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List of works by Md Imtaiyaz Hassan

2/3D-QSAR, molecular docking and MD simulation studies of FtsZ protein targeting benzimidazoles derivatives

scientific article published on 27 December 2018

A novel multicopper oxidase (laccase) from cyanobacteria: Purification, characterization with potential in the decolorization of anthraquinonic dye

scientific article

A review of methods available to estimate solvent-accessible surface areas of soluble proteins in the folded and unfolded states

scientific article published on January 2014

A single mutation induces molten globule formation and a drastic destabilization of wild-type cytochrome c at pH 6.0.

scientific article published on 10 March 2009

A study of recombinant human sestrin 1 and sestrin 2 proteins produced in a prokaryotic system

scientific article published in May 2017

Advancements in docking and molecular dynamics simulations towards ligand-receptor interactions and structure-function relationships

scientific article published on 01 January 2018

An In Vitro elucidation of the antiaggregatory potential of Diosminover thermally induced unfolding of hen egg white lysozyme; A preventive quest for lysozyme amyloidosis

scientific article published on 19 February 2019

Antineoplastic Effects of Bee Honey and Nigella sativa on Hepatocellular Carcinoma Cells ⬇️

scientific article published on December 8, 2010

Aspergillus endocarditis: Diagnostic criteria and predictors of outcome, A retrospective cohort study

scientific article published in PLoS ONE

Atypical PKC phosphorylates microtubule affinity-regulating kinase 4 in vitro.

scientific article published on 7 September 2015

Backbone and side chain 1H, 15N and 13C chemical shift assignments of the molten globule state of L94G mutant of horse cytochrome-c

scientific article published on 04 November 2019

Binding mechanism of caffeic acid and simvastatin to the integrin linked kinase for therapeutic implications: a comparative docking and MD simulation studies

scientific article published on 11 January 2019

Binding studies and biological evaluation of β-carotene as a potential inhibitor of human calcium/calmodulin-dependent protein kinase IV.

scientific article published on 9 December 2016

Bioactive Phytoconstituents as Potent Inhibitors of Tyrosine-Protein Kinase Yes (YES1): Implications in Anticancer Therapeutics

scientific article published on 10 May 2022

Bioactive phytoconstituents as potent inhibitors of casein kinase-2: dual implications in cancer and COVID-19 therapeutics

scientific article published on 10 March 2022

Biological evaluation of p-toluene sulphonylhydrazone as carbonic anhydrase IX inhibitors: An approach to fight hypoxia-induced tumors

scientific article published on 19 August 2017

Biophysical Elucidation of Fibrillation Inhibition by Sugar Osmolytes in α-Lactalbumin: Multispectroscopic and Molecular Docking Approaches

scientific article published on 08 October 2020

Calcium/calmodulin-dependent protein kinase IV: A multifunctional enzyme and potential therapeutic target.

scientific article

Carbohydrate-Based Macromolecular Crowding-Induced Stabilization of Proteins: Towards Understanding the Significance of the Size of the Crowder

scientific article published on 12 September 2019

Carbonic anhydrase IX: A tumor acidification switch in heterogeneity and chemokine regulation

scientific article published in 2022

Characterisation of molten globule-like state of sheep serum albumin at physiological pH

scientific article published on 11 May 2016

Characterisation of mutations and molecular studies of type 2 von Willebrand disease

scientific article published on 22 November 2012

Characterization of folding intermediates during urea-induced denaturation of human carbonic anhydrase II.

scientific article

Characterization of intermediate state of myoglobin in the presence of PEG 10 under physiological conditions.

scientific article published on 24 February 2017

Characterization of pre-molten globule state of yeast iso-1-cytochrome c and its deletants at pH 6.0 and 25 °C

scientific article published on 04 November 2014

Chitinase from Thermomyces lanuginosus SSBP and its biotechnological applications

scientific article published on 13 October 2015

Classification and Functional Analyses of Putative Conserved Proteins from Chlamydophila pneumoniae CWL029.

scientific article published on 09 December 2015

Cloning, expression, purification and refolding of microtubule affinity-regulating kinase 4 expressed in Escherichia coli.

scientific article published on 21 January 2014

Comparative analysis of thermal unfolding simulations of RNA recognition motifs (RRMs) of TAR DNA-binding protein 43 (TDP-43).

scientific article published on 26 December 2017

Comparative analysis of web-based programs for single amino acid substitutions in proteins

scientific article published on 04 May 2022

Comparative studies on the aggregation behavior of HBPs from human seminal plasma by dynamic light scattering.

scientific article

Computing disease-linked SOD1 mutations: deciphering protein stability and patient-phenotype relations

scientific article

Conformational and thermodynamic characterization of the premolten globule state occurring during unfolding of the molten globule state of cytochrome c ⬇️

scientific article published on August 10, 2010

Cooperative Unfolding of Residual Structure in Heat Denatured Proteins by Urea and Guanidinium Chloride.

scientific article published on 5 June 2015

Correction: Aspergillus endocarditis: Diagnostic criteria and predictors of outcome, A retrospective cohort study

scientific article published in PLoS ONE

Correction: Aspergillus endocarditis: Diagnostic criteria and predictors of outcome, A retrospective cohort study

scientific article published on 27 November 2018

Correction: High Resolution Crystal Structure of Human β-Glucuronidase Reveals Structural Basis of Lysosome Targeting

scientific article published on 14 September 2015

Counteraction of the deleterious effects of urea on structure and stability of mammalian kidney proteins by osmolytes.

scientific article published on 10 October 2017

Curcumin specifically binds to the human calcium-calmodulin-dependent protein kinase IV: fluorescence and molecular dynamics simulation studies

scientific article

Current updates on computer aided protein modeling and designing.

scientific article

Data on the role of accessible surface area on osmolytes-induced protein stabilization

scientific article (publication date: February 2017)

Delineating the relationship between amyotrophic lateral sclerosis and frontotemporal dementia: Sequence and structure-based predictions

scientific article published on 15 June 2016

Denatured states of yeast cytochrome c induced by heat and guanidinium chloride are structurally and thermodynamically different

Design and Development of Novel Urea, Sulfonyltriurea, and Sulfonamide Derivatives as Potential Inhibitors of Sphingosine Kinase 1

scientific article published on 09 June 2020

Design and development of 5-(4H)-oxazolones as potential inhibitors of human carbonic anhydrase VA: towards therapeutic management of diabetes and obesity

scientific article published on 13 November 2020

Design and development of Isatin-triazole hydrazones as potential inhibitors of microtubule affinity-regulating kinase 4 for the therapeutic management of cell proliferation and metastasis

scientific article published on 13 December 2018

Design and synthesis of a novel class of carbonic anhydrase-IX inhibitor 1-(3-(phenyl/4-fluorophenyl)-7-imino-3H-[1,2,3]triazolo[4,5d]pyrimidin 6(7H)yl)urea

scientific article published on 21 January 2016

Design, synthesis and biological evaluation of novel pyridine-thiazolidinone derivatives as anticancer agents: Targeting human carbonic anhydrase IX.

scientific article published on 15 December 2017

Design, synthesis and validation of anti-microbial coumarin derivatives: An efficient green approach

scientific article published on 18 October 2019

Design, synthesis, and biological evaluation of pyrimidine derivatives as potential inhibitors of human calcium/calmodulin-dependent protein kinase IV.

scientific article published on 3 November 2016

Design, synthesis, in silico and biological evaluation of novel 2-(4-(4-substituted piperazin-1-yl)benzylidene)hydrazine carboxamides.

scientific article

Designing New Kinase Inhibitor Derivatives as Therapeutics Against Common Complex Diseases: Structural Basis of Microtubule Affinity-Regulating Kinase 4 (MARK4) Inhibition.

scientific article published on November 2015

Diagnostic approaches in COVID-19: clinical updates

scientific article published on 12 September 2020

Discovering a potent small molecule inhibitor for gankyrin using de novo drug design approach

scientific article published on December 24, 2011

Discovery of 4-(2-(dimethylamino)ethoxy)benzohydrazide derivatives as prospective microtubule affinity regulating kinase 4 inhibitors

scientific article published on 27 May 2020

Discovery of Hordenine as a Potential Inhibitor of Pyruvate Dehydrogenase Kinase 3: Implication in Lung Cancer Therapy

scientific article published on 14 May 2020

Effect of chemical denaturants on the conformational stability of GyrB subunit of DNA gyrase from Salmonella enterica serovar Typhi.

scientific article published on 9 May 2017

Effect of conservative mutations (L94V and L94I) on the structure and stability of horse cytochrome c.

scientific article

Effect of mammalian kidney osmolytes on the folding pathway of sheep serum albumin.

scientific article published on 21 January 2017

Effect of pH on structure, function, and stability of mitochondrial carbonic anhydrase VA

scientific article published on 04 April 2016

Effect of pH on the stability of hemochromatosis factor E: a combined spectroscopic and molecular dynamics simulation-based study

scientific article

Effect of pH on the structure, function, and stability of human calcium/calmodulin-dependent protein kinase IV: combined spectroscopic and MD simulation studies.

scientific article published on 22 January 2016

Effect of sequential deletion of extra N-terminal residues on the structure and stability of yeast iso-1-cytochrome-c.

scientific article

Effects of Pro1266Leu mutation on structure and function of glycoprotein Ib binding domain of von Willebrand factor

scientific article published on 28 May 2019

Ellagic Acid Controls Cell Proliferation and Induces Apoptosis in Breast Cancer Cells via Inhibition of Cyclin-Dependent Kinase 6 ⬇️

scientific article published on 15 May 2020

Elucidating the Impact of Deleterious Mutations on IGHG1 and Their Association with Huntington’s Disease

scientific article published in 2024

Elucidating the Interaction of Human Ferritin with Quercetin and Naringenin: Implication of Natural Products in Neurodegenerative Diseases: Molecular Docking and Dynamics Simulation Insight

scientific article published on 11 March 2021

Elucidation of Dietary Polyphenolics as Potential Inhibitor of Microtubule Affinity Regulating Kinase 4: In silico and In vitro Studies.

scientific article published on 25 August 2017

Elucidation of interaction mechanism of ellagic acid to the integrin linked kinase

scientific article published on 15 September 2018

Estimation of pH effect on the structure and stability of kinase domain of human integrin-linked kinase

scientific article published on 21 December 2017

Estimation of structure and stability of MurE ligase from Salmonella enterica serovar Typhi

scientific article published on 16 December 2017

Estimation of thermodynamic stability of human carbonic anhydrase IX from urea-induced denaturation and MD simulation studies.

scientific article published on 5 July 2017

Evaluation of Binding of Rosmarinic Acid with Human Transferrin and Its Impact on the Protein Structure: Targeting Polyphenolic Acid-Induced Protection of Neurodegenerative Disorders

scientific article published on 05 November 2020

Evaluation of binding and inhibition mechanism of dietary phytochemicals with sphingosine kinase 1: Towards targeted anticancer therapy

scientific article published on 10 December 2019

Evaluation of ellagic acid as an inhibitor of sphingosine kinase 1: A targeted approach towards anticancer therapy

scientific article published on 25 July 2019

Evaluation of human microtubule affinity-regulating kinase 4 inhibitors: fluorescence binding studies, enzyme, and cell assays.

scientific article published on 16 October 2016

Evaluation of pyrazolopyrimidine derivatives as microtubule affinity regulating kinase 4 inhibitors: Towards therapeutic management of Alzheimer's disease

scientific article published on 25 September 2019

Evidence of vanillin binding to CAMKIV explains the anti-cancer mechanism in human hepatic carcinoma and neuroblastoma cells.

scientific article published on 25 July 2017

Exploring Missense Mutations in Tyrosine Kinases Implicated with Neurodegeneration.

scientific article

First evidence of formation of pre-molten globule state in myoglobin: A macromolecular crowding approach towards protein folding in vivo

scientific article published on 23 December 2018

Fluorescent Dye Conjugates of Rabbit Arylsulfatase A as a Biological Tracer for Protein Endocytosis ⬇️

scientific article published on May 1, 2013

Folding and stability studies on C-PE and its natural N-terminal truncant

scientific article published on 13 January 2014

Functional annotation of conserved hypothetical proteins from Haemophilus influenzae Rd KW20

scientific article (publication date: 2013)

Functional annotation of putative hypothetical proteins from Candida dubliniensis

scientific article

Functional implications of pH-induced conformational changes in the Sphingosine kinase 1

scientific article published on 05 August 2019

Functional role of glutamine 28 and arginine 39 in double stranded RNA cleavage by human pancreatic ribonuclease

scientific article

GdmCl-induced unfolding studies of human carbonic anhydrase IX: a combined spectroscopic and MD simulation approach.

scientific article

GdnHCl-induced unfolding intermediate in the mitochondrial carbonic anhydrase VA.

scientific article published on 27 June 2016

Genome analysis of Chlamydia trachomatis for functional characterization of hypothetical proteins to discover novel drug targets.

scientific article published on 16 December 2016

Green Composites Based on Animal Fiber and Their Applications for a Sustainable Future

scientific article published in 2023

Heparin-binding proteins of human seminal plasma: purification and characterization

scientific article

Hesperidin-CAMKIV interaction and its impact on cell proliferation and apoptosis in the human hepatic carcinoma and neuroblastoma cells

scientific article published on 25 April 2019

Heterogeneity of equilibrium molten globule state of cytochrome c induced by weak salt denaturants under physiological condition.

scientific article published on 7 April 2015

High resolution crystal structure of human β-glucuronidase reveals structural basis of lysosome targeting

scientific article

High throughput screening, docking, and molecular dynamics studies to identify potential inhibitors of human calcium/calmodulin-dependent protein kinase IV

scientific article published on 01 November 2018

Human Disease Insight: An integrated knowledge-based platform for disease-gene-drug information

scientific article published on 26 November 2015

Human seminal proteinase and prostate-specific antigen are the same protein

scientific article published on 01 June 2008

Human β-glucuronidase: structure, function, and application in enzyme replacement therapy.

scientific article published on October 2013

Identification and Evaluation of Inhibitors of Lipase from using Virtual High-Throughput Screening and Molecular Dynamics Studies

scientific article published on 18 February 2019

Identification and evaluation of glutathione conjugate gamma-l-glutamyl-l-cysteine for improved drug delivery to the brain

scientific article published on 18 September 2019

Identification of High-Affinity Inhibitors of Cyclin-Dependent Kinase 2 Towards Anticancer Therapy

scientific article published on 15 December 2019

Identification of Potential Inhibitors of Calcium/Calmodulin-Dependent Protein Kinase IV from Bioactive Phytoconstituents

scientific article published on 16 July 2020

Identification of functional candidates amongst hypothetical proteins of Mycobacterium leprae Br4923, a causative agent of leprosy.

scientific article published on January 2015

Identification of functional candidates amongst hypothetical proteins of Treponema pallidum ssp. pallidum.

scientific article published on 20 April 2015

Identification of high-affinity inhibitors of pyruvate dehydrogenase kinase-3: towards therapeutic management of cancer

scientific article published on 14 January 2020

Identification of α-Mangostin as a Potential Inhibitor of Microtubule Affinity Regulating Kinase 4

scientific article published on 25 July 2019

Impact of Gln94Glu mutation on the structure and function of protection of telomere 1, a cause of cutaneous familial melanoma

scientific article published on 07 May 2019

Impact of glioblastoma multiforme associated mutations on the structure and function of MAP/microtubule affinity regulating kinase 4

scientific article published on 17 March 2020

Impact of non-synonymous mutations on the structure and function of telomeric repeat binding factor 1

scientific article published in 2021

Implications of molecular diversity of chitin and its derivatives.

scientific article published on 31 March 2017

In silico approaches for the identification of virulence candidates amongst hypothetical proteins of Mycoplasma pneumoniae 309.

scientific article published on 18 September 2015

In vitro and in silico studies of urea-induced denaturation of yeast iso-1-cytochrome c and its deletants at pH 6.0 and 25 °C

scientific article published on 23 September 2014

Infection Dynamics of ATG8 in <i>Leishmania</i>: Balancing Autophagy for Therapeutics

scientific article published on 13 May 2022

Inhibition of MARK4 by serotonin as an attractive therapeutic approach to combat Alzheimer's disease and neuroinflammation

scientific article published in 2022

Insight into the binding of PEG-400 with eye protein alpha-crystallin: Multi spectroscopic and computational approach: possible therapeutics targeting eye diseases

scientific article published on 11 December 2020

Insight of the Interaction between 2,4-thiazolidinedione and Human Serum Albumin: A Spectroscopic, Thermodynamic and Molecular Docking Study

scientific article published on 03 June 2019

Insights into the Conserved Regulatory Mechanisms of Human and Yeast Aging

scientific article published on 09 June 2020

InstaDock: A single-click graphical user interface for molecular docking-based virtual high-throughput screening

scientific article published on 26 October 2020

Interaction of DNA minor groove binder Hoechst 33258 with bovine serum albumin.

scientific article

Interactions Under Crowding Milieu: Chemical-Induced Denaturation of Myoglobin is Determined by the Extent of Heme Dissociation on Interaction with Crowders

scientific article published on 23 March 2020

Investigating host-virus interaction mechanism and phylogenetic analysis of viral proteins involved in the pathogenesis

scientific article published on 16 December 2021

Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach

scientific article published on 22 October 2021

Investigating the role of transcription factors of pancreas development in pancreatic cancer

scientific article published on 24 December 2017

Investigating the structural features of chromodomain proteins in the human genome and predictive impacts of their mutations in cancers

scientific article published on 24 March 2019

Investigation of conformational dynamics of Tyr89Cys mutation in protection of telomeres 1 gene associated with familial melanoma

scientific article published on 27 December 2019

Investigation of deleterious effects of nsSNPs in the POT1 gene: a structural genomics-based approach to understand the mechanism of cancer development

scientific article published on 16 December 2018

Investigation of inhibitory potential of quercetin to the pyruvate dehydrogenase kinase 3: Towards implications in anticancer therapy

scientific article published on 22 June 2019

Investigation of molecular mechanism of recognition between citral and MARK4: A newer therapeutic approach to attenuate cancer cell progression

scientific article published on 24 October 2017

Investigation of the role of central metal ion of Cyathus bulleri laccase 1 using guanidinium chloride-induced denaturation

scientific article published on 04 April 2019

Kinetic and Structural Studies on the Interactions of Heparin and Proteins of Human Seminal Plasma using Surface Plasmon Resonance ⬇️

scientific article published on August 1, 2012

Large scale analysis of the mutational landscape in β-glucuronidase: A major player of mucopolysaccharidosis type VII.

scientific article

Luminol-based chemiluminescent signals: clinical and non-clinical application and future uses.

scientific article published on 22 April 2014

MARK4 Inhibited by AChE Inhibitors, Donepezil and Rivastigmine Tartrate: Insights into Alzheimer's Disease Therapy

scientific article published on 20 May 2020

Macromolecular crowding induces molten globule state in the native myoglobin at physiological pH.

scientific article published on 12 August 2017

Mechanistic insights into the urea-induced denaturation of kinase domain of human integrin linked kinase

scientific article published on 5 January 2018

Microtubule affinity-regulating kinase 4: structure, function, and regulation.

scientific article

Mixture of Macromolecular Crowding Agents Has a Non-additive Effect on the Stability of Proteins

scientific article published on 09 February 2019

Molecular Modeling of Chemosensory Protein 3 from Spodoptera litura and Its Binding Property with Plant Defensive Metabolites

scientific article published on 06 June 2020

Molecular and macromolecular crowding-induced stabilization of proteins: Effect of dextran and its building block alone and their mixtures on stability and structure of lysozyme

scientific article published on 21 November 2019

Molecular basis of the structural stability of hemochromatosis factor E: A combined molecular dynamic simulation and GdmCl-induced denaturation study

scientific article published on 01 March 2016

Molecular interaction studies on ellagic acid for its anticancer potential targeting pyruvate dehydrogenase kinase 3

scientific article published on 29 July 2019

Molecular mechanism of Ras-related protein Rab-5A and effect of mutations in the catalytically active phosphate-binding loop

scientific article published on 4 January 2016

Molecular modeling and simulation of the human eNOS reductase domain, an enzyme involved in the release of vascular nitric oxide

scientific article published on 7 October 2014

Monocyclic β-lactam and unexpected oxazinone formation: synthesis, crystal structure, docking studies and antibacterial evaluation.

scientific article

Multispectroscopic and Molecular Docking Insight into Elucidating the Interaction of Irisin with Rivastigmine Tartrate: A Combinational Therapy Approach to Fight Alzheimer's Disease

scientific article published on 08 March 2021

Mutated CEACAMs Disrupt Transforming Growth Factor Beta Signaling and Alter the Intestinal Microbiome to Promote Colorectal Carcinogenesis

scientific article published on 01 October 2019

Neurodegenerative brain models vs. cell replacement or restoration therapy: A review on promises and pitfalls

scientific article published on 12 November 2021

Novel missense mutation in FHIT gene: interpreting the effect in HPV-mediated cervical cancer in Indian women.

scientific article published in February 2010

PKR-inhibitor binds efficiently with human microtubule affinity-regulating kinase 4.

scientific article published on 21 October 2015

Pharmacological features, health benefits and clinical implications of honokiol

scientific article published on 12 September 2022

Phosphorylation-induced changes in the energetic frustration in human Tank binding kinase 1.

scientific article published on 10 April 2018

Polo-like Kinase 1 as an emerging drug target: Structure, function and therapeutic implications

scientific article published on 04 September 2020

Probing pH sensitivity of αC-phycoerythrin and its natural truncant: A comparative study.

scientific article

Probing the Inhibition of Microtubule Affinity Regulating Kinase 4 by N-Substituted Acridones

scientific article published in Scientific Reports

Progastriscin: structure, function, and its role in tumor progression.

scientific article published on 15 March 2010

Protein aggregation and neurodegenerative diseases: From theory to therapy.

scientific article

Protein aggregation, misfolding and consequential human neurodegenerative diseases.

scientific article published on 23 January 2017

Protein folding: Molecular dynamics simulations and in vitro studies for probing mechanism of urea- and guanidinium chloride-induced unfolding of horse cytochrome-c

scientific article published on 30 October 2018

Protein stability: Determination of structure and stability of the transmembrane protein Mce4A from M. tuberculosis in membrane-like environment

scientific article published on 23 December 2018

Proteomic analysis of heparin-binding proteins from human seminal plasma: a step towards identification of molecular markers of male fertility

scientific article

Proteomic analysis of human amniotic fluid from Rh(-) pregnancy

scientific article

Proteomic approach for purification of seminal plasma proteins involved in tumor proliferation.

scientific article

Purification and characterization of Ras related protein, Rab5a from Tinospora cordifolia.

scientific article published on 27 October 2015

Purification and characterization of calreticulin: a Ca²⁺-binding chaperone from sheep kidney.

scientific article

Purification and characterization of oligonucleotide binding (OB)-fold protein from medicinal plant Tinospora cordifolia.

scientific article

Purification and characterization of zinc alpha2-glycoprotein-prolactin inducible protein complex from human seminal plasma

scientific article

Purification and structural characterization of Mce4A from Mycobacterium tuberculosis.

scientific article published on 26 June 2016

Purification, modeling and structural insights of calmodulin-binding receptor like cytoplasmic kinase 2 from Oroxylum Indicum

scientific article published on 07 November 2018

Purification, preliminary X-ray crystallography and biophysical studies of triose phosphate isomerase-β-globin subunit complex.

scientific article

QSAR based therapeutic management of M. tuberculosis.

scientific article published on 29 April 2017

Relationship between protein stability and functional activity in the presence of macromolecular crowding agents alone and in mixture: An insight into stability-activity trade-off

scientific article published on 29 August 2015

Role of N-terminal residues on folding and stability of C-phycoerythrin: simulation and urea-induced denaturation studies.

scientific article published on 27 November 2013

Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition

scientific article published on 25 June 2020

SARS-CoV-2 mediated lung inflammatory responses in host: targeting the cytokine storm for therapeutic interventions

scientific article published on 16 October 2020

Search of potential inhibitor against New Delhi metallo-beta-lactamase 1 from a series of antibacterial natural compounds ⬇️

scientific article published on January 1, 2013

Sequence and stability of the goat cytochrome c.

scientific article published on 4 September 2008

Sequence, structure and evolutionary analysis of cold shock domain proteins, a member of OB fold family

scientific article published on 19 October 2018

Size-dependent studies of macromolecular crowding on the thermodynamic stability, structure and functional activity of proteins: in vitro and in silico approaches.

scientific article published on 11 November 2016

Solvent sensitivity of protein aggregation in Cu, Zn superoxide dismutase: a molecular dynamics simulation study.

scientific article published on 6 August 2017

Spectroscopic and MD simulation studies on unfolding processes of mitochondrial carbonic anhydrase VA induced by urea

scientific article published on 27 January 2016

Spectroscopic, calorimetric and molecular docking insight into the interaction of Alzheimer's drug donepezil with human transferrin: implications of Alzheimer's drug

scientific article published on 02 April 2019

Strategy for sensitive and specific detection of molecular forms of PSA based on 2DE and kinetic analysis: a step towards diagnosis of prostate cancer

scientific article

Structural Analysis and Conformational Dynamics of STN1 Gene Mutations Involved in Coat Plus Syndrome.

scientific article published on 12 June 2019

Structural Features of Nucleoprotein CST/Shelterin Complex Involved in the Telomere Maintenance and Its Association with Disease Mutations

scientific article published on 04 February 2020

Structural and functional analysis of various globulin proteins from soy seed.

scientific article

Structural and functional impact of non-synonymous SNPs in the CST complex subunit TEN1: structural genomics approach

scientific article published on 15 May 2019

Structural and thermodynamic characterisation of L94F mutant of horse cytochrome c.

scientific article published in July 2016

Structural basis of urea-induced unfolding: Unraveling the folding pathway of hemochromatosis factor E.

scientific article published on 20 June 2016

Structural characterization of MG and pre-MG states of proteins by MD simulations, NMR, and other techniques

scientific article

Structural diversity of class I MHC-like molecules and its implications in binding specificities.

scientific article published on January 2011

Structural insight into C9orf72 hexanucleotide repeat expansions: Towards new therapeutic targets in FTD-ALS.

scientific article

Structure and function of von Willebrand factor

scientific article published on 01 January 2012

Structure guided design of potential inhibitors of human calcium-calmodulin dependent protein kinase IV containing pyrimidine scaffold

scientific article published on 30 December 2015

Structure prediction and functional analyses of a thermostable lipase obtained from Shewanella putrefaciens

scientific article

Structure-Guided Approach to Identify Potential Inhibitors of Large Envelope Protein to Prevent Hepatitis B Virus Infection

scientific article published on 04 September 2019

Structure-based function analysis of putative conserved proteins with isomerase activity from Haemophilus influenzae.

scientific article published on 28 December 2014

Structure-based functional annotation of hypothetical proteins from Candida dubliniensis: a quest for potential drug targets ⬇️

scientific article published on 17 October 2014

Structure-based identification of potential SARS-CoV-2 main protease inhibitors

scientific article published on 19 November 2020

Synthesis, characterization and biological evaluation of tertiary sulfonamide derivatives of pyridyl-indole based heteroaryl chalcone as potential carbonic anhydrase IX inhibitors and anticancer agents

scientific article published on 22 May 2018

Synthesis, estrogen receptor binding affinity and molecular docking of pyrimidine-piperazine-chromene and -quinoline conjugates.

scientific article published on 29 July 2017

Synthesis, molecular docking and inhibition studies of novel 3-N-aryl substituted-2-heteroarylchromones targeting microtubule affinity regulating kinase 4 inhibitors

scientific article published on 27 September 2018

Targeting metacaspase-3 from Plasmodium falciparum towards antimalarial therapy: A combined approach of in-silico and in-vitro investigation

scientific article published on 13 January 2020

Testing the ability of non-methylamine osmolytes present in kidney cells to counteract the deleterious effects of urea on structure, stability and function of proteins.

scientific article

Testing the dependence of stabilizing effect of osmolytes on the fractional increase in the accessible surface area on thermal and chemical denaturations of proteins

scientific article published on 11 December 2015

The SARS Coronavirus 3a protein binds calcium in its cytoplasmic domain

scientific article published on 10 August 2014

The pH Dependence of Saccharides' Influence on Thermal Denaturation of Two Model Proteins Supports an Excluded Volume Model for Stabilization Generalized to Allow for Intramolecular Electrostatic Interactions

scientific article

The role of key residues in structure, function, and stability of cytochrome-c.

scientific article published on 25 April 2013

The structural basis of acid resistance in Mycobacterium tuberculosis: insights from multiple pH regime molecular dynamics simulations

scientific article published on 08 November 2019

Therapeutic progress in amyotrophic lateral sclerosis-beginning to learning

scientific article published on 14 June 2016

Thermal Stabilization of Proteins by Mono- and Oligosaccharides: Measurement and Analysis in the Context of an Excluded Volume Model

scientific article published on 03 June 2015

Thienopyrimidine-Chalcone Hybrid Molecules Inhibit Fas-Activated Serine/Threonine Kinase: An Approach To Ameliorate Antiproliferation in Human Breast Cancer Cells

scientific article published on 07 August 2018

Towards New Drug Targets? Function Prediction of Putative Proteins of Neisseria meningitidis MC58 and Their Virulence Characterization

scientific article published on 15 June 2015

Towards understanding cellular structure biology: In-cell NMR.

scientific article published on 28 February 2017

Ubiquitin-associated domain of MARK4 provides stability at physiological pH.

scientific article published on 24 September 2016

Understanding the role and mechanism of carbonic anhydrase V in obesity and its therapeutic implications

scientific article published on 10 August 2017

Unfoldness of the denatured state of proteins determines urea: Methylamine counteraction in terms of Gibbs free energy of stabilization

scientific article published on 01 April 2019

Unraveling Binding Mechanism of Alzheimer's Drug Rivastigmine Tartrate with Human Transferrin: Molecular Docking and Multi-Spectroscopic Approach towards Neurodegenerative Diseases

scientific article published on 17 September 2019

Unraveling the Role of RNA Mediated Toxicity of C9orf72 Repeats in C9-FTD/ALS.

scientific article published on 15 December 2017

Unravelling the unfolding mechanism of human integrin linked kinase by GdmCl-induced denaturation.

scientific article

Unravelling the unfolding pathway of human Fas-activated serine/threonine kinase induced by urea

scientific article published on 14 July 2020

Urea-induced denaturation of human calcium/calmodulin-dependent protein kinase IV: a combined spectroscopic and MD simulation studies.

scientific article published on 2 February 2016

Ventricular Function in Patients with End‐Stage Renal Disease Starting Dialysis Therapy: A Tissue Doppler Imaging Study ⬇️

scientific article published on June 5, 2012

Virtual Screening Approach to Identify High-Affinity Inhibitors of Serum and Glucocorticoid-Regulated Kinase 1 among Bioactive Natural Products: Combined Molecular Docking and Simulation Studies

scientific article published on 13 February 2020

Zinc alpha 2-glycoprotein: a multidisciplinary protein.

scientific article published on June 2008

β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development

scientific article published on 15 December 2021

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