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Authors whose works are in public domain in at least one jurisdiction

List of works by Hongbo Chi

1-50 of 99 results

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

scientific article

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

scientific article

mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function

scientific article published on 30 June 2013

Regulation and function of mTOR signalling in T cell fate decisions

scientific article published on April 20, 2012

The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.

scientific article published on 31 May 2009

The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.

scientific article

The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function

scientific article

Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.

scientific article

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

scientific article published on 24 March 2013

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

scientific article

T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming

scientific article published on 05 December 2013

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

scientific article published on 25 January 2016

mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.

scientific article published on 7 September 2016

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells.

scientific article published on 16 March 2014

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus

scientific article

Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination.

scientific article published on 08 September 2009

Metabolic control of regulatory T cell development and function

scientific article

COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence.

scientific article

Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis

scientific article

Sphingosine-1-phosphate and immune regulation: trafficking and beyond

scientific article

Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity

scientific article

Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells

scientific article published on 17 February 2012

Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation

scientific article published on 8 January 2012

Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation.

scientific article published on 3 March 2017

Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development.

scientific article

Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination

scientific article

The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells

scientific article

Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells.

scientific article

mTOR and metabolic pathways in T cell quiescence and functional activation

scientific article published on February 1, 2013

JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.

scientific article

GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.

scientific article published on 25 March 2004

mTOR and lymphocyte metabolism

scientific article published on May 28, 2013

Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling.

scientific article published on 23 August 2017

Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis

scientific article

Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation

scientific article published on 7 March 2016

iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions

scientific article published on 10 March 2014

Naturally activated V gamma 4 gamma delta T cells play a protective role in tumor immunity through expression of eomesodermin.

scientific article published on 04 June 2010

Acetylation of MKP-1 and the control of inflammation.

scientific article published on 14 October 2008

Targeted deletion of Minpp1 provides new insight into the activity of multiple inositol polyphosphate phosphatase in vivo

scientific article

Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs

scientific journal article

Cutting edge: Discrete functions of mTOR signaling in invariant NKT cell development and NKT17 fate decision.

scientific article published on 26 September 2014

mTOR signaling, Tregs and immune modulation

scientific article

mTOR signaling in the differentiation and function of regulatory and effector T cells.

scientific article published on 20 May 2017

Cutting edge: regulation of T cell trafficking and primary immune responses by sphingosine 1-phosphate receptor 1.

scientific article

Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells

scientific article published on 01 March 2007

Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells

scientific article published in Nature

Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates

scientific article

mTOR Links Environmental Signals to T Cell Fate Decisions.

scientific article

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.

scientific article

mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis.

scientific article