21 March 2019

Correction: Effect of a new formulation of micronized and ultramicronized N-palmitoylethanolamine in a tibia fracture mouse model of complex regional pain syndrome

scientific article published on 25 July 2018

Costunolide and Dehydrocostuslactone, two natural sesquiterpene lactones, ameliorate the inflammatory process associated to experimental pleurisy in mice

scientific article published on 10 March 2014

Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity

scientific article published on 22 May 2008

Cytoprotective and Antioxidant Effects of Hydrolysates from Black Soldier Fly (Hermetia illucens)

scientific article published in 2023

Deficiency of NADPH Oxidase Components p47phox and gp91phox Caused Granulomatous Synovitis and Increased Connective Tissue Destruction in Experimental Arthritis Models ⬇️

scientific article published on October 1, 2003

Dexamethasone ameliorates renal ischemia-reperfusion injury

scientific article published on 24 September 2009

Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain

scientific article published on 01 November 2014

Dietary Supplementation with Palmitoyl-Glucosamine Co-Micronized with Curcumin Relieves Osteoarthritis Pain and Benefits Joint Mobility

scientific article published on 08 October 2020

Differential effects of caspase inhibitors on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney

scientific article published in October 2004

Dimethyl Fumarate Reduces Inflammatory Responses in Experimental Colitis

scientific article published on 21 December 2015

Dimethyl fumarate alleviates the nitroglycerin (NTG)-induced migraine in mice

scientific article published on 17 February 2020

Dimethyl fumarate attenuates neuroinflammation and neurobehavioral deficits induced by experimental traumatic brain injury

scientific article

Docosahexaenoic acid attenuates the early inflammatory response following spinal cord injury in mice: in-vivo and in-vitro studies.

scientific article published on 10 January 2014

Dynamics of enterocyte tight junctions: effect of experimental colitis and two different anti-TNF strategies

scientific article published on 7 February 2008

EPMA-World Congress 2015

scientific article

EUK-134 reduces renal dysfunction and injury caused by oxidative and nitrosative stress of the kidney

scientific article published on 29 January 2004

Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma

scientific article published on 01 March 2008

Effect of Apocynin, an inhibitor of NADPH oxidase, in the inflammatory process induced by an experimental model of spinal cord injury.

scientific article

Effect of N-palmitoylethanolamine-oxazoline on comorbid neuropsychiatric disturbance associated with inflammatory bowel disease

scientific article published on 16 January 2020

Effect of NADPH-oxidase inhibitors in the experimental model of zymosan-induced shock in mice

scientific article published on 31 May 2011

Effect of PEA-OXA on neuropathic pain and functional recovery after sciatic nerve crush

scientific article published on 14 September 2018

Effect of Tempol, a Membrane-Permeable Free Radical Scavenger, on In Vitro Model of Eye Inflammation on Rabbit Corneal Cells

scientific article published on 01 December 2019

Effect of a new formulation of micronized and ultramicronized N-palmitoylethanolamine in a tibia fracture mouse model of complex regional pain syndrome

scientific article

Effect of anthocyanins contained in a blackberry extract on the circulatory failure and multiple organ dysfunction caused by endotoxin in the rat.

scientific article published in August 2004

Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation

scientific article published on 11 December 2010

Effect of chronic nicotine administration on the rat lung and liver: beneficial role of melatonin

scientific article published on 28 June 2007

Effect of cyclopentanone prostaglandin 15-deoxy-delta12,14PGJ2 on early functional recovery from experimental spinal cord injury

scientific article published in August 2008

Effect of fasudil, a selective inhibitor of Rho kinase activity, in the secondary injury associated with the experimental model of spinal cord trauma

scientific article published on 25 June 2012

Effect of methylguanidine in a model of septic shock induced by LPS.

scientific article

Effect of methylguanidine in carrageenan-induced acute inflammation in the rats

scientific article published in January 2004

Effect of pea protein plus grape seed dry extract on a murine model of Candida albicans induced vaginitis

scientific article published on 26 September 2018

Effect of pyrimethamine in experimental rheumatoid arthritis.

scientific article

Effect of thalidomide on signal transduction pathways and secondary damage in experimental spinal cord trauma

scientific article

Effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) polymerase, in a mouse model of acute pancreatitis induced by cerulein

scientific article published on 15 August 2006

Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury

scientific article published in January 2002

Effects of GW274150, a novel and selective inhibitor of iNOS activity, in acute lung inflammation

scientific article published on 9 February 2004

Effects of Hypericum Perforatum, in a rodent model of periodontitis

scientific article

Effects of Hypericum perforatum extract in a rat model of ischemia and reperfusion injury

scientific article published in September 2005

Effects of Liver x receptor agonist treatment on signal transduction pathways in acute lung inflammation

scientific article published on 22 February 2010

Effects of Tempol, a membrane-permeable radical scavenger, in a rodent model periodontitis

scientific article published in October 2005

Effects of a co-micronized composite containing palmitoylethanolamide and polydatin in an experimental model of benign prostatic hyperplasia.

scientific article published on 10 June 2017

Effects of a metalloporphyrinic peroxynitrite decomposition catalyst, ww-85, in a mouse model of spinal cord injury.

scientific article published in July 2009

Effects of a new compound containing Palmitoylethanolamide and Baicalein in myocardial ischaemia/reperfusion injury in vivo

scientific article published on 19 September 2018

Effects of a polyphenol present in olive oil, oleuropein aglycone, in a murine model of intestinal ischemia/reperfusion injury

scientific article published on 11 December 2012

Effects of calpain inhibitor I on multiple organ failure induced by zymosan in the rat.

scientific article published in October 2002

Effects of cloricromene, a coumarin derivative, on endotoxin-induced uveitis in Lewis rats

scientific article published in March 2003

Effects of combination M40403 and dexamethasone therapy on joint disease in a rat model of collagen-induced arthritis

scientific article published in June 2005

Effects of combination of melatonin and dexamethasone on acute lung injury in a mice model of carrageenan-induced pleurisy

scientific article published on 01 October 2006

Effects of combination of melatonin and dexamethasone on secondary injury in an experimental mice model of spinal cord trauma

scientific article published on 01 September 2007

Effects of different natural extracts in an experimental model of benign prostatic hyperplasia (BPH).

scientific article published on 20 April 2018

Effects of genetic and pharmacological inhibition of TNF-alpha in the regulation of inflammation in macrophages

scientific article published on 18 May 2009

Effects of glycogen synthase kinase-3beta inhibition on the development of cerulein-induced acute pancreatitis in mice

scientific article published in December 2007

Effects of mitogen-activated protein kinase signaling pathway inhibition on the development of cerulein-induced acute pancreatitis in mice.

scientific article

Effects of palmitoylethanolamide and luteolin in an animal model of anxiety/depression.

scientific article published in November 2013

Effects of palmitoylethanolamide and silymarin combination treatment in an animal model of kidney ischemia and reperfusion

scientific article published on 14 May 2015

Effects of palmitoylethanolamide on intestinal injury and inflammation caused by ischemia-reperfusion in mice.

scientific article published on 2 April 2012

Effects of palmitoylethanolamide on release of mast cell peptidases and neurotrophic factors after spinal cord injury.

scientific article

Effects of palmitoylethanolamide on signaling pathways implicated in the development of spinal cord injury

scientific article published on 26 March 2008

Effects of thalidomide in a mouse model of cerulein-induced acute pancreatitis

scientific article

Effects of thymosin β4 and its N-terminal fragment Ac-SDKP on TGF-β-treated human lung fibroblasts and in the mouse model of bleomycin-induced lung fibrosis

scientific article published on 22 June 2015

Effects of verbascoside biotechnologically produced by Syringa vulgaris plant cell cultures in a rodent model of colitis

scientific article published on 26 February 2009

Effects of verbascoside, biotechnologically purified by Syringa vulgaris plant cell cultures, in a rodent model of periodontitis

article

Efficacy of Xyloglucan against Escherichia coli Extraintestinal Urinary Tract Infection: An in vivo Study

scientific article published on 16 October 2020

Efficacy of treatment with verbascoside, biotechnologically produced by Syringa vulgaris plant cell cultures in an experimental mice model of spinal cord trauma

scientific article published on 27 August 2010

Emerging biotherapies for inflammatory bowel disease

scientific article published on November 2003

Emerging drugs for acute lung injury

scientific article published on 06 January 2015

Emerging pharmacotherapy for treatment of traumatic brain injury: targeting hypopituitarism and inflammation.

scientific article published on 18 June 2015

Emerging role of PPAR-β/δ in inflammatory process associated to experimental periodontitis

scientific article

Endogenous interleukin-6 enhances the renal injury, dysfunction, and inflammation caused by ischemia/reperfusion

scientific article published on 30 November 2004

Erratum to: A new co-ultramicronized composite including palmitoylethanolamide and luteolin to prevent neuroinflammation in spinal cord injury

scientific article published on 31 May 2016

Erratum to: Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain.

scientific article

Erratum to: Palmitoylethanolamide and luteolin ameliorate development of arthritis caused by injection of collagen type II in mice

scientific article published on 5 May 2016

Erythropoietin reduces the degree of arthritis caused by type II collagen in the mouse

scientific article

Erythropoietin reduces the development of experimental inflammatory bowel disease

scientific article

Erythropoietin reduces the development of nonseptic shock induced by zymosan in mice

scientific article published in April 2006

Erythropoietin suppresses peritoneal fibrosis in rat experimental model

scientific article

Estrogen Receptor-α as a Drug Target Candidate for Preventing Lung Inflammation

scientific article

Estrogen receptor antagonist fulvestrant (ICI 182,780) inhibits the anti-inflammatory effect of glucocorticoids.

scientific article

Estrogen receptor-alpha as a drug target candidate for preventing lung inflammation

scientific article

Etanercept attenuates the development of cerulein-induced acute pancreatitis in mice: a comparison with TNF-alpha genetic deletion

scientific article published on May 2007

Etanercept reduces acute tissue injury and mortality associated to zymosan-induced multiple organ dysfunction syndrome

scientific article published on 01 May 2008

Ethyl pyruvate reduces the development of zymosan-induced generalized inflammation in mice

scientific article

Evaluation of a Product Containing Xyloglucan and Pea Protein on Skin Barrier Permeability

scientific article published on 26 August 2020

Evaluation of the Effect of α-L-Guluronic Acid (G2013) on COX-1, COX-2 Activity and Gene Expression for Introducing this Drug as a Novel NSAID with Immunomodulatory Property

scientific article published on 01 January 2018

Evaluation of the efficacy and safety of β-d-mannuronic acid in patients with ankylosing spondylitis: A 12-week randomized, placebo-controlled, phase I/II clinical trial

scientific article published on 8 November 2017

Everolimus improves memory and learning while worsening depressive- and anxiety-like behavior in an animal model of depression

scientific article published on 19 March 2016

Evidence for the role of PI(3) -kinase-AKT-eNOS signalling pathway in secondary inflammatory process after spinal cord compression injury in mice.

scientific article

Evidence for the role of mitogen-activated protein kinase signaling pathways in the development of spinal cord injury

scientific article published on 7 January 2008

Evidence for the role of peroxisome proliferator-activated receptor-beta/delta in the development of spinal cord injury

scientific article published on 22 February 2010

Exogenous T3 administration provides neuroprotection in a murine model of traumatic brain injury

scientific article published on 8 January 2013

Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes

scientific article

Extranodal diffuse large B-cell lymphoma with monoclonal gammopathy: an aggressive and primary refractory disease responding to an immunomodulatory agent

scientific article published in January 2015

FeTPPS Reduces Secondary Damage and Improves Neurobehavioral Functions after Traumatic Brain Injury

scientific article published on 7 February 2017

Fluridone as a new anti-inflammatory drug

scientific article

Focus on the Role of NLRP3 Inflammasome in Diseases

scientific article published on 13 June 2020

Formyl Peptide Receptor 1 Signaling in Acute Inflammation and Neural Differentiation Induced by Traumatic Brain Injury

scientific article published on 20 August 2020

Formyl peptide receptor 1 signalling promotes experimental colitis in mice

scientific article published on 31 January 2019

Fumaric Acid Esters Attenuate Secondary Degeneration after Spinal Cord Injury.

scientific article published on 27 November 2016

Fumonisin b1 reduces the development of multiple organ failure induced by zymosan in mice

scientific article published in February 2009

GITR gene deletion and GITR-FC soluble protein administration inhibit multiple organ failure induced by zymosan

scientific article published on 01 September 2011

GITR/GITRL: more than an effector T cell co-stimulatory system.

scientific article

GLYCOGEN SYNTHASE KINASE-3?? INHIBITORS PROTECT AGAINST THE ORGAN INJURY AND DYSFUNCTION CAUSED BY HEMORRHAGE AND RESUSCITATION

scientific article published in May 2006

GPI 6150, a PARP inhibitor, reduces the colon injury caused by dinitrobenzene sulfonic acid in the rat

scientific article

GW0742, a High-Affinity PPAR-δ Agonist, Mediates Protection in an Organotypic Model of Spinal Cord Damage

scientific article published on 01 January 2012

GW0742, a high-affinity PPAR -beta/delta agonist, inhibits acute lung injury in mice

scientific article published in April 2010

GW0742, a selective PPAR-beta/delta agonist, contributes to the resolution of inflammation after gut ischemia/reperfusion injury

scientific article published on 29 April 2010

GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury

scientific article published in March 2003

Genetic and pharmacological inhibition of GITR-GITRL interaction reduces chronic lung injury induced by bleomycin instillation

scientific article published on 29 November 2006

Glucocorticoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock

scientific article

Glucocorticoid-induced leucine zipper (GILZ) over-expression in T lymphocytes inhibits inflammation and tissue damage in spinal cord injury.

scientific article published on January 2012

Glucocorticoid-induced leucine zipper is protective in Th1-mediated models of colitis

scientific article

Glucocorticoid-induced tumor necrosis factor receptor-related (GITR)-Fc fusion protein inhibits GITR triggering and protects from the inflammatory response after spinal cord injury

scientific article published on 5 March 2008

Glutamine contributes to ameliorate inflammation after renal ischemia/reperfusion injury in rats

scientific article published on 11 March 2011

Glutamine treatment attenuates the development of ischaemia/reperfusion injury of the gut

scientific journal article

Glutamine treatment attenuates the development of organ injury induced by zymosan administration in mice

article

Glycogen synthase kinase 3beta inhibition reduces the development of nonseptic shock induced by zymosan in mice

scientific article published on 01 January 2007

Glycogen synthase kinase-3 beta inhibition reduces secondary damage in experimental spinal cord trauma

scientific article published on 06 April 2006

Glycogen synthase kinase-3beta inhibition attenuates the development of ischaemia/reperfusion injury of the gut

scientific article published on 24 March 2007

Glycogen synthase kinase-3β inhibition attenuates the degree of arthritis caused by type II collagen in the mouse

scientific article published in July 2006

Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice

scientific article published on 11 June 2008

Glycyrrhizin reduces secondary inflammatory process after spinal cord compression injury in mice

scientific article published in April 2009

Green tea polyphenol extract attenuates colon injury induced by experimental colitis

scientific article published in September 2005

Green tea polyphenol extract attenuates ischemia/reperfusion injury of the gut.

scientific article published in May 2005

Green tea polyphenol extract attenuates lung injury in experimental model of carrageenan-induced pleurisy in mice

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Green tea polyphenol extract attenuates zymosan-induced non-septic shock in mice

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Green tea polyphenols ameliorate pancreatic injury in cerulein-induced murine acute pancreatitis

scientific article published in November 2009

High density lipoprotein (HDL) reduces renal ischemia/reperfusion injury.

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High-density lipoproteins reduce the intestinal damage associated with ischemia/reperfusion and colitis

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Hormesis, cellular stress response and neuroinflammation in schizophrenia: Early onset versus late onset state

scientific article published on 29 November 2016

Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity

scientific article published on August 2011

Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice.

scientific article published on 4 December 2014

Hyperbaric oxygen and sepsis: time to recognize

scientific article published on 21 July 2005

Hyperbaric oxygen therapy prevents coagulation disorders in an experimental model of multiple organ failure syndrome

scientific article published on 15 September 2006

Hyperbaric oxygen therapy prevents vascular derangement during zymosan-induced multiple-organ-failure syndrome.

scientific article published on 12 February 2004

Hyperbaric oxygen therapy reduces the toll-like receptor signaling pathway in multiple organ failures

scientific article published on 13 May 2011

Hyperglycemia in streptozotocin-induced diabetic rat increases infarct size associated with low levels of myocardial HO-1 during ischemia/reperfusion.

scientific article published in March 2005

Hypericum perforatum attenuates the development of carrageenan-induced lung injury in mice

scientific article published on 10 November 2005

Hypericum perforatum attenuates the development of cerulein-induced acute pancreatitis in mice

scientific article published in February 2006

Hypericum perforatum treatment: effect on behaviour and neurogenesis in a chronic stress model in mice

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Ibuprofen-arginine generates nitric oxide and has enhanced anti-inflammatory effects.

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Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity.

scientific article published on 6 February 2017

Immunomodulatory effects of etanercept in an experimental model of spinal cord injury

scientific article published on 22 November 2005

Implication of allopregnanolone in the antinociceptive effect of N-palmitoylethanolamide in acute or persistent pain

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In vitro and in vivo properties of a fully human IgG1 monoclonal antibody that combats multidrug resistant Pseudomonas aeruginosa

scientific article published on 20 June 2012

In vitro, ex vivo and in vivo immunopharmacological activities of the isoxazoline compound VGX-1027: Modulation of cytokine synthesis and prevention of both organ-specific and systemic autoimmune diseases in murine models

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Increased GILZ expression in transgenic mice up-regulates Th-2 lymphokines

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Increased carrageenan-induced acute lung inflammation in old rats

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Increased oxidative-related mechanisms in the spinal cord injury in old rats

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Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia

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Inducible nitric oxide synthase mediates bone loss in ovariectomized mice

scientific article published in March 2003

Inducible nitric oxide synthase-deficient mice exhibit resistance to the acute pancreatitis induced by cerulein

scientific article published in May 2002

Inflammasomes, hormesis, and antioxidants in neuroinflammation: Role of NRLP3 in Alzheimer disease.

scientific article published on 8 November 2016

Inflammation and programmed cell death in Alzheimer's disease: comparison of the central nervous system and peripheral blood.

scientific article published on 21 January 2014

Inflammatory and cell death pathways in brain and peripheral blood in Parkinson's disease

scientific article published on January 2015

Infliximab and etanercept are equally effective in reducing enterocyte APOPTOSIS in experimental colitis

scientific article published on 3 July 2008

Inhibition of ceramide biosynthesis ameliorates pathological consequences of spinal cord injury

scientific article published in June 2009

Inhibition of inducible nitric oxide synthase in vitro and in vivo by a water-soluble extract of Wendita calysina leaves

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Inhibition of inducible nitric oxide synthase reduces renal ischemia/reperfusion injury

scientific article published in March 2002

Inhibition of inflammasome activation improves lung acute injury induced by carrageenan in a mouse model of pleurisy

scientific article published in May 2017

Inhibition of nitric oxide biosynthesis by anthocyanin fraction of blackberry extract

scientific article published on 6 March 2006

Inhibition of poly(ADP-ribose) polymerase prevents allergen-induced asthma-like reaction in sensitized Guinea pigs

scientific article published on 13 July 2004

Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma

scientific article published on 29 June 2006

Inhibition of the nuclear factor-kappaB activation with pyrrolidine dithiocarbamate attenuating inflammation and oxidative stress after experimental spinal cord trauma in rats

scientific article published in October 2004

Inhibition of tyrosine kinase-mediated cellular signalling by Tyrphostins AG126 and AG556 modulates secondary damage in experimental spinal cord trauma

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Inhibition of tyrosine-kinase-mediated cellular signaling by tyrphostins AG 126 and AG556 modulates murine experimental acute pancreatitis

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Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury

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Inhibitors of NADPH oxidase reduce the organ injury in hemorrhagic shock

scientific article published in February 2005

Inhibitors of calpain activation (PD150606 and E-64) and renal ischemia-reperfusion injury

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Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma

scientific article published on 27 September 2004

Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and the development of bleomycin-induced lung injury

scientific article published on 11 January 2005

Interferon Alpha Has a Strong Anti-tumor Effect in Philadelphia-negative Myeloproliferative Neoplasms

scientific article published on 01 April 2019

International multicenter randomized, placebo-controlled phase III clinical trial of β-D-mannuronic acid in rheumatoid arthritis patients

scientific article published on 02 January 2019

Introduction of β-d-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression.

scientific article published on 25 April 2017

Involvement Of TLR4 and PPAR-α Receptors in Host Response and NLRP3 Inflammosome Activation, Against Pulmonary Infection with Pseudomosas Aeruginosa

scientific article published on 15 March 2018

Involvement of 5-lipoxygenase in spinal cord injury

scientific article published in September 2005

Involvement of leukotriene pathway in the pathogenesis of ischemia-reperfusion injury and septic and non-septic shock

scientific article published in April 2009

Involvements of Hyperhomocysteinemia in Neurological Disorders

scientific article published on 06 January 2021

Is radiotherapy still necessary for diffuse large B-cell lymphoma therapy?

scientific article published on 01 April 2015

KU0063794, a Dual mTORC1 and mTORC2 Inhibitor, Reduces Neural Tissue Damage and Locomotor Impairment After Spinal Cord Injury in Mice

scientific article published on 10 March 2016

Lenalidomide in Relapsed or Refractory Diffuse Large B-Cell Lymphoma: Is It a Valid Treatment Option?

scientific article published on 5 July 2016

Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size

scientific article published on July 2002

Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways

scientific article published on 17 October 2008

Lipoteichoic acid from Staphylococcus aureus reduces renal ischemia/reperfusion injury

scientific article published in October 2002

Liver X receptor agonist treatment reduced splanchnic ischemia and reperfusion injury

scientific article published on 22 December 2009

Liver X receptor agonist treatment regulates inflammatory response after spinal cord trauma

scientific article published on 4 November 2009

Liver X receptors activation, through TO901317 binding, reduces neuroinflammation in Parkinson's disease

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Loading Imatinib inside targeted nanoparticles to prevent Bronchiolitis Obliterans Syndrome

scientific article published on 26 November 2020

Long-term betamethasone 21-phosphate disodium treatment has distinct effects in CD1 and DBA/2 mice on animal behavior accompanied by opposite effects on neurogenesis

scientific article published on 5 October 2014

Lung resident mesenchymal cells isolated from patients with the Bronchiolitis Obliterans Syndrome display a deregulated epigenetic profile

scientific article published on 24 July 2018

M2000: a revolution in pharmacology.

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M40403 prevents myocardial injury induced by acute hyperglycaemia in perfused rat heart.

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MEK inhibition suppresses the development of lung fibrosis in the bleomycin model.

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MK801 attenuates secondary injury in a mouse experimental compression model of spinal cord trauma

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Management of Traumatic Brain Injury: From Present to Future

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Mannuronic Acid in Low-Risk and Intermediate-1-Risk Myelodysplastic Syndromes

scientific article published on 16 February 2020

Maternal adaptation in pregnant hypertensive rats: improvement of vascular and inflammatory variables and oxidative damage in the kidney.

scientific article published on 16 April 2009

Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis

scientific article published on 21 April 2008

Melatonin Plus Folic Acid Treatment Ameliorates Reserpine-Induced Fibromyalgia: An Evaluation of Pain, Oxidative Stress, and Inflammation

scientific article published on 06 December 2019

Melatonin limits lung injury in bleomycin treated mice

scientific article published in September 2005

Melatonin modulates signal transduction pathways and apoptosis in experimental colitis

scientific article published in November 2006

Melatonin prevents lipopolysaccharide-induced hyporeactivity in rat.

scientific article published in April 2004

Melatonin reduces hyperalgesia associated with inflammation

scientific article published on November 2010

Melatonin reduces oxidative damage and increases survival of mice infected with Schistosoma mansoni

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Melatonin reduces stress-activated/mitogen-activated protein kinases in spinal cord injury

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Melatonin regulates matrix metalloproteinases after traumatic experimental spinal cord injury

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Melatonin treatment mimics the antidepressant action in chronic corticosterone-treated mice

scientific article published in June 2010

Melatonin's stimulatory effect on adult hippocampal neurogenesis in mice persists after ovariectomy

scientific article published on 06 June 2011

Methylguanidine reduces the development of non septic shock induced by zymosan in mice

scientific article published in August 2004

Mice lacking the 110-kD isoform of poly(ADP-ribose) glycohydrolase are protected against renal ischemia/reperfusion injury

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Micronized palmitoylethanolamide reduces joint pain and glial cell activation

scientific article published on 18 August 2018

Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain.

scientific article published on 28 August 2014

Middle Cerebral Artery Occlusion by an Intraluminal Suture Method

scientific article published in January 2018

Modeling and biological evaluation of 3,3'-(1,2-ethanediyl)bis[2-(4-methoxyphenyl)-thiazolidin-4-one], a new synthetic cyclooxygenase-2 inhibitor

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Modulation of Dkk-3 and claudin-5 as new therapeutic strategy in the treatment of meningiomas

scientific article published on 7 August 2017

Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats ⬇️

scientific article published on 04 December 2010

Modulation of NLRP3 Inflammasome through Formyl Peptide Receptor 1 (Fpr-1) Pathway as a New Therapeutic Target in Bronchiolitis Obliterans Syndrome

scientific article published on 20 March 2020

Modulation of acute and chronic inflammation of the lung by GITR and its ligand.

scientific article published on June 2007

Modulation of inflammatory response after spinal cord trauma with deferoxamine, an iron chelator

scientific article published in June 2010

Modulation of nitric oxide homeostasis in a mouse model of spinal cord injury

scientific article published in February 2006

Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors

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Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma.

scientific article published on February 2013

Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Inhibitor as a Novel Therapeutic Tool for Lung Injury

scientific article published on 20 October 2020

Multidisciplinary approach to prostatitis

scientific article published on 18 January 2019

Multiple mechanisms of dimethyl fumarate in amyloid β-induced neurotoxicity in human neuronal cells.

scientific article published on 9 October 2017

Myrtucommulone from Myrtus communis exhibits potent anti-inflammatory effectiveness in vivo

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N-Palmitoylethanolamide-Oxazoline Protects against Middle Cerebral Artery Occlusion Injury in Diabetic Rats by Regulating the SIRT1 Pathway

scientific article published on 29 September 2019

N-Palmitoylethanolamine and Neuroinflammation: a Novel Therapeutic Strategy of Resolution

scientific article published on 09 June 2015

N-Palmitoylethanolamine-Oxazoline (PEA-OXA) as a New Therapeutic Strategy to Control Neuroinflammation: Neuroprotective Effects in Experimental Models of Spinal Cord and Brain Injury.

scientific article published on 17 January 2017

N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion

scientific article published on 17 January 2019

N-acetyl-L-cysteine reduces Leishmania amazonensis-induced inflammation in BALB/c mice

scientific article published on 13 January 2020

N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone reduces severity of experimental spinal cord injury

scientific article published on 01 March 2007

N-palmitoylethanolamide Prevents Parkinsonian Phenotypes in Aged Mice.

scientific article published on 19 March 2018

NADPH-oxidase 2 activation promotes opioid-induced antinociceptive tolerance in mice ⬇️

scientific article published on February 27, 2013

NMDA-receptor activation and nitroxidative regulation of the glutamatergic pathway during nociceptive processing

scientific article published on 18 February 2010

Natural almond skin reduced oxidative stress and inflammation in an experimental model of inflammatory bowel disease.

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Neuroinflammation and Immunity: A New Pharmacological Target in Depression.

scientific article published on 20 March 2016

Neuroinflammation and neurohormesis in the pathogenesis of Alzheimer’s disease and Alzheimer-linked pathologies: modulation by nutritional mushrooms

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Neuronal-like differentiated SH-SY5Y cells adaptation to a mild and transient H2 O2 -induced oxidative stress.

scientific article published on 12 February 2018

Neuroprotection and enhanced recovery with hypericum perforatum extract after experimental spinal cord injury in mice

scientific article published on 01 June 2006

Neuroprotection by association of palmitoylethanolamide with luteolin in experimental Alzheimer's disease models: the control of neuroinflammation.

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Neuroprotective Effect of Artesunate in Experimental Model of Traumatic Brain Injury

scientific article published on 31 July 2018

Neuroprotective Effects of Co-UltraPEALut on Secondary Inflammatory Process and Autophagy Involved in Traumatic Brain Injury.

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Neuroprotective Effects of Temsirolimus in Animal Models of Parkinson's Disease

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Neuroprotective activities of palmitoylethanolamide in an animal model of Parkinson's disease

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Neuroprotective effects of olprinone after cerebral ischemia/reperfusion injury in rats

scientific article published on 17 August 2011

Neuroprotective features of carnosine in oxidative driven diseases.

scientific article published on August 2011

Neutralization of extracellular NAMPT (nicotinamide phosphoribosyltransferase) ameliorates experimental murine colitis

scientific article published on 27 April 2020

Neutralization of tumor necrosis factor-related apoptosis-inducing ligand reduces spinal cord injury damage in mice

scientific article published on 27 January 2010

Neutrophil elastase plays a non-redundant role in remodeling the venular basement membrane and neutrophil diapedesis post-ischemia/reperfusion injury

scientific article published on 22 March 2019

Nitric oxide in the injured spinal cord: synthases cross-talk, oxidative stress and inflammation

scientific article published on April 2007

Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase

scientific article published on 03 January 2007

Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice

scientific article published on October 2004

Novel Combination of COX-2 Inhibitor and Antioxidant Therapy for Modulating Oxidative Stress Associated with Intestinal Ischemic Reperfusion Injury and Endotoxemia

scientific article published on 28 September 2020

Oleuropein aglycone, an olive oil compound, ameliorates development of arthritis caused by injection of collagen type II in mice

scientific article published on 31 August 2011

Olprinone attenuates the development of ischemia/reperfusion injury of the gut.

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Olprinone, a PDE3 inhibitor, modulates the inflammation associated with myocardial ischemia-reperfusion injury in rats

scientific article published on 27 October 2010

Olprinone, a specific phosphodiesterase (PDE)-III inhibitor, reduces the development of multiple organ dysfunction syndrome in mice

scientific article published on 28 December 2010

On the selectivity of superoxide dismutase mimetics and its importance in pharmacological studies

scientific article published on October 2003

Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases

scientific article published on 18 February 2017

Oral Supplementation with Ultramicronized Palmitoylethanolamide for Joint Disease and Lameness Management in Four Jumping Horses: A Case Report

scientific article published on 21 August 2020

Oral Ultramicronized Palmitoylethanolamide: Plasma and Tissue Levels and Spinal Anti-hyperalgesic Effect.

scientific article published on 20 March 2018

Oral administration effects of β-d-mannuronic acid (M2000) on Th17 and regulatory T cells in patients with ankylosing spondylitis.

scientific article published on 22 February 2018

Osteoporosis and alzheimer pathology: Role of cellular stress response and hormetic redox signaling in aging and bone remodeling

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Oxidative stress as the leading cause of acute myocardial infarction in diabetics

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Oxidative stress in septic shock and disseminated intravascular coagulation

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PARG activity mediates intestinal injury induced by splanchnic artery occlusion and reperfusion

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PARP inhibition treatment in a nonconventional experimental mouse model of chronic asthma

scientific article published on 7 September 2016

PD98059, a specific MAP kinase inhibitor, attenuates multiple organ dysfunction syndrome/failure (MODS) induced by zymosan in mice

scientific article published on 9 October 2009

PDE 7 inhibitors: new potential drugs for the therapy of spinal cord injury

scientific article published on 31 January 2011

PPAR-alpha Contributes to the Anti-Inflammatory Activity of Verbascoside in a Model of Inflammatory Bowel Disease in Mice

scientific article published on 30 June 2010

PPAR-alpha contributes to the anti-inflammatory activity of 17beta-estradiol

scientific article published on 15 September 2009

PPAR-alpha modulate the anti-inflammatory effect of glucocorticoids in the secondary damage in experimental spinal cord trauma.

scientific article published on 13 February 2009

PPAR-α Modulates the Anti-Inflammatory Effect of Melatonin in the Secondary Events of Spinal Cord Injury.

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PPARα mediates the anti-inflammatory effect of simvastatin in an experimental model of zymosan-induced multiple organ failure

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Palmitoylethanolamide and Polydatin combination reduces inflammation and oxidative stress in vascular injury.

scientific article published in July 2017

Palmitoylethanolamide and Related ALIAmides: Prohomeostatic Lipid Compounds for Animal Health and Wellbeing

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Palmitoylethanolamide and luteolin ameliorate development of arthritis caused by injection of collagen type II in mice.

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Palmitoylethanolamide in homeostatic and traumatic central nervous system injuries

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Palmitoylethanolamide is a New Possible Pharmacological Treatment for the Inflammation Associated with Trauma

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Palmitoylethanolamide modulates pentobarbital-evoked hypnotic effect in mice: involvement of allopregnanolone biosynthesis

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Palmitoylethanolamide reduces early renal dysfunction and injury caused by experimental ischemia and reperfusion in mice

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Palmitoylethanolamide treatment reduces retinal inflammation in streptozotocin-induced diabetic rats

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Pelagia noctiluca (Scyphozoa) crude venom injection elicits oxidative stress and inflammatory response in rats.

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Peroxisome proliferator-activated receptor β/δ agonist GW0742 ameliorates cerulein- and taurocholate-induced acute pancreatitis in mice

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Peroxisome proliferator-activated receptor-alpha contributes to the anti-inflammatory activity of glucocorticoids

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Peroxisome proliferator-activated receptor-alpha contributes to the resolution of inflammation after renal ischemia/reperfusion injury

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Peroxisome proliferator-activated receptor-alpha modulates the anti-inflammatory effect of glucocorticoids in a model of inflammatory bowel disease in mice

scientific article published in March 2009

Peroxisome proliferator-activated receptors and acute lung injury

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Peroxisome proliferator-activated receptors and acute lung injury

scientific article published on 01 January 2007

Peroxisome proliferator-activated receptors and shock state.

scientific article published on 28 December 2006

Peroxisome proliferator-activated receptors gamma ligands and ischemia and reperfusion injury

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Peroxisome proliferator-activated receptors ligands and ischemia-reperfusion injury

scientific article published on 13 March 2007

Pharmacodynamical Effects of Orally Administered Exenatide Nanoparticles Embedded in Gastro-resistant Microparticles

scientific article published on 18 October 2018

Pharmacological actions of melatonin in acute and chronic inflammation

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Pharmacological and clinical overview of cloperastine in treatment of cough ⬇️

scientific article published on March 7, 2011

Pharmacological inhibition of leukotrienes in an animal model of bleomycin-induced acute lung injury

scientific article published on 21 November 2006

Phenylpropanoid glycosides from plant cell cultures induce heme oxygenase 1 gene expression in a human keratinocyte cell line by affecting the balance of NRF2 and BACH1 transcription factors

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Phosphodiesterase as a new therapeutic target for the treatment of spinal cord injury and neurodegenerative diseases

scientific article published on January 2014

Pim kinases in hematological malignancies: where are we now and where are we going?

scientific article published on 10 December 2014

Plant histaminase as an investigational drug in splanchnic artery occlusion and reperfusion

scientific article published in August 2008

Plumericin prevents intestinal inflammation and oxidative stress in vitro and in vivo

scientific article published on 02 December 2019

Poly(ADP-ribose) glycohydrolase activity mediates post-traumatic inflammatory reaction after experimental spinal cord trauma

scientific article published on 6 July 2006

Post-ischaemic thyroid hormone treatment in a rat model of acute stroke

scientific article published on 13 March 2013

Potential Eye Drop Based on a Calix[4]arene Nanoassembly for Curcumin Delivery: Enhanced Drug Solubility, Stability, and Anti-Inflammatory Effect.

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Potential therapeutic effect of antioxidant therapy in shock and inflammation

scientific article published on May 2004

Predictivity and sensitivity of animal models of arthritis

scientific article published on 15 August 2008

Pretreatment with EPO reduces the injury and dysfunction caused by ischemia/reperfusion in the mouse kidney in vivo

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Prevention of carrageenan-induced pleurisy in mice by anti-CD30 ligand monoclonal antibody

scientific article published in October 2004

Preventive and therapeutic effects of thymosin β4 N-terminal fragment Ac-SDKP in the bleomycin model of pulmonary fibrosis

scientific article published on 27 March 2016

Probiotics reduce the inflammatory response induced by a high-fat diet in the liver of young rats

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Proinflammatory role of glucocorticoid-induced TNF receptor-related gene in acute lung inflammation

scientific article published on 01 July 2006

Protective Effect of Epigallocatechin-3-Gallate (EGCG) in Diseases with Uncontrolled Immune Activation: Could Such a Scenario Be Helpful to Counteract COVID-19?

scientific article published on 21 July 2020

Protective Effect of Hydroxytyrosol Against Oxidative Stress Induced by the Ochratoxin in Kidney Cells: in vitro and in vivo Study

scientific article published on 31 March 2020

Protective Effect of Hydroxytyrosol on LPS-Induced Inflammation and Oxidative Stress in Bovine Endometrial Epithelial Cell Line

scientific article published on 23 October 2020

Protective Effect of Silibinin on Lipopolysaccharide-Induced Inflammatory Responses in Equine Peripheral Blood Mononuclear Cells, an In Vitro Study

scientific article published on 03 November 2020

Protective Effects of Ultramicronized Palmitoylethanolamide (PEA-um) in Myocardial Ischaemia and Reperfusion Injury in VIVO

scientific article published on 01 August 2016

Protective Effects of Xyloglucan in Association with the Polysaccharide Gelose in an Experimental Model of Gastroenteritis and Urinary Tract Infections

scientific article published on 22 June 2018

Protective effect of Arbutus unedo aqueous extract in carrageenan-induced lung inflammation in mice

scientific article published on 27 December 2007

Protective effect of Hypericum perforatum in zymosan-induced multiple organ dysfunction syndrome: Relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity

scientific article published on 15 June 2006

Protective effect of a new hyaluronic acid -carnosine conjugate on the modulation of the inflammatory response in mice subjected to collagen-induced arthritis

scientific article published on 25 February 2020

Protective effect of apocynin, a NADPH-oxidase inhibitor, against contrast-induced nephropathy in the diabetic rats: A comparison with n-acetylcysteine

scientific article published on 09 November 2011

Protective effect of melatonin against the inflammatory response elicited by crude venom from isolated nematocysts of Pelagia noctiluca (Cnidaria, Scyphozoa).

scientific article published on 27 May 2009

Protective effect of orally administered carnosine on bleomycin-induced lung injury

scientific article published on 12 January 2007

Protective effect of polyphenols in an inflammatory process associated with experimental pulmonary fibrosis in mice.

scientific article published in September 2015

Protective effect of verbascoside in activated C6 glioma cells: possible molecular mechanisms

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Protective effects of Celecoxib on lung injury and red blood cells modification induced by carrageenan in the rat.

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Protective effects of Colomast®, A New Formulation of Adelmidrol and Sodium Hyaluronate, in A Mouse Model of Acute Restraint Stress

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Protective effects of M40401, a selective superoxide dismutase mimetic, on zymosan-induced nonseptic shock

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Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury

scientific article published on 27 November 2002

Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo

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Protective effects of a coumarin derivative in diabetic rats

scientific article published on 11 March 2009

Protective effects of anthocyanins from blackberry in a rat model of acute lung inflammation

scientific article published in August 2003

Protective effects of apocynin, an inhibitor of NADPH oxidase activity, in splanchnic artery occlusion and reperfusion

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Protective effects of cyanidin-3-O-glucoside from blackberry extract against peroxynitrite-induced endothelial dysfunction and vascular failure

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Protective effects of glycyrrhizin in a gut hypoxia (ischemia)-reoxygenation (reperfusion) model

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Protective effects of relaxin in ischemia/reperfusion-induced intestinal injury due to splanchnic artery occlusion

scientific article published on 17 July 2006

Protective effects of thymosin β4 in a mouse model of lung fibrosis

scientific article published on 01 October 2012

Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy.

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Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation

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Pyrrolidine dithiocarbamate attenuates the development of organ failure induced by zymosan in mice

scientific article published on 17 July 2003

Pyrrolidine dithiocarbamate reduced experimental periodontitis

scientific article published on 5 April 2006

Pyrrolidine dithiocarbamate reduces renal dysfunction and injury caused by ischemia/reperfusion of the rat kidney

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Pyrrolidine dithiocarbamate reduces the severity of cerulein-induced murine acute pancreatitis

scientific article published in December 2003

Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling and In Vivo Proof-of-Concept Efficacy in Acute Pancreatitis

scientific article published on 30 October 2018

ROLE OF ENDOGENOUS AND EXOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR alpha IN THE DEVELOPMENT OF BLEOMYCIN-INDUCED LUNG INJURY.

scientific article published in December 2005

ROLE of endogenous peroxisome proliferator-activated receptor-alpha (PPAR-alpha) ligands in the development of gut ischemia and reperfusion in mice

scientific article published on 01 January 2006

Recombinant Human Activated Protein C (Xigris) Attenuates Murine Cerulein-Induced Acute Pancreatitis Via Regulation of Nuclear Factor κB and Apoptotic Pathways ⬇️

scientific article published on 01 May 2012

Reconstituted high-density lipoprotein attenuates organ injury and adhesion molecule expression in a rodent model of endotoxic shock

scientific article published in December 2003

Red Carrot Cells Cultured in vitro Are Effective, Stable, and Safe Ingredients for Skin Care, Nutraceutical, and Food Applications

scientific article published on 21 October 2020

Redox modulation of cellular stress response and lipoxin A4 expression by Coriolus versicolor in rat brain: Relevance to Alzheimer's disease pathogenesis.

scientific article published on 30 September 2015

Redox modulation of cellular stress response and lipoxin A4 expression by Hericium Erinaceus in rat brain: relevance to Alzheimer's disease pathogenesis

scientific article published on 9 July 2016

Reduced development of experimental periodontitis by treatment with M40403, a superoxide dismutase mimetic

scientific article published in June 2005

Reduction in the development of cerulein-induced acute pancreatitis by treatment with M40401, a new selective superoxide dismutase mimetic

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Reduction in the evolution of murine type II collagen-induced arthritis by treatment with rosiglitazone, a ligand of the peroxisome proliferator-activated receptor gamma

scientific article published in December 2003

Reduction of ischemic brain injury by administration of palmitoylethanolamide after transient middle cerebral artery occlusion in rats

scientific article published on 13 August 2012

Reduction of renal ischemia-reperfusion injury in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton

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Reduction of the multiple organ injury and dysfunction caused by endotoxemia in 5-lipoxygenase knockout mice and by the 5-lipoxygenase inhibitor zileuton

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Regulation of prostaglandin generation in carrageenan-induced pleurisy by inducible nitric oxide synthase in knockout mice

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Repetitive Transcranial Magnetic Stimulation as a Novel Therapy in Animal Models of Traumatic Brain Injury

scientific article published in January 2016

Reply to Letter to Editor: "Kriek R., Marketing messages in pharmacological papers and scientific chapters: The case of palmitoylethanolamide and its formulations" [Pharmacol Res (2014) 10.1016/j.phrs.2014.04.007]

scientific article published on 20 May 2014

Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice

scientific article published on 3 November 2009

Role of 5-lipoxygenase in the multiple organ failure induced by zymosan

scientific article published on 6 July 2004

Role of Fibroblast Growth Factors Receptors (FGFRs) in Brain Tumors, Focus on Astrocytoma and Glioblastoma

scientific article published on 18 December 2020

Role of IL-10 in hepatocyte tight junction alteration in mouse model of experimental colitis

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Role of Metabotropic Glutamate Receptors in Neurological Disorders

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Role of PPAR-delta in the development of zymosan-induced multiple organ failure: an experiment mice study

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Role of TNF-alpha in ileum tight junction alteration in mouse model of restraint stress

scientific article published on 28 February 2008

Role of TNF-alpha in lung tight junction alteration in mouse model of acute lung inflammation

scientific article published on 30 October 2007

Role of Toll like receptor 4 signaling pathway in the secondary damage induced by experimental spinal cord injury

scientific article

Role of endogenous and exogenous ligands for the peroxisome proliferators activated receptors alpha (PPAR-alpha) in the development of inflammatory bowel disease in mice

scientific article published in December 2004

Role of endogenous glutathione in the secondary damage in experimental spinal cord injury in mice

scientific article published on 07 June 2007

Role of endogenous ligands for the peroxisome proliferators activated receptors alpha in the secondary damage in experimental spinal cord trauma

scientific article published on 01 July 2005

Role of glucocorticoid-induced TNF receptor family gene (GITR) in collagen-induced arthritis

scientific article published in August 2005

Role of induced nitric oxide in the initiation of the inflammatory response after postischemic injury

scientific article published in August 2002

Role of inflammation and apoptosis in multiple sclerosis: Comparative analysis between the periphery and the central nervous system.

scientific article published on 29 August 2015

Role of melatonin supplementation in neurodegenerative disorders

scientific article published on January 2014

Role of nitric oxide and reactive oxygen species in arthritis

scientific article published on January 2006

Role of nitroso radicals as drug targets in circulatory shock

scientific article published on June 2009

Role of peroxisome proliferator-activated receptor-alpha in acute pancreatitis induced by cerulein

scientific article published on 08 June 2006

Role of peroxisome proliferator-activated receptor-alpha in ileum tight junction alteration in mouse model of restraint stress

scientific article published on 25 June 2009

Role of poly(ADP-ribose) glycohydrolase (PARG) in shock, ischemia and reperfusion

scientific article

Role of poly(ADP-ribose) glycohydrolase in the development of inflammatory bowel disease in mice

scientific article published on 29 September 2006

Role of tight junction derangement in the endothelial dysfunction elicited by exogenous and endogenous peroxynitrite and poly(ADP-ribose) synthetase

scientific article published in November 2002

Role of tumor necrosis factor-alpha in acute pancreatitis: from biological basis to clinical evidence

scientific article published on August 2007

Roles of fatty acid ethanolamides (FAE) in traumatic and ischemic brain injury.

scientific article published on 27 May 2014

Roles of nitric oxide and superoxide in inflammation

scientific article

Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2, ligands of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma), reduce ischaemia/reperfusion injury of the gut.

scientific article published on 11 August 2003

Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute inflammation

scientific article

Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces acute pancreatitis induced by cerulein

scientific article published on 24 February 2004

Rosiglitazone, a ligand of the peroxisome proliferator-activated receptor-gamma, reduces the development of nonseptic shock induced by zymosan in mice

scientific article published in February 2004

SOD mimetics are coming of age.

scientific article

Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain

scientific article published on 28 November 2019

Selective CB2 inverse agonist JTE907 drives T cell differentiation towards a Treg cell phenotype and ameliorates inflammation in a mouse model of inflammatory bowel disease

scientific article published on 12 December 2018

Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation.

scientific article

Selective adenosine A2A receptor agonists and antagonists protect against spinal cord injury through peripheral and central effects ⬇️

scientific article published on 12 April 2011

Shock, inflammation and PARP.

scientific article

Signal transduction pathways involved in protective effects of melatonin in C6 glioma cells

scientific article published on January 2008

Sodium Butyrate Exerts Neuroprotective Effects in Spinal Cord Injury

scientific article published on 18 September 2018

Sodium Propionate Contributes to Tumor Cell Growth Inhibition through PPAR-γ Signaling

scientific article published in 2022

Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism

scientific article

Sphingosine 1-phosphate receptor subtype 1 (S1PR1) as a therapeutic target for brain trauma

scientific article published on 8 January 2018

Sphingosylphosphorylcholine reduces the organ injury/dysfunction and inflammation caused by endotoxemia in the rat.

scientific article published in February 2008

Spinal NADPH oxidase is a source of superoxide in the development of morphine-induced hyperalgesia and antinociceptive tolerance

scientific article

Spinal ceramide and neuronal apoptosis in morphine antinociceptive tolerance

scientific article published on 23 July 2009

Spinal ceramide modulates the development of morphine antinociceptive tolerance via peroxynitrite-mediated nitroxidative stress and neuroimmune activation

scientific article published on 25 November 2008

Spinal mitochondrial-derived peroxynitrite enhances neuroimmune activation during morphine hyperalgesia and antinociceptive tolerance

scientific article published on 27 February 2013

Splanchnic ischemia and reperfusion injury is reduced by genetic or pharmacological inhibition of TNF-α

scientific article published on 08 January 2007

Stable depletion of poly (ADP-ribose) polymerase-1 reduces in vivo melanoma growth and increases chemosensitivity

scientific article published on 24 April 2008

Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors

scientific article published on 30 November 2020

Superoxide dismutase mimetics

scientific article

Superoxide, NO, peroxynitrite and PARP in circulatory shock and inflammation

scientific article published on January 2009

Superoxide, superoxide dismutase and ischemic injury

scientific article published in June 2002

Superoxide-related signaling cascade mediates nuclear factor-kappaB activation in acute inflammation

scientific article published in August 2004

Superoxide: a key player in hypertension

scientific article

Supplementation with SCFAs Re-Establishes Microbiota Composition and Attenuates Hyperalgesia and Pain in a Mouse Model of NTG-Induced Migraine

scientific article published on 27 April 2022

Susceptibility of erythrocytes from different sources to xenobiotics-induced lysis

scientific article published on 26 March 2019

Synergic Therapeutic Potential of PEA-Um Treatment and NAAA Enzyme Silencing In the Management of Neuroinflammation

scientific article published on 11 October 2020

Synergistic interaction between methotrexate and a superoxide dismutase mimetic: pharmacologic and potential clinical significance

scientific article published on 01 December 2005

TAK1 Inhibitor Enhances the Therapeutic Treatment for Glioblastoma

scientific article published on 25 December 2020

TEMPONE reduces renal dysfunction and injury mediated by oxidative stress of the rat kidney

scientific article

TLR-4/Wnt modulation as new therapeutic strategy in the treatment of glioblastomas

TLR4 absence reduces neuroinflammation and inflammasome activation in Parkinson's diseases in vivo model

scientific article published on 11 December 2018

TLR7/8 in the Pathogenesis of Parkinson's Disease

scientific article published on 09 December 2020

TNF-alpha as a therapeutic target in acute pancreatitis--lessons from experimental models.

scientific article published on 30 March 2007

TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome

scientific article

Targeting inflammation: new therapeutic approaches in chronic kidney disease (CKD).

scientific article published on 03 March 2014

Targeting selectins for the treatment of inflammatory diseases

scientific article published on 27 September 2013

Targeting the overproduction of peroxynitrite for the prevention and reversal of paclitaxel-induced neuropathic pain

scientific article published on May 2012

Targeting the peroxisome proliferator-activated receptors (PPARs) in spinal cord injury ⬇️

scientific article published on August 1, 2011

Tempol reduces the activation of nuclear factor-kappaB in acute inflammation

scientific article published in August 2004

Teupolioside, a phenylpropanoid glycosides of Ajuga reptans, biotechnologically produced by IRBN22 plant cell line, exerts beneficial effects on a rodent model of colitis

scientific article

Thalidomide suppresses sclerosing encapsulating peritonitis in a rat experimental model

scientific article published in September 2009

Thalidomide treatment reduces colon injury induced by experimental colitis

scientific article

Thalidomide treatment reduces the alteration of paracellular barrier function in mice ileum during experimental colitis

scientific article

The Anti-Inflammatory and Antioxidant Effects of Sodium Propionate

scientific article published on 24 April 2020

The Anti-Inflammatory and Antioxidant Potential of Pistachios (Pistacia vera L.) In Vitro and In Vivo

scientific article

The Antioxidant Activity of Pistachios Reduces Cardiac Tissue Injury of Acute Ischemia/Reperfusion (I/R) in Diabetic Streptozotocin (STZ)-Induced Hyperglycaemic Rats.

scientific article published on 6 February 2018

The Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale L. Cashew Nuts in a Mouse Model of Colitis

scientific article published on 20 March 2020

The Association of Palmitoylethanolamide with Luteolin Decreases Autophagy in Spinal Cord Injury.

scientific article

The Association of Palmitoylethanolamide with Luteolin Decreases Neuroinflammation and Stimulates Autophagy in Parkinson's Disease Model

scientific article published on 20 August 2015

The NAMPT inhibitor FK866 reverts the damage in spinal cord injury

scientific article published on 10 April 2012

The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson's Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-κB/Nuclear Transcription Factor Related to NF-E2.

scientific article published on 23 December 2016

The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury

scientific article

The Protective Effects of Pre- and Post-Administration of Micronized Palmitoylethanolamide Formulation on Postoperative Pain in Rats

scientific article published on 18 October 2020

The Role of Cashew (Anacardium occidentale L.) Nuts on an Experimental Model of Painful Degenerative Joint Disease

scientific article published on 10 June 2020

The anti-inflammatory and antioxidant effects of bergamot juice extract (BJe) in an experimental model of inflammatory bowel disease

scientific article

The anti-inflammatory effects of palmitoylethanolamide (PEA) on endotoxin-induced uveitis in rats

scientific article published on 28 April 2015

The antioxidative property of melatonin against brain ischemia

scientific article published on 24 April 2016

The association of adelmidrol with sodium hyaluronate displays beneficial properties against bladder changes following spinal cord injury in mice

scientific article published in PLoS ONE

The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation

scientific article published in May 2002

The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure.

scientific article published in February 2004

The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat.

scientific article

The cyclopentenone prostaglandin 15-deoxydelta(12,14)-prostaglandin J2 attenuates the development of zymosan-induced shock

scientific article published on 15 March 2005

The development and maintenance of paclitaxel-induced neuropathic pain require activation of the sphingosine 1-phosphate receptor subtype 1.

scientific article

The effects of a polyphenol present in olive oil, oleuropein aglycone, in an experimental model of spinal cord injury in mice.

scientific article published on 8 February 2012

The effects of oleuropein aglycone, an olive oil compound, in a mouse model of carrageenan-induced pleurisy

article

The effects of β-D-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the murine monocyte/macrophage, J774 cell line.

scientific article

The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.

scientific article published on 25 January 2011

The neuroprotective effects of micronized PEA (PEA-m) formulation on diabetic peripheral neuropathy in mice

scientific article published on 25 July 2019

The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat.

scientific article published in November 2002

The potent inhibitory effect of β-D-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property on anti-cyclic citrullinated peptide antibodies, rheumatoid factor and anti-dsDNA antibodies in patients with rheumatoid arthritis.

scientific article published on 21 March 2017

The renal injury and inflammation caused by ischemia-reperfusion are reduced by genetic inhibition of TNF-αR1: a comparison with infliximab treatment

scientific article published on 3 January 2013

The role of 5-lipoxygenase and leukotrienes in shock and ischemia-reperfusion injury

scientific article published on 22 January 2007

The role of Annexin A1 and formyl peptide receptor 2/3 signaling on chronic corticosterone-induced depression-like behaviors and impairment in hippocampal-dependent memory

scientific article published on 06 January 2020

The role of cycloxygenase-2 in the rodent kidney following ischaemia/reperfusion injury in vivo

scientific article published on 08 February 2007

The role of endogenous and exogenous ligands for the peroxisome proliferator-activated receptor alpha (PPAR-alpha) in the regulation of inflammation in macrophages.

scientific article

The role of nitric oxide synthases in lung inflammation.

scientific article published on November 2007

The role of the peroxisome proliferator-activated receptor-alpha (PPAR-alpha) in the regulation of acute inflammation

scientific article published on 24 February 2006

The selective adenosine A2A receptor agonist CGS 21680 reduces JNK MAPK activation in oligodendrocytes in injured spinal cord

scientific article

The tyrosine kinase inhibitor tyrphostin AG126 reduces renal ischemia/reperfusion injury in the rat.

scientific article published in November 2003

Therapeutic Efficacy of Palmitoylethanolamide and Its New Formulations in Synergy with Different Antioxidant Molecules Present in Diets

scientific article published on 11 September 2019

Therapeutic manipulation of peroxynitrite attenuates the development of opiate-induced antinociceptive tolerance in mice

scientific article published on November 2007

Therapeutic potential of dinitrobenzene sulfonic acid (DNBS)-induced colitis in mice by targeting IL-1β and IL-18

scientific article published on 28 June 2018

Therapeutic potential of flavonoids in the treatment of chronic venous insufficiency

scientific article published on 02 December 2020

Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine

scientific article

Thymosin β4 protects C57BL/6 mice from bleomycin-induced damage in the lung.

scientific article

Thymosin β4 reduces IL-17-producing cells and IL-17 expression, and protects lungs from damage in bleomycin-treated mice

scientific article published on 14 February 2014

Thyroid hormone autoantibodies: are they a better marker to detect early thyroid damage in patients with hematologic cancers receiving tyrosine kinase inhibitor or immunoregulatory drug treatments?

scientific article published on 09 June 2016

Topical Application of Adelmidrol + -Traumatic Acid Enhances Skin Wound Healing in a Streptozotocin-Induced Diabetic Mouse Model

scientific article published on 23 August 2018

Topical Delivery of Curcumin by Choline-Calix[4]arene-Based Nanohydrogel Improves Its Therapeutic Effect on a Psoriasis Mouse Model

scientific article published on 17 July 2020

Traumatic Brain Injury Leads to Development of Parkinson's Disease Related Pathology in Mice

scientific article published on 13 October 2016

Traumatic brain injury: oxidative stress and neuroprotection.

scientific article published on 10 May 2013

Treatment With a Flavonoid-Rich Fraction of Bergamot Juice Improved Lipopolysaccharide-Induced Periodontitis in Rats

scientific article published on 01 January 2018

Treatment with Luteolin Improves Lipopolysaccharide-Induced Periodontal Diseases in Rats

scientific article published on 21 October 2020

Treatment with PARP-1 inhibitors, GPI 15427 or GPI 16539, ameliorates intestinal damage in rat models of colitis and shock

scientific article published on 28 November 2005

Treatment with a novel poly(ADP-ribose) glycohydrolase inhibitor reduces development of septic shock-like syndrome induced by zymosan in mice

scientific article

Treatment with green tea extract attenuates secondary inflammatory response in an experimental model of spinal cord trauma

scientific article published on April 2009

Tyrphostin AG 126 reduces intestinal ischemia-reperfusion injury in the rat.

scientific article published on 17 February 2006

Tyrphostin reduces the organ injury in haemorrhagic shock: role of inducible nitric oxide synthase

scientific article published in September 2003

UCP2 Regulates Mitochondrial Fission and Ventromedial Nucleus Control of Glucose Responsiveness

scientific article published on February 2016

Ultramicronized Palmitoylethanolamide and Paracetamol, a New Association to Relieve Hyperalgesia and Pain in a Sciatic Nerve Injury Model in Rat ⬇️

scientific article published on 15 May 2020

Ultramicronized palmitoylethanolamide (PEA-um(®)) in the treatment of idiopathic pulmonary fibrosis.

scientific article published on 8 July 2016

Up-regulation of prostaglandin biosynthesis by leukotriene C4 in elicited mice peritoneal macrophages activated with lipopolysaccharide/interferon-{gamma}.

scientific article published on 26 July 2005

Uric acid protects against secondary damage after spinal cord injury

scientific article

Vaccination with IL-6 analogues induces autoantibodies to IL-6 and influences experimentally induced inflammation

article by Pia Galle et al published December 2007 in International Immunopharmacology

WY 14643, a potent exogenous PPAR-alpha ligand, reduces intestinal injury associated with splanchnic artery occlusion shock

scientific article published in October 2004

WY-14643, a Potent Peroxisome Proliferator Activator Receptor-α PPAR-α Agonist Ameliorates the Inflammatory Process Associated to Experimental Periodontitis

scientific article published on 27 December 2010

mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy

scientific article

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