List of works - Bo Ahrén

Galanin: a novel pancreatic neuropeptide

scientific article published on 01 July 1986

The apj receptor is expressed in pancreatic islets and its ligand, apelin, inhibits insulin secretion in mice

scientific article

Pituitary adenylate cyclase-activating polypeptide (PACAP): occurrence in rodent pancreas and effects on insulin and glucagon secretion in the mouse

scientific article published on August 1, 1992

Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men.

scientific article

Glucose-dependent arginine stimulation test for characterization of islet function: studies on reproducibility and priming effect of arginine

scientific article published on July 1, 1998

Inhibitors of dipeptidyl peptidase IV: a novel approach for the prevention and treatment of Type 2 diabetes?

scientific article published in September 2004

Changes in prandial glucagon levels after a 2-year treatment with vildagliptin or glimepiride in patients with type 2 diabetes inadequately controlled with metformin monotherapy

scientific article

Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice

scientific article

Incretin, insulinotropic and glucose-lowering effects of whey protein pre-load in type 2 diabetes: a randomised clinical trial

scientific article published on 10 July 2014

Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice

scientific article published on 01 January 1997

Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice

scientific article published on 20 April 2006

Clinical results of treating type 2 diabetic patients with sitagliptin, vildagliptin or saxagliptin--diabetes control and potential adverse events

scientific article published on August 2009

Glucagon-like peptide-1 reduces hepatic glucose production indirectly through insulin and glucagon in humans

article

Estimated intake of milk fat is negatively associated with cardiovascular risk factors and does not increase the risk of a first acute myocardial infarction. A prospective case-control study

scientific article published in April 2004

Liver-derived IGF-I is of importance for normal carbohydrate and lipid metabolism.

scientific article

DPP-4 inhibitors

scientific article

Neuropeptide Y: intrapancreatic neuronal localization and effects on insulin secretion in the mouse

scientific article published on 01 April 1987

Calcitonin gene-related peptide: occurrence in pancreatic islets in the mouse and the rat and inhibition of insulin secretion in the mouse

scientific article

GPR40 is expressed in glucagon producing cells and affects glucagon secretion

scientific article published on 3 January 2007

Vildagliptin reduces glucagon during hyperglycemia and sustains glucagon counterregulation during hypoglycemia in type 1 diabetes

scientific article

Short-term dexamethasone treatment increases plasma leptin independently of changes in insulin sensitivity in healthy women

scientific article published in December 1996

Dual action of adiponectin on insulin secretion in insulin-resistant mice

scientific article published in August 2004

Increased β-cell volume in mice fed a high-fat diet: a dynamic study over 12 months

scientific article published on November 1, 2010

Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance

scientific article

Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet.

scientific article published on 11 November 2004

Physiology of Incretins in Health and Disease

scientific article published on November 10, 2011

Sympathetic nerve stimulation versus pancreatic norepinephrine infusion in the dog: 1). Effects on basal release of insulin and glucagon

scientific article published on 01 July 1987

Diabetes and impaired fasting glycemia in a rural population of Bangladesh

scientific article published in April 2003

Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function

scientific article published on 01 December 2006

Plasma leptin levels correlate to islet function independently of body fat in postmenopausal women

scientific article published in November 1996

The mechanism of vagal nerve stimulation of glucagon and insulin secretion in the dog

scientific article published on 01 April 1986

Identification, isolation, and characterization of daintain (allograft inflammatory factor 1), a macrophage polypeptide with effects on insulin secretion and abundantly present in the pancreas of prediabetic BB rats

scientific article

Clinical characteristics, treatment and survival in patients with pancreatic tumors causing hormonal syndromes

scientific article published on July 1, 1992

Surrogate measures of insulin sensitivity vs the hyperinsulinaemic-euglycaemic clamp: a meta-analysis

scientific article published on 3 June 2014

Gut peptides and type 2 diabetes mellitus treatment

scientific article

Plasma leptin levels are associated with abnormal fibrinolysis in men and postmenopausal women

scientific article

CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight

scientific article published in July 2005

Sensory nerves contribute to insulin secretion by glucagon-like peptide-1 in mice

scientific article published in February 2004

Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin

scientific article published on March 1, 2011

Low serum insulin in traditional Pacific Islanders--the Kitava Study

scientific article published on October 1999

Role of VIP and PACAP in islet function

scientific article

Altered beta-cell distribution of pdx-1 and GLUT-2 after a short-term challenge with a high-fat diet in C57BL/6J mice

scientific article

Insufficient islet compensation to insulin resistance vs. reduced glucose effectiveness in glucose-intolerant mice

scientific article published in October 2002

High leptin levels are associated with stroke

scientific article published in January 2003

Impaired glucose tolerance (IGT) is associated with reduced insulin-induced suppression of glucagon concentrations

scientific article published on November 1, 2001

Islet adaptation to insulin resistance: mechanisms and implications for intervention

scientific article

GLP-1 tablet in type 2 diabetes in fasting and postprandial conditions

scientific article published on December 1997

The islet enhancer vildagliptin: mechanisms of improved glucose metabolism

scientific article published on March 2008

Effect of a conjugated linoleic acid and omega-3 fatty acid mixture on body composition and adiponectin

scientific article

Important role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta-cell exocytosis and release of insulin

scientific journal article

List of works by Bo Ahrén

Galanin: a novel pancreatic neuropeptide

The apj receptor is expressed in pancreatic islets and its ligand, apelin, inhibits insulin secretion in mice

Pituitary adenylate cyclase-activating polypeptide (PACAP): occurrence in rodent pancreas and effects on insulin and glucagon secretion in the mouse

Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men.

Glucose-dependent arginine stimulation test for characterization of islet function: studies on reproducibility and priming effect of arginine

Inhibitors of dipeptidyl peptidase IV: a novel approach for the prevention and treatment of Type 2 diabetes?

Changes in prandial glucagon levels after a 2-year treatment with vildagliptin or glimepiride in patients with type 2 diabetes inadequately controlled with metformin monotherapy

Contribution to glucose tolerance of insulin-independent vs. insulin-dependent mechanisms in mice

Incretin, insulinotropic and glucose-lowering effects of whey protein pre-load in type 2 diabetes: a randomised clinical trial

Dissociated insulinotropic sensitivity to glucose and carbachol in high-fat diet-induced insulin resistance in C57BL/6J mice

Glucose-induced incretin hormone release and inactivation are differently modulated by oral fat and protein in mice

Clinical results of treating type 2 diabetic patients with sitagliptin, vildagliptin or saxagliptin--diabetes control and potential adverse events

Glucagon-like peptide-1 reduces hepatic glucose production indirectly through insulin and glucagon in humans

Estimated intake of milk fat is negatively associated with cardiovascular risk factors and does not increase the risk of a first acute myocardial infarction. A prospective case-control study

Liver-derived IGF-I is of importance for normal carbohydrate and lipid metabolism.

DPP-4 inhibitors

Neuropeptide Y: intrapancreatic neuronal localization and effects on insulin secretion in the mouse

Calcitonin gene-related peptide: occurrence in pancreatic islets in the mouse and the rat and inhibition of insulin secretion in the mouse

GPR40 is expressed in glucagon producing cells and affects glucagon secretion

Vildagliptin reduces glucagon during hyperglycemia and sustains glucagon counterregulation during hypoglycemia in type 1 diabetes

Short-term dexamethasone treatment increases plasma leptin independently of changes in insulin sensitivity in healthy women

Dual action of adiponectin on insulin secretion in insulin-resistant mice

Increased β-cell volume in mice fed a high-fat diet: a dynamic study over 12 months

Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance

Bovine growth hormone transgenic mice are resistant to diet-induced obesity but develop hyperphagia, dyslipidemia, and diabetes on a high-fat diet.

Physiology of Incretins in Health and Disease

Sympathetic nerve stimulation versus pancreatic norepinephrine infusion in the dog: 1). Effects on basal release of insulin and glucagon

Diabetes and impaired fasting glycemia in a rural population of Bangladesh

Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function

Plasma leptin levels correlate to islet function independently of body fat in postmenopausal women

The mechanism of vagal nerve stimulation of glucagon and insulin secretion in the dog

Identification, isolation, and characterization of daintain (allograft inflammatory factor 1), a macrophage polypeptide with effects on insulin secretion and abundantly present in the pancreas of prediabetic BB rats

Clinical characteristics, treatment and survival in patients with pancreatic tumors causing hormonal syndromes

Surrogate measures of insulin sensitivity vs the hyperinsulinaemic-euglycaemic clamp: a meta-analysis

Gut peptides and type 2 diabetes mellitus treatment

Plasma leptin levels are associated with abnormal fibrinolysis in men and postmenopausal women

CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight

Sensory nerves contribute to insulin secretion by glucagon-like peptide-1 in mice

Clinical evidence and mechanistic basis for vildagliptin's action when added to metformin

Low serum insulin in traditional Pacific Islanders--the Kitava Study

Role of VIP and PACAP in islet function

Altered beta-cell distribution of pdx-1 and GLUT-2 after a short-term challenge with a high-fat diet in C57BL/6J mice

Insufficient islet compensation to insulin resistance vs. reduced glucose effectiveness in glucose-intolerant mice

High leptin levels are associated with stroke

Impaired glucose tolerance (IGT) is associated with reduced insulin-induced suppression of glucagon concentrations

Islet adaptation to insulin resistance: mechanisms and implications for intervention

GLP-1 tablet in type 2 diabetes in fasting and postprandial conditions

The islet enhancer vildagliptin: mechanisms of improved glucose metabolism

Effect of a conjugated linoleic acid and omega-3 fatty acid mixture on body composition and adiponectin

Important role of phosphodiesterase 3B for the stimulatory action of cAMP on pancreatic beta-cell exocytosis and release of insulin