List of works - Hongbo Chi

JNK1 is essential for CD8+ T cell-mediated tumor immune surveillance.

scientific article published on November 2005

Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function.

scientific article published on 23 January 2012

Regulation of TH17 cell differentiation by innate immune signals

scientific article published on April 16, 2012

TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation.

scientific article

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.

scientific article published on 19 December 2018

Control of T Cell Fates and Immune Tolerance by p38α Signaling in Mucosal CD103+ Dendritic Cells

scientific article published on June 10, 2013

Metabolic coordination of T cell quiescence and activation

scientific article published on 12 August 2019

Mammalian Sterile 20-like Kinase 1 (Mst1) Enhances the Stability of Forkhead Box P3 (Foxp3) and the Function of Regulatory T Cells by Modulating Foxp3 Acetylation.

scientific article

mTOR signaling and transcriptional regulation in T lymphocytes

scientific article published on 21 February 2014

Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner.

scientific article published on 16 July 2015

mTOR and metabolic regulation of conventional and regulatory T cells.

scientific article

Innate recognition of non-self nucleic acids.

scientific article published on 10 March 2008

AMPK helps T cells survive nutrient starvation

scientific article published on January 2015

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells

scientific article published on 01 July 2018

Nutrient and Metabolic Sensing in T Cell Responses

scientific article published on 09 March 2017

Control of IL-17 receptor signaling and tissue inflammation by the p38α-MKP-1 signaling axis in a mouse model of multiple sclerosis

scientific article

Deprivation of MKK7 in cardiomyocytes provokes heart failure in mice when exposed to pressure overload

scientific article

Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis.

scientific article

I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection

scientific article published on 19 February 2013

Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells.

scientific article published on 05 August 2013

Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.

scientific article published on 7 August 2017

Helper T cell differentiation

scientific article published on 12 March 2019

Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas.

scientific article

Hallmarks of T-cell Exit from Quiescence

scientific article published in May 2018

Tuning mTOR activity for immune balance.

scientific article

LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity

scientific article published on 25 March 2019

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

scientific article

PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.

scientific article published on 13 November 2017

Dietary Fat Inflames CD4+ T Cell Memory in Obesity.

scientific article

Sensing the enemy within

scientific article published in Nature

Metabolism in Immune Cell Differentiation and Function.

scientific article published on January 2017

Gfi1-Foxo1 axis controls the fidelity of effector gene expression and developmental maturation of thymocytes

scientific article published on 19 December 2016

Genetic dissection of dendritic cell homeostasis and function: lessons from cell type-specific gene ablation

scientific article published on 24 December 2013

Investigating Cellular Quiescence of T Lymphocytes and Antigen-Induced Exit from Quiescence.

scientific article published in January 2018

Homeostasis and transitional activation of regulatory T cells require c-Myc

scientific article published on 01 January 2020

Gfi1: a unique controller of T(reg) cells.

scientific article published on 21 October 2013

Studies on MAP Kinase signaling in the immune system.

scientific article

Novel specialized cell state and spatial compartments within the germinal center

scientific article published on 27 April 2020

c-Myc and AP4: a relay team for metabolic reprogramming of CD8+ T cells

scientific article published on 01 September 2014

Autophagy modulates CD4+ T-cell lineage recommitment upon pathogen infection

scientific article published on 11 February 2020

CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity

scientific article published on 18 November 2021

Metabolic control of TFH cells and humoral immunity by phosphatidylethanolamine

scientific article published on 07 July 2021

Metabolic sleuthing solves a rare immunodeficiency disease

scientific article published on 01 October 2019

LCK senses asparagine for T cell activation

scientific article published in 2021

Metabolic adaptation of lymphocytes in immunity and disease

scientific article published in 2022

mTOR signaling at the crossroads of environmental signals and T-cell fate decisions

scientific article published on 25 March 2020

Sprouty branches out to control T cell memory

scientific article published on 4 September 2018

Lipid signalling enforces functional specialization of Treg cells in tumours

scientific article published on 24 February 2021

Metabolism and lymphocyte biology

scientific article published on 06 November 2015

List of works by Hongbo Chi

JNK1 is essential for CD8+ T cell-mediated tumor immune surveillance.

Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function.

Regulation of TH17 cell differentiation by innate immune signals

TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation.

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.

Control of T Cell Fates and Immune Tolerance by p38α Signaling in Mucosal CD103+ Dendritic Cells

Metabolic coordination of T cell quiescence and activation

Mammalian Sterile 20-like Kinase 1 (Mst1) Enhances the Stability of Forkhead Box P3 (Foxp3) and the Function of Regulatory T Cells by Modulating Foxp3 Acetylation.

mTOR signaling and transcriptional regulation in T lymphocytes

Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner.

mTOR and metabolic regulation of conventional and regulatory T cells.

Innate recognition of non-self nucleic acids.

AMPK helps T cells survive nutrient starvation

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells

Nutrient and Metabolic Sensing in T Cell Responses

Control of IL-17 receptor signaling and tissue inflammation by the p38α-MKP-1 signaling axis in a mouse model of multiple sclerosis

Deprivation of MKK7 in cardiomyocytes provokes heart failure in mice when exposed to pressure overload

Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis.

I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection

Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells.

Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.

Helper T cell differentiation

Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas.

Hallmarks of T-cell Exit from Quiescence

Tuning mTOR activity for immune balance.

LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.

Dietary Fat Inflames CD4+ T Cell Memory in Obesity.

Sensing the enemy within

Metabolism in Immune Cell Differentiation and Function.

Gfi1-Foxo1 axis controls the fidelity of effector gene expression and developmental maturation of thymocytes

Genetic dissection of dendritic cell homeostasis and function: lessons from cell type-specific gene ablation

Investigating Cellular Quiescence of T Lymphocytes and Antigen-Induced Exit from Quiescence.

Homeostasis and transitional activation of regulatory T cells require c-Myc

Gfi1: a unique controller of T(reg) cells.

Studies on MAP Kinase signaling in the immune system.

Novel specialized cell state and spatial compartments within the germinal center

c-Myc and AP4: a relay team for metabolic reprogramming of CD8+ T cells

Autophagy modulates CD4+ T-cell lineage recommitment upon pathogen infection

CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity

Metabolic control of TFH cells and humoral immunity by phosphatidylethanolamine

Metabolic sleuthing solves a rare immunodeficiency disease

LCK senses asparagine for T cell activation

Metabolic adaptation of lymphocytes in immunity and disease

mTOR signaling at the crossroads of environmental signals and T-cell fate decisions

Sprouty branches out to control T cell memory

Lipid signalling enforces functional specialization of Treg cells in tumours

Metabolism and lymphocyte biology