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List of works by Rainer Malik

17q25 Locus is associated with white matter hyperintensity volume in ischemic stroke, but not with lacunar stroke status

scientific article

A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach

scientific article

APOE ɛ2 is associated with white matter hyperintensity volume in CADASIL

scientific article published on 29 April 2015

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Analysis of shared heritability in common disorders of the brain

Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality: A Meta-analysis of Population-Based Studies

scientific article published on 04 November 2020

Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms

scientific article published on 3 May 2017

Author Correction: Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

scientific article published on 22 December 2020

Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study

scientific article

Cerebrovascular Disease Knowledge Portal: An Open-Access Data Resource to Accelerate Genomic Discoveries in Stroke

scientific article published on 15 January 2018

Challenges and Opportunities in Stroke Genetics

scientific article published on 15 March 2018

Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke: Meta-Analysis of Population-Based Studies Involving 17 180 Individuals

scientific article published on 03 September 2019

Clinical spectrum, underlying etiologies and radiological characteristics of cortical superficial siderosis

scientific article published on 11 April 2015

Combination of text-mining algorithms increases the performance

scientific article published on 09 June 2006

Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities

scientific article published on 10 June 2020

Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families

article by Padhraig Gormley et al published September 2018 in Neuron

Common coding variant in SERPINA1 increases the risk for large artery stroke

scientific article

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke

scientific article published on 2 September 2012

Comparative conservation analysis of the human mitotic phosphoproteome

scientific article published on 20 April 2008

Compartment-resolved Proteomic Analysis of Mouse Aorta during Atherosclerotic Plaque Formation Reveals Osteoclast-specific Protein Expression

scientific article published on 4 December 2017

Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies

scientific article published on September 2014

Current concepts and clinical applications of stroke genetics

scientific article published on April 2014

Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study

scientific article

Cysteine-sparing CADASIL mutations in NOTCH3 show proaggregatory properties in vitro

scientific article published on 20 January 2015

Decreased CSF Levels of ß-Amyloid in Patients With Cortical Superficial Siderosis

article published in 2019

Deficiency of the stroke relevant HDAC9 gene attenuates atherosclerosis in accord with allele-specific effects at 7p21.1.

scientific article published on 11 November 2014

Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease

scientific article published in 2021

Differences in Common Genetic Predisposition to Ischemic Stroke by Age and Sex

scientific article

Differential effects of PCSK9 variants on risk of coronary disease and ischaemic stroke

scientific article published on 17 July 2017

Erratum: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

scientific article published in October 2016

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

scientific article published in July 2017

Evaluation of the Low-Specificity Protease Elastase for Large-Scale Phosphoproteome Analysis

article

Free water determines diffusion alterations and clinical status in cerebral small vessel disease

scientific article published in February 2018

From proteome lists to biological impact--tools and strategies for the analysis of large MS data sets

scientific article

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

scientific article published in Nature Communications

Gene-based pleiotropy across migraine with aura and migraine without aura patient groups

scientific article published on 8 December 2015

Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia.

scientific article

Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques

Genetic analysis for a shared biological basis between migraine and coronary artery disease

scientific article published on June 2015

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Genetic factors in cerebral small vessel disease and their impact on stroke and dementia

scientific article published on 22 April 2015

Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations

scientific article

Genetic overlap between diagnostic subtypes of ischemic stroke

scientific article

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies

scientific article published on 5 October 2012

Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants

scientific article published in the British Medical Journal

Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke

scientific article published in October 2017

Genetic variants related to antihypertensive targets inform drug efficacy and side effects

Genetic variation at 16q24.2 is associated with small vessel stroke

scientific article

Genetically predicted on-statin LDL response is associated with higher intracerebral haemorrhage risk

scientific article published on 22 May 2022

Genetically predicted on-statin LDL response is associated with higher intracerebral hemorrhage risk

scientific article published on 23 March 2022

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke

scientific article published in PLoS ONE

Genome-wide analysis of blood pressure variability and ischemic stroke

scientific article

Genome-wide association analysis identifies susceptibility loci for migraine without aura

scientific article

Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis

scientific article

Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke

scientific article

Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

scientific article published on 16 November 2020

Genome-wide genotyping demonstrates a polygenic risk score associated with white matter hyperintensity volume in CADASIL.

scientific article

Genome-wide meta-analysis identifies new susceptibility loci for migraine

scientific article

Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype

scientific article

Identification of a strategic brain network underlying processing speed deficits in vascular cognitive impairment

scientific article

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

scientific article published on 14 August 2014

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

scientific article

Loci influencing blood pressure identified using a cardiovascular gene-centric array

scientific article published on 8 January 2013

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

scientific article

Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration.

scientific article

Meta-Analysis of Genome-Wide Association Studies Identifies Genetic Risk Factors for Stroke in African Americans

scientific article

Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12.

scientific article

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

scientific article

Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage

scientific article

Modifiable pathways in Alzheimer's disease: Mendelian randomisation analysis

scientific article published on 6 December 2017

Multi-ethnic genome-wide association study for atrial fibrillation

article

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 12 March 2018

Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies

scientific article

Polygenic overlap between kidney function and large artery atherosclerotic stroke

scientific article

Polygenic risk of ischemic stroke is associated with cognitive ability

scientific article

Predicting stroke through genetic risk functions: the CHARGE Risk Score Project

scientific article (publication date: February 2014)

Prevalence of Amyloid Positron Emission Tomographic Positivity in Poststroke Mild Cognitive Impairment

scientific article published on 18 August 2016

Prevalence of cortical superficial siderosis in patients with cognitive impairment

scientific article

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

scientific article published on 01 July 2019

Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages

scientific article published in October 2009

RNA-Seq Identifies Circulating miR-125a-5p, miR-125b-5p, and miR-143-3p as Potential Biomarkers for Acute Ischemic Stroke

scientific article published on 19 July 2017

Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N = 112 151) and 24 GWAS consortia

article

Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants.

scientific article published in May 2015

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke

scientific article

Single nucleotide polymorphisms associated with rat expressed sequences

scientific article published on July 2004

Text mining and protein annotations: the construction and use of protein description sentences.

scientific article published in January 2006

The Plk1-dependent phosphoproteome of the early mitotic spindle

scientific article

The Subtype Specificity of Genetic Loci Associated with Stroke in 16,664 cases and 32,792 controls

The causal effect of vitamin D binding protein (DBP) levels on calcemic and cardiometabolic diseases: a Mendelian randomization study

scientific article (publication date: October 2014)

The migraine-stroke connection: A genetic perspective.

scientific article

Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology

scientific article

What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality:

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