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List of works by Bo Ahrén

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Interleukin-6-deficient mice develop mature-onset obesity

scientific article published in January 2002
The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetes

scientific article
Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease

scientific article
Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus

scientific article
Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes

scientific article
Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes

scientific article published on 14 April 2009
Islet amyloid and type 2 diabetes mellitus

scientific article
Twelve- and 52-week efficacy of the dipeptidyl peptidase IV inhibitor LAF237 in metformin-treated patients with type 2 diabetes

scientific article published in December 2004
Fifty-two-week efficacy and safety of vildagliptin vs. glimepiride in patients with type 2 diabetes mellitus inadequately controlled on metformin monotherapy

scientific article published in February 2009
Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4-week study period in type 2 diabetes

scientific article published in May 2002
Evidence that oestrogen receptor-alpha plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver

scientific article published on 4 February 2006
Dipeptidyl peptidase‐4 inhibitors and cardiovascular risk: a meta‐analysis of randomized clinical trials

scientific article published on September 20, 2012
Alpha cell function in health and disease: influence of glucagon-like peptide-1.

scientific article
Leptin is associated with increased risk of myocardial infarction

scientific article
Improved meal-related beta-cell function and insulin sensitivity by the dipeptidyl peptidase-IV inhibitor vildagliptin in metformin-treated patients with type 2 diabetes over 1 year

scientific article published in August 2005
Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion

scientific article published on December 1986
Advancing Basal Insulin Replacement in Type 2 Diabetes Inadequately Controlled With Insulin Glargine Plus Oral Agents: A Comparison of Adding Albiglutide, a Weekly GLP-1 Receptor Agonist, Versus Thrice-Daily Prandial Insulin Lispro

scientific article published on June 4, 2014
HARMONY 3: 104-Week Randomized, Double-Blind, Placebo- and Active-Controlled Trial Assessing the Efficacy and Safety of Albiglutide Compared With Placebo, Sitagliptin, and Glimepiride in Patients With Type 2 Diabetes Taking Metformin

scientific article published on June 4, 2014
Vildagliptin add-on to metformin produces similar efficacy and reduced hypoglycaemic risk compared with glimepiride, with no weight gain: results from a 2-year study

scientific article published on September 2010
The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia

scientific article
Dose-dependent inhibition by ghrelin of insulin secretion in the mouse

scientific article published in March 2003
Autonomic mediation of glucagon secretion during hypoglycemia: implications for impaired alpha-cell responses in type 1 diabetes

scientific article published on July 1, 1998
In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse: pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells

scientific article published in February 2006
G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes

scientific article
Vildagliptin enhances islet responsiveness to both hyper- and hypoglycemia in patients with type 2 diabetes

scientific article published on 27 January 2009
Gastric carcinoids: biologic behavior and prognosis after differentiated treatment in relation to type

scientific article published on 01 July 2005
Efficacy and Safety of Lixisenatide Once-Daily Morning or Evening Injections in Type 2 Diabetes Inadequately Controlled on Metformin (GetGoal-M)

scientific article published on March 27, 2013
Importance of quantifying insulin secretion in relation to insulin sensitivity to accurately assess beta cell function in clinical studies

scientific article published on February 2004
Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study

scientific article
Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men.

scientific article published in September 2001
Mature-Onset Obesity in Interleukin-1 Receptor I Knockout Mice

scientific article published on 01 May 2006
Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes-a review and meta analysis

scientific article
Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model

scientific article
Mechanisms of action of the dipeptidyl peptidase-4 inhibitor vildagliptin in humans

scientific article published on September 1, 2011
A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease

scientific article
Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2): a 56-week, double-blind, phase 3a, randomised trial

scientific article
Incretin and islet hormonal responses to fat and protein ingestion in healthy men.

scientific article published on 8 July 2008
Increased Insulin Secretion and Glucose Tolerance in Mice Lacking Islet Amyloid Polypeptide (Amylin)

scientific article published on September 18, 1998
GLP-1 receptor agonists and DPP-4 inhibitors in the treatment of type 2 diabetes

scientific article
Leptin is a risk marker for first-ever hemorrhagic stroke in a population-based cohort

scientific article
Dipeptidyl peptidase-4 inhibitors: clinical data and clinical implications

scientific article
Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice

scientific article published in May 2002
Avoiding hypoglycemia: a key to success for glucose-lowering therapy in type 2 diabetes

scientific article published on April 24, 2013
Improved glucose tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice

scientific article
Galanin-receptor ligand M40 peptide distinguishes between putative galanin-receptor subtypes

scientific article published on December 1993
Incretin hormone and insulin responses to oral versus intravenous lipid administration in humans

scientific article published on 18 May 2011
Growth hormone deficiency predicts cardiovascular risk in young adults treated for acute lymphoblastic leukemia in childhood

scientific article published in October 2004
Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes

scientific article published in January 2007
Improved beta-cell function after standardized weight reduction in severely obese subjects

scientific article
Hormone-sensitive lipase null mice exhibit signs of impaired insulin sensitivity whereas insulin secretion is intact

scientific article published on 30 June 2003

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