List of works by Valentina Escott-Price

A Precision Medicine Initiative for Alzheimer's disease: the road ahead to biomarker-guided integrative disease modeling

scientific article

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease.

scientific article published on 19 June 2017

A comprehensive screening of copy number variability in dementia with Lewy bodies

scientific article published on 24 October 2018

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A data-driven investigation of relationships between bipolar psychotic symptoms and schizophrenia genome-wide significant genetic loci.

scientific article published on 19 April 2018

A family based study implicates solute carrier family 1-member 3 (SLC1A3) gene in attention-deficit/hyperactivity disorder

scientific article

A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis

scientific article

A neuropsychological investigation of the genome wide associated schizophrenia risk variant NRGN rs12807809.

scientific article published on 26 November 2010

A novel Alzheimer disease locus located near the gene encoding tau protein.

scientific article

A novel computational approach for predicting complex phenotypes in Drosophila (starvation-sensitive and sterile) by deriving their gene expression signatures from public data

scientific article published on 26 October 2020

A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease

scientific article published on 7 December 2012

A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease

scientific article published on 13 November 2013

A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia

scientific article published on 01 January 2020

Additional rare variant analysis in Parkinson's disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance

scientific article

Age-dependent effect of APOE and polygenic component on Alzheimer's disease

scientific article published on 30 April 2020

An examination of single nucleotide polymorphism selection prioritization strategies for tests of gene-gene interaction

scientific article published on 9 April 2011

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

scientific article

Analysis of Intellectual Disability Copy Number Variants for Association With Schizophrenia

scientific article published on September 2016

Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk

scientific article published on October 2013

Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies

scientific article published on 29 January 2020

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Analysis of shared heritability in common disorders of the brain

Association Between Schizophrenia-Related Polygenic Liability and the Occurrence and Level of Mood-Incongruent Psychotic Symptoms in Bipolar Disorder

scientific article published on 22 November 2017

Association of Genetic Liability to Psychotic Experiences With Neuropsychotic Disorders and Traits

scientific article published on 25 September 2019

Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

scholarly article by Miruna C. Barbu et al published July 2018 in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Association of cerebrospinal fluid α-synuclein with total and phospho-tau181 protein concentrations and brain amyloid load in cognitively normal subjective memory complainers stratified by Alzheimer's disease biomarkers

scientific article published on 26 July 2018

Associations Between Schizophrenia Polygenic Liability, Symptom Dimensions, and Cognitive Ability in Schizophrenia

scientific article published in October 2021

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

BRAF and NRAS Locus-Specific Variants Have Different Outcomes on Survival to Colorectal Cancer.

scientific article published on 4 November 2016

C9orf72, AAO and ancestry help discriminating behavioural from language variants in FTLD cohorts

scientific article published on 17 September 2020

Cognitive Performance Among Carriers of Pathogenic Copy Number Variants: Analysis of 152,000 UK Biobank Subjects

scientific article

Cognitive performance and functional outcomes of carriers of pathogenic copy number variants: analysis of the UK Biobank.

scientific article

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

scientific article

Common polygenic variation enhances risk prediction for Alzheimer's disease

scientific article published on 21 October 2015

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

scientific article published on 26 February 2018

Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

article

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

scientific article published on 7 June 2021

Comparison of Genetic Liability for Sleep Traits Among Individuals With Bipolar Disorder I or II and Control Participants

scientific article published on 21 November 2019

Comprehensive analysis of colorectal cancer-risk loci and survival outcome: A prognostic role for CDH1 variants

scientific article published on 14 November 2019

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Convergent evidence that oligodendrocyte lineage transcription factor 2 (OLIG2) and interacting genes influence susceptibility to schizophrenia

scientific article

Correction: The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function

scientific article published on 30 July 2019

De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia

scientific article published on 13 January 2020

Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data

scientific article

Disentangling the biological pathways involved in early features of Alzheimer's disease in the Rotterdam Study.

scientific article published on 26 February 2018

Effects of differential genotyping error rate on the type I error probability of case-control studies

scientific article published on 06 April 2006

Effects of genomic copy number variants penetrant for schizophrenia on cortical thickness and surface area in healthy individuals: analysis of the UK Biobank

scientific article published on 14 August 2020

Effects of pathogenic CNVs on physical traits in participants of the UK Biobank

scientific article published on 04 December 2018

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scholarly article published in Nature Genetics

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

article

Evaluation of an approximation method for assessment of overall significance of multiple-dependent tests in a genomewide association study

scientific article published on 17 October 2011

Evaluation of cumulative cognitive deficits from electroconvulsive therapy

scientific article published on 19 November 2015

Evidence for Genetic Overlap Between Schizophrenia and Age at First Birth in Women

scientific article

Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia

scientific article

Exploring the indirect effects of catechol-O-methyltransferase (COMT) genotype on psychotic experiences through cognitive function and anxiety disorders in a large birth cohort of children.

scientific article published on 27 May 2014

From Polygenic Scores to Precision Medicine in Alzheimer's Disease: A Systematic Review

scientific article published on 30 March 2020

Gender differences in CNV burden do not confound schizophrenia CNV associations.

scientific article published on 17 May 2016

Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease

scientific article published on 08 July 2019

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

scientific article

Genes, pathways and risk prediction in Alzheimer's disease

scientific article published on 01 November 2019

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.

scientific article

Genetic analysis suggests high misassignment rates in clinical Alzheimer's cases and controls

scientific article published on 22 January 2019

Genetic differences between five European populations

scientific article published on 08 July 2010

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

scientific article (publication date: 15 November 2010)

Genetic liability to schizophrenia is negatively associated with educational attainment in UK Biobank

scientific article published on 04 January 2019

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genetic risk and age in Parkinson's disease: Continuum not stratum

scientific article published on 17 March 2015

Genetic risk for alzheimer disease is distinct from genetic risk for amyloid deposition

scientific article published on 01 July 2019

Genetic risk for bipolar disorder and psychopathology from childhood to early adulthood

scientific article published on 25 December 2018

Genetic variability in response to amyloid beta deposition influences Alzheimer's disease risk

scientific article published on 10 October 2019

Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression

article

Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders

scientific article published on 05 December 2016

Genome-wide analysis in UK Biobank identifies four loci associated with mood instability and genetic correlation with major depressive disorder, anxiety disorder and schizophrenia

scientific article published on 30 November 2017

Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases

scientific article published on 2 November 2015

Genome-wide analysis of over 106,000 individuals identifies 9 neuroticism-associated loci

Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci.

scientific article published on 12 April 2016

Genome-wide analysis of self-reported risk-taking behaviour and cross-disorder genetic correlations in the UK Biobank cohort.

scientific article published on 2 February 2018

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.

scientific article published on 26 April 2018

Genome-wide association study identifies 30 loci associated with bipolar disorder.

scientific article

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scientific article

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

scientific article

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Genomic profiling and diagnostic biomarkers in Alzheimer's disease

scientific article published on 11 July 2017

Heritability and genetic variance of dementia with Lewy bodies

scientific article published on 03 April 2019

How allele frequency and study design affect association test statistics with misrepresentation errors

scientific article published on 30 October 2013

Identification of loci associated with schizophrenia by genome-wide association and follow-up

scientific article

Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects.

scientific article published in October 2009

Investigating associations between genetic risk for bipolar disorder and cognitive functioning in childhood

scientific article published on 19 August 2019

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

scientific article published on 16 December 2017

Is the MC1R variant p.R160W associated with Parkinson's?

scientific article published on 21 September 2015

Longevity GWAS Using the Drosophila Genetic Reference Panel

scientific article

Machine learning for genetic prediction of psychiatric disorders: a systematic review

scientific article published on 26 June 2020

Medical consequences of pathogenic CNVs in adults: analysis of the UK Biobank

scientific article published on 20 October 2018

Meta-analysis of genetic association with diagnosed Alzheimer's disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries

scientific article published on 29 October 2010

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

scientific article

No Evidence for Enrichment in Schizophrenia for Common Allelic Associations at Imprinted Loci

scientific article published on 3 December 2015

No evidence that extended tracts of homozygosity are associated with Alzheimer's disease.

scientific article published on 2 August 2011

POLARIS: Polygenic LD-adjusted risk score approach for set-based analysis of GWAS data.

scientific article published on 12 March 2018

PRECISION MEDICINE - The Golden Gate for Detection, Treatment and Prevention of Alzheimer's Disease

scientific article published on 06 September 2016

Pattern Recognition Receptor Polymorphisms as Predictors of Oxaliplatin Benefit in Colorectal Cancer

scientific article published on 01 August 2019

Permutation-based approaches do not adequately allow for linkage disequilibrium in gene-wide multi-locus association analysis

scientific article

Polygenic risk and hazard scores for Alzheimer's disease prediction

scholarly article by Ganna Leonenko et al published March 2019 in Annals of clinical and translational neurology

Polygenic risk and pleiotropy in neurodegenerative diseases

scientific article published on 20 May 2020

Polygenic risk for schizophrenia and season of birth within the UK Biobank cohort

scientific article published on 04 March 2018

Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort

scientific article published on 09 September 2020

Polygenic risk of Parkinson disease is correlated with disease age at onset

scientific article published on 13 March 2015

Polygenic risk score analysis of pathologically confirmed Alzheimer disease

scientific article published on 20 July 2017

Polygenic score prediction captures nearly all common genetic risk for Alzheimer's disease

scientific article published on 5 August 2016

Population structure and genome-wide patterns of variation in Ireland and Britain

scientific article

Predictive modeling of schizophrenia from genomic data: Comparison of polygenic risk score with kernel support vector machines approach

scientific article published on 04 December 2018

Proton pump inhibitors and dementia risk: Evidence from a cohort study using linked routinely collected national health data in Wales, UK

scientific article published on 18 September 2020

Psychosis and the level of mood incongruence in Bipolar Disorder are related to genetic liability for Schizophrenia

article published in 2017

Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia

scientific article

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

scientific article published on 01 July 2019

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Strong evidence that GNB1L is associated with schizophrenia

scientific article

Strong evidence that KIAA0319 on chromosome 6p is a susceptibility gene for developmental dyslexia

scientific article

Targeted Sequencing of 10,198 Samples Confirms Abnormalities in Neuronal Activity and Implicates Voltage-Gated Sodium Channels in Schizophrenia Pathogenesis

scientific article published on 01 October 2018

The Correlation between Inflammatory Biomarkers and Polygenic Risk Score in Alzheimer's Disease

scientific article

The Relationship Between Common Variant Schizophrenia Liability and Number of Offspring in the UK Biobank

scientific article published on 04 January 2019

The Relationship Between Common Variant Schizophrenia Liability and Number of Offspring in the UK Biobank: Response to Lawn et al

scientific article published on 01 July 2019

The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia

scientific article published on 01 February 2020

The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function

scientific article published on 05 June 2019

The penetrance of copy number variations for schizophrenia and developmental delay.

scientific article

The role of the major histocompatibility complex region in cognition and brain structure: a schizophrenia GWAS follow-up

scientific article published in August 2013

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

scientific article

The use of polygenic risk scores to identify phenotypes associated with genetic risk of bipolar disorder and depression: A systematic review

scientific article published on 15 February 2018

The use of polygenic risk scores to identify phenotypes associated with genetic risk of schizophrenia: Systematic review

scientific article published on 9 November 2017

Translating genetic risk of Alzheimer's disease into mechanistic insight and drug targets

scientific article

Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease

scientific article published on 13 August 2012

Using genome-wide complex trait analysis to quantify ‘missing heritability’ in Parkinson's disease

scientific article published on 14 February 2013

Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder

scientific article published in October 2010

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